scholarly journals A prospective study of pattern of acute poisoning and treatment outcome in paediatric age group in tertiary care hospital of Konaseema region of Andhra Pradesh, India

2018 ◽  
Vol 5 (2) ◽  
pp. 576
Author(s):  
Katada Narayan Rao ◽  
Payyavula Suresh Babu ◽  
Anand Acharya

Background: Konaseema region of Andhra Pradesh is little different from other area as it is the delta of Godavari river with agriculture and aqua main source of income to the people. This area has mainly rural establishment and no study has been conducted on children to know the pattern of acute poisoning and treatment outcome. Present study has been designed with an aim to study of the pattern of acute poisoning and treatment out come in Konaseema region of Andhra Pradesh.Methods: In present study all the children from birth to 16 years of age who has been admitted in emergency department were recruited. Patients with snake bite, scorpion bites, unknown bites, idiosyncratic reaction to prescribed drugs, food poisoning were excluded from this study. Information were obtained from mother of the patients in most of the cases but father or other guardian were also interview if mother was not available. A pre-designed questionnaire was used for collection of data. This contains demography data of the patient, profile of poisoning, symptoms of the patient presenting with and the outcome of the treatment.Results: Insecticide and pesticides poisoning patients were 122 but of that 60 were organophosphorus, 30 were organochlorines, 10 were carbamates, 20 were rat poisoning and two pts were having herbicides and fungicides poisoning. Fourteen patients were having poisoning by house hold things out of then, four having kerosene oil poisoning, 6 patients having turpentine oil poisoning, two patients with phenyl and rest two patients with KMnO4 poisoning.Conclusions: In Konaseema region pesticides, insecticides and rodenticides are used commonly in agricultural fields and easily available that is the reason for its poisoning in paediatric age group, so awareness about the proper handling of pesticides container and use is required to reduce the incidence.

2017 ◽  
Vol 3 (3) ◽  
pp. 338-343
Author(s):  
Mohammad Didar Khan ◽  
Md. Ibrahim ◽  
Md. Mizanur Rahman Moghal ◽  
Dipti debnath ◽  
Asma Kabir ◽  
...  

Objective: The present epidemiological study was conducted with the objectives of providing an insight into the current use of antidiabetic medications to diabetics and hypertensive diabetics in urban areas and determining how the patient factors influence the prescribing of antidiabetic medications. Methodology: Data of patients of past two years were collected from Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital, Dhaka, Bangladesh. The details were entered in the structured patient profile form. Data were statistically analyzed using the Microsoft Excel 2007 software. Result: A total of 958 patient’s data were collected and analyzed of which 632 (65.97 %) were males and 326 (34.03 %) were females. These patients were further categorized based on their age. 330 patients (34.45 %) belonged to the age group 20 – 44 years, 504 (52.61 %) to the age group 45 – 65 years and 124 (12.94 %) to the age group 65 – 80 years. 684 (71.4%) patients out of the 958 patients studied were suffering from coexisting hypertension. Co-existing hypertension was found to be more prevalent in the age group 45 – 65 years (67.69%) and was found more in females (84.04%). Conclusion: Metformin was the oral hypoglycemic which was the highest prescribed. In hypertensive diabetics Metformin and Pioglitazone were most frequently prescribed drugs. Biguanides and Insulin were the most commonly prescribed antidiabetics. A combination of two or more drugs of different classes was prescribed to hypertensive diabetics. It is necessary to have an improved understanding of the etiology and pathophysiology of diabetes to focus on research efforts appropriately.


2021 ◽  
Vol 15 (2) ◽  
pp. 65-68
Author(s):  
Sharmistha Roy ◽  
Mosammat Mira Pervin ◽  
Mohd Mejbahul Bahar ◽  
Samiron Kumar Mondal ◽  
Md Tariq Hasan

Breast cancer is one of the common cancers in women that causes financial health burden and or death in Bangladesh. Economically we are slowly rising from low to middle income country, which is changing our women's lifestyle. Risk factors of breast cancer include lifestyle factors like- age at first childbirth, parity, using oral contraceptives, BMI; which are also changing in our women. This study will look at our current incidence and patient profile of breast cancer patient. This is a retrospective study done in BIRDEM General Hospital. One hundred patient presenting with breast lump during the period of September 2018 -May 2019 were selected by purposive sampling. In <30 years age group 2 (13.6%) patient had cancer, 41% at <40 years, 53% in 51-60 , 83% in 61-70 age group. Thirty four out of 100 breast lump patient were diagnosed with cancer. Eleven had early cancer, 20 had locally advanced cancer, 3 presented with metastasis. In our study risk factor assessment did not show significant increase risk of in patients who are having cancer compared to those having benign breast disease with similar risk factors. The big number of advance and metastatic breast cancers in our study indicates self-breast examination and breast cancer screening program is still inadequate. Further research is required to find out breast cancer biology and pathogenesis rather than blindly accusing urbanized life style. Faridpur Med. Coll. J. 2020;15(2): 65-68


2021 ◽  
pp. 19-22
Author(s):  
Soumya Gayen ◽  
Bapan Kabiraj ◽  
Jadab Kumar Jana ◽  
Syama Prasad Sit

BACKGROUND: Acute poisoning, a common, yet an important preventable cause of morbidity and mortality in children, is a paediatric emergency globally, responsible for 0.33% to 7.6% of the total paediatric admissions among various hospitals of India. This study was done to assess the changing trends, in the pattern and outcome of poisoning among 1-12 years children. METHODS: This is an institution-based descriptive epidemiological study with cross-sectional design that includes a hundred children of one to twelve years age, conducted over a period of one and half years in the paediatric department of a tertiary care hospital in India. RESULTS: In the study period, majority of the patients out of 100 admitted, were male (65%).Most of those (68%) belonged to the 1-3 years age group. The share of hydrocarbon poisoning (46%) was highest with 26 cases of Kerosene ingestion being the most in it. Important presenting complaints were vomiting, pain abdomen, tachypnoea, and pneumonitis. Only 1 patient died during the course, the cause of which remained unknown. CONCLUSION: The pattern and outcome of acute poisoning in children was quite similar when compared to other studies from different hospitals in India. Survival rates have been increasing due to ongoing improvement in medical infrastructure, which one hopes, shall keep improving along with focus on preventive measures at community levels.


Author(s):  
R. P. Priyadharsini ◽  
R. Kesavan

Background: The usage of antibiotics among paediatric age group in India is on the higher side, that more than 60% of children in the age group 0 to 4 years received antibiotics. The higher use of antibiotics results in antibiotic resistance, increased health care costs, adverse drug reaction and may complicate the treatment of infections in future. There is a continuous need to monitor the prescription of antibiotics at all health care levels to prevent antibiotic resistance.Methods: A prospective and descriptive study was conducted in one of the pharmacies which dispenses the paediatric prescriptions in a tertiary hospital. The prescriptions used to treat infection were collected and analysed. A total of 500 prescriptions were collected and analysed.Results: The prescriptions were analysed for the WHO prescribing indicators. The average number of drugs per prescription is 1.84 with 21% of the prescriptions containing antibiotics. The most commonly prescribed antibiotics were penicillin like amoxycillin, phenoxymethyl penicillin followed by cotrimoxazole and cephalosporin group of antibiotics. The antibiotics prescribed belonged to the access group of antibiotics. The percentage of the prescriptions with drugs form essential drugs list and prescribed with generic name is 65.8% and 67% respectively. There were no injections prescribed.Conclusions: The antibiotic prescribing pattern and the average drugs per prescription falls with the WHO range indicating reduced use of antibiotics and absence of polypharmacy. However, the prescription of generic drugs and the drugs from the essential drug list is less.


Author(s):  
Dr. Sreya Todi

Acute poisoning is common everywhere in medical emergency.  Acute poisoning may be due to deliberate exposure to drugs, chemicals and natural toxins or accidental which is emergency for common medical health.  The main aim of this study was to investigate the pattern of drug utilization, poisoning agents, and outcome in patients with treated acute poisoning. Material and Methods:  This prospective cross sectional study was carried out in the emergency department of a tertiary care centre over a one year period. Result: During the period of 1 year total 310 Acute poisoning cases were recorded by us. Out of 310 acute poisoning cases 170(54.8%) were male where as females were 140(45.2%). The majority of cases were from age group of 20 -50 years in males whereas mean age of female patients was 37.3 years and majority of the cases were from 25-50 age group. The most common route of exposure to poisons (69.6%) was ingestion and followed by dermal exposure (in cases of venomous animal exposures) (25.8%) and inhalation (4.6%).The most common symptomatic treatments given to the patients were antimicrobials (88.7% of cases),  antiemetics (82.6%% of cases), H2 blockers (72.9% of cases) and Atropine (51% of cases), pralidoxime (41.6% of cases)  Proton pump inhibitors and  Vasopressor agents  etc respectively. The most commonly prescribed specific antidotes were Anti-snake venom (ASV) (12.9% of cases).Conclusion: In the present study, the main causes of poisoning were identified as household products in urban areas of India. Awareness about the dangers of such poisons should be the added responsibility of  health and hospital authorities. Poison control center establishment in the region will also help in preventing and controlling such poisoning events.


2021 ◽  
Vol 8 (31) ◽  
pp. 2890-2894
Author(s):  
Vara Prasad Konditi

BACKGROUND Streptococcus pyogenes can affect most often in children with peak age related incidence between 11 to 15 years of age and all races of the world. ASO estimation as an early diagnosis can help to start early & accurate treatment. The objectives of this study were to determine the ASO levels among paediatric age group patients and to estimate the age and sex relation to ASO levels. METHODS A total of 200 patient samples were considered under study population for investigating Anti streptolysin O titres. All the serum samples were processed using Tulip Diagnostics ASO Kits. All blood samples of study population were collected and processed immediately by centrifugation at 3000 rpm for 15 minutes. Serum sample is extracted and processed by semi quantitative method for detection of Anti Streptolysin – O. RESULTS Majority of the patients were observed in the age group of 11 - 15 years i.e., 104 out of 200 (52 %) followed by 5-10 years makes up to 41 %. Male preponderance was noted which accounts for 56.5 % of total cases. Out of 68 male positive patients, 21 (30.8 %) had ASO titres of 200-400 IU / mL, 27 (39.7 %) had ASO titres of 400-800 IU / mL and 20 (29.4 %) had ASO titres of > 800 IU / mL. Out of 31 female ASO positive patients, 5 had (19.2 %) of ASO 200 - 400 IU / mL, 17 had (38.6 %) of ASO 400-800 IU/mL and 9 had (31.03 %) ASO titres of > 8 00 IU / mL. CONCLUSIONS Increase in ASO titres indicate recent infection, which can be tested easily and timely report. Many hospitals are choosing ASO test as a priority investigation to diagnose GAS infections. KEYWORDS Anti-Streptolysin O, Children


Author(s):  
G. R. Vishwanath ◽  
Sandeep Dattatray Babar ◽  
J. D. Naik ◽  
Girish Kamble

Background: Tuberculosis (TB) remains one of the world’s deadliest communicable diseases. In 2013, an estimated 9.0 million people developed TB and 1.5 million died from the disease, 360 000 of whom were HIV-positive. Of the estimated 9 million people who developed TB in 2013, more than half (56%) were in the South-East Asia and Western Pacific Regions and India and China alone accounted for 24% and 11% of total cases, respectively. India’s TB Control Program is on track as far as reduction in disease burden is concerned there was 50% reduction in TB mortality rate by 2013 as compared to 1990 level. Tuberculosis prevalence per lakh population reduced from 465 in year 1990 to 211 in 2013. But still, in India there is high burden of Tuberculosis cases and high mortality in the current situation.Methods: Descriptive Longitudinal study was conducted from 1st January 2015 to 31st December 2016 at designated microscopy centre (DMC) in tertiary care hospital of Government Medical Miraj.Results: Maximum of TB cases 47 (30.71%) were from >30-45 age group and 72 (47.05%) cases belongs nuclear family. 126 (82.35%) cases had completed their treatment schedule for 6/7 months were labelled ‘cured’ at the end of study, while among 27 (17.65%) cases 17 (11.11%) ‘Died’ during treatment schedule, 9 (5.88%) cases became ‘defaulters’ and 1 (0.65%) case was ‘failure’.Conclusions: In the present study, Maximum cases were from >30-45 yrs age group and proportions of males were more as compare to females. Hindus was predominantly more in number among all religions and number of cases coming from rural area was more. The association between gender and treatment outcome of study cases was found statistically significant.


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