scholarly journals Sensorineural hearing loss and type II diabetes mellitus

Author(s):  
Kavita Sachdeva ◽  
Saima Azim

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">The association between Hearing loss and diabetes, first mentioned by Jardao in 1857, had been under continuous research since then; giving both positive and negative results. This study aims to explore the relationship of hearing loss with type II DM and also to evaluate the impact of glycemic control over degree of hearing loss. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">92 patients with type II DM were enrolled in this study, audiometrically evaluated and compared with equal number of age and sex matched non-diabetic controls. Apart from audiological tests, haematological tests like FBS, PPBS, HbA1c, serum creatinine and cholesterol were carried out to assess glycemic control.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">It was observed that 31 (34%) of the diabetic patients had mild to moderate sensorineural hearing loss, while only 12 (13%) of the control group suffered from the same, which is statistically significant (p&lt;0.05). Among these 31 patients, 19 (61%) patients had uncontrolled diabetes (HbA1c &gt;8.5) and 12 (39%) had higher creatinine levels (&gt;2.5 mg/dl). Higher frequencies (4 and 8 kHz) were found to be affected more, both in case and control groups. Low stapedial reflex thresholds were observed in 14% patients of case group and 5.4% of the controls. Speech discrimination scores were not significantly different. Otoacoustic emission showed outer hair cell dysfunction in 85% cases and 66% controls. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">There is a strong correlation between diabetes mellitus and hearing threshold levels especially at higher frequencies. Long duration and uncontrolled diabetes has more implications over hearing threshold. Since the pattern of hearing loss in diabetes and presbycusis is similar, it may be said that hearing level with ageing is significantly impaired earlier in diabetic patients as compared to general population.</span></p>

2020 ◽  
Vol 162 (3) ◽  
pp. 346-352 ◽  
Author(s):  
Hee Won Seo ◽  
Jae Ho Chung ◽  
Hayoung Byun ◽  
Jin-Hyeok Jeong ◽  
Seung Hwan Lee

Objective The aim of this study was to investigate the clinical implications of diabetes for the management of idiopathic sudden sensorineural hearing loss (ISSNHL). Study Design Retrospective study. Setting Tertiary referral center. Subjects and Methods ISSNHL patients (N = 403) who received inpatient management between January 2015 and December 2018 were analyzed. All were managed by a uniform treatment protocol of high-dose steroid therapy and salvage intratympanic steroid injections. Treatment results were evaluated according to the American Academy of Otolaryngology—Head and Neck Surgery’s criteria 3 months after the start of treatment. We compared the clinical parameters and treatment outcomes of ISSNHL with and without diabetes. We also evaluated the influence of diabetes on the prognosis of ISSNHL by propensity score matching. Results Overall, of the 403 ISSNHL patients, 94 (23.3%) had diabetes, and 11 were newly diagnosed with diabetes. The patients with diabetes were older than those without diabetes ( P < .001), and their initial hearing threshold was significantly higher ( P < .001). The diabetic patients were hospitalized for a longer period, and their hearing recovery rate was lower. However, when age, sex, and initial hearing level were adjusted by propensity score matching, the diabetic patients and matched controls yielded similar treatment results. Conclusions ISSNHL with diabetes usually presents with severe hearing loss and requires longer hospitalization. However, diabetes itself may not influence the prognosis of ISSNHL. Proper management must be provided in ISSNHL with diabetes.


2010 ◽  
Vol 63 (5-6) ◽  
pp. 318-323
Author(s):  
Goran Pudar ◽  
Ljiljana Vlaski ◽  
Danka Filipovic ◽  
Ilija Tanackov

Introduction. Problems of hearing disturbances in persons suffering from diabetes have been attracting great attention for many decades. Material and methods. In this study we examined the auditory function of 50 patients suffering from diabetes mellitus type 1 of different duration by analyzing results of pure-tone audiometry and brainstem audi?tory evoked potentials. The obtained results of measuring were compared to 30 healthy subjects from the corresponding age and gender group. The group of diabetic patients was divided according to the disease duration (I group 0-5 years; II group 6-10 years, III group over 10 years). Results and discussion. A statistically significant increase of sensorineural hearing loss was found in the diabetics according to the duration of their disease (I group = 14.09%, II group = 21.39%, III group = 104.89%). The results of the brain stem auditory evoked potentials, the significance threshold being p=0.05 between the controls and the diabetics at all levels of absolute latency of right and left sides, did not show significant differences in the mean values. In the case of interwave latencies, the diabetic patients were found to have a significant qualitative difference of intervals I-III and I-V on both ears in the sense of internal distribution of response. In cases of sensorineural hearing loss we found a significant connection with prolonged latencies of I wave on the right ear and of I and V waves on the left ear. In all probability, the cause of these results could be found in distinctive individuality of the organism reactions to the consequences of this disease (disturbance in the distal part of n. cochlearis). Conclusion. The results of research have shown the existence of a significant sensorineural hearing loss in the patients with diabetes mellitus type 1 in accordance to the disease duration. We also found qualitative changes of brainstem auditory evoked potentials in the diabetic patients in comparison to the controls as well as significant quantitative changes in regard to the presence of sensorineural hearing loss of the patients.


1979 ◽  
Vol 44 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Irving Shapiro

The relationship between hearing level and loudness discomfort level (LDL) for narrow-band noise was evaluated in two groups of patients with sensorineural hearing loss. Group I had thresholds ranging from 25–60 dB SPL and Group II’s thresholds ranged from 65–100 dB SPL. LDLs were determined for narrow bands of noise centered at 500, 1000, 2000, and 4000 Hz. The LDLs for Group II were greater than those for Group I and the differences were statistically significant. It is speculated that one reason for others not finding differences as a function of hearing level may be the absence of severe to profound hearing loss in the test populations.


2020 ◽  
Vol 15 (1) ◽  
pp. 884-889
Author(s):  
İbrahim Özcan ◽  
İbrahim Hira ◽  
Altan Kaya ◽  
Mehmet Yaşar ◽  
Murat Doğan ◽  
...  

AbstractBackgroundWe aimed to evaluate the association between mean platelet volume, platelet distribution width (PDW), platelet count (PC) and plateletcrit (PCT), and the presence of sudden sensorineural hearing loss (SSNHL) and treatment response. In the literature, there is no study that investigates the platelet functions in diabetic patients with SSNHL.MethodsThe patients were retrospectively assigned into Group 1 (68 diabetic patients with SSNHL), Group 2 (63 nondiabetic patients with SSNHL) and Group 3 (64 healthy controls).ResultsPC was not significantly different between the groups (p > 0.05). MPV, PDW and PCT values were significantly higher in Group 1 as compared to Groups 2 and 3 (p < 0.05). Platelet parameters were not significantly different between the patients who were responsive and nonresponsive to the treatment. Therefore, the platelet parameters did not affect prognosis significantly in this study samples (p > 0.05).ConclusionsThis study showed that platelet parameters did not have a significant effect as a prognostic and predictive value in diabetic and nondiabetic patients with SSNHL. Further studies with more homogenous and larger study groups investigating the platelet parameters are needed to demonstrate microvascular damage and vascular alterations induced by diabetes mellitus.


Author(s):  
Dhivya K ◽  
Yogarajan K ◽  
Shanmugarajan T S

ABSTRACTObjective: Periodontitis, a chronic inflammatory disease characterized by destruction of the periodontal ligament and alveolar bone is the sixthcomplication of diabetes mellitus. Periodontal treatment that reduces gingival inflammation aids in the control of hyperglycemia. Therefore, thepresent study was designed to determine the effect of treating chronic periodontitis with oral antibiotics azithromycin and metronidazole on the levelof serum glycated hemoglobin in type-II diabetic patients.Methods: This prospective observational study was carried out in the dental department of a tertiary care hospital for 9 months. Clinical andbiochemistry reports of 90 patients were collected in designed case report forms. All statistical analyses were performed using IBM Statistical Packagefor Social Sciences 17 and Graph Pad Prism 7.0.Results: Significant reduction in all the clinical and dental parameters was comparatively higher in patients who received azithromycin than inpatients who received metronidazole and scaling and root planning alone.Conclusion: Periodontal therapy with oral azithromycin can be employed as a supportive strategy for the management of diabetes mellitus.Henceforth, prevention and control of periodontal disease along with antibiotics must be considered an integral part of glycemic control. However,due to the lesser sample size in this study, further investigations are required to confirm the effect of periodontal therapy on systemic diseases.Keywords: Periodontitis, Azithromycin, Metronidazole, Glycemic control, Diabetes mellitus.


2008 ◽  
Vol 136 (5-6) ◽  
pp. 221-225
Author(s):  
Slobodan Spremo ◽  
Zdenko Stupar

INTRODUCTION Cochlear damage secondary to exposure to acoustic trauma is the consequence of the acoustic energy effects on the hearing cells in Korti's organ. OBJECTIVE The objective was to assess the correlation between the degree of sensorineural hearing loss and the type of audiogram registered in acoustic trauma exposed patients. METHOD We analyzed 262 audiograms of patients exposed to acoustic trauma in correlation to 146 audiograms of patients with cochlear damage and hearing loss not related to acoustic trauma. "A" group consisted of acoustic trauma cases, while "B" group incorporated cases with hearing loss secondary to cochlear ischaemia or degeneration. All audiograms were subdivided with regard to the mean hearing loss into three groups: mild (21-40 dB HL), moderate (41-60 dB HL) and severe (over 60 dB HL) hearing loss. Based on audiogram configuration five types of audiogram were defined: type 1 flat; type 2 hearing threshold slope at 2 kHz, type 3 hearing threshold slope at 4 kHz; type 4 hearing threshold notch at 2 kHz; type 5 notch at 4 kHz. RESULTS Mild hearing loss was recorded in 163 (62.2%) ears in the acoustic trauma group, while in 78 (29.8%) ears we established moderate hearing loss with the maximum threshold shift at frequencies ranging from 4 kHz to 8 kHz. The least frequent was profound hearing loss, obtained in 21 (8%) audiograms in the acoustic trauma group. Characteristic audiogram configurations in the acoustic trauma patient group were: type 1 (N=66; 25.2%), type 2 (N=71; 27.1%), and type 3 (N=68; 25.9%). Audiogram configurations were significanly different in the acoustic trauma group in comparison to the cochlear ischaemia group of patients (p=0.0005). CONCLUSION Cochlear damage concomitant to acoustic trauma could be assessed by the audiogram configuration. Preserved hearing acuity at low and mild frequency range indicates the limited damage to the hearing cells in Korti's organ in the apical cochlear turn.


2021 ◽  
Vol 29 (2) ◽  
pp. 182-188
Author(s):  
Deepika Goswami ◽  
Saurabh Srivastava ◽  
Anuja Bhargava ◽  
Syed M Faiz ◽  
Zeba Siddiqi ◽  
...  

Introduction Diabetes has become a global epidemic. Hearing loss has been long associated with diabetes. Brainstem Evoked Response Audiometry (BERA) is an objective, non-invasive, electro diagnostic test that not only evaluates the functional integrity of the subcortical auditory pathway but also provides topo-diagnosis of hearing loss. This study aims to identify the role BERA in detecting hearing loss early in diabetic patients.Materials and Methods In this study a total of 210 patients were taken and subjected to blood glucose levels followed by PTA were divided into two groups. Group I (n=105) consisted of diabetic patients with sensorineural hearing loss (SNHL) and Group II (n=105) had age and sex matched non-diabetics with SNHL. All the patients were evaluated with BERA.Results All the patients were subjected to Brain Stem Evoked Response Audiometry (BERA). Absolute latency of Wave I, III, V, I-III, III-V and I-V were assessed for both the ears. In both ear Absolute latency were significantly higher in diabetics as compared to non-diabetic patientsConclusion The findings of present study showed that the severity of hearing loss was significantly higher in diabetic patients as compared to non-diabetic controls. Level of glycemic control showed a possible link with severity of hearing loss.


2019 ◽  
Vol 1 (1) ◽  
pp. 32-36
Author(s):  
Shahid Majeed ◽  
Nazia Mumtaz ◽  
Ghulam Saqulain

Background: Diabetes Mellitus (DM) is a common metabolic disorder with a prevalence of 11.77%. Studies report that DM can result in Sensorineural hearing loss (SNHL). A high prevalence of Hearing loss (HL) (43.6%) in diabetics was noted in an Indian study. In absence of local studies and a high expected prevalence, with no screening recommendations, this study was carried out to determine the prevalence of Sensorineural Hearing Loss (SNHL) in Diabetes Mellitus DM in Southern Punjab. Methodology: In this cross-sectional study, a sample of 310 diabetics, hailing from southern Punjab and fulfilling selection criteria were recruited. Samples were collected using probability sampling technique from September 2016 to December 2016. Following detailed history and examination, cases were subjected to pure tone audiometry (PTA) at 0.5 to 6 KHz to obtain hearing thresholds to determine the prevalence. Data was analyzed by SPSS 20. Results: Sample included N=310 diabetics with Mean age of 35.00 + 6.93 years with 58.39% males and 41.61% females. The prevalence of HL was 46.1%. Gender wise of the male population with HL, 27.97% and 28.67% had mild and moderate HL respectively with severe HL in 8.39% cases, while moderate HL was prevalent in females 20.98%, followed by mild HL in 9.97% and severe HL in 4.20%. There was significant correlation between Diabetes and SNHL with p-value < 0.05. Conclusion: There is a high prevalence of sensorineural hearing loss in Diabetes mellitus.


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