scholarly journals Different patterns of cutaneous manifestation of diabetes mellitus type-2 observed in tertiary care centre of South West Rajasthan

2021 ◽  
Vol 7 (4) ◽  
pp. 341-346
Author(s):  
Kalpana Gupta ◽  
Anurag Bareth ◽  
Charul Agrawal
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Bacterial Infections ◽  
Acanthosis Nigricans ◽  
Statistical Tests ◽  
Tertiary Care ◽  
Diabetes Mellitus Type ◽  
P Value ◽  
Cutaneous Manifestations

Diabetes mellitus (DM) is a common endocrinal disorder caused by complex interaction of genetics and environmental factors. Various dermatological features are known to be cutaneous markers of diabetes mellitus like diabetic dermatopathy, acrochordons, acanthosis nigricans and bullous diabeticorum, etc. An observational cross-sectional study on a total of 400 patients of Diabetes Mellitus Type-2. A complete cutaneous examination was done in all cases to observe for the presence of any specific or nonspecific dermatosis. All the statistical tests were two sided and P-value <0.05 was considered as significant level. This study showed that in specific cutaneous disorders, Acrochordon 138(34.5%) was the most common manifestation which was followed by, Bacterial Infections 93(23.5%), Dermatophytosis 77(19.2%), Candidiasis 76(19%), Acanthosis nigricans 50(12.5%) and Onychomycosis 33(8.25%) in decreasing order. Xerosis 259(64.7%) was the commonest manifestation in non-specific cutaneous disorders followed by, Generalized pruritus 200(50%), Seborrheic keratosis 35(8.75%) in decreasing order. Cutaneous manifestations are quite common in uncontrolled (HbA1c>7gm) type 2 diabetes mellitus as compare to controlled group. Uncontrolled group is more prone to develop diabetic complication like hypertension, diabetic retinopathy and peripheral neuropathy etc. It is concluded that, Diabetes mellitus Type-2 involves the skin quite often and whenever patients present with multiple skin manifestation and then diabetic statusshould be checked and controlled.

scholarly journals Dysmetabolic Syndrome in a Man with a Novel Mutation of the Aromatase Gene: Effects of Testosterone, Alendronate, and Estradiol Treatment

2004 ◽  
Vol 89 (1) ◽  
pp. 61-70 ◽  
Author(s):  
Laura Maffei ◽  
Yoko Murata ◽  
Vincenzo Rochira ◽  
Gloria Tubert ◽  
Claudio Aranda ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Diabetes Mellitus Type 2 ◽  
Acanthosis Nigricans ◽  
Diabetes Mellitus Type ◽  
Bone Maturation ◽  
Bilateral Cryptorchidism ◽  
High Doses

We present the fourth case of an adult man (29 yr old) affected by aromatase deficiency resulting from a novel homozygous inactivating mutation of the CYP19 (P450arom) gene. At first observation, continuing linear growth, eunuchoid body proportions, diffuse bone pain, and bilateral cryptorchidism were observed. The patient presented also a complex dysmetabolic syndrome characterized by insulin resistance, diabetes mellitus type 2, acanthosis nigricans, liver steatohepatitis, and signs of precocious atherogenesis. The analysis of the effects induced by the successive treatment with high doses of testosterone, alendronate, and estradiol allows further insight into the roles of androgens and estrogens on several metabolic functions. High doses of testosterone treatment resulted in a severe imbalance in the estradiol to testosterone ratio together with the occurrence of insulin resistance and diabetes mellitus type 2. Estrogen treatment resulted in an improvement of acanthosis nigricans, insulin resistance, and liver steatohepatitis, coupled with a better glycemic control and the disappearance of two carotid plaques. Furthermore, the study confirms previous data concerning the key role of estrogens on male bone maturation, at least in part, and regulation of gonadotropin secretion. The biopsy of the testis showed a pattern of total germ cell depletion that might be due to the concomitant presence of bilateral cryptorchidism. Thus, a possible role of estrogen in male reproductive function is suggested but without revealing a direct cause-effect relationship. Data from this case provide new insights into the role of estrogens in glucose, lipid, and liver metabolism in men. This new case of aromatase deficiency confirms previous data on bone maturation and mineralization, and it reveals a high risk for the precocious development of cardiovascular disease in young aromatase-deficient men.

scholarly journals Faktor-Faktor yang Mempengaruhi Kepatuhan Pengobatan pada Pasien Diabetes Mellitus Rawat Jalan di RSUD Sukoharjo

2020 ◽  
Vol 17 (2) ◽  
pp. 110-120
Author(s):  
Tri Yulianti ◽  
Lusi Anggraini
Keyword(s):  
Diabetes Mellitus ◽  
Medication Adherence ◽  
Diabetes Mellitus Type 2 ◽  
Sampling Technique ◽  
Diabetes Mellitus Type ◽  
P Value ◽  
Affecting Factors ◽  
Chi Square ◽  
Cross Sectional

Diabetes mellitus is a chronic metabolic with high prevalence and it can increase the risk of the complications, if it not handled properly. Medication adherence is one of the determining factor to achive therapeutic outcome. This research aims to determine the affecting factors of adherence in  diabetes mellitus type 2 outpatient at RSUD Sukoharjo in 2020. This research type is  cross sectional with a purposive sampling technique. A total of 85 patients diabetes mellitus type 2 outpatient at RSUD Sukoharjo with inclusion criteria received OAD therapy (Oral Antidiabetic Drugs) or a combination of OAD with insulin for at least 1 month, recruited in this study. The data was collected from medical records and questionnaires. Adherence was measured by using the MARS 5 questionnaire (Medication Adherence Report Scale 5). Factors contributing to medication adherence was analyzed by using chi-square test. The results showed that 37 respondents (43.5%) were obedient. The significant factors of medication adherence are monthly income (p-value = 0.018 and OR = 2.887), Medication (p - value = 0.007 and OR = 3,551), the frequency of treatment (p-value = 0.006 and OR = 3,529) and blood glucose level (p-value = 0.006 and OR = 3,529).

scholarly journals The Effect Of Diabetic Foot Spa On Ankle Brachial Index And Foot Sensitivity Of Diabetes Mellitus Type 2

2019 ◽  
Vol 6 (3) ◽  
pp. 672
Author(s):  
Erika Martining Wardani ◽  
Lono Wijayanti ◽  
Nur Ainiyah
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Diabetes Mellitus Type 2 ◽  
Ankle Brachial Index ◽  
Sampling Technique ◽  
Diabetes Mellitus Type ◽  
Control Group ◽  
P Value ◽  
Control Group Design

Diabetes Mellitus (DM) is a metabolic disorder which marked by the hyperglycemia that appeared because of insulin secretion disorder and/or the increase of cellular insulin resistance. DM patients have a higher risk to experience foot problems due to blood vessels disorders causing the circulation of blood from legs is decreased. Purposed this research is diabetes could be prevented by doing a foot spa diabetic which the activities include foot exercises, warm water cleansing and massage. The method used in this study is Quays Experiment pre-post control group design. The population on this study was patients with Diabetes Mellitus Type 2 in Waru health center. The sample used was 60 people, divided into 2 groups; intervention and control group, with sampling technique of simple random sampling. The data collection was using observation sheets of diabetic foot SPA; the tool used to assess blood glucose levels was glucometer, whereas cotton, brush and needle were used to assess the foot sensitivity. The data was then analyzed with t-test. The result of the study showed that there were effecton the foot sensitivity (t=10,73, p value =0, 000) and there were effectdecrese on ankle brachial index(t=12,34, p value =0, 000). It is important for families and communities to give motivation to the diabetes mellitus patients to do diabetic foot SPA as one of alternative therapies to prevent foot complications such as foot ulcers and even amputation

scholarly journals HUBUNGAN ANTARA SELF EFFICACY DENGAN QUALITY OF LIFE PADA PASIEN DIABETES MELLITUS TIPE 2 DI WILAYAH KERJA PUSKESMAS KEBONSARI SURABAYA

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Nety Mawarda Hatmanti
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Self Efficacy ◽  
Diabetes Mellitus Type 2 ◽  
Metabolic Diseases ◽  
Diabetes Mellitus Type ◽  
P Value ◽  
Cross Sectional

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetes Mellitus type 2 is a significant problem in the global health. This research was purposed to find out the correlation between self-efficacy and quality of life of the patients with Diabetes Mellitus type 2. The design of this research was cross sectional, in which 16 patients visiting the polyclinic of Puskesmas Gayungan Surabaya were chosen as the samples. The result of research using Spearman rho test showed that there was a significant correlation between self-efficacy and quality of life proved by the p value = 0.016 < 0.05. The conclusion of this research found a positive intermediate correlation between selfefficacy and quality of life so that nurses are required to ask the family to increase the patients’ self-efficacy. 

scholarly journals ANTI-HYPERGLYCEMIC EFFECT OF KUNDRU (COCCINIA INDICA) ON PATIENTS OF DIABETES MELLITUS TYPE-2

2020 ◽  
pp. 29-35
Author(s):  
Mohd Junaid ◽  
Bhavna Singh ◽  
Sahana vats ◽  
Sanandan Thapliyal ◽  
Shalini Thapliyal
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetes Mellitus Type 2 ◽  
Blood Sugar Level ◽  
Treated Group ◽  
Diabetes Mellitus Type ◽  
P Value ◽  
Coccinia Indica ◽  
Trial Drug

The disease Diabetes or Madhumeha is well documented in all perennial sources of Ayurvedic wisdom. The present study was done to evaluate the efficacy of Bimbi (Coccinia indica) in the patients of Diabetes mellitus type-2 through single blind study. Total 30 patients were selected and divided into two groups, 15 patients in each group i.e., A (Bimbi) & B (Barley). In this study it has been found that Madhumeha affects not only in elderly people but in adults too with slight female preponderance. The present study confirmed that after the treatment of 60 days, Bimbi (Coccinia indica) was found effective in treatment of Madhumeha and reduced majority of the symptoms of illness that including Prabootha mootrata (Excessive urination), Atitrushna (Excessive thirst), Avila mootrata (Turbid urine) and Dourbalya (Weakness). There was significant improvement in all the laboratory parameters in patients of Bimbi (Coccinia indica) treated group. The outcome showed that mean reduction in fasting blood sugar level was 19.86%, in PP blood sugar level was 24.52% and in HbA1c level was 8.4%.These outcomes suggest that the results of trial drug i.e., Coccinia indica (Bimbi) powder was highly significant at p-value <0.001. The drug Bimbi showed effectiveness in reducing FBS, PPBS and HbA1c, as results were highly significant. Barley powder used as placebo didn't showed reduction in FBS, PPBS and HbA1c.

scholarly journals The Effect of Hypnotherapy on the Reduction of Blood Glucose Levels in Diabetes Mellitus Type-2

2021 ◽  
pp. 83-92
Author(s):  
Yusran Hasymi ◽  
. Suwanto
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Control Group ◽  
P Value ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Energy Therapy

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, which occurs due to abnormalities in insulin secretion, insulin action, or both. Most cases of diabetes mellitus are diabetes mellitus type-2. The purpose of this study was to determine the effect of hypnotherapy on reducing blood glucose levels in patients with diabetes mellitus type-2. The research used a quasi-experimental design with a non-equivalent control group design. Purposive sampling was used, and 30 respondents selected. The instrument in this study was a single stick tool. The intervention group was given standard therapy treatment in the form of bio-energy therapy and hypnotherapy, while the control group was only given standard therapy treatment in the form of bio-energy therapy. Univariate analysis of the results indicates that the average blood glucose level before treatment was 234.67 mg/dl and after treatment was 194.67 mg / dl. Bivariate analysis based on the results of the Wilcoxon Signed Ranks Test obtained a p-value of 0.002 (p-value <0.05). This means that hypnotherapy reduced blood glucose levels in diabetes mellitus type-2 sufferers. This study recommends the nursing profession apply hypnotherapy as an alternative or non-pharmacological complementary therapy that can be used to reduce blood glucose levels in people with diabetes mellitus type 2.   Keywords: Hypnotherapy, diabetes mellitus type 2, blood glucose levels

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