scholarly journals Clinical spectrum of facial hypermelanosis: a descriptive study from a tertiary care centre

2020 ◽  
Vol 6 (2) ◽  
pp. 212
Author(s):  
Mohammed Thoyyib ◽  
Roshni Menon ◽  
Brinda G. David
Keyword(s):  
Tertiary Care ◽  
Clinical History ◽  
Climatic Conditions ◽  
Research Centre ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Pigmentary Disorders ◽  
Number Of Patients ◽  
The Face ◽  
Detailed Clinical History

<p class="abstract"><strong>Background:</strong> Facial melanosis (FM) which refers to brown, black or blue pigmentation over the face is a common cosmetic concern in Indian patients. This increased incidence could be due to remarkable diversity of Indian ethinic population. Pigmentary disorders of the face are a great cosmetic and psychological concern for the patients.</p><p class="abstract"><strong>Methods:</strong> This is an extensive descriptive clinico epidemiological study comprising of 1024 patients, conducted at Sri Venkateshwara Medical College Hospital and Research Centre, Puducherry, for a period of one and a half years. A detailed clinical history and examination was done, and all the clinical photographs and data were recorded. Necessary investigations like skin biopsy and patch testing was done wherever required.<strong></strong></p><p class="abstract"><strong>Results:</strong> The maximum number of patients belong to the age group of 21-35 years with a female predominance (67.2%). Among patients of FM, post inflammatory pigmentation (35.3%) was the most common comprising of 362 patients, followed by melasma (17.2%), periorbital melanosis (15.7%), seborrheic melanosis (7.5%) followed by other causes.</p><p><strong>Conclusions:</strong> FM is common in Indian skin, several of which have overlapping features, and some have defined clinical classification. Additionally, climatic conditions, cosmetic usage and social parameters predispose to the increased incidence of FM.</p>

scholarly journals Clinical features & outcome of dengue cases at a tertiary care centre

2021 ◽  
Vol 53 (1-2) ◽  
pp. 3-7
Author(s):  
Md Nazrul Islam ◽  
Sabikun Nahar Chowdhury ◽  
SK Moazzem Hossain ◽  
Arina Shorani Mousi
Keyword(s):  
Tertiary Care ◽  
Public Health Problem ◽  
Clinical History ◽  
Complete Recovery ◽  
Medical College Hospital ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Medical College ◽  
Atypical Manifestations ◽  
Detailed Clinical History

Background: Dengue is a very common seasonal public health problem causing significant mortality every year. In 2019 an outbreak occurred in Bangladesh. Few new manifestations and multi organ involvement were found. Objective: The objective of the study was to see the clinical and laboratory manifestations and outcome of dengue fever in a medical college hospital. Methods: It was an observational study in a medical college hospital in Bangladesh. Study period was one year. The patients were confirmed cases of dengue. Apart from detailed clinical history, examination of patient, relevant investigations and follow up was done until discharge. Result: Total number of cases was 98. Out of them 62 (63.2%) were male and 36 (36.73%) were female. Fever was most common (100%) manifestation and duration of fever ranged from 5 to 8 days with a mean duration of 6.3 (± 1.0) days. Among other symptoms generalized body ache was most common (63, 64.3%). Generalized weakness was present in 60 cases (61.2% cases) Bleeding manifestations was present in 41 cases; abdominal manifestations were found in 11 cases. Blood for NSI was positive in 94 (95.9%) cases; most cases (71, 72.4%) became positive between 2nd to 4th day. Ninety (91.9%) cases developed thrombocylopcnia and it started at 5th day in 45 (45.9%) cases. Blood transfusion was given in 12 (12.2%) cases & Platelet transfusion was given in 3 (3.1%) cases. Complete recovery was in 96 (98%) cases and Death occurred in 2 (2.0%) cases. Conclusion: Bleeding was a dominant presentation. Some atypical manifestations like gastro intestinal features were also observed. These findings will help physicians in early diagnosis of dengue. Bang Med J Khulna 2020: 53 : 3-7

scholarly journals Assessment of developmental outcome of neonatal seizures at NICU of tertiary care centre hospital

2016 ◽  
Vol 4 (1) ◽  
pp. 100
Author(s):  
Swati Saral ◽  
Pawan Ghanghoria
Keyword(s):  
Tertiary Care ◽  
Preterm Neonates ◽  
Developmental Outcome ◽  
Neonatal Seizures ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Face To Face ◽  
Medical College ◽  
The Face ◽  
Centre Hospital

Background: Seizures are relatively common among first month of life. New-born with neonatal seizures are at risk of developmental delay. The objective of this study was to assess the developmental outcome of neonatal seizures and to study the factors associated with delayed developmental outcome in neonatal seizures.Methods: A prospective observational Study was conducted in 71 term and preterm neonates with documented seizure admitted in Medical college hospital, Jabalpur. A predesigned pretested questionnaire was used. The face to face interview technique was used for collection of data by mother, followed by clinical examination of newborn and investigations were done. DDST II was used for developmental assessment of neonates. Results: Neonates with delayed developmental outcome are 42.62%. Delayed developmental outcome is significantly associated with male sex, low birth weight, prematurity and multiple frequencies of seizures.Conclusions: The delayed developmental outcome was high among neonatal seizures. 

scholarly journals Childhood cardiomyopathies: a study in tertiary care hospital of Kashmir

2021 ◽  
Vol 8 (2) ◽  
pp. 289
Author(s):  
Abid Ahmad Shairgojri ◽  
Khalid Mohiuddin ◽  
Amber Bashir ◽  
Muzafar Jan
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Dilated Cardiomyopathy ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Clinical History ◽  
Left Ventricular ◽  
Care Hospital ◽  
Medical College ◽  
Number Of Patients ◽  
Detailed Clinical History

Background: Cardiomyopathy constitutes a group of diseases that directly affect the structural or functional ability of myocardium. They are the most common form of heart diseases that are inherited in children and responsible for sudden deaths in healthy young adults. The Aim of our study was to provide a detailed description of clinical profile, epidemiology and etiology of cardiomyopathies in children.Methods: This was a hospital based prospective observational study, conducted over a period of two and half years from September 2017 to March 2020 in the Post Graduate Department of Pediatrics Government Medical College Srinagar. Study group included all patients aged between 1 month and 18 years diagnosed with cardiomyopathy. They were subjected to a detailed clinical history and physical examination. All the patients underwent echocardiography.Results: During the study period 37 patients were diagnosed with different types of cardiomyopathies. Dilated cardiomyopathy was commonest seen in 19 (51.35%), followed by hypertrophic cardiomyopathy 13 (35%) cases. Fast breathing was most common presenting complaint in dilated cardiomyopathy while most of cases with hypertrophic cardiomyopathy were asymptomatic. There was one case of distinct form of cardiomyopathy isolated left ventricular hypoplasia. Males were more involved 21 (56.76%) cases. Majority of patients 18 (48.64%) were less than one year at time of diagnosis. Parental consanguity was seen in 6 (16.22%) cases. Underlying cause was identified in 10 (27.02%) cases with myocarditis being the commonest cause.Conclusions: Pediatric cardiomyopathy represents a considerable percentage of children with cardiac disorders. Dilated cardiomyopathy is the most common type usually presented with congestive heart failure, majority of cases of hypertrophic CMP were asymptomatic. Male preponderance was seen in dilated and hypertrophic cardiomyopathy. Parental consanguinity was seen in significant number of patients. Myocarditis and inborn error of metabolism was seen in significant number of patients.

scholarly journals A CLINICAL STUDY OF PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA

2017 ◽  
Vol 10 (7) ◽  
pp. 373 ◽  
Author(s):  
Karthik Rao ◽  
Gurukanth Rao ◽  
Navin Patil ◽  
Balaji Ommurugan ◽  
N R Rao ◽  
...  
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Tertiary Care ◽  
Clinical History ◽  
Sustained Remission ◽  
Care Hospital ◽  
College Hospital ◽  
Thrombocytopenic Purpura ◽  
Medical College ◽  
Immune Globulins ◽  
Detailed Clinical History

OBJECTIVE To study the incidence, age and sex distribution among adults, various modes of presentation, correlation between thrombocytopenia and bleeding manifestations and various modalities of treatment of Idiopathic Thrombocytopenic Purpura in a tertiary care hospital in India.MATERIALS AND METHODSProspective study consisting of 4o cases of ITP admitted to Kasturba Medical College Hospital, Manipal from November 2005 to March 2007. Patients above 14 years of age admitted with thrombocytopenia in this institution were screened based on detailed clinical history, physical examination and laboratory investigations.RESULTSThe maximum incidence was in the 3 rd decade of life accounting for 27.5% of the patients. Ratio of male to female was 1:1.9 with female preponderance. Females in 3 rd decade had maximum incidence while males in 4th decade have maximum incidence. Majority 12 (85.71%) of male patients and 15(57.69%) of female patients  developed purpura during the course of disease. The mean count was 17.8X109/L with range between 2.0 X109/L to 76 X109/L. Cutaneous bleeding spots were found to be assosiated with counts above 25000X109/L and hematuria with lowest counts around 4000 X109/L. 20 (50%) of the above 40 patients responded to corticposteroids alone and did not have any further relapse. Among the remaining patients 3 (7.5%) had a relapse of symptoms within next 6 months and responded to repeat prednisolone started at 1mg/kg. 2 (5%) patients were given steroids tapering dose with IV Immune globulins for initial 5 days as therapy to which they responded.CONCLUSIONIdiopathic thrombocytopenia is 1.9 times more common in females than males. Most common presentation is bleeding spots over body. Bleeding manifestations are more common with thrombocytopenia less than 30000/mm3. Corticosteroids are the mainstay in treatment. Complete remission is seen in up to 57.5% of the patients. Splenectomy is the second modality of treatment in ITP. Complete and sustained remission is seen 75% of patients.  

scholarly journals Prevalence of adenomyosis and associated gynaecological pathologies in hysterectomy samples: a retrospective study

2021 ◽  
Author(s):  
Lekshminath Gopinath ◽  
Rajani Vaidya
Keyword(s):  
Tertiary Care ◽  
Abnormal Uterine Bleeding ◽  
Serous Cystadenoma ◽  
Uterine Bleeding ◽  
Research Centre ◽  
Common Symptom ◽  
Age Group ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Case Record

Background: Adenomyosis is a prevalent gynaecological disorder among women and it is a major cause for AUB. Its diagnosis is confirmed by histological examination of hysterectomized samples. Moreover it is associated with other benign gynaecological pathologies. The aim of this study is to identify the prevalence of Adenomyosis and its association with other benign gynaec pathologies in hysterectomized samples.Methods: This retrospective of two year duration was conducted in obstetrics and Gynaecology department of Malabar Medical College Hospital and Research Centre, a tertiary care centre in Kozhikode, Kerala from 2019 June to 2021 June. 452 patients underwent hysterectomy for abnormal uterine bleeding during this period. Among this, 76 patients had histologically proven adenomyosis in hysterectomy specimen and their case record were reviewed and the data was analysed.Results: The prevalence of Adenomyosis in this study was 16.8%. Majority of women were in age group of 41 to 46 (36.8%), followed by 46 to 50 age group (26.3%). 94 % of women were multipara with majority in para2 and para3 group. Only 6 % of women were nulliparous. Most common symptom was abnormal uterine bleeding (92%), followed by dysmenorrhoea and chronic pelvic pain. Majority had overlap of symptoms. 7% of women were asymptomatic. In 60 % of women no other gynaec pathologies were identified. Most common associated pathology was leiomyoma (15.8%), closely followed by endometriosis (13.2%). Endometrial hyperplasia was associated with adenomyosis in 3.9%of women and endometrial polyp in 2.6%. Ovarian pathologies identified were simple ovarian cyst (2.6%) and serous cystadenoma (1.3%).Conclusions: In the present study, the prevalence of adenomyosis was high and abnormal uterine bleeding was the patients’ most prevalent complaint. Among the associated gynaec pathologies, leiomyoma had the highest correlation with adenomyosis.

scholarly journals Prevalence of oral mucosal lesions in a tertiary care centre: one-year prospective study

2020 ◽  
Vol 6 (9) ◽  
pp. 1704
Author(s):  
Smruti Milan Tripathy ◽  
Poonji Gupta ◽  
Akshay Jain ◽  
Probal Chatterji
Keyword(s):  
Oral Cavity ◽  
Early Stage ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Research Centre ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Number Of Patients ◽  
Malignant Lesions ◽  
One Year

<p class="abstract"><strong>Background:</strong> Lesions of the oral cavity are very common among the general population and account for a significant number of patients in the outpatient department of otorhinolaryngology. The lesions of oral cavity can cause varied symptoms like pain, dysphagia, and difficulty in speaking. The lesions can range from simple benign conditions to life threatening malignancies.</p><p class="abstract"><strong>Methods:</strong> This study was conducted in the department of otorhinolaryngology, Teerthanker Mahaveer Medical College and Research Centre from January 2019 till December 2019. All the 256 patients who presented to the outpatient department with lesions in the oral cavity during the given time period were included in the study after getting informed and written consent.  </p><p class="abstract"><strong>Results:</strong> Aphthous ulcers were the most common lesion (18.7%) found in this study. Buccal mucosa (50%) and anterior 2/3<sup>rd</sup> of tongue (34.3%) were the most common sites involved. Total of 204/256 (79.6%) patient had some form of addiction which included both smoked and smokeless form of tobacco as the most common type of addiction. Among the tobacco smokers, 24/80 (30%) had pre malignant and malignant lesions while among tobacco chewers 37/76 (48.6%) had pre malignant and malignant lesions.</p><p class="abstract"><strong>Conclusions:</strong> Lesions of the oral cavity are common among Indian population due to high prevalence of tobacco addiction. A thorough history taking and examination can detect premalignant and malignant lesions at an early stage, so that timely treatment can reduce the mortality rates in such patients.</p>

scholarly journals Clinico-hematological evaluation in cases of pancytopenia at tertiary care centre: largest cross-sectional study

2021 ◽  
Vol 9 (5) ◽  
pp. 1361
Author(s):  
Haridas S. Munde ◽  
Nitin Y. Shende ◽  
Swati D. Nagare
Keyword(s):  
Bone Marrow ◽  
Tertiary Care ◽  
Clinical History ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Bone Marrow Morphology ◽  
Detailed Clinical History ◽  
Hematological Evaluation

Background:  Pancytopenia is characterised by a reduction in all the three cellular elements of blood (erythrocytes, leukocytes and platelets) below the normal reference range leading to anaemia, leucopenia and thrombocytopenia. It is a feature of many serious conditions. The present study was conducted to assess aetiology, clinical profile and bone marrow morphology of conditions presenting with pancytopenia.Methods: A two years cross-sectional study from July 2017 to June 2019 was conducted in the Department of Pathology. Total of 300 pancytopenia patient were studied and their clinical features, peripheral smear finding and bone marrow morphology were studied by using marrow aspiration and biopsy.Results: Among 300 cases studied, maximum patients were in the age group 11-20 years (19.66%) with male (50.66%) predominance. Most of the patients presented with weakness (91.66%) and fever (56.66%) as chief complains. The commonest physical finding was pallor (94%) followed by splenomegaly (27.33%). Macrocytic anaemia (43.66%) was commonest peripheral finding. The commonest cause of pancytopenia was megaloblastic anaemia (32.66%) followed by dimorphic anaemia (21%), aplastic anaemia (16%) and acute leukaemia (13.33%).Conclusions: The present study concludes that detailed clinical history, primary haematological investigations along with bone marrow examinations is essential to determine the cause of pancytopenia.

scholarly journals Profile of epileptic patients at a tertiary care centre

2020 ◽  
Vol 8 (7) ◽  
pp. 2547
Author(s):  
Kushel Verma ◽  
Dinesh Dutt Sharma ◽  
R. C. Sharma
Keyword(s):  
Tertiary Care ◽  
Clinical History ◽  
North India ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
General Physical Examination ◽  
Generalized Seizures ◽  
Detailed Clinical History ◽  
Gandhi Medical College ◽  
General Physical

Background: The present study was done in a tertiary care centre of North India to know the profile of epilepsy.Methods: Total of 210 patients were selected during the period August, 2017 to July 2018 who attended outpatient clinic of the Department of Neurology, Indira Gandhi Medical College, Shimla, Himachal Pradesh. Detailed clinical history was taken, general physical examination, and routine blood examination were carried out.Results: Of all the cases, sex ratio (male:female) was 2.39:1. A high proportion of cases (43.3%) were from lower-middle socio-economic group. 76.7% patients had generalized seizures. For 38.6% patients, frequency of seizures was more than 8 in the past 6 months. 71.9% of the patients were using only one anti-epileptic drug.Conclusions: Patients with seizures comprise a significant burden in inpatient department of developing countries.

CLINICOPATHOLOGICAL PROFILE OF BREAST LESIONS AT TERTIARY CARE CENTRE.

2021 ◽  
pp. 64-66
Author(s):  
S.K. Nema ◽  
Ritika Bharti
Keyword(s):  
Tertiary Care ◽  
Malignant Lesion ◽  
Research Centre ◽  
Breast Lesions ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Duct Carcinoma ◽  
Molecular Features ◽  
Study Results

Background: Breast tissue is a modied sweat gland. Breast lesions present with variety of pathological lesions, ranging from inammatory, non- inammatory, non- neoplastic and neoplastic lesions. Breast carcinoma is multifaceted disease comprised of distinct biological subtypes spectrum of clinicopathological, molecular features and different therapeutic and prognostic implications. The present study was designed to evaluate the frequency, age, gender and histopathological features of breast lesions in a tertiary care hospital. Material and Method: The study was conducted in department of pathology, Index medical college hospital & Research centre,Indore. We retrieved breast specimen received in histopathology department over a period of 24 months from June 2018 to June 2020. A total of 106 cases of breast lesions were included in the study. Results: Out of a total of 106 cases of breast lesions, most common lesions were benign 56 (52.83%) with mean age 30.15 years, followed by malignant 50(47.16%) with mean age 48.16 years . The overall mean age of patients was 40.46 years, with a wide age of 11–88 years. Overall the most commonly reported lesion was broadenoma 35 (33.01%) cases, followed by inltrating duct carcinoma 50 (47.16%) cases, mastitis 3(2.8%) cases, Galactocele 3(2.8%) cases. The maximum cases of malignancy were seen in age group more than 40 years of age of life. Most common malignant lesion was inltrating duct carcinoma. Conclusion: The breast lesions pattern revealed by the present study provides valuable information regarding clinicopathological prole of breast lesions.

scholarly journals Magnitude, risk factors and outcome of low birth weight babies admitted to neonatal intensive care unit of a tertiary care centre in Puducherry, India

2020 ◽  
Vol 7 (6) ◽  
pp. 1389
Author(s):  
Maheswari K. ◽  
Neha Sharma
Keyword(s):  
Risk Factors ◽  
Teenage Pregnancy ◽  
Tertiary Care ◽  
Research Centre ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Maternal Risk ◽  
Feeding Difficulties ◽  
Preterm Babies ◽  
Pregnancy Avoidance

Background: This study was undertaken to know the magnitude, risk factors and outcome of LBW babies admitted in NICU in a tertiary centre.Methods: This is a hospital based, retrospective study, of LBW babies admitted to NICU of Sri Venkateshwara Medical College hospital and research centre, Puducherry, from Jan 2019 - Dec 2019.Results: About 340 babies were admitted to NICU and 56 were LBW babies, 5 were excluded and 51 LBW babies analysed. Magnitude of LBW babies, 51 (15%). Socio demographic pattern showed, IUGR (62.7%). Term IUGR (52%) and preterm IUGR (9.8%). Preterm babies (37.2%). Preterms <28 weeks of gestation (7.8%), 28-34 weeks (9.8%) and 34 to < 37 weeks (19.6%). LBW babies <1kg (7.8%), 1-1.5kg (1.9%) and 1.5 to 2.49 kg (90.1%). Male (52.9%), female babies (47%). LBW babies from rural area (62.7%), urban area (37.2%). Among the maternal risk factors, maternal anemia was common (31.3%). Elderly primi (13.7%), PROM and twin pregnancy in (9.8%) each, bad obstetric history (7.8%). PIH, APH, GDM and oligohydramnios in (3.9%) each. Rh negative pregnancy, grand multipara, teenage pregnancy, ART with hypothyroidism and unbooked pregnancy seen in (1.9%) each. Fetal distress (19.6%). Morbidity was (92.1%). Most common was jaundice (31.9%), sepsis (21.2%). Feeding difficulties (19.1%), TTNB (17%), apnea of prematurity (14.8%). Hypoglycemia and HIE in (12.7%) each. Hypothermia and HMD in (10.6%) each. Seizures in (8.5%) MAS and NEC (4.2%) each, congenital anomalies and hypocalcemia in (2.1%) and mortality in (7.8%). Extreme prematurity, ELBW with sepsis and RDS being common cause of mortality.Conclusions: Iron tablets intake, nutritional care, regular antenatal checkup, spacing pregnancy, avoidance of teenage and elderly pregnancy is important. Improving the infrastructure, manpower in NICU to manage preterm babies, when surfactant and ventilation is given.

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