scholarly journals Comparison of gestational age assessment by new ballard score and parkin score in neonates

2018 ◽  
Vol 5 (4) ◽  
pp. 1231
Author(s):  
Ravi Ambey ◽  
Priya Gogia ◽  
Arun Kumar M.
Keyword(s):  
Gestational Age ◽  
Analytical Study ◽  
Mean Difference ◽  
P Value ◽  
Strong Positive Correlation ◽  
Age Assessment ◽  
Positive Correlation ◽  
The Mean ◽  
Mean Time ◽  
Normal Neonates

Background: In newborn, both normal and sick, gestational age (GA) is important to evaluate the risks of morbidity and mortality and may modify the line of management. The objective of the present study was to compare the New Ballard Score (NBS) and Parkin’s score in estimating GA among normal neonates, sick neonates.Methods: Observational analytical study of 500 neonates, who qualified the selection criteria. GA estimated by Naegele’s rule (G-LMP), NBS and Parkin score. Data collected and analysed by SPSS 21.Results: The mean gestational age as estimated by last menstrual period was 37.7 weeks; NBS- 37.66 weeks, Parkin score-37.7 weeks. Mean difference between the two scores estimating GA in all neonates was 3.75 days, in normal neonates- 3.61 days, sick neonates-3.7 days. NBS and Parkin score were calculated in both groups, had strong positive correlation (p value <0.05) with G-LMP. GA calculated using NBS and Parkin score had a strong positive correlation (p value <0.05). in all sick neonates except HIE-3 and RDS, NBS had significant correlation with G-LMP, but Parkin score had significant correlation with all. The mean difference between the two scores with RDS and HIE-3 was 11.64 days. Total crying episodes in NBS were 334 and Parkin score were 124. Mean time taken to complete NBS was 5 min 33 sec and Parkin score was 1 min 36 sec.Conclusions: GA of sick neonates with HIE-3 and RDS were better assessed by Parkin score. Parkin score caused less discomfort to neonates.

scholarly journals Placenta thickness: A sonographic index for foetal gestational age estimation

2021 ◽  
Vol 8 (2) ◽  
pp. 217-222
Author(s):  
Faosat O Jinadu ◽  
Adedolapo O Nelson-Paseda ◽  
Tawaqualit A Ottun ◽  
Ayokunle M Olumodeji
Keyword(s):  
Gestational Age ◽  
Linear Regression Analysis ◽  
Study Participant ◽  
Well Being ◽  
Regression Equation ◽  
University Teaching ◽  
P Value ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
The Mean

A healthy placenta is crucial for foetal well-being, growth and development and neonatal survival. Foetal sonographic biometric parameters are crucial in obstetric decision making. This study correlated placenta thickness with foetal biometry in the estimation of gestational age (EGA) and estimated foetal weight (EFW). This was a prospective cross-sectional study in which 400 healthy pregnant women at gestational ages of 13 to 37 weeks, who attended antenatal clinic at the Lagos State University Teaching Hospital, were consecutively recruited. Obstetric ultrasound (USS) was performed to assess placenta thickness (PT), USS EGA and EFW in each study participant. Correlation of these parameters was done using Pearson’s correlation. A regression equation used to assess the relationship between PT and EGA was determined using linear regression analysis at confidence interval of 95% and p-value&#60;0.05. The mean age of the women studied was 30.8±4.8 years. The mean PT ranged from 14.50±0.71 mm at 14 weeks to 36.58±1.54 mm at 37 weeks (wks). There was strong positive correlation between PT and USS EGA (r=0.968, p=0.000). A significant positive correlation was also noted between PT and EFW (r=0.900, p=0.000). There was no correlation between PT and maternal characteristics such as parity(r=-0.015, p=0.772) or maternal age(r=0.018, p=0.720). Ultrasound determined placenta thickness correlated linearly and positively with estimated gestational age and foetal weight. A regression equation of estimated PT was derived as follows; PT(mm) = 1.011 EGA (wks) – 0.663. Ultrasound determined placenta thickness correlates linearly and positively with estimated gestational age and foetal weight.

scholarly journals Evaluation of volume change in oral cavity proper before and after mandibular advancement:

2020 ◽  
Vol 91 (1) ◽  
pp. 81-87
Author(s):  
Balaji Rajkumar ◽  
Ratna Parameswaran ◽  
Anantanarayanan Parameswaran ◽  
Devaki Vijayalakshmi
Keyword(s):  
Oral Cavity ◽  
Statistical Significance ◽  
Mean Difference ◽  
Mandibular Advancement ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
High Statistical Significance ◽  
Proper Volume ◽  
The Mean ◽  
Tongue Volume

ABSTRACT Objectives To evaluate the tongue and oral cavity proper volume in pre- and post-bilateral sagittal split osteotomy (BSSO) patients, and to establish whether there was a correlation between them. Materials and Methods A retrospective study that evaluated 12 patients' pre- and post-surgical computed tomography records satisfying the inclusion criteria. Borders were defined for measurement of tongue and oral cavity proper volume. The volume assessment was carried out using 3D slice software. Results The mean difference of tongue volume was 5.7 ± 1.7 cm3, which showed high statistical significance. The mean difference of oral cavity proper volume (OCVP) was 6.9 ± 3.4 cm3 and indicated high statistical significance. A very strong positive correlation existed between pre- and post-surgical tongue volume. Positive correlation was also evident between pre and post - surgical OCVP. Medium positive correlation was noted when the difference between pre- and post-surgical tongue and OCVP were assessed. Conclusions There was a significant change in volume of tongue and oral cavity proper after BSSO advancement surgery. The space around the tongue, position of tongue, and maxillary and mandibular relationship influence the volume of tongue and oral cavity proper.

scholarly journals INTRA OCULAR PRESSURE

2018 ◽  
Vol 25 (12) ◽  
pp. 1833-1839
Author(s):  
Arsalan Ahmed Rajput ◽  
Azfar Ahmed Mirza ◽  
Ghazi Khan Maree ◽  
Adil Ali Shaikh
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
P Value ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
Intra Ocular Pressure ◽  
Department Of Ophthalmology ◽  
Ocular Pressure ◽  
The Mean

Introduction: The ideal optical properties of the eye requires support of state of the eye-ball which is normally regulated by the intraocular pressure (IOP). There is variation in the measurements of IOP with Goldmann applanation tonometry if the thickness of the central cornea is not uniform, the IOP is high when cornea is thicker and vice versa. Therefore, the central corneal thickness (CCT) is thought to affect the IOP readings, however, as shown, the evidence available remains controversial. The aim of the study was to determine correlation between CCT and IOP. Objectives: To determine the correlation between the Central Corneal Thickness (CCT) and Intra Ocular Pressure (IOP). Study Design: A cross-sectional study. Placeand Duration: Department of Ophthalmology, Aga Khan University Hospital, Karachi from July to December, 2014. Methodology: During the study period of six months total 431 participants were purposively sampled according to the set criteria. Variables included were age, gender, CCT, and IOP. Correlation between IOP and CCT was assessed by using Pearson correlation test, P value of < 0.05 was considered significant. Results: Out of 431 participants, 239 (55.5%) males and 192 (44.5%) females. The mean age was 34.9 ranging from 20 to 50 years. The mean central corneal thickness of right eye was 529 μm with SD ± 39.5 and range of 473-591 μm. The mean intraocular pressure of right eye was 14.7 μm, SD ± 3.1 with a range of 9-21 mmHg. The left eye mean central corneal thickness was 533, SD ± 29.6 with range of 481-589 μm. The mean intraocular pressure of left eye was 15.6, SD ± 3.1 with a range of 10-21 mmHg. Strong positive correlation was found (P-value < 0.001) between central corneal thickness andintra ocular pressure for both eyes. Conclusion: There is positive correlation between CCT and IOP. Therefore, along with the routine ophthalmic examination for intraocular pressure measurements pachymetry should also be considered for accurate interpretation of the results.

scholarly journals FETAL HEAD ANTHROPOMETRY: A CROSSSECTIONAL STUDY FROM KUMAUN REGION

2019 ◽  
Vol 27 (2) ◽  
Author(s):  
Anamika Jaiswal ◽  
Ankit Kaushik ◽  
AK Singh
Keyword(s):  
Gestational Age ◽  
First Trimester ◽  
P Value ◽  
Strong Positive Correlation ◽  
Second Trimester ◽  
Third Trimester ◽  
Fetal Head ◽  
Increase With Increase ◽  
Local Reference ◽  
The Mean

Introduction: Biparietal diameter (BPD) and head circumference (HC) are important for estimating gestational age (GA), monitoring fetal growth and to rule out congenital abnormalities. Western references using HC and BPD can lead to erroneous GA estimation, therefore regional reference is required. Aim: To measure HC and BPD in fetus at different GA, their relationship with GA and comparison of HC and BPD with expected HC and BPD by “Hadlock’s formula”. Material & Methods: CRL, HC and BPD were measured in 72 fetuses. Mean and standard deviation of HC and BPD were calculated for all fetuses and across three trimesters. The correlation of HC and BPD with GA was calculated and p value was derived. Hadlock’s HC and BPD were calculated for the gestational age. The observed HC and BPD in the study were compared with the Hadlock’s value to find out any difference between them Results: The mean HC of fetuses was 23.7 ± 8.58 cm. The mean HC in first trimester was 6.3 cm, 15.13 cm in second trimester and 30.8 cm in third trimester. The mean HC of fetuses according to Hadlock’s formula was 23.72 ± 8.80 cm. The mean Hadlock’s HC in first trimester was 5.6 cm, 14.92 cm in second trimester and 31.12 cm in third trimester. The mean BPD in the studied fetuses was 5.92 ± 2.24 cm. The mean BPD in first trimester was 1.7 cm, 4.8 cm in second trimester and 7.8 cm in third trimester. The mean Hadlock’s BPD was 6.33 ± 2.41 cm. The mean Hadlock’s BPD in first trimester was 1.6 cm, 4.4 cm in second trimester and 8.3 cm in third trimester. The mean HC of fetuses were nearly equal to mean Hadlock’s formula, while BPD of the study fetuses was less than mean Hadlock’s BPD. Both HC and BPD measured at different GA showed increase, with increase in GA and strong positive correlation and statistically significant association. Conclusion: This study had shown that while HC is nearly equal to Hadlock’s reference, BPD was less than Hadlock’s for GA, reflecting need of local reference data for accurate fetal age estimation.

scholarly journals CORRELATION BETWEEN ESTRADIOL SERUM LEVELS WITH XEROSTOMIA INVENTORY SCORE ON MENOPAUSAL WOMEN

2020 ◽  
pp. 122-126
Author(s):  
ISTIA ASRI PARINDA ◽  
MUHAMMAD FIDEL GANIS SIREGAR ◽  
HANUDSE HARTONO ◽  
MAKMUR SITEPU ◽  
INDRA G. MUNTHE ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
General Hospital ◽  
Mean Value ◽  
P Value ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
Menopausal Women ◽  
The Mean ◽  
Xerostomia Inventory ◽  
Estradiol Levels

Objective: Menopause is a condition of permanent cessation of menstruation for 12 consecutive months. This occurs due to the loss of follicular ovarian activity so that estrogen levels decrease in the body. Menopause can occur at various ages, where the average age of menopause is 51-55 y. Menopause can affect oral tissues as well as other organ systems and cause xerostomia. Some of the symptoms of xerostomia include burning feelings, taste abnormalities, dysarthria, dysphagia, dysgeusia, and halitosis. Methods: This study uses a case series design to assess the correlation between estradiol levels and the incidence of xerostomia in menopausal women. The incidence of xerostomia using the Xerostomia Inventory (XI) Score. This research was conducted in several places, namely H. Adam Malik General Hospital Medan and the hospital network of the Department of Obstetrics and Gynecology, Faculty of Medicine, University of Sumatra Utara. The study population was all postmenopausal women at the H. Adam Malik General Hospital in Medan and the Obgyn FK USU network hospital that met the study inclusion-exclusion criteria. This research was conducted in February with a minimum sample of 38 people. Results: In this study, 38 samples were obtained. Based on the results of the study, it was found that the most age groups were in the range of 56-60 y, the duration of menopause in the 5-10 y group, and the highest Body Mass Index (BMI) was obesity. The mean value of estradiol in menopausal women was 23.61±8.37 pg/ml; the mean value of XI score in menopausal women was 24.29±9.44. The correlation of estradiol levels and XI scores in menopausal women is a strong negative correlation that is-0.651 (p value<0.05). Correlation value of XI score and obesity in menopausal women is a low positive correlation with r = 0.342 (p value<0.05) while the value of correlation XI score with menopausal women who are not obese is a strong positive correlation with r = 0.793 (p value<0, 05). Conclusion: Changes in the oral cavity are caused by aging and hypoestrogenism. The mean age of postmenopausal women was 56.98±4.35, with a mean BMI of 28.24±4.41. Estradiol levels in menopausal women are lower than women of reproductive age in each phase of the menstrual cycle. Significant reduction in estrogen production during menopause causes a decrease in salivary flow, leading to hyposalivation and symptoms of xerostomia.

Correlation of AGR2 expression with the incidence of metastasis in luminal breast cancer

2021 ◽  
pp. 1-5
Author(s):  
David Samuel Kereh ◽  
John Pieter ◽  
William Hamdani ◽  
Haryasena Haryasena ◽  
Daniel Sampepajung ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Mean Value ◽  
Rank Test ◽  
Luminal Breast Cancer ◽  
P Value ◽  
Strong Positive Correlation ◽  
Breast Cancer Patients ◽  
The Mean ◽  
Spearman Test

BACKGROUND: AGR2 expression is associated with luminal breast cancer. Overexpression of AGR2 is a predictor of poor prognosis. Several studies have found correlations between AGR2 in disseminated tumor cells (DTCs) in breast cancer patients. OBJECTIVE: This study aims to determine the correlation between anterior Gradient2 (AGR2) expression with the incidence of distant metastases in luminal breast cancer. METHODS: This study was an observational study using a cross-sectional method and was conducted at Wahidin Sudirohusodo Hospital and the network. ELISA methods examine AGR2 expression from blood serum of breast cancer patients. To compare the AGR2 expression in metastatic patients and the non-metastatic patient was tested with Mann Whitney test. The correlation of AGR2 expression and metastasis was tested with the Rank Spearman test. RESULTS: The mean value of AGR2 antibody expression on ELISA in this study was 2.90 ± 1.82 ng/dl, and its cut-off point was 2.1 ng/dl. Based on this cut-off point value, 14 subjects (66.7%) had overexpression of AGR2 serum ELISA, and 7 subjects (33.3%) had not. The mean value AGR2 was significantly higher in metastatic than not metastatic, 3.77 versus 1.76 (p < 0.01). The Spearman rank test obtained a p-value for the 2 tail test of 0.003 (p < 0.05), which showed a significant correlation of both, while the correlation coefficient of 0.612 showed a strong positive correlation of AGR2 overexpression and metastasis. CONCLUSIONS: AGR2 expression is correlated with metastasis in Luminal breast cancer.

scholarly journals Vitamin D Status Among Children aged 2 months to 13 years-a Hospital Based Study

2018 ◽  
Vol 3 (1) ◽  
pp. 381-384
Author(s):  
Hem Sagar Rimal ◽  
Shripad J Walavalkar
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Urban Area ◽  
Serum Calcium ◽  
Winter Season ◽  
College Teaching ◽  
Vitamin D Insufficiency ◽  
P Value ◽  
Strong Positive Correlation ◽  
Positive Correlation

Introduction: Vitamin D is an important micronutrient having crucial role in calcium and phosphate homeostasis but there is emerging evidence to suggest its role in prevention of infectious, inflammatory and neoplastic diseases. The vitamin D insufficiency/deficiency is a widely recognized problem among children in developed as well as developing countries.Objective: To find out the prevalence of vitamin D deficiency/insufficiency among children aged 2 months to 13 yrs and its correlation with serum calcium, phosphate and demographic factors.Methodology: Prospective, cross sectional, hospital based study conducted at Birat Medical College Teaching Hospital for a period of one year among children presented to pediatric OPD in whom pediatrician had a suspicion of Vitamin D Insufficiency /Deficiency. Venous blood Samples were taken for the estimation of 25(OH) Vitamin D, Calcium and Phosphate. Statistical analysis was done using SPSS software version 16. Results Among 174 children aged 2 months to 13 years, the prevalence of vitamin D insufficiency at the cutoff of <30ng/ml was 82.75% where as no cases of vitamin D deficiency was noted at cut off level of < 10 ng/ml. Children residing in urban area, samples taken in the winter season had higher prevalence of vitamin D insufficiency (p value <0.05). Serum calcium and phosphate level were found positively correlated with Vitamin D level (p<.05). However the relationship was very strong between Vitamin D and Calcium (r=0.402, p-value <0.001) and weak positive correlation was noted with phosphate(r=0.155, p value <0.05).Conclusion: There is very high prevalence of Vitamin D insufficiency among children. The vitamin D insufficiency was significantly higher in winter season as compared to summer. Children living in the urban area are more prone to Vitamin D insufficiency. Moderately strong positive correlation was observed between Vitamin D level and calcium but weak correlation existed with phosphate. BJHS 2018;3(1)5 : 381-384

TO COMPARE THE EFFECTIVENESS OF NEBULISATION WITH ADRENALINE, 3% HYPERTONIC SALINE AND NORMAL SALINE IN BRONCHIOLITIS IN CHILDREN OF 2 TO 24 MONTHS OF AGE BASED ON CLINICAL SEVERITY SCORE AND NEBULISATION FREQUENCY.

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Priyanka Jain ◽  
Rakesh Jain
Keyword(s):  
Hypertonic Saline ◽  
Normal Saline ◽  
Mean Difference ◽  
Clinical Severity ◽  
Research Centre ◽  
P Value ◽  
College Hospital ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean

Background & Method: We conducted a double blinded study at Index Medical College Hospital & Research Centre, Indore. The sample size was determined to be minimum of 120 cases as based upon previous years admission due to acute bronchiolitis. Initially, 146 cases were included in the study out of which 23 cases dropped out of the study after giving consent by guardian for participation in the study as they left against medical advice from the hospital. Result: The mean difference of CSS between 0 minutes to 60 minutes of nebulisation between groups in all cases was 0.4 ± 0.6, between 60 minutes and 4 hours was 0.8 ± 0.6, between 4 to 8 hours was 0.7 ± 0.6, between 8-12 hours was 0.6 ± 0.4, between 12-24 hours was 1.6 ± 0.9 and between 24-48 hours was 1.9 ± 0.9.The mean values and resultant p-value of ANOVA of various nebulising agents used for improvement in CSS shows significant association between various nebulising agents used along with improvement in CSS at the end of assessment at 48 hours of treatment. Conclusion: This study was conducted to establish the efficacy of each nebulisation agent (i.e.  adrenaline, 3% hypertonic saline and normal saline) currently used and compare the outcomes as there is not enough evidence amongst Indian population on level of efficacy of each drug in causing improvement in symptoms and signs in various severities of bronchiolitis in early childhood. Comparison of significant improvement in mean difference in CSS at various intervals in all cases compared between groups by post hoc test revealed non-significant difference (p-value 0.700) between 3% hypertonic saline and normal saline. Keywords: nebulisation, adrenaline, bronchiolitis & clinical.

scholarly journals Pengaruh Jus Apel Terhadap Penurunan Tekanan Darah pada Lansia Hipertensi di Puskesmas Muara Kaman

2018 ◽  
Vol 5 (2) ◽  
pp. 121-129
Author(s):  
Siti Khoiroh
Keyword(s):  
Blood Pressure ◽  
Community Health ◽  
Apple Juice ◽  
Antihypertensive Drugs ◽  
Intervention Group ◽  
T Test ◽  
Mean Difference ◽  
Control Group ◽  
P Value ◽  
The Mean

Background : Hypertension is a condition of high blood pressure in the arteries that lasted continuously for the long term. Hypertension can be overcome in two ways: pharmacology and non-pharmacology. Pharmacology treatment usually use medicine while one of the ways for non-pharmacology treatment is to consumes apple juice.Research Objective : The aim of this research is to know the effect of apple juice on blood pressure decrease in elderly people with hypertension at Muara Kaman Community Health Center.Methods : The design of this research used quasi experimental design (quasi experiment) with pretest posttest control group design. The sample of the research was hypertensive respondents at Muara Kaman Community Health Center as many as 30 respondents were divided into 2 groups, 15 intervention groups and 15 control groups. The sampling technique used purposive sampling. The research instruments were stethoscope and sphygmomanometer, data analysis using t test dependent and t test independent.Results : There were a significant influence between pretest and posttest of apple juice in the intervention group (P value = 0,000; P <0.005). The mean difference in systolic blood pressure in the intervention group and the control group also had significant differences (P value = 0.002; P <0.05), where as the mean difference in diastolic blood pressure in the intervention group and the control group also had significant differences (P value = 0,039; P <0,05).The Conclusions : The results of this research showed that consumes apple juice gives an effect on the blood pressure of hypertensive patients by consumes regularly.The Suggestions : Nurses and the public can use apple juice as one of the ways to handling to hypertension sufferers besides antihypertensive drugs.

scholarly journals Estimation of gestational age using foetal kidney length during second and third trimester in south Indian population

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 436-441
Author(s):  
Kalpana Ramachandran ◽  
Arunthathy Gnaneshwar ◽  
Robert Dinesh Kumar ◽  
Parvathavarthine CR ◽  
Sri Santhana Krishnan V
Keyword(s):  
Gestational Age ◽  
Tertiary Care ◽  
Abdominal Circumference ◽  
South Indian Population ◽  
Strong Positive Correlation ◽  
Third Trimester ◽  
Age Assessment ◽  
South Indian ◽  
Kidney Length ◽  
Foetal Kidney

Introduction and Aim: Gestational age assessment in women with indeterminate last menstrual period has always remained an enigma. Though multiple parameters have been found useful in providing an indirect age assessment, various studies have now shown that the ultrasonographic measurement of foetal kidney length during the second and third trimester of pregnancy is a viable alternative in foetal age assessment. Methods: This prospective study was conducted among the antenatal women with singleton uncomplicated pregnancy during 18 to 40 weeks of gestation attending the outpatient department for routine ultrasound foetal biometry in a tertiary care referral institution in South India, during January 2019 to June 2019. A total of hundred and thirty-five antenatal mothers were included in this study. Data entry was done in Microsoft Excel and data analysis was done using Statistical Package for Social Sciences (SPSS). Results: There was a strong positive correlation between GA and MKL. Regression model (Model 1) for Mean kidney length showed significant correlation and regression models (Model 2) for MKL and routine foetal biometric parameters like biparietal diameter, femur length and abdominal circumference were found to be significantly correlated. Conclusion: Mean foetal kidney length can alone predict gestational age and by combining it with the other biometric indices to give a better estimation of gestational age.

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