scholarly journals A prospective study of the bacteriological profile and risk factors of infection after internal fixation of close fractures of long bones

2020 ◽  
Vol 6 (2) ◽  
pp. 345
Author(s):  
Munin Borgohain ◽  
Debasish Bora ◽  
Aswin Deepak Rajan
Keyword(s):  
Risk Factors ◽  
Infection Rate ◽  
Plate Fixation ◽  
Antibiotic Sensitivity ◽  
Immunosuppressive Drugs ◽  
Long Bone ◽  
X Rays ◽  
North East India ◽  
North East ◽  
Bacteriological Profile

<p class="abstract"><strong>Background:</strong> Infection in implant related procedures is dreaded due to difficulty in getting rid of it. Disappointment to patients and surgeons, drainage of health care and patients’ resources is significant. Causes and risk factors are many related to host, environment and procedure. The bacteriological profile and antibiotic sensitivity have been changing trend with emerging resistance to many drugs.</p><p class="abstract"><strong>Methods:</strong> A prospective observational study of 941 patients with operative fixation of long bone closed fractures. The details of the procedure, host characteristics were noted. Followed up in ward post operatively and after discharge to identify the cases of surgical site infection. Once identified they were evaluated with X-rays and lab parameters. Wound swabs or pus samples taken to find out the organisms and cultured to find the sensitivity.<strong></strong></p><p class="abstract"><strong>Results:</strong> 116 patients (86 males and 30 females) developed SSI (incidence 12.42%). Plate fixation (18.20% infection rate), operative time &gt;1 and half hours (15.73% rate), fracture femur (16.66% rate), ORIF (14.38% rate), age &gt;60 yrs were some of the risk factors. Co-morbidities like anaemia, diabetes, liver disease, lung disease, immunosuppressive drugs, hypertension, smoking, alcoholics had significant association with SSI. <em>Staphylococcus aureus</em> was the most common organism. Gram positive showed highest sensitivity to linezolid, vancomycin and tetracycline. Gram negative showed highest sensitivity to colistin and tigecycline.</p><p class="abstract"><strong>Conclusions:</strong> Infection rate should be less than 1% and hence risk factors encompassing preoperative, intraoperative and postoperative period are to be controlled. Probably the first study from north east india showing the burden of orthopaedic SSI.</p>

scholarly journals Etiological profile of pyodermas in a tertiary care hospital in North-East India and their antibiotic sensitivity pattern

2019 ◽  
Vol 6 (1) ◽  
pp. 20
Author(s):  
Bijayanti Devi ◽  
Kamal Das ◽  
Suman Gupta
Keyword(s):  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Care Hospital ◽  
Age Group ◽  
Total Study Population ◽  
North East India ◽  
North East ◽  
Pigmentary Disorders ◽  
Sensitivity Pattern ◽  
Study Population

<p class="abstract"><strong>Background:</strong> Hypermelanoses involving predominantly the face and the neck is relatively common and often presents a complex diagnostic problem. The present study was done in the study population of 500 patients of facial pigmentation, attending the skin outpatient department in AarupadaiVeedu Medical College and Hospital from October 2015 to September 2017. Aim and objective of the study was to study various clinical patterns of facial pigmentation, their clinical characteristics, their association with other pigmentary disorders and to evaluate the different etiotogical and precipitating factors.</p><p class="abstract"><strong>Methods:</strong> In this study, a special proforma was prepared. Patients were thoroughly interviewed and examined to find out dermatological and systemic diseases and they were subjected to investigations to evaluate different etiological factors and diagnose the clinical type of facial pigmentation.<strong></strong></p><p class="abstract"><strong>Results:</strong> The present study showed a strong female preponderance. Among the total study population there were 55% cases of melasma, 20% cases of Riehls melanosis, 10% cases of periorbital pigmentation and 5% of miscellaneous causes.</p><p class="abstract"><strong>Conclusions:</strong> Facial pigmentation was commonly seen in the females. 21-30 years age group was the most commonly affected age group in all types of facial pigmentation. Melasma, Riehls melanosis and periorbital pigmentation were the most common clinical types of facial pigmentation observed.</p>

Prevalence and Risk Factors of Hypertension among Mizo Population:A Population-Based Epidemiological Study from North East India

2018 ◽  
Vol 115 (10) ◽  
pp. 1947 ◽  
Author(s):  
Prasanta K. Borah ◽  
Suman K. Paine ◽  
Hem Ch Kalita ◽  
Dipankar Biswas ◽  
Dilip Hazarika ◽  
...  
Keyword(s):  
Risk Factors ◽  
Epidemiological Study ◽  
Population Based ◽  
North East India ◽  
North East

Prevalence of cardiovascular risk factors among tribal and non‐tribal populations with East Asian Ancestry from North East India

2019 ◽  
Vol 31 (5) ◽  
Author(s):  
Varhlun Chhungi ◽  
Somorjit Singh Ningombam ◽  
Suniti Yadav ◽  
Huidrom Suraj Singh ◽  
Naorem Kiranmala Devi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
East Asian ◽  
North East India ◽  
North East ◽  
Asian Ancestry ◽  
Tribal Populations ◽  
East Asian Ancestry

scholarly journals Association of ACE I/D Gene Polymorphism and Related Risk Factors in Impaired Fasting Glucose and Type 2 Diabetes: A Study Among Two Tribal Populations of North-East India.

2021 ◽  
Author(s):  
SUNANDA RAJKUMARI ◽  
SOMORJIT SINGH NINGOMBAM ◽  
VARHLUN CHHUNGI ◽  
MASAN KAMBO NEWMEI ◽  
NAOREM KIRANMALA DEVI ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Health Concern ◽  
Environment Interaction ◽  
Hilly Terrain ◽  
North East India ◽  
Physiological Variables ◽  
North East ◽  
Tribal Populations

Abstract AIMType 2 diabetes is a serious public health concern in India, even the indigenous tribal populations are not felt unaffected. The present study aims to understand the association of major risk factors i.e obesity, hypertension, dyslipidemia, ACE I/D polymorphism with impaired (IFG) and type 2 diabetes (T2D) among two different Mendelian populations of North East India. METHODDemographic, somatometric and physiological variables along with fasting blood samples were collected from 609 individuals. ACE I/D polymorphism was screened. RESULTACE I/D polymorphism was found to follow HWE among Liangmai tribe but not among Mizo tribe. Distribution of DD genotype/D allele was found to be significantly higher for T2D among Mizo (OR 2.10; 95% CI 1.10-4.39, OR 2.10;1.16-4.09 respectively ).Significant association between DD genotype/D allele of ACE I/D polymorphism and TC in both IFG (OR 2.22; 95% CI 1.14-4.32) and T2D (OR 2.53;95%CI 1.51-4.23) were observed . LDL was also found to posed significant risk for IFG (OR 2.10;95% CI 1.10-3.91) and T2D (OR 1.04; 95%CI 1.02-1.06). CONCLUSIONThe present study is an example of gene-environment interaction where DD genotype or D allele and dyslipidemia (high TC and high LDL) are posing risk for IFG and T2D both independently and in combination only among Mizo tribe with relatively less physical activity attributed to their residence in less hilly terrain, but Liangmai tribe which resides in high hilly terrain shows no such association.

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