scholarly journals Hearing impairment among high risk neonates born in a tertiary care hospital in north Kerala: a cross sectional study

2021 ◽  
Vol 7 (3) ◽  
pp. 452
Author(s):  
Ahsanu Zaman Kunnath ◽  
Anwar Sadath Choolakkaparambu Aboobakker ◽  
Bashir Nalakath Kunjimon ◽  
Sandeep Sreedhar
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
High Risk ◽  
Hearing Impairment ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Congenital Hearing Loss ◽  
Cross Sectional ◽  
High Risk Children

<p class="abstract"><strong>Background:</strong> Hearing is necessary for the proper mental and social development of a new-borns child. Delay in diagnosis leads to improper development of social and mental skills. The prevalence of congenital hearing loss is greater than prevalence of screened metabolic syndromes. There are multiple maternal and intrapartum risk factors associated with hearing impairment. Most of the causes are treatable. Objectives was to find out the proportion of hearing impairment in neonates and its risk factors in a tertiary care hospital in north Kerala.</p><p class="abstract"><strong>Methods:</strong> This cross-sectional research was performed in a tertiary care hospital in Northern Kerala between January 2018 and June 2019 after obtaining informed consent and institutional ethical committee clearance among those who fulfilled the inclusion and exclusion criteria. All the high-risk new-borns were subjected to Otoacoustic examination. Those who did not pass the first OAE were subjected to second OAE after one month. Those who did not pass in the examination were subjected to BERA. Those high risk children who did not pass the BERA were considered having hearing impairment and were subjected to further investigation and appropriate management.   </p><p class="abstract"><strong>Results:</strong> The prevalence of hearing impairment was 0.5%. 0.25% were unilateral and 0.25% were bilateral. Pregnancy induced hypertension, premature labour, lower segment Caesarian section, low birth weight, small for gestational age, respiratory distress, hyperbilirubinemia and presence of congenital malformations were significantly associated with hearing impairment.  </p><p class="abstract"><strong>Conclusions:</strong> Since most of the congenital hearing loss among high risk neonates can be treated, a nationwide standardized hearing assessment program is advocated for the early detection of high risk children with hearing loss.</p>

scholarly journals Use of monoclonal antibody therapy for nosocomial SARS-CoV-2 infection in patients at high risk for severe COVID-19: experience from a tertiary-care hospital in Germany

Infection ◽  
2021 ◽  
Author(s):  
Johanna Koehler ◽  
Barbara Ritzer ◽  
Simon Weidlich ◽  
Friedemann Gebhardt ◽  
Chlodwig Kirchhoff ◽  
...  
Keyword(s):  
High Risk ◽  
Tertiary Care Hospital ◽  
Severe Disease ◽  
Treatment Options ◽  
Tertiary Care ◽  
Antibody Therapy ◽  
Additional Treatment ◽  
Care Hospital ◽  
Cross Sectional ◽  
Asymptomatic Patients

AbstractAdditional treatment options for coronavirus disease (COVID-19) are urgently needed, particularly for populations at high risk of severe disease. This cross-sectional, retrospective study characterized the outcomes of 43 patients with nosocomial severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection with and without treatment using monoclonal SARS-CoV-2 spike antibodies (bamlanivimab or casirivimab/imdevimab). Our results indicate that treatment with monoclonal antibodies results in a significant decrease in disease progression and mortality when used for asymptomatic patients with early SARS-CoV-2 infection.

scholarly journals Cross-sectional Study on MyocardialInfarction in Young Adults in an EmergencyDepartment of a Rural Tertiary Care Hospital, Davanagere,Karnataka, India

2021 ◽  
Author(s):  
CH Karthik Reddy ◽  
Mahesh Krishnamurthy ◽  
Ashray Vasanthapuram ◽  
Girish Narayan ◽  
SS Narendra
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Young Adults ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vessel Disease

Introduction: The incidence of Acute Coronary Syndrome (ACS) in the young has been increasing globally. Research in this population has been limited in developed countries or urban areas in developing countries. Identifying the various epidemiologic features in this age group is crucial to understand the disease. Aim: To describe the clinical characteristics of young adults presenting with ACS in a rural tertiary care hospital. Materials and Methods: This cross-sectional study included 50 patients diagnosed with ACS. Data were collected from consecutive patients between the ages of 18 to 45 years diagnosed with ACS between January 2014 to January 2015 in the Emergency Medicine Department of a tertiary care hospital in Davanagere, India. Data were collected on demographic characteristics, risk factors, laboratory tests, and angiographic findings. Range, mean and percentages were calculated for continuous and categorical variables, respectively. A 95% confidence intervals were calculated for all variables. Results: The mean age was 38.1±5.8 years with male preponderance 46 (92%). Risk factors were smoking 36 (72%), diabetes 17 (34%), hypertension 6 (12%) and Body Mass Index (BMI) >23 kg/m2, 36 (72%). Anterior Wall Myocardial Infarction (AWMI) was observed in 35 (70%) of subjects with angiography revealing Single Vessel Disease (SVD) 28 (56%), Double Vessel Disease (DVD) 5 (10%), Triple Vessel Disease (TVD) 3 (6%) and Myocardial Infarction with Non-Obstructive Coronary Artery Disease (MINOCA) 11 (22%). Three patients died during their course of treatment before initiating an interventional procedure. Conclusion: Smoking, diabetes mellitus and elevated BMI are associated with ACS among young patients. Interventions targeting these risk factors among younger individuals should be developed.

scholarly journals A Clinical Study of Secondary Glaucoma with Special Reference to Its Proportion, Causes and Its Risk Factors in a Tertiary Care Hospital - A Cross Sectional Study

2021 ◽  
Vol 8 (01) ◽  
pp. 23-27
Author(s):  
Partha Chakma ◽  
Debal Kisor Pal ◽  
Amar Kanti Chakma
Keyword(s):  
Risk Factors ◽  
Special Reference ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Secondary Glaucoma ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Common Cause

BACKGROUND Secondary glaucoma is an anatomically identifiable abnormality which in turn is an underlying cause of the events that lead to aqueous outflow obstruction and rise in the intraocular pressure. This prospective study mainly highlights the secondary glaucoma with special reference to its proportion, causes and its risk factors in a tertiary care hospital. METHODS This study was a cross sectional study. Patients, who attended the Department of Ophthalmology after fulfilling the inclusion and exclusion criteria diagnosed with secondary glaucoma, were included in the study. The study period was from February 2018 to June 2020. A standard form was filled up for each patient documenting parameters and findings of various examinations and was evaluated as per protocol. RESULTS Secondary glaucoma was seen in 0.2 % patients who visited during the study period. Out of 106 patients, males were 50, females were 56, with a male: female ratio of 1:1.1. The most common cause of secondary glaucoma was lens induced glaucoma seen in 44.34 % followed by uveitic glaucoma in 20.8 % cases, traumatic 17.9 %, neovascular 10.4 %, pseudoexfoliation glaucoma 2.8 %, pigmentary glaucoma 1.9 %, silicon oil induced 0.9 %, and uveitis-glaucomahyphema syndrome in 0.9 % cases. Around thirty five percent (34.9 %) cases presented with sudden onset of painful diminution of vision with nausea and vomiting. CONCLUSIONS Secondary glaucoma is still one of the prevalent diseases in this part of country. Lens induced glaucoma is still the most common cause of secondary glaucoma. Hypermature cataract, uveitis, trauma and neovascularisation are the different risk factors. KEYWORDS Secondary Glaucoma, Lens Induced Glaucoma, Phacomorphic Glaucoma, Uveitic Glaucoma

scholarly journals ASSESSMENT OF AWARNESS, KNOWLEDGE AND RISK FACTORS OF CHRONIC KIDNEY DISEASE AMONG DIABETES MELLITUS AND HYPERTENSIVE PATIENTS AT A TERTIARY CARE HOSPITAL

2020 ◽  
pp. 1-3
Author(s):  
K. Jesindha Beyatricks ◽  
Deepa shruthi G ◽  
Fizia Mohammadi ◽  
Feba Thomas ◽  
Omid Reza
Keyword(s):  
Risk Factors ◽  
Positive Attitude ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Negative Attitude ◽  
Good Knowledge ◽  
Care Hospital ◽  
Cross Sectional ◽  
Poor Knowledge ◽  
Hypertensive Patients

A prospective cross sectional study on the awareness, knowledge and risk factors of CKD among Diabetic and Hypertensive patients was conducted in the outpatient and inpatient wards of a tertiary care hospital in Bengaluru. A total number of 100 patients were included in the study. The results indicated that, out of 100 patients, 38% was having knowledge and 62% were without knowledge. 43% were having positive attitude and 57% with a negative attitude. It was found that majority of the people were without knowledge, that is 62% and negative attitude 57%. The study revealed that among educated people, 55.55% was having poor knowledge and 44.44% was having good knowledge. Among uneducated people, 64.86 % was having poor knowledge and 35.13 % was having good knowledge. Among 100 participants, 43% has positive attitude and 57% has negative attitude.

scholarly journals Postpartum Hemorrhage in Pregnancy beyond 40 Weeks of Gestation in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (237) ◽  
Author(s):  
Rashmi Bastakoti Gaire ◽  
Suman Raj Tamrakar ◽  
Anjana Singh Dongol
Keyword(s):  
High Risk ◽  
Confidence Interval ◽  
Postpartum Hemorrhage ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
In Pregnancy

Introduction: Postpartum hemorrhage is defined as a blood loss of 500ml or more within 24 hours after birth. It is the leading cause of maternal mortality in low-income countries and the primary cause of nearly one-quarter of all maternal deaths globally. It occurs in up to 18% of total births. Post-dated pregnancy is a high-risk pregnancy with increased maternal morbidity. This study aims to determine the prevalence of postpartum hemorrhage in pregnancy beyond 40 weeks of gestation in a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted among pregnant women beyond 40 weeks in Dhulikhel hospital from October 2016 to March 2017. The study was conducted after ethical clearance from the hospital research committee (reference number#128/16). The sample size was calculated and convenient sampling was done. Statistical Package for the Social Sciences is used for analysis. Point estimate at 95% confidence interval was calculated along with frequency and percentage for binary data. Results: Out of 465 ladies enrolled in this study postpartum hemorrhage was seen in 6 (1.29%) (95% Confidence Interval = 0.267-2.31), and the mean age was 24.25+4.8. About 346 (74.4%) had a normal delivery, 104 (22.36%) had cesarean section and 15 (3.22%) had instrumental delivery. Conclusions: Postpartum haemorrhage prevalence is low among the pregnant women beyond 40 weeks compared to the standard study. Postpartum hemorrhage is the common leading cause of maternal mortality. So high-risk cases should be identified and active management should be done to reduce morbidity and mortality.

scholarly journals Prevalence of high risk obstructive sleep apnoea by Berlin questionnaire in patients with hypertension: study from a tertiary care hospital

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Ozaifa Kareem ◽  
Masood Tanvir ◽  
G. N. Bader
Keyword(s):  
High Risk ◽  
Obstructive Sleep Apnoea ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sleep Apnoea ◽  
Berlin Questionnaire ◽  
Care Hospital ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Mean

Abstract Background Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of 6 months. OSA was evaluated using the Berlin questionnaire while the daytime sleepiness was determined using Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score >16) was found to be 32.5% (95% CI, p < 0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 37.41 ± 3.396 cm, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 35.45 ± 2.652 cm, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p<0.001). The mean blood pressure (BP) ≥133.52/84.37 mmHg was recorded in patients with a high risk of OSA (95% CI, P < 0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P < 0.05). Conclusion In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

scholarly journals Frequency of anemia and causative risk factors in patients presenting to tertiary care hospital: A cross sectional study.

2020 ◽  
Vol 27 (09) ◽  
pp. 1966-1970
Author(s):  
Saima Yasmin Qadir ◽  
Hajira Sultana ◽  
Saima Ashraf ◽  
Shazia Siddiq ◽  
Asia Fayyaz
Keyword(s):  
Risk Factors ◽  
Socioeconomic Status ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Outpatient Department ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical University

Objective: To determine the frequency of anemia and its causative risk factors in patients attending the gynecology outpatient department of Nishtar Medical University and Hospital. Study Design: Cross sectional study. Setting: Gynecology Outpatient Department attendees of Nishtar Medical University and Hospital. Period: 1st September to 31st December 2019. Material & Methods: Total 361 females between 19-49 years of age were enrolled and included those patients who consented to be tested for blood hemoglobin estimation. Their brief history was taken after proper consent according to predesigned proforma to rule out the risk factors. Patients with chronic kidney disease, chronic lung diseases and liver diseases were excluded. Blood test was done by obtaining the blood sample by finger prick method. Hemoglobin analysis was performed by portable Hemocueanalyser. Frequency of anemia, severity of anemia and their stratification was performed against the risk factors like age, educational status, socioeconomic status, status of pregnancy, parity and contraception were obtained to rule the causative factors. Anemia was defined per standard criteria as hemoglobin less than 11gm/dl. Results:  Majority of patients 65% were between 19-35 years of age and 34% were 36-49years of age. Frequency of pregnant patients and non-pregnant patients was 63.4% and 36.6%.  Frequency of anemia was 56.8%, mean hemoglobin 10.48±1.18 with mild, moderate and severe anemia were 36.8%, 17.2% and 2.8%. Majority of females 82.9%, never went to school and had primary education, 71.70% belong to very poor and poor socioeconomic status, 79.02% were multipara and 81.95% never and infrequently practiced the contraceptive methods. Conclusion:  Frequency of anemia is very high in females presenting to tertiary care hospital being more common in younger age group. Frequent pregnancies, poor socioeconomic status and low level of educational attainment were the major determinants of anemia in females.

scholarly journals The Baseline Characteristics of Patients with COVID-19 and Impact of Various Risk Factors on the Outcome of Patients Admitted in Tertiary Care Hospital.

2021 ◽  
Author(s):  
Samiullah Shaikh ◽  
Faiza Deedar ◽  
Tara Chand Devrajani
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Tertiary Care Hospital ◽  
Risk Group ◽  
Tertiary Care ◽  
Ventilatory Support ◽  
Severity Of Illness ◽  
University Hospital ◽  
Categorical Variables ◽  
Care Hospital

Abstract Background: The outbreak caused by novel coronavirus was first reported in Wuhan, China in December 2019 when a new pathogen was discovered from the bronchoalveolar lavage fluid of the patient suffering from pneumonia. Globally over 81.47 million confirmed cases and 1.79 million deaths has been reported. The clinical spectrum ranges from mild influenza-like illness to severe life threatening respiratory disease requiring ventilatory support to death. The purpose of this study was to evaluate the baseline carecteristic of the patients and impact of various risk factors on the outcome of patients admitted in tertiary care hospital. MATERIALS AND METHODSStudy Area and Period: This study was conducted at Liaquat University Hospital from April 2020 to September 2020. Study Design: Cross-Sectional Descriptive.Inclusion Criteria: The patients were included on the basis of diagnosis of COVID-19 confirmed on reverse transcription Polymerase Chain reaction (RT-PCR) test. Categorical variables such as age, sex, Gram-Covid risk category ,diabetes mellitus, hypertension, renal, pulmonary disease, obesity, outcome of patient were presented as frequency and percentage RESULTS: This study included 235 consecutive patients admitted at Liaquat University Hospital from April 2020 to September 2020. There were 187(79.6%) male and 48(20.4 %) female. The age < 65 years were present in 80 ( 34%) and ≥ 65 155(66%) patients. The most prevalent symptoms were fever ,breathlessness, cough, anorexia, fatigue in all 235(100% ) patients. Severity of illness according to Gram-Covid Score 18 (7.7%) patients were in low-risk group, 93(39.6%) in moderate risk group and 124 (52.8%) in High risk group.There were no risk factors in 121(51.5%) , one risk factor in 49(20.9%), two risk factors in32(13.6%) , three risk factors in 18( 7.7%) and four risk factors in 15(6.4%) patients.The outcome of patients showed 57(24.3%) deaths, 107 (45.5%) patients had prolong stay and 71(30.2%) patients recovered. A strong relationship was observed between the outcome of patient with age, number of risk factors, severity of illness according to gram - Covid score whereas insignificant relationship with the sex of patients.Conclusion: COVID-19 patients clinically present with fever, cough and breathlessness. Majority of patients present with moderate to high severity. Patient with advanced age, high risk on gram-Covid score with multiple comorbidities are particularly susceptible to adverse outcome.

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