scholarly journals Evaluation of antibiotic sensitivity pattern in acute tonsillitis

2018 ◽  
Vol 4 (5) ◽  
pp. 1162
Author(s):  
Mayur H. Ingale ◽  
G. D. Mahajan
Keyword(s):  
Antibiotic Sensitivity ◽  
Microbial Pathogens ◽  
Research Centre ◽  
Resistance Pattern ◽  
Acute Tonsillitis ◽  
College Hospital ◽  
Medical College ◽  
Drug Of Choice ◽  
Institutional Ethics ◽  
Sensitivity Pattern

<p class="abstract"><strong>Background:</strong> The use of antibiotics against different pathogens in acute tonsillitis has been the general trend through the years. Penicillin has been the drug of choice for the management. But due to increased incidence of resistance in case of penicillin’s, other antibiotics are also used for the treatment of acute tonsillitis. The study was conducted with the objective to find out the antibiotic sensitivity and susceptibility pattern against microbial pathogens in acute tonsillitis.</p><p class="abstract"><strong>Methods:</strong> Our prospective observational study was carried out in the otorhinolaryngology department in Dr. D. Y. Patil Medical College, Hospital and Research Centre. The period of study was from June 2015 to August 2015. After getting approval from the Institutional Ethics Committee (IEC) throat swabs were collected randomly from 50 patients visiting the ENT OPD. An informed consent was obtained from every patient who was a part of this study before commencing the study.  </p><p class="abstract"><strong>Results:</strong> The commonly used antibiotics showed a higher resistance pattern as compared to the less commonly used antibiotics. Ampicillin and Amoxicillin showed poor sensitivity results in case of both <em>Streptococci </em>as well as <em>Staphylococci</em>.</p><p><strong>Conclusions:</strong> Study findings therefore helped in perusing a guarded and judicious use of antibiotics in cases of acute tonsillitis and will thus help in improving the quality of antibiotic therapy provided to the patient. </p>

scholarly journals Prevalent Bacteria and Their Sensitivity and Resistance Pattern to Antibiotics: A Study in Dhaka Medical College Hospital

2017 ◽  
Vol 26 (1) ◽  
pp. 52-64
Author(s):  
Mohammad Zaid Hossain ◽  
Akhtarun Naher ◽  
Pratyay Hasan ◽  
Kazi Tuba E Mozazfia ◽  
Homyra Tasnim ◽  
...  
Keyword(s):  
Nalidixic Acid ◽  
Antibiotic Sensitivity ◽  
Sampling Technique ◽  
Salmonella Typhi ◽  
Medical College Hospital ◽  
Resistance Pattern ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Changes Over Time

Background and rationale: Antibiotic resistance is a global problem. Many factors are complexly related to the issue in multiple dimensions. Bangladesh is right in the middle of this great calamity, and is seeing the rise in resistant strains of several bacteria. Very sadly, the prevalent malpractice of abusing antibiotics in Bangladesh contributes to add complexity to the danger which may prove to be possibly the greatest threat humans have ever faced. There is much scarcity of medical literature in Bangladesh, on the antibiotic sensitivity pattern and prevalent microorganisms. Moreover, antibiotic sensitivity pattern changes over time and place. Again, most of the studies done in Bangladesh, concentrate on a single disease, pathogen, or specimen. This study attempts to see the prevalent microorganisms and the antibiotic sensitivity pattern in multiple types of specimens collected from Dhaka Medical College Hospital. This study also attempts to establish a way of presentation of the relevant findings which can be used in future to ensure easy comparability and contrasting of findings.Methods: The specimens were collected from the adult patients (age >12 years) admitted in the Internal Medicine ward of Dhaka Medical College Hospital, Dhaka, over a period of 6 months. The sampling technique was consecutive sampling method. Specimens which were culture positive, were only included in the study for analysis. Multiple specimens were taken.Results: S. aureus was 100% sensitive to amikacin, moxifloxacin, imipenem, meropenem, piperacillin+tazobactum combination, vancomycin, doxycycline, tetracycline, tigecycline, nitrofurantoin, azactum, linezolid and 100% resistant to cefixime. Enterobacter was 100% sensitive to penicillin, amikacin, gentamicin, netilmicin, doxycycline, tetracycline, tigecycline and 100% resistant to cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, levofloxacin, vancomycin. E. coli was 100% sensitive to imipenem, meropenem, vancomycin, tigecycline and 100% resistant to mecillinam, aztreonam. Klebsiella was 100% sensitive to flucloxacillin, colistin, vancomycin, tigecycline, linezolid and 100% resistant to nalidixic acid. Proteus was 100% sensitive to cephradine, cefoxitin, cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, amikacin, ciprofloxacin, imipenem, meropenem, netilmicin, piperacillin+tazobactum combination, tetracycline, tigecycline, azithromycin, azactum and 100% resistant to doxycycline, tetracycline, chloramphenicol and cefuroxime. Pseudomonas was 100% sensitive only to amikacin, netilmicin, and 100% resistant to cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, gentamicin, ciprofloxacin, levofloxacin, imipenem, meropenem, doxycline, tetracycline, chloramphenicol. Salmonella typhi was 100% sensitive to amoxicillin, cefoxitin, cefixime, ceftriaxone, cefepime, cotrimoxazole, amikacin, netilmicin, azithromycin, chloramphenicol, azactum and 100% resistant to cephradine, doxycycline, tetracycline, nalidixic acid. MRSA was 100% sensitive to imipenem, vancomycin, teicoplanin, nitrofurantoin, linezolid and 100% resistant to cefpirome, cefoxitin, ceftazidime, cotrimoxazole, clindamycin, gentamicin, ciprofloxacin, netilmicin, tetracycline, clarithromycin. Acinetobacter was 100% sensitive to penicillin, cefuroxime, colistin, piperacillin+tazobactum combination, tigecycline, chloramphenicol and 100% resistant to cefixime, nalidixic acid. Citrobacter freundii was 100% sensitive to ceftazidime, ceftriaxone, cotrimoxazole, amikacin, gentamicin, ciprofloxacin, levofloxacin, imipenem, meropenem, netilmicin, nalidixic acid and 100% resistant to ampicillin, cefixime, nitrofurantoin.Conclusion: More and more antibiotics are becoming ineffective due to emergence of resistance. Serious actions should be taken. Awareness should be raised from the policy maker level to the physicians and patients.J Dhaka Medical College, Vol. 26, No.1, April, 2017, Page 52-64

Antibiotic Sensitivity and Resistance Patterns of Salmonella Typhi in Rajshahi Medical College Hospital

2020 ◽  
Vol 33 (2) ◽  
pp. 10-14
Author(s):  
Md Azizul Haque ◽  
Laila Shamima Sharmin ◽  
KM Faisal Alam ◽  
Md Mohimanul Hoque ◽  
M Morsed Zaman Miah ◽  
...  
Keyword(s):  
Blood Culture ◽  
Enteric Fever ◽  
Antibiotic Sensitivity ◽  
Salmonella Typhi ◽  
Medical College Hospital ◽  
Personal Hygiene ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern

Typhoid and paratyphoid fevers, collectively known as enteric fever, is caused by Salmonella enterica subspecies serovars Typhi and Paratyphi A, B and C. Despite this declining global trend, enteric fever is still considered to be a major public health hazard in Bangladesh and other developing countries due to poor sanitation, inadequate food safety measures and poor personal hygiene. In Bangladesh, the incidence of typhoid fever was reported to be 200 episodes per 100,000 person-years during 2003–2004. Multidrug-resistant (resistance to the first-line antimicrobials ampicillin, cotrimoxazole, and chloramphenicol) strains of S. Typhi and S. Paratyphi are on the rise globally and even cases of extensively drug-resistant (XDR) typhoid cases resistant to chloramphenicol, ampicillin, trimethoprim-sulfamethoxazole, third generation cephalosporins and fluoroquinolones are being reported from many corners of the world. This descriptive, observational study was carried out in Rajshahi Medical College Hospital Hospital, Rajshahi, Bangladesh from July 2017 to June 2019. Antibiotic sensitivity pattern of total 76 cases of enteric fever due to Salmonella Typhi were studied. Blood culture was carried out by BACT ALERT-3D, Automated blood culture analyzer from BioMeriuex SA, France Patented FAN Plus method. Based on the minimum inhibitory concentration (MIC), the organism was categorized as sensitive, intermediate, and resistant against the respective antibiotics as per Clinical and Laboratory Standards Institute (CLSI) criteria. We are reporting antibiotic sensitivity and resistant patterns of S. Typhi documented in Rajshahi Medical College Hospital, a large tertiary care hospital in Northern Bangladesh. TAJ 2020; 33(2): 10-14

scholarly journals Blood Culture Isolates and Antibiogram of Salmonella: The Gathering Storm

KYAMC Journal ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 188-190
Author(s):  
Ishrat Binte Reza ◽  
HAM Nazmul Ahasan ◽  
Moshtaque Ahmed ◽  
Homayra Tahseen ◽  
Tasmina Chowdhury
Keyword(s):  
Drug Resistance ◽  
Antibiotic Sensitivity ◽  
Multidrug Resistant ◽  
Bacterial Strains ◽  
College Hospital ◽  
Major Health ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Highly Sensitive ◽  
The World

Introduction: Typhoid fever is a common problem all over the world including Bangladesh. It is caused by salmonella typhae and paratyphae and it is an old infectious water born disease. It is encountered in Bangladesh throughout the year. For many years it is treated by Chloramphenicol and subsequently Cotrimoxazole and Amoxicillin. Despite the use of newly developed antibacterial drugs, enteric fevers caused by multidrug-resistant bacterial strains are one of major health problems in Bangladesh. Multidrug resistant Salmonella sp. has been emerged is a cause of concern. Materials and Methods: This is a retrospective study done at the Popular Medical College Hospital over a period of 6 months between January 2018 to june 2018. Results: During the study period, total 115 cases were enrolled. Regarding antibiotic sensitivity pattern, 69% strains were sensitive to Ampicillin, 100% to Cefixime and Ceftriaxone, 75% to Cotrimoxazole, 52% to Nalidixic Acid and 68% to Ciprofloxacin, 69% to Levofloxacin, 80% to Cholarphenicol. Conclusion: Ceftriaxone and Cefixime were found to be highly sensitive. So, we should be very careful for the judicious use of these valuable drug to prevent drug resistance. KYAMC Journal Vol. 10, No.-4, January 2020, Page 188-190

Bacteriological Profiles of Pus with Antimicrobial Sensitivity Pattern at a Teaching Hospital in Dhaka City

2018 ◽  
Vol 5 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Rashida Akter Khanam ◽  
Md Rafiqul Islam ◽  
Ahmed Sharif ◽  
Rezina Parveen ◽  
Ishrat Sharmin ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Burn Injuries ◽  
Microbial Pathogens ◽  
College Hospital ◽  
Medical College ◽  
Aerobic Culture ◽  
Antimicrobial Sensitivity ◽  
Cellular Debris ◽  
Sensitivity Pattern ◽  
Antibiotic Susceptibility Test

Background: The human skin and soft tissue infections (SSTIs) caused by microbial pathogens during or after trauma, burn injuries, and surgical procedures result in the production of pus, a white to yellow fluid comprised of dead WBCs, cellular debris, and necrotic tissues.Objective: The purpose of the present study was to see the frequency and distribution of bacteria isolated from pus and sensitivity pattern.Methodology: This retrospective study was conducted in the Department of Microbiology at Shaheed Suhrawardy Medical College, Dhaka from January 2016 to December 2016 for a period of one (01) year. The pus samples were collected from the patients who were visited in outpatient department and were admitted at IPD in Shaheed Suhrawardy Medical College Hospital (ShSMCH), Dhaka with skin and soft tissue infection. Bacteria were detected by culture and biochemical test and antibiotic susceptibility test done by disc diffusion method.Result: A total number of 212 patients presented with wound infection or pus were recruited for this study. Among 212 patients majority were in the age group of 20 to 40 years which was 89(42.0%) cases. Interestingly male was predominant than female which was 119(56.1%) cases and 93(43.9%) cases respectively. aerobic culture was positive in majority cases which were 131(61.8%) cases.Conclusion: In conclusion the most common isolated bacteria after aerobic culture of pus is the Staphylococcus aureus. However the gram positive cocci is less in number than gram negative bacilli.Bangladesh Journal of Infectious Diseases 2018;5(1):10-14

scholarly journals Antibiotic Sensitivity Pattern in Neck Space infection

2020 ◽  
Vol 19 (2) ◽  
pp. 28-31
Author(s):  
Md Mukhlesur Rahman ◽  
Mahmuda Begum ◽  
Md Mujibul Hoque Khan ◽  
Mostafa Mahfuzul Anwar
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Agents ◽  
Antibiotic Sensitivity ◽  
Neck Surgery ◽  
College Hospital ◽  
Klebsiella Species ◽  
Medical College ◽  
Space Infection ◽  
Sensitivity Pattern ◽  
Life Threatening

Background: Infection caused by microorganisms are common and may be serious and life threatening, requires immediate attention and management to get best outcome. The purpose of this study is to assess the anatomical spaces and causative microorganisms responsible for neck infections and evaluate the sensitivity pattern of the isolated microorganisms to antimicrobial agents. Materials and methods: This study was carried out in the Department of Otolaryngology- Head and Neck Surgery, Chittagong Medical College Hospital, from January to December 2018. A total of 70 cases were selected consecutively. All underwent surgical incision & drainage. Pus sample was obtained either by aspiration or by swab stick from the involved spaces and culture and sensitivity tests were performed. Results: The most common neck space infection were submandibular abscess 27 (38.57%) followed by Ludwig's angina 20 (28.57%). Out of 70 cases, 51(72.86%) cases yielded positive growth and 19(27.14%) cases showed no growth. Predominant microorganisms were Staphylococcus aureus, Streptococcuspyogenes, klebsiellaspecies and E coli. Staphylococcus aureus showed sensitivity to vancomycin, clindamycin, gentamycin. Streptococcus pyogenes showed sensitivity to cefuroxime, ceftriaxone and klebsiella species showed sensitivity to amikacin. Conclusion: Bacteriological examination and culture help to identify the causative microorganisms in neck abscess. It helps to isolate even the rarest of the organism and by knowing there sensitivity pattern, we can direct specific therapy against them. It thus helps in a more effective treatment and fast recovery of patients. Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 28-31

scholarly journals Pattern of antibiotic sensitivity of bacteria causing urinary tract infection in a private medical college hospital in Dhaka

2015 ◽  
Vol 14 (1) ◽  
pp. 70-74
Author(s):  
Shahin Sultana ◽  
Marium Khatun ◽  
Md Khoybar Ali ◽  
Nurunnahar Mawla ◽  
Nayareen Akhter
Keyword(s):  
Urinary Tract ◽  
Medical Science ◽  
Antibiotic Sensitivity ◽  
Urine Samples ◽  
Resistance Pattern ◽  
Medical College ◽  
Frequency Rate ◽  
Sensitivity Pattern ◽  
Tract Infections ◽  
Culture Positive

Background: Urinary tract infections (UTI), being the most common infections diagnosed in community and hospital, are to be treated scrupulously considering the type of infecting organism and its antibiotic sensitivity and resistance pattern. Aims and objectives: The aim of the present study was to observe the antibiotic sensitivity pattern of isolated uropathogens from urine samples of patients attending at Shahabuddin Medical College & Hospital, Dhaka, during the period of July 2008 to June 2009. Result: A total of 555 urine samples were studied; of which 84 (15.13%) were culture positive. Among 84 culture positive cases, 84 isolates were identified. Among the isolates, E.coli was the most predominant 61 (62.88%) followed by Enterococci 11 (11.34%), proteus 4 (4.13%) and Pseudomonas 3 (3.09%). Whereas Staphylococcus saprophyticus and Klebsiella showed frequency rate of 2 (2.06%) for each. However Gram positive cocci showed lowest frequency rate of 1 (1.03%). All of the isolates were sensitive to Netilmicin. The majority of isolates were sensitive to Imipenam (92.3%) followed by Amikacin (91.1%), Meropenam (83.3 %), Tetracycline (70%). Sensitivity & resistance rate were same (50%) in Vancomycin & Cefodoxime. Where complete (100%) resistance was shown to Ampicillin, Azithromycin and Cefoxitin. However all isolates were poorly sensitive to cotrimoxazole (35.7%), ciprofloxacin (43%) and nitrofurantoin (44.8%). Conclusion: So, routine urine culture and susceptibility before therapy should be encouraged and periodic evaluation of predominant organisms and their antimicrobial susceptibility pattern should be studied for appropriate selection of antibiotic for effective management of UTI cases.DOI: http://dx.doi.org/10.3329/bjms.v14i1.21562 Bangladesh Journal of Medical Science Vol.14(1) 2015 p.70-74

scholarly journals Detection and Antibiotic Sensitivity Pattern of Gardnerella vaginalis Isolated from Bacterial Vaginosis Patients Attending Chittagong Medical College Hospital

2017 ◽  
Vol 16 (1) ◽  
pp. 48-53
Author(s):  
Nura Nasrin Rowshan Ara ◽  
Md Anwar Husain ◽  
Nasima Akter ◽  
Shakeel Ahmed ◽  
Md Mostafizur Rahman ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Prospective Observational Study ◽  
Antibiotic Sensitivity ◽  
Medical College Hospital ◽  
Gardnerella Vaginalis ◽  
Sexually Active ◽  
College Hospital ◽  
Medical College ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern

Background: Now a day’s bacterial vaginosis is an extremely common health problem for women in the world which causes many complications both in the pregnancy and non-pregnancy states. G. vaginalis is most important cause of bacterial vaginosis.Methods: A prospective observational study was conducted to detect G. vaginalis in bacterial vaginosis and their sensitivity patterns on patients attending at the outpatient Department of Gynaecology and Obstetrics of Chittagong Medical College Hospital, Chittagong. A total of 170 sexually active female in the age group of 15-45 years, with abnormal vaginal discharge were selected for the study. A detailed history and a thorough clinical examination of all the cases were done.Results:In this study 38(22.35%) Gardnerella vaginalis were isolated by culture and bacterial vaginosis was detected by different methods 47(27.65%). Antimicrobial resistance is one of the major public health threats. So antimicrobial sensitivity pattern of the organisms should be done at regular intervals.Conclusion: In this study Gardnerella vaginalis showed high (52.63%) resistant to most commonly used metronidazole and 100% sensitive to clindamycin.Chatt Maa Shi Hosp Med Coll J; Vol.16 (1); Jan 2017; Page 48-53

scholarly journals Antimicrobial Resistance Situation in SCANU of Faridpur Medical College Hospital, a Tertiary Level Hospital in Bangladesh

2020 ◽  
Vol 15 (1) ◽  
pp. 28-33
Author(s):  
Abu Faisal Md Pervez ◽  
Kyu Han Lee ◽  
Farzana Islam ◽  
Md Kamrul Hassan ◽  
Rajib Biswas
Keyword(s):  
Antimicrobial Resistance ◽  
Neonatal Sepsis ◽  
Local Level ◽  
Venous Blood ◽  
Antibiotic Sensitivity ◽  
Medical College Hospital ◽  
Resistance Pattern ◽  
Coagulase Negative Staphylococci ◽  
College Hospital ◽  
Medical College

Considering the high risk of neonatal sepsis in low and middle-income countries, empirical antibiotic therapy is commonly employed in most cases to clinically suspected septic neonates without the aid of culture and antibiotic sensitivity report. Increasing antimicrobial resistance is posing a threat to these practices and urges the obligation for understanding the causative organisms and their changing resistance pattern at the local level. Aim of this study was to identify the pathogens responsible for neonatal sepsis and understand their current antimicrobial resistance pattern. This prospective study was undertaken in the Special Care Newborn Unit of the Faridpur Medical College Hospital from October 2017 to November 2018. Venous blood culture and antimicrobial susceptibility of 56 suspected neonatal sepsis cases were studied. Among the 56 clinically suspected cases 86% had culture positive isolates in the specimen. Predominant isolates were Klebsiella (42%) and coagulase-negative staphylococci (25%). Of all the identified bacteria, 88% were resistant to >_ 3 classes of antibiotics. Eighty-five percent of Klebsiella isolates were found to be carbapenem-resistant along with 100% of E. coli isolates and 95% of Klebsiella isolates had possible extended spectrum b -lactamase production. Seventy-five percent of Acinetobacter isolates were multidrug-resistant and 100% of coagulase-negative staphylococci were methicillin resistant. The array of causative organisms and their increasing resistance to commonly practiced antibiotics are alarming. It is urgent to develop strategies focusing on all healthcare levels to cease the spread of antimicrobial resistance in an effort to reduce the burden of neonatal sepsis. Faridpur Med. Coll. J. Jan 2020;15(1): 28-33

scholarly journals Study of Various Organisms Associated with Surgical Site Infection and their Sensitivity Pattern

2015 ◽  
Vol 2 (2) ◽  
pp. 118 ◽  
Author(s):  
Hemant Borse ◽  
Rahul Shelke
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Sensitivity ◽  
Resistance Pattern ◽  
Site Infection ◽  
Health Care Centre ◽  
E Coli ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Subject Material ◽  
Micro Organisms

<strong>Aim</strong>: The objectives of this study was to study the various micro-organisms causing surgical site infection, to study their antibiotic sensitivity and resistance pattern. <strong>Setting</strong>: Department of Surgery of a tertiary health care centre with an attached medical college. <strong>Material and methods</strong>: A total of 89 patients with post operative surgical site infection occurring within 30 days of surgery or 1 year of implant were included as subject material after they satisfy inclusion and exclusion criteria. <strong>Results</strong>: <em>E.coli</em> is the commonest organism isolated in SSI wounds. Overall Imipenem and Amikacin are the most sensitive antibiotics. Over all gentamycin, cefotaxime and clindamycin are the most resistant antibiotics noted. <strong>Conclusion</strong>: The most common organisms associated with SSI are <em>E. coli</em> and Pseudomonas. Most of the organisms were sensitive to imipenem, amikacin. Sensitivity pattern of the of the organism is changing with time. The common organisms are now no longer sensitive to routinely used cheaper antibiotics. Newer antibiotics, which are more costly, are required to treat the infection which is a burden to the patient.

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