scholarly journals A study of etiology and epidemiology of onychomycosis from a tertiary care hospital in North India

2021 ◽  
Vol 9 (2) ◽  
pp. 559
Author(s):  
Shivani Tyagi ◽  
Neha . ◽  
Ravinder Kaur ◽  
Deepti Rawat
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Trichophyton Mentagrophytes ◽  
North India ◽  
Care Hospital ◽  
Candida Spp ◽  
Dermatology Department ◽  
Age Related ◽  
Etiological Agents

Background: Onychomycosis is the fungal infec­tion of nail of which the incidence varies from 0.5-12% in India and around 5% worldwide.Onychomycosis is considered to be gender and age-related disease, being commoner in males and older adults in both genders. Apart from dermatophytes, other fungal agents like yeasts and non-dermatophyte moulds are increasingly being acknowledged as important etiological agents for the same. Our aim was to study the etiology of the nail infections in patients presenting to a dermatology department in a tertiary care hospital in central Delhi.Methods: This study included nail samples from patients of various age groups with suspected onychomycosis attending dermatology clinics in our hospital over a period of 2 years. For all samples, KOH wet mount microscopic examination followed by culture on Sabouraud’s dextrose agar was done. Growth of filamentous fungi and yeast obtained on SDA were identified using conventional microbiology techniques. Statistical analysis was performed using Epitools.Results: Of the total 1061 nail samples received, maximum prevalence seen in patients of age group 21 to 50 years. The positivity of onychomycosis was 57.02%. Out of culture positive samples, 24.62% grew dermatophytes and 75.37% grew non-dermatophytes (31.40% yeasts and 43.97% non-dermatophyte moulds). Trichophyton mentagrophytes was the most common (59.73%) dermatophyte followed by T. rubrum (23.49%) while among non-dermatophyte moulds; Aspergillus niger (20.68%) was the most common followed by A. flavus (16.54%) and others. Common yeasts included Candida spp. (65.79%) and Trichosporon spp. (28.95%).Conclusions: Non- dermatophytes are emerging as major etiological agents of onychomycosis which may be accounted various host factors. So, it becomes important to correctly identify the causative fungi to ensure appropriate treatment.

scholarly journals AGE AND GENDER RELATED MORTALITY AND OUTCOME OF COVID 19 POSITIVE PATIENTS

2021 ◽  
Vol 9 (12) ◽  
pp. 696-702
Author(s):  
Suhail Mansoor ◽  
◽  
Ghulam Jeelani Romshoo ◽  
Abroo Bashir ◽  
◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Care Hospital ◽  
Age Group ◽  
Age And Gender ◽  
Male And Female ◽  
Age Related ◽  
And Gender ◽  
Related Mortality

Background: This study was aimed to evaluate the age and gender related mortality and outcome of covid 19 positive patients in order to further strengthen the management of covid 19 patients as the insights from these data will be useful in determining preventive measures and treatment policies of covid 19 patients. Methodology: This was a retrospective observational study done in adult covid positive patients admitted in Tertiary Care Hospital from first May 2020 to 30 June 2021.The age related mortality and outcome in these patients was analyzed. Results: A total of 816 adult covid -19 positive patients were admitted in a Tertiary care hospital,GMC Anantnag from May 2020 to June 2021. Among the patients, 53.55 % were males and 46.44 % were females. The mean of the age involved was 57.96 years. The most common presenting symptom was fever (85%) followed by cough (70%) and shortness of breath (40%). Approximately 20% of patients presented with nonspecific complaints (including generalized aches, pains, body aches, myalgias etc). All age groups were affected equally (29% in 15-50yr, 37% in 51-65yr, 33% in 66-100yr). Maximum patients (70% ) affected were more than 50 yr of age. About 73.4% were discharged, 6% were reffered, 20% expired. So, overall hospital mortality was 20%. Further, Maximum (86%) of covid positive patients expired in age group of above 50 yrs. Further, Male and Female Mortality was also same in covid positive patients. Conclusion: Males and females were affected equally by Covid -19 disease with no sex predilection.. Fever was the main presenting symptom. All age groups were affected equally but mortality was more in elderly age group. Further, mortality is same in male and female covid positive patients with no gender predilection.

The Spectrum of Skin Biopsies from a Tertiary Care Hospital in North India

2016 ◽  
Vol 2 (5) ◽  
Author(s):  
Abhilasha Williams ◽  
Anuradha Bhatia ◽  
EmyAbi Thomas ◽  
Clarence J Samuel
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Skin Biopsies

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India (Preprint)

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)

Epidemiology and clinical outcome of ventilator-associated events at a tertiary care hospital from North India

2020 ◽  
pp. 004947552098245
Author(s):  
Pooja Kumari ◽  
Priya Datta ◽  
Satinder Gombar ◽  
Deepak Sharma ◽  
Jagdish Chander
Keyword(s):  
Mechanical Ventilation ◽  
Tertiary Care Hospital ◽  
Late Onset ◽  
Tertiary Care ◽  
Control Measures ◽  
North India ◽  
Ventilator Associated Pneumonia ◽  
Care Hospital ◽  
Infection Control Measures ◽  
Utilisation Rate

The aim of our study was to determine the incidence, microbiological profile, risk factors and outcomes of patients diagnosed with ventilator-associated events in our tertiary care hospital. In this prospective study, intensive care patients put on mechanical ventilation for >48 h were enrolled and monitored daily for ventilator-associated event according to Disease Centre Control guidelines. A ventilator-associated event developed in 33/250 (13.2%); its incidence was 3.5/100 mechanical ventilation days. The device utilisation rate was 0.86, 36.4% of patients had early and 63.6% late-onset ventilator-associated pneumonia whose most common causative pathogen was Acinetobacter sp. (63.6%). Various factors were significantly associated with a ventilator-associated event: male gender, COPD, smoking, >2 underlying diseases, chronic kidney disease and elevated acute physiological and chronic health evaluation II scores. Therefore, stringent implementation of infection control measures is necessary to control ventilator-associated pneumonia in critical care units.

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