scholarly journals A study of extra-pulmonary tuberculosis and its outcome

2017 ◽  
Vol 4 (1) ◽  
pp. 209 ◽  
Author(s):  
Ravikumar P. ◽  
Priyadarshini Bai G.
Keyword(s):  
Alcohol Abuse ◽  
Pulmonary Tuberculosis ◽  
Common Site ◽  
Extra Pulmonary Tuberculosis ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Medical College ◽  
Extra Pulmonary ◽  
One Year ◽  
Tuberculosis Disease

Background: Pulmonary tuberculosis being the predominant manifestation of the disease extra-pulmonary sites can also involve as a result of dissemination from a chief focus. Extra- pulmonary tuberculosis is more common in HIV cases. The present study aims to determine the presentation and outcome of patients with extra-pulmonary tuberculosis treated with DOTS and to assess any difference in outcome of treatment in HIV positive extra-pulmonary tuberculosis.Methods: Data was collected from cases of tuberculosis patients diagnosed and treated under DOTS at Sri Siddhartha Medical College for the period of one year (during 2015). We evaluated extra-pulmonary cases and recorded sites of involvement in order of frequency. We also studied treatment outcome by recording as per definitions given by the WHO and also evaluated any difference in outcome of extra-pulmonary tuberculosis disease with HIV co-infection.Results: Extra-pulmonary cases accounted for 30.5% of total TB cases. Among 224 cases of extra-pulmonary TB studied, 136 (60.7%) were males and 88 (39.3%) were females. Most common site of extra-pulmonary tuberculosis was pleura (29.9%) followed by meninges (22.5%), abdomen (19.6%) and lymph node (10.7%) tuberculosis. Among these patients 82.2% completed treatment, 7.5% were defaulted, 9.9% died and 0.4% treatment failure. The most common reason for default was irregular treatment (29.5%) followed by alcohol abuse (23.5%). Among 8 HIV reactive patients, 5 patients completed treatment and the remaining 3 patients died during the course of treatment.Conclusions: Extra-pulmonary Tuberculosis accounts for 30.5% of the total cases studied. Pleura is most common site of extra-pulmonary TB in our study. Treatment irregularities and alcohol abuse are the two most common reasons for default.   Co-infection with HIV seems to have a poor outcome on patients with extra-pulmonary TB and needs to be studied in large number of samples.

scholarly journals Prevalence of Tuberculosis in Diabetic Patients

2021 ◽  
Vol 15 (5) ◽  
pp. 1058-1060
Author(s):  
Shamshad Ali ◽  
M Imran Aslam ◽  
Nayyar M Elahi ◽  
Waseem A Khan ◽  
M Saqib Musharaf ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Extra Pulmonary Tuberculosis ◽  
Medical College ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
The Mean ◽  
Extra Pulmonary

Aim: To determine the frequency of tuberculosis in the patients of diabetes. Study design: Cross-Sectional Place and duration of study: Department of Pulmonology, Avicenna Medical College, Lahore from 1st March 2020 to 31st August 2020. Methodology: Two hundred patients of both genders were presented in this study. Patients detailed demographics age, sex and body mass index were recorded after taking proper consent. Patients admitted in outpatient department with diabetic duration greater than 5years. The different variants of pulmonary and extra pulmonary tuberculosis were measured. Results: There were 120(60%) males and 80(40%) were females with mean age was 51.8±18.22 years. The mean duration of diabetes was 11.5±9.19 years. 60% patients were addicted to gutka and smoking. Active tuberculosis was only found in 30(15%) cases. Pulmonary tuberculosis were 17(56.7%) and the rest 13(43.3%) were extra pulmonary tuberculosis. Eighteen (60%) patients had smear positive and 12(40%) had smear -ve TB. Conclusion: The frequency of tuberculosis in the diabetic patients was high as compared to other population. It can be cure by early diagnosed of disease otherwise multidrug-resistant tuberculosis can become serious health problem among public. Key words: Prevalence, Tuberculosis, Diabetic patient, Multidrug-resistant tuberculosis

scholarly journals Perianal Tuberculosis: A Case Report and a Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
K. Ibn Majdoub Hassani ◽  
S. Ait Laalim ◽  
I. Toughrai ◽  
K. Mazaz
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Pulmonary Tuberculosis ◽  
Review Of The Literature ◽  
Peritoneal Tuberculosis ◽  
Extra Pulmonary Tuberculosis ◽  
Abdominal Organs ◽  
Extra Pulmonary ◽  
Ulcerative Lesions ◽  
One Year

Extra pulmonary tuberculosis accounts for less than 15% of all cases of tuberculosis whereas the Intestinal one constitutes less than 1% of the extrapulmonary forms of the disease. The lesions of abdominal organs are more common while they rarely occur in the anoperineal area for the spread of the disease to the anus is extremely rare. We report a case of a 37-year-old male patient with large bilateral infected perianal tubercular ulcerations as well as pulmonary and peritoneal tuberculosis. The treatment was both surgical and medical and the therapy lasted for seven months. After six months from the beginning of the treatment, the lesion had totally disappeared and there is still no recurrence after one year of followup. Tuberculosis should generally be taken into consideration in the differential diagnosis of the ulcerative lesions of the anal and perianal regions for these lesions do occur in the said areas despite their rarity. The treatment is usually both surgical and medical so as to get excellent results.

scholarly journals SEROPREVALENCE OF HIV INFECTION IN PULMONARY TUBERCULOSIS PATIENTS.

2020 ◽  
pp. 1-3
Author(s):  
K.G.R. Mallan ◽  
A. Fathahudeen ◽  
Manjula V.D.
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Sputum Smear ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Medical College ◽  
Elimination Programme ◽  
Kerala State

Aim : To Determine the seroprevalence of Human immunodeficiency virus infection among Pulmonary Tuberculosis patients in a tertiary care teaching institution, in Ernakulam district of Kerala state in India. Methods : Study was conducted in Respiratory medicine department and integrated counselling and testing centre (ICTC) of Government Medical College, Ernakulam With approval of IEC after getting written informed consent , a cross sectional study was conducted among 384 pulmonary TB patients who were registered under the National TB elimination Programme (RNTCP). Result :The prevalence of HIV among study population was 1.3 %. There was no gender difference while the highest age group less than 30 followed by 30-60. The major respiratory pathology among study subjects was consolidation (42.7%) followed by fibrosis(25.3%).Consolidation was a predominant presenting pathology seen in female pulmonary TB patients.The sensitivity of sputum smear against CBNAAT was 60.4% and specificity was 83%. Conclusion : The prevalence is low compared with the national average of 3 to 3.4 % HIV co infection among Tuberculosis patients during the study period.

Usefulness of GeneXpert MTB/RIF in the diagnosis of extra-pulmonary tuberculosis

2021 ◽  
Vol 11 (2) ◽  
pp. 121-124
Author(s):  
Nasreen Islam ◽  
Mohammad Delwar Hossain ◽  
Muhammad Abdur Rahim ◽  
Jamal Uddin Ahmed ◽  
Muhammad Kamrul Amin ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Pleural Fluid ◽  
Past History ◽  
Gastric Lavage ◽  
Extra Pulmonary Tuberculosis ◽  
Pulmonary Tb ◽  
Male Predominance ◽  
Bacteriological Diagnosis ◽  
Extra Pulmonary ◽  
Tracheal Aspirates

Background: Diagnosis of extra-pulmonary tuberculosis (TB) is often delayed because of diverse clinical presentations and difficulties in establishing the bacteriological diagnosis. This study aimed to evaluate usefulness of GeneXpert MTB/RIF in the diagnosis of extra-pulmonary TB in Bangladeshi patients. Methods: This cross-sectional study was done in BIRDEM General Hospital, Dhaka, Bangladesh from 2013 to 2016 as a part of Bangladesh Diabetic Somiti (BADAS)-USAID-TB Care-II project. Representative samples from 590 clinically suspected extra-pulmonary TB cases were tested for GeneXpert MTB/RIF along with conventional methods. Results: Total patients were 590 [mean age 43.9 (range 1-95) years] with male predominance (326, 55.3%). Most (513, 86.9%) patients were diabetic and new (574, 97.3%) TB suspects; while 16 (2.7%) patients had past history of TB. Common samples were pleural fluid (125, 21.2%), urine (110, 18.6%), cerebrospinal fluid (CSF) (91, 15.4%), pus (82, 13.9%), tracheal aspirates (57, 9.7%), ascitic fluid (45, 7.6%), gastric lavage (31, 5.3%), broncho-alveolar lavage (BAL) (18, 3.1%), lymph node aspirates (11, 1.9%) and synovial fluid (8, 1.4%). Among 590 samples, 68 (11.5%) were positive for Mycobacterium tuberculosis. Diagnostic yield was common for lymph nodes (4/7, 57.1%), pus (25/82, 30.5%), BAL (4/18, 22.2%), tracheal aspirates (8/57, 14.0%), urine (7/110, 6.4%), CSF (6/91, 6.6%) and pleural fluid (7/125, 5.6%). Of the 68 GeneXpert MTB/RIF positive samples, 52 (76.1%) were rifampicin sensitive, 16 (23.9%) showed intermediate sensitivity and none of the samples was resistant to rifampicin. Conclusions: GeneXpert MTB/RIF appeared as useful tool for diagnosing extra-pulmonary TB. Birdem Med J 2021; 11(2): 121-124

scholarly journals Incidence, risk factors and clinical characteristics of extra‐pulmonary tuberculosis patients: a ten‐year study in the North of Iran

2020 ◽  
Vol 25 (9) ◽  
pp. 1131-1139
Author(s):  
Hesamaddin Shirzad‐Aski ◽  
Niloofar Hamidi ◽  
Ahmad Sohrabi ◽  
Abdollah Abbasi ◽  
Roghieh Golsha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
Clinical Characteristics ◽  
Extra Pulmonary Tuberculosis ◽  
Tuberculosis Patients ◽  
The North ◽  
Incidence Risk ◽  
North Of Iran ◽  
Extra Pulmonary
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