scholarly journals Left parathyroid adenoma with features of brown tumor, incidental finding: a case report

2021 ◽  
Vol 8 (12) ◽  
pp. 3705
Author(s):  
Disha Bhandary ◽  
Rithin Suvarna ◽  
Bhaskara Bhandary
Keyword(s):  
Case Report ◽  
Parathyroid Adenoma ◽  
Incidental Finding ◽  
Subtotal Thyroidectomy ◽  
Brown Tumor ◽  
Tumor Excision ◽  
History Of ◽  
Clear Cytoplasm ◽  
Previous Medical History ◽  
Symptomatic Form

Primary hyperparathyroidism (PHPT) occurs in a setting of excessive parathyroid hormone (PTH) secretion with an autonomous parathyroid gland which resulting in hypercalcemia. Cases of parathyroid adenoma are rare, PTH is a chief regulator of calcium homeostasis in the human body. PHPT could be caused by solitary adenomas, hyperplasia, multiple adenomas and carcinomas. A 35-year-old female who came in with complaints of left hip pain past 1 month which aggravated since 1 week, with previous medical history of hyperthyroidism. Laboratory and biochemical findings suggested features of PHPT. She underwent left parathyroid excision with subtotal thyroidectomy. Histopathology analysis revealed features of parathyroid adenoma with eosinophilic to clear cytoplasm, few foci with oxyphilic nodules. Patient showed significant fall in PTH levels after tumor excision and is being discharged 5th day after surgery. PHPT occurs at any age, but it is most commonly seen in people over the age of 50 years and postmenopausal women. The current presentation of PHPT shifts from the classical symptomatic form to the asymptomatic form. parathyroidectomy is still the treatment of choice for both symptomatic and asymptomatic forms. Parathyroid adenoma has an excellent prognosis with surgical treatment.

Giant parathyroid adenoma diagnosed by brown tumor, a clinical manifestation of primary hyperparathyroidism: a case report

2021 ◽  
pp. 1-8
Author(s):  
Banu Yigit ◽  
Mert Tanal ◽  
Bulent Citgez
Keyword(s):  
Case Report ◽  
Primary Hyperparathyroidism ◽  
Secondary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Benign Lesion ◽  
Brown Tumor ◽  
Skeletal System ◽  
Radiological Findings ◽  
Facial Bones ◽  
Osteitis Fibrosa Cystica

Abstract Brown tumor (BT) is the pathological expression of osteitis fibrosa cystica owing to primary and secondary hyperparathyroidism (HPT). It is a rare benign lesion of skeletal system that usually affects the facial bones, clavicles, ribs, pelvis and extremities. The purpose of this case report is to present the clinical, pathological and radiological findings of BT, rarely seen in adults, originating from the giant parathyroid adenoma and emerging as the first clinical sign of HPT. The patient underwent a successful parathyroidectomy operation and on the first postoperative day, the patient was discharged without any complications. Continuous...

scholarly journals Incidental Finding of Posterior Fossa Epidermoid, In a Head Trauma Patient: A Case Report

2019 ◽  
Vol 17 (1) ◽  
pp. 56-57
Author(s):  
Narendra Prasad Baskota ◽  
K. Singh
Keyword(s):  
Case Report ◽  
Head Injury ◽  
Posterior Fossa ◽  
Head Trauma ◽  
Incidental Findings ◽  
Incidental Finding ◽  
Brain Lesions ◽  
Minor Head Trauma ◽  
Post Operative Period ◽  
History Of

Incidental findings of brain lesions in head injury are seen frequently. In our region NCC is common, but in literature meningioma andarachnoid cyst are common. Here we report a case of incidental finding of posterior fossa epidermoid in a 25 years old male patient who had history of minor head trauma which was operated with relatively uneventful post operative period.

Multiple Spinal Cavernous Malformations with Atypical Phenotype after Prior Irradiation: Case Report

Neurosurgery ◽  
2004 ◽  
Vol 55 (6) ◽  
pp. E1435-E1439 ◽  
Author(s):  
Pascal Jabbour ◽  
Judith Gault ◽  
Steven E. Murk ◽  
Issam A. Awad
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Magnetic Resonance ◽  
Wilms Tumor ◽  
Incidental Finding ◽  
Resonance Imaging ◽  
Cavernous Malformations ◽  
Drop Metastasis ◽  
History Of ◽  
Radiation Induced

Abstract OBJECTIVE AND IMPORTANCE: This is the first reported case of histologically proven multiple spinal cavernous malformations (CMs) associated with previous irradiation. There are only two cases reported in the literature of solitary spinal CM after irradiation. In addition, the lesions in our patient had an atypical magnetic resonance imaging appearance mimicking intraspinal drop metastasis. CLINICAL PRESENTATION: A 33-year-old man had an incidental finding of multiple enhancing intraspinal lesions as revealed by magnetic resonance imaging during staging tests for hepatocellular carcinoma. He had a history of Wilms' tumor at a young age with irradiation to the abdomen and pelvis. His family history included a paternal cousin with multiple cerebral CMs. The diagnosis of spinal drop metastasis was made, and further intervention was undertaken for confirmation. INTERVENTION: The patient underwent a lumbar laminectomy with durotomy and excision of two of the lesions. Macroscopic analysis revealed mulberry-like appearance with nerve root involvement, and pathological analysis confirmed the diagnosis of CM. Genetic testing of the patient and his affected cousin was negative for the CCM1 gene. CONCLUSION: The occurrence of multiple spinal lesions in the context of known neoplasia indicates a diagnosis of metastasis. Spinal CMs were not suspected preoperatively because of the atypical appearance revealed by magnetic resonance imaging scans, with uniform contrast enhancement and absence of hemosiderin rim. This case report is discussed relative to previous literature regarding radiation-induced CMs and other known causes of the disease.

scholarly journals Vein of Galen Aneurysmal Malformations: An Ultrasonographic Incidental Finding—A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
S. Stephan ◽  
G. Rodesch ◽  
E. Elolf ◽  
D. Wiemann ◽  
G. Jorch
Keyword(s):  
Case Report ◽  
Incidental Finding ◽  
Transarterial Embolization ◽  
Clinical Signs ◽  
Clinical Results ◽  
Neurological Deficits ◽  
Therapeutic Window ◽  
Vein Of Galen ◽  
Before And After ◽  
History Of

Background. The Vein of Galen aneurysmal malformation (VGAM) is a rare congenital, cerebral, arteriovenous deformity. Good cross-discipline cooperation is in demand because of associated complications and high mortality. The recognition of the optimal therapeutic window is useful to allow proper management.Case Report. We report on the successful treatment of a 2-week-old, healthy girl with a VGAM, which came across in the context of the newborn ultrasonographic screening. After interdisciplinary discussion, 2 embolizations of the VGAM followed without complications—the first in the age of 6 months and the second at 12 months of life. Before and after the intervention, the patient had an age-appropriate development without neurological deficits.Conclusion. The endovascular transarterial embolization is described as the treatment of choice. Time and method of intervention depend on clinical signs of the patient. In our case the patient was asymptomatic. So the arteriovenous abnormality was an incidental finding by ultrasound. Because of the natural history of the disease, and the potential severe neurocognitive consequences at long-term followup if left untreated, it was decided to embolize the lesion. Thanks to embolization with glue, good therapeutical and clinical results could be obtained with normal neurological development.

scholarly journals The case of late diagnosis of giant parathyroid adenoma in combination with fibrocystic osteitis and brown tumor of the upper jaw: a case report

2021 ◽  
Vol 67 (2) ◽  
pp. 49-56
Author(s):  
G. A. Bersenev ◽  
E. A. Ilyicheva ◽  
E. G. Griroryev
Keyword(s):  
Case Report ◽  
Parathyroid Adenoma ◽  
Parathyroid Gland ◽  
Malignant Neoplasm ◽  
Late Diagnosis ◽  
Focal Lesion ◽  
Brown Tumor ◽  
Increased Risk ◽  
Upper Jaw ◽  
The Right

In this case report the authors inform about late diagnosis of giant adenoma of the parathyroid gland with primary hyperparathyroidism (PHPT) and the development of fibrocystic osteitis with a «brown» tumor of the upper jaw. The patient has been under the care endocrinologist with type 2 diabetes mellitus and multinodular goiter for 8 years.The last 5 years there was a clinical manifestation of PHPT, but the diagnosis was made by an oncologist after the detection of a «brown» tumor of the upper jaw. According to multispiral computed tomography and scintigraphy with 99mTc-MIBI, a focal lesion was found in the upper jaw on the right, lytic foci in the bones of the cranial vault, pelvis, lower extremities, ribs on the right, as well as a giant parathyroid adenoma on the right. According to the increased risk of the patient having a malignant neoplasm of the parathyroid gland, an extended surgical treatment of PHPT in the enblock volume was carried out with the achievement of remission of the PHPT. This clinical case illustrates a variant of the severe course of PHPT with the development of such a rare complication as fibrocystic osteitis and demonstrates the importance of timely diagnosis.

scholarly journals Pregnancy-associated atypical haemolytic uraemic syndrome in the postpartum period: a case report and review of the literature

2011 ◽  
Vol 4 (2) ◽  
pp. 83-85 ◽  
Author(s):  
M Egbor ◽  
A Johnson ◽  
F Harris ◽  
D Makanjoula ◽  
H Shehata
Keyword(s):  
Case Report ◽  
Medical History ◽  
Postpartum Period ◽  
Haemolytic Uraemic Syndrome ◽  
Review Of The Literature ◽  
Atypical Haemolytic Uraemic Syndrome ◽  
History Of ◽  
Previous Medical History

Pregnancy has been reported to be a trigger in about 10% of all patients with atypical haemolytic uraemic syndrome (aHUS). However, in contrast to pregnancy-associated thrombotic thrombocytopaenic purpura, the presentation of pregnancy-associated aHUS remains ill defined and can therefore be difficult to diagnose and manage appropriately. Here we report a case of pregnancy-associated relapse of aHUS in a patient with a previous medical history of aHUS prior to pregnancy.

scholarly journals An unusual case of brown tumor of hyperparathyroidism associated with ectopic parathyroid adenoma

2013 ◽  
Vol 07 (04) ◽  
pp. 500-503 ◽  
Author(s):  
Mathan Mohan ◽  
Ravana Sundaram Neelakandan ◽  
D. Siddharth ◽  
Ravi Sharma
Keyword(s):  
Case Report ◽  
Parathyroid Hormone ◽  
Parathyroid Adenoma ◽  
Unusual Case ◽  
Brown Tumor ◽  
Thyroxine Therapy ◽  
Giant Cell Lesion ◽  
Ectopic Parathyroid Adenoma ◽  
Calcium Phosphorus ◽  
Ectopic Parathyroid

ABSTRACTBrown tumor is a giant cell lesion associated with hyperparathyroidism. It is a non-neoplastic condition and represents terminal stage of the remodeling process in hyperparathyroid state. We report a case of brown tumor with multiple lesions in craniofacial region associated with ectopic parathyroid adenoma revealed after acute L-thyroxine poisoning. This case report emphasizes on the need for routine biochemical investigations along with serum calcium, phosphorus and parathyroid hormone levels in patients on thyroxine therapy.

scholarly journals Cherubism - Clinical case report and narrative review

2021 ◽  
Vol 10 (2) ◽  
pp. 22510212085
Author(s):  
Leonardo Alan Delanora ◽  
Ana Maira Pereira Baggio ◽  
Nathália Januario de Araujo ◽  
Idelmo Rangel Garcia-Junior ◽  
Sabrina Ferreira
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Family History ◽  
Bone Disease ◽  
Clinical Characteristics ◽  
Clinical Case ◽  
Giant Cells ◽  
Brown Tumor ◽  
Review Of The Literature ◽  
History Of

Cherubism is described as a rare and benign hereditary bone disease, characterized by a bilateral volumetric increase in the maxillary bones, with a greater predilection for males in childhood. Clinically, it presents as a volumetric enlargement of the mandible and, maxilla, which is generally painless, firm on palpation and varies in relation to size and extension. Its differential diagnosis is the Brown Tumor of Hyperparathyroidism and the Central Lesion of Giant Cells. The diagnosis is based on the assessment of clinical characteristics together with complementary exams. The objective of this study was to carry out a brief review of the literature and report a clinical case of this pathology in a 9-year-old child with a family history of cherubism, assessed through imaging, histopathological and karyotype exams, which continues to be assisted by the oral and maxilofacial surgery team of the Faculdade de Odontologia de Araçatuba - FOA Unesp since the treatment of the cherubism still does not have a definitive protocol.

scholarly journals Congenital vulvar teratoma: a case report

2020 ◽  
Vol 1 (1) ◽  
pp. 5-8
Author(s):  
I Nyoman Hariyasa Sanjaya ◽  
Ryan Saktika Mulyana ◽  
Evert Solomon Pangkahila ◽  
Hartanto Hartanto
Keyword(s):  
Case Report ◽  
Gestational Age ◽  
Rare Event ◽  
Body Parts ◽  
Tumor Excision ◽  
First Line Therapy ◽  
History Of ◽  
Early Tumor ◽  
Unnecessary Complication ◽  
Female Baby

Introduction: Teratoma is an embryonal neoplasm consisted of 3 germinal layers. Teratoma usually arises along the line of embryonic cleft and sinus closure formed by the fusion of skin during the embryonic development. In this case report, we present a case of fetal Teratoma on the vulval region, a very rare variant of the disease. Case: A 28-year-old woman came for a routine check-up for her first pregnancy at her 26th weeks of gestational age. On ultrasound examination, a mass was found around the fetal vulva. There was no mass or malformations on other body parts. Placenta and the amount of amniotic fluid were normal. History of congenital anomaly in the family was denied. The patient then gave birth to a female baby at 38 weeks of gestational age without any complication. The baby was healthy, 2650 gram in weight, 50 cm in length, with good APGAR Score (8-10). On the baby left labia, there was a mass measured 5 cm x 4 cm x 3 cm, with slight discoloration. We recommend an early tumor excision to prevent unnecessary complication such as malignant transformation. Although at the time of writing, the patient still waiting for the schedule to remove the tumor due to a non-medical factor. Conclusion: Congenital Teratoma in the vulvar region was a very rare event. First-line therapy is early tumor excision and usually carries an excellent prognosis.

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