scholarly journals Quality of life in gynaecologic cancer subjects attending a tertiary care centre

2017 ◽  
Vol 4 (5) ◽  
pp. 1644
Author(s):  
Ranjini Nanjaiah ◽  
Roopadevi V. ◽  
Mudassir A. Khan
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Demographic Data ◽  
Tertiary Care ◽  
Gynaecological Cancer ◽  
Treatment Modalities ◽  
Median Score ◽  
Significant Difference ◽  
Gynaecologic Cancer

Background: As newer treatment modalities improve survival; quality of life issues takes on increasing importance for survivors. An adequate knowledge is required for psychosocial interventions and designing programs aimed at improving the quality of life of the cancer patients. The purpose of the study is to assess quality of life among gynaecological cancer subjects and its association with duration since diagnosis, type of cancer, mode of treatment and socio-demographic variables.Methods: This is an interview based cross sectional study involving 131 patients diagnosed to have gynaecological cancer who were evaluated using WHOQOL-BREF Questionnaire. The gynaecological and socio-demographic data was analysed for any significant difference in QOL scores using one-way ANOVA.Results: Social domain scored high with median score 50 ± 22.82. Environmental domain scored least with median score 28 ± 24.91. Based on domain scores it was found that only 2.3% subjects had better quality of life. Physical (55.7 ± 7.43) and psychological (57.95 ± 22.85) domain mean score was statistically significantly higher among subjects with cancer for more than 12 months. Subjects who had radiotherapy and chemotherapy scored least (44.52 ± 9.8) and subjects who had surgery and chemotherapy scored highest (59.43 ± 8.8) in physical domain.Conclusions: As cancer incidence is increasing and post treatment survival is improving among cancer patients, two factors are gaining importance. One is early detection and prevention of cancer and the other is improving quality of life of survivors. In clinical practice the QOL instruments may be used with other forms of assessment, giving valuable information that can indicate areas in which a person is most affected and help the practitioner in making the best choices in patient care.

scholarly journals Psychological impact of cancer diagnosis among gynaecological cancer subjects in a tertiary care centre

2017 ◽  
Vol 4 (2) ◽  
pp. 433 ◽  
Author(s):  
Ranjini Nanjaiah ◽  
Mudassir A. Khan ◽  
Vadiraja N. Rao
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Young Women ◽  
Cancer Diagnosis ◽  
Tertiary Care ◽  
Psychiatric Morbidity ◽  
Gynaecological Cancer ◽  
Anxiety And Depression ◽  
Increased Risk

Background: The survival rate of cancer patients has improved and focus has shifted to improve the quality of life of the survivors. An adequate knowledge is required for psychosocial interventions and designing programs aimed at improving the quality of life of the cancer patients. The purpose of the study is to assess Anxiety and Depression [Psychiatric morbidity] among gynaecological cancer subjects and its association with duration since diagnosis, type of cancer, mode of treatment and socio-demographic variables.Methods: This is an interview based cross sectional study involving 131 patients diagnosed to have gynaecological cancer who were evaluated using hospital anxiety and depression scale (HADS). The gynaecological and socio-demographic data was analyzed for any correlation with HADS scores.Results: The prevalence of at least one psychiatric disorder was 90% (n=118). Sixty subjects [45.8%] had anxiety, 71 subjects [54%] had depression and 118 cases [90%] had psychiatric morbidity.  Patients suffering for less than three months had anxiety; three to 12 months were both anxious and depressed; more than 12 months were depressed. Young women with less education were more anxious compared to educated women.Conclusions: Given a gynaecological cancer an individual will have 0.9 chance of developing psychiatric morbidity. Young women with less education aware of cancer diagnosis for three to 12 months were at increased risk and needs intervention. As cancer incidence is increasing and psychiatric morbidity is common among cancer patients, training of health care personnel in cancer screening and recognizing patients with common mental disorders is required to improve their quality of life. Creating awareness of public regarding risk factors of cancers, importance of screening and cancer treatment is necessary.

Role of Erlotinib in Influencing the Quality of Life of Cancer Patients

2020 ◽  
Vol 07 ◽  
Author(s):  
Deepika Purohit ◽  
Parijat Pandey
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Kinase Inhibitors ◽  
Treatment Modalities ◽  
Pancreatic Cancers ◽  
Review Reports ◽  
Causes Of Deaths

Background:: Cancer is one of the significant causes of morbidity and mortality in patients globally. Lung cancer, among other cancers, remains to be one of the principal causes of deaths in both men and women. The most common type of lung cancer is the non-small-cell lung cancer (NSCLC). Apart from lung cancer, pancreatic cancer is also one of the common cancers currently. Objective:: The assessment of QoL in erlotinib-treated patients can also prove to be very useful in the establishment of this drug as the main treatment option for the patients with pancreatic and lung cancer. Methods:: Therapies that target EGFR-mediated signalling are the latest keystones for treating these two types of cancers. They comprise of two main treatment modalities: firstly, against the extracellular fields, that include monoclonal antibodies and secondly, mechanisms that create interferences in the signalling pathways, primarily the small molecule tyrosine kinase inhibitors. Results:: Quality of life (QoL) is one of the key advantages in erlotinib therapy over chemotherapy. Conclusion:: The present review reports the role of erlotinib in improving the quality of life of cancer patients especially in NSCLC and pancreatic cancers. The studies or trials establishing the relations between erlotinib and QoL are discussed in detail in this review.

scholarly journals Quality of life in cancer patients undergoing chemotherapy in a tertiary care center in Malwa region of Punjab

2014 ◽  
Vol 20 (2) ◽  
pp. 116 ◽  
Author(s):  
Harminder Singh ◽  
Kamalpreet Kaur ◽  
RajaParamjeet Singh Banipal ◽  
Shaminder Singh ◽  
Ritu Bala
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center

scholarly journals The Severity of Fatigue Among Bone Marrow Transplantation Patients

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 99s-99s
Author(s):  
O. Abdalrahman ◽  
E. Almashaikh ◽  
H. Aljarrah
Keyword(s):  
Quality Of Life ◽  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Cancer Patients ◽  
Subscale Score ◽  
Medical Intervention ◽  
Significant Difference ◽  
Fatigue Severity ◽  
Male Patients

Background: Fatigue interferes with the individual´s functioning and quality of life in cancer patients specifically, after chemotherapy and post–bone marrow transplantation (BMT), fatigue is not adequately addressed and prioritized among health care providers. Aim: The purpose of this study is to determine the severity and prevalence of fatigue among cancer patients post-BMT after receiving chemotherapy. Methods: A descriptive, cross-sectional and correlational design was used, Piper fatigue scale (PFS) Arabic version was used to measure participants' level of fatigue, the scale measures four dimensions of subjective fatigue: behavioral, affective, sensory, and cognitive. Patients above 18 years old, received chemotherapy and do BMT between Oct 2016 and Oct 2017, were included in this study. Results: 100 patient participated in this study, 52% (N: 52) diagnosed with leukemia, 32% (N: 32) lymphoma, and 16% (N: 16) hematology. Thirty-nine patients (39%) had no or mild fatigue level, they do not need medical intervention, 47% (N: 47) and 14% (N: 14) classified as moderate and sever level of fatigue respectively, equal to 61% of the total sample who need medical intervention. Overall fatigue severity categories; mild, moderate, and sever shows that there is significant difference in term of severity subscale in sensory and behavioral dimensions ( P = 0.03, 0.004) respectively, and the other subscale dimension did not significantly differ among patient ( P > 0.05), the highest mean subscale score occurred in the behavioral dimension (M = 4.8, SD = 2.37), while the lowest mean subscale score occurred in cognitive dimension, (M=2.59, SD=2.35). The overall score mean of the male patients regarding the fatigue severity was 45.18 (n=74), and for the female patients the mean was 57.03 (n=26), and the result shows that there was significant difference in the overall mean scores between male patients and female patients (t (98)= −2.2, P < 0.05). Conclusion: Fatigue-related to BMT is a serious and prevalent problem among patients with cancer. Fatigue may impair quality of life among this group of patients; further study may be conducted to assess the effect of fatigue on quality of life and activity of daily living. It is essential to include fatigue assessment as a priority for the BMT patients.

Complementary therapies in controlling side-effects during cancer treatment

2021 ◽  
Vol 9 (7) ◽  
pp. 238-265
Author(s):  
Vinicius Teixeira Botelho ◽  
MELINE ROSSETTO RODRIGUES ◽  
Guilherme Augusto Rago Ferraz ◽  
Cassiana Mendes Bertoncello Fontes ◽  
Maria Helena Borgato ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Side Effects ◽  
Randomized Clinical Trials ◽  
Care Center ◽  
Tertiary Care ◽  
Risk Of Bias ◽  
Anxiety Control ◽  
Significant Difference

This systematic review evaluated whether reiki had an impact on patients undergoing chemo-therapy, with possible improvement of the following outcomes: fatigue, pain, anxiety and quality of life. Method: Systematic review study with meta-analysis conducted at a tertiary care center. The following databases were searched until July 2020: MEDLINE, LILACS and CENTRAL. Two re-viewers independently examined eligible articles, extracted data and assessed the risk of bias using the Cochrane tool. Results: The analyzes included eight studies and showed that there was a sta-tistically significant for anxiety control (MD = -2-09; 95% CI: -3.00 to -1.19; I2 = 51%) and Quality of life (MD = -5.97; 95% CI: -10.70 to -1.25; I2 = 97%) but no statistically significant difference was found for the other outcomes analyzed. An analysis of the risk of bias has uncertain methodological limitations in the studies. Conclusions: Although there is anxiety control and improved quality of life, there is a need for the elaboration of randomized clinical trials with larger populations to verify their real performance in controlling some side effects during chemotherapy.

Quality of Life and Well-Being of Breast Cancer Patients

2020 ◽  
pp. 67-94
Author(s):  
Melisa Anderson ◽  
Dwayne Tucker ◽  
Fabian G. Miller ◽  
Kurt Vaz ◽  
Lennox Anderson-Jackson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Negative Impact ◽  
Well Being ◽  
Treatment Modalities ◽  
Physical Aspect ◽  
Breast Cancer Patients ◽  
Malignant Breast

Breast cancer is a disease in which there is increased proliferation of malignant breast cells. This disease is more likely to begin in the ducts or lobules rather than the connective tissue. Globally, breast cancer is the most regularly diagnosed cancer. It is also a leading cause of cancer-related mortality in females. While cancer of the breast affects the physical aspect of patients, it can also negatively impact the quality of life (QoL) of survivors. There is a dearth of information, especially in the last decade, on the negative impact of breast cancer and treatment modalities on the QoL of patients. This review of the literature will examine the QoL and well-being of breast cancer patients to present a current perspective on the topic. Major findings of past and present articles that have contributed to improving the care of breast cancer patients will be summarized and included.

Factors affecting health-related quality of life among prostate cancer patients: A systematic review

2020 ◽  
Vol 26 (8) ◽  
pp. 1997-2010
Author(s):  
Sharon Odeo ◽  
Amsalu Degu
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Systematic Review ◽  
Sexual Function ◽  
Cancer Patients ◽  
Clinical Stage ◽  
Treatment Modalities ◽  
Functional Score ◽  
Incidence And Mortality

Introduction Prostate cancer is recognized as the leading cause of malignancy-related incidence and mortality in the male population. The treatment regimens have long-term effects detrimental to the patient's quality of life. Hence, this review was aimed to determine the overall HRQOL and its associated among prostate cancer patients. Methods The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The databases searched were PubMed, Embase, Google Scholar and Cumulative Index to the Nursing and Allied Literature (CINAHL), which provided articles that were critically examined, yielding 52 studies that met the inclusion criteria for the systematic review. Results Out of 52 studies, 30 studies reported poor overall HRQOL in various domains after prostate cancer treatment. Contrastingly, 15 studies reported good overall quality of life after treatment. Among the various domains, sexual function was the most grossly affected functional score by the treatment modalities of prostate cancer. Nonetheless, seven studies showed that the absence of a significant change in the overall quality of life after treatment. According to the studies, older age, comorbidities, higher clinical stage, higher Gleason score, greater cancer severity, African American race, impaired mental health, neoadjuvant hormonal therapy and lower level of education were the major poor predictors of HRQOL among prostate cancer patients. Conclusion The overall HRQOL in prostate cancer patients was generally poor in various functional domains after treatment. Among the various domains, sexual function was the most grossly affected functional score by the treatment modalities of prostate cancer.

scholarly journals Validation of the French version of the Wisconsin Quality of Life (WISQOL) questionnaire for patients with urolithiasis

2020 ◽  
Vol 15 (4) ◽  
Author(s):  
Naeem Bhojani ◽  
Ghizlane Moussaoui ◽  
David-Dan Nguyen ◽  
Mei Juan Trudel ◽  
Garo-Shant Topouzian ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Internal Consistency ◽  
Tertiary Care ◽  
Rank Correlation ◽  
French Version ◽  
Spearman’S Rank Correlation ◽  
Significant Difference ◽  
Back Translation ◽  
One Way Anova

Introduction: The Wisconsin Stone Quality of Life (WISQOL) questionnaire has been recently developed to objectively assess QOL in patients with urolithiasis. However, French version of the questionnaire was lacking. Therefore, the aim of the present study was to develop and validate the French version of this tool. Methods: The French version of the WISQOL (F-WISQOL) was developed in a multi-step process involving primary translation, back-translation and pilot testing amongst a group of patients (n=12). Urolithiasis patients from two tertiary care institutions were recruited into this study and completed 3 questionnaires: Perceived Stress Scale-10, medical history form and either the WISQOL or F-WISQOL. Internal consistency was assessed using Cronbach’s α and inter-domain associations were evaluated using Spearman’s rank correlation (r). One-way ANOVA was used to compare scores from the two groups (WISQOL and F-WISQOL). Results: A total of 210 patients were enrolled in this study; 68 in the WISQOL group and 148 in the F-WISQOL group. Internal consistency was high for all domains in both groups (F-WISQOL: 0.924-0.970; WISQOL: 0.888-0.965). No statistically significant difference was found between the two groups’ scores. Inter-domain association, measured by Spearman correlation, was moderate to very strong between all of the domains in the F-WISQOL. Values ranged from r=0.676-0.915, with acceptable correlation between D1, D2 and D3, but weaker correlation between D4 (vitality) and the 3 other domains r=0.676-0.729. Conclusions: In the present study, the French version of the WISQOL questionnaire (F-WISQOL) was validated at two academic institutions.

The Effect of Prolonged Cycles of Chemotherapy on Quality of Life in Gynaecologic Cancer Patients

1997 ◽  
Vol 23 (2) ◽  
pp. 197-203 ◽  
Author(s):  
Jonathan R. Carter ◽  
M. Dwight Chen ◽  
Jeffrey M. Fowler ◽  
Linda F. Carson ◽  
Leo B. Twiggs
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Gynaecologic Cancer

scholarly journals Older Patients Are Less Affected by Radiochemotherapeutic Treatment than Younger

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Max J. Weiling ◽  
Wencke Losensky ◽  
Katharina Wächter ◽  
Teresa Schilling ◽  
Fabian Frank ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Elderly Patients ◽  
Cancer Patients ◽  
Older Patients ◽  
Normative Data ◽  
Age Groups ◽  
German Population ◽  
Younger Patients ◽  
Significant Difference

Purpose. The general assumption is that cancer therapy impairs the quality of life in elderly patients more than in younger ones. We were interested in the effects of radiochemotherapeutic treatment on the quality of life of elderly patients compared to younger patients and compared to normative data of a general German population. Methods and Materials. A total of 465 patients completed the EORTC QLQ-C30 questionnaire. Repetitive completion of the questionnaire over time led to 1407 datasets. Our patient cohort contained 197 (42.4%) patients with colorectal cancer followed by 109 (23.4%) patients with head and neck cancer, 43 (9.2%) patients with lung cancer, and 116 (25%) with other types of cancer. Patients were categorized into five age groups, the respective cut-offs being 40, 50, 60, and 70 years. Normative data were drawn from a population study of a general German population. Results. Functional scores and symptom scores were approximately stable between the different age groups. Our data does not suggest a significant difference between the investigated age groups. Advancing age evened out the differences between the normative data of the general German population and the cancer patients in 11 of 15 scores. Conclusions. The general belief about younger patients having fewer physical and psychological problems related to radiochemotherapy needs to be reconsidered. Overall resilience of older patients is apparently underestimated.

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