scholarly journals A study the profile of pathological disorders resulting in acute abdominal non-traumatic surgical emergencies in a tertiary care hospital, North India

2018 ◽  
Vol 5 (2) ◽  
pp. 614
Author(s):  
Mohamamd Zahid ◽  
Mohd Arshad Raza ◽  
Manjul Mohan ◽  
Ranjan Agrawal ◽  
Pramod Kumar
Keyword(s):  
Tertiary Care ◽  
Exploratory Laparotomy ◽  
Sudden Onset ◽  
North India ◽  
Patch Repair ◽  
Treatment Modalities ◽  
Care Hospital ◽  
Surgical Emergencies ◽  
High Index Of Suspicion ◽  
Surgery Department

Background: Acute abdomen has a sudden onset, can persist for several hours to days and is associated with wide variety of clinical features requiring evaluation and treatment. The present study has been done to establish the etiopathological details and diagnostic verification of the patients presenting with non-traumatic pain in abdomen. Also, the management and admitted care of non-traumatic abdominal surgical emergencies and their outcome has been discussed.Methods: A prospective observational study was done in Rohilkhand Medical College and Hospital (RMCH) during November 2015 to October 2016. The study includes acute abdominal non-traumatic surgical emergencies presenting in general surgery department. All the data were analyzed through SPSS 22.Results: A total of 182 patients were included in the study. The most common complaint among patients was pain in abdomen followed by constipation and vomiting. The most common cases were intestinal perforation (57%) followed by acute appendicitis (14.89%), acute pancreatitis (9.34%), acute intestinal obstruction (9.34%) and others. Most common treatment modalities applied were Exploratory Laparotomy with true Graham’s patch repair (30.22%), non-operative/conservative treatment (26.92%) and Exploratory Laparotomy with ileostomy (13.19%). Total 13 cases (7.14%) expired (all post-operatively) and 8 cases (4.39%) developed major complications.Conclusions: The clinical course and outcome of acute abdominal emergencies in present study showed that a judicious and careful use of clinical evaluation with high index of suspicion along with radiological and biochemical findings help to reach a diagnosis based on which the appropriate management strategy ensures good outcome.

scholarly journals Compliance to advocated therapeutics in and head and neck oncosurgery clinic in a tertiary health care facility in North India: a pilot study

2020 ◽  
Vol 7 (8) ◽  
pp. 3042
Author(s):  
Manish Munjal ◽  
Japneet Kaur ◽  
Nitika Tuli ◽  
Porshia Rishi ◽  
Harjinder Sidhu ◽  
...  
Keyword(s):  
Head And Neck ◽  
Head And Neck Neoplasms ◽  
Surgical Intervention ◽  
Tertiary Care ◽  
Care Facility ◽  
Neck Region ◽  
North India ◽  
Therapeutic Modality ◽  
Treatment Modalities ◽  
Care Hospital

Background: Head and neck neoplasms are the tumours of head and neck region including various subsites in oropharynx, nasopharynx, larynx, upper oesophagus, paranaal sinuses, and ear. Various treatment modalities are available depending on the stage, type, site of tumour. This study was conducted to study the compliance of patients diagnosed with various head and neck neoplasms towards recommended treatment modalities.Methods: 243 patients presenting in the outpatient department of a tertiary care hospital in Northern India with positive biopsy for neoplastic pathology, benign and malignant were included in the study for a period of 2 years (January 2018-December 2019). All the patients were counselled and those who complied with the suggested therapeutic modality were further evaluated.Results: Surgical intervention was carried out in 79 subjects with benign and 133 with malignant pathologies. 49 patients among 133 were advised further surgical intervention. 31 patients underwent second surgery. Radio-therapeutic and chemotherapeutic modalities were undertaken in 66 subjects. 39 patients did not comply with treatment and were lost to follow up.Conclusions: Decision making for head and neck neoplasms is extremely important and should be considered after thorough discussion with the patient.

scholarly journals MICROBIOLOGICAL ASPECT OF FUNGAL RHINOSINUSITIS: STUDY CONDUCTED IN TERTIARY CARE HOSPITAL OF NORTH INDIA.

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Shubhdeep Kaur
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
North India ◽  
Treatment Modalities ◽  
Fungal Culture ◽  
Care Hospital ◽  
Direct Microscopy ◽  
Fungal Rhinosinusitis ◽  
Microbiological Aspect ◽  
Isolated Species

Introduction: Fungal rhinosinusitis is the emerging disease of current era, so isolation of fungus is important aspect to plan the treatment modalities accordingly. Methods: 50 samples of suspected patients of fungal rhinosinusitis were studied. Various samples like nasal secretion, nasal lavage and tissue were examined on direct microscopy using KOH and processed by standard protocols for fungal culture. Result: Out of 50 suspected cases fungal rhinosinusitis was seen in 23 (46%) cases. The 40% of cases were positive by direct microscopy using 20%KOH and 46% were positive by fungal culture. The most common fungal  isolates was Aspergillus flavus (65.5%) followed by  Aspergillus niger (13%). Conclusion: Aspergillus spp. was the most common isolated species among all the cases of fungal rhinosinusitis. Keywords: Aspergillus spp., Fungal, Rhinosinusitis.

Necrotising otitis externa: clinical profile and management protocol

2013 ◽  
Vol 127 (11) ◽  
pp. 1071-1077 ◽  
Author(s):  
D V Lambor ◽  
C P Das ◽  
H C Goel ◽  
M Tiwari ◽  
S D Lambor ◽  
...  
Keyword(s):  
Otitis Externa ◽  
Tertiary Care ◽  
Management Policy ◽  
Treatment Modalities ◽  
Care Hospital ◽  
Third Generation ◽  
Hospital Data ◽  
Management Protocol ◽  
High Index Of Suspicion ◽  
Third Generation Cephalosporins

AbstractBackground:Necrotising otitis externa, which is typically seen in elderly diabetics, is a severe infective disorder caused byPseudomonas aeruginosa. There is lack of standard management policy for necrotising otitis externa, hence this study attempted to frame a protocol for management based on clinical parameters.Method:A retrospective study of 27 patients with necrotising otitis externa was conducted over 6 years in a tertiary care hospital. Data were analysed with regards to demographic characteristics, clinical features, investigations, staging and treatment modalities.Results:Out of 27 patients, 26 were diabetics. The commonest organism isolated wasP aeruginosa, which was sensitive to third generation cephalosporins and fluoroquinolones. Nine patients had cranial nerve involvement. Twelve of 15 patients treated with medical therapy recovered, as did 11 of 12 patients that underwent surgery.Conclusion:A high index of suspicion, early diagnosis and prompt intervention are key factors to decrease morbidity and mortality. Fluoroquinolones, third generation cephalosporins and surgical debridement are the mainstay of treatment.

TO DETERMINE THE ROLE OF CA125 IN THE DIAGNOSIS OF ACUTE APPENDICITIS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta
Keyword(s):  
Acute Appendicitis ◽  
Clinical Diagnosis ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Ca 125 ◽  
Care Hospital ◽  
Serum Samples ◽  
Roc Curve Analysis ◽  
Surgery Department

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.

The Spectrum of Skin Biopsies from a Tertiary Care Hospital in North India

2016 ◽  
Vol 2 (5) ◽  
Author(s):  
Abhilasha Williams ◽  
Anuradha Bhatia ◽  
EmyAbi Thomas ◽  
Clarence J Samuel
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Skin Biopsies

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India (Preprint)

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)

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