scholarly journals Predictors of Nicotine Dependence among Adult Male Midwakh and Cigarette Smokers

Author(s):  
Shatah Al Sharbatti ◽  
Rizwana B. Shaikh ◽  
Jayadevan Sreedharan ◽  
Jayakumary Muttappallymyalil ◽  
Michael Weizman

Objectives: Midwakh is a popular form of smoking in the Middle East. This study aimed to assess predictors of nicotine dependence among exclusive cigarette and midwakh smokers in the United Arab Emirates (UAE). Methods: This cross-sectional study was conducted from September to December 2015 in Ajman, UAE. A convenience sampling strategy was used to recruit adult male smokers aged ≥18 years who exclusively smoked either cigarettes or midwakh. A validated self-administered questionnaire was used to collect data from the participants, with nicotine dependence assessed using the Modified Fagerström Test for Nicotine Dependence. In addition, testing was performed to determine levels of salivary cotinine and exhaled breath carbon monoxide (CO). Results: A total of 88 adult male smokers were included in the study, of which 40 (45.5%) were cigarette smokers and 48 (54.5%) smoked midwakh. Most participants were 26–35 years of age (48.9%), followed by 18–25 years (30.7%) and ≥35 years (20.5%). Use of midwakh was associated with a more than three-fold increase in the risk of moderate to high nicotine dependence in comparison with cigarette smoking. Moreover, for each unit increase in CO level, there was a 10% increase in the risk of nicotine dependency. There was also a significant association between nicotine dependence level and depth of inhalation (P = 0.023).  Conclusion: Type of smoking and CO levels were found to be significant predictors of nicotine dependence among adult male smokers. In particular, greater dependency was observed among midwakh smokers compared to those who smoked cigarettes. Keywords: Tobacco Use; Cigarette Smoking; Addictive Behaviors; Nicotine; Risk Assessment; Carbon Monoxide; Cotinine; United Arab Emirates.

2019 ◽  
Vol 22 (7) ◽  
pp. 1114-1122 ◽  
Author(s):  
Douglas Oliveri ◽  
Qiwei Liang ◽  
Mohamadi Sarkar

Abstract Introduction Real-world evidence regarding likely long-term health effects of e-vapor products (EVP) under actual use conditions relative to cigarette smoking is not well studied. Methods In this cross-sectional, observational study, biomarkers of exposure (BOE) to select harmful and potentially harmful constituents and biomarkers of potential harm (BOPH) relevant to smoking-related diseases were measured in exclusive adult EVP users (AEVP, n = 144) and exclusive adult cigarette smokers (AS, n = 73). AEVP used their own brand of EVP for 6+ months following 10+ years of cigarette smoking and AS smoked own brand of cigarettes for 10+ years. Subject recruitment and informed consent were obtained online and urine/blood samples were collected at local clinical laboratories, representing a new paradigm for collecting real-world evidence. Results The levels of total NNAL (NNK metabolite), 3-hydroxypropyl mercapturic acid (acrolein metabolite), and carboxyhemoglobin (carbon monoxide measure) were 46% to 86% lower in AEVP compared with AS (p ≤ .0001) as was nicotine equivalents (nicotine and its five metabolites; 36%, p < .01). The levels of some BOPH were significantly lower in AEVP compared with AS for 11-dehydrothromboxane-B2 (29%, p = .04; platelet activation), 8-epi-prostaglandin F2α (23%, p = .02; oxidative stress) and soluble intercellular adhesion molecule-1 (16%, p = .02; endothelial function). Conclusions This study demonstrates the feasibility of a new approach for collecting real-world evidence. Substantially lower levels of BOEs (NNK, nicotine, acrolein, carbon monoxide) and favorable differences in BOPHs (platelet activation, oxidative stress, endothelial function) suggest EVP users may have lower health risks than cigarette smokers. Implications Cigarette smoking causes serious diseases. Switching from a combustible tobacco product to a noncombustible product is a potential harm reduction pathway for adult smokers unable or unwilling to quit. Real-world evidence regarding the relative risk of EVP use compared with cigarettes is not well established. This study provides data specific to BOE to tobacco smoke constituents and biomarkers of potential harm collected under actual use conditions in a real-world setting. The totality of evidence suggests that exclusive EVP use may present lower health risk compared with smoking cigarettes.


1970 ◽  
Vol 2 ◽  
pp. 49-53 ◽  
Author(s):  
Mohammed Montasir Islam ◽  
Md Ruhul Amin ◽  
Shameema Begum ◽  
Dilruba Akther ◽  
Abedur Rahman

The present study was carried out to observe the changes in total count in WBC in cigarette smokers. The study population consisted of 105 adult male smokers and non-smokers, aged 20~40 years, from different socio-economic classes. Among them, 30 apparently healthy non-smokers were taken as control. 75 apparently healthy smokers, who had the history of smoking of one or more cigarette per day, regularly for at least last one year, were taken as the study group. Smokers were again subdivided into three categories according to the number of cigarettes they consumed per day. For statistical analysis unpaired ‘t' test was used for comparison. Mean ± SD of Total count of WBC in non smokers and smokers were 7501.66 ± 929.4 /mm3 and 9171.3 ± 1037.7/mm3 respectively. Smokers had significantly (P<0.001) higher WBC counts than non-smokers. In addition, WBC count was found increased with intensity of smoking. The smokers who were smoking e 20 cigarettes per day had the higher total WBC count than those who were smoking lesser. The findings of the present study suggest that cigarette smoking may cause increased the total count of WBC, which may predict high risk for some fatal diseases. Key words: Cigarette Smoking; White Blood Cell; Adult Male DOI:10.3329/jbsp.v2i0.985 J Bangladesh Soc Physiol. 2007 Dec;(2): 49-53


2015 ◽  
Vol 4 (2) ◽  
pp. 38-44
Author(s):  
Muhammad Usman Khan ◽  
Alisha Noreen ◽  
Ramsha Kafeel ◽  
Yusra Sabahat

BACKGROUND Shisha and cigarette are the two most common type of tobacco smoking. Cigarette and shisha smoking have grown fast in different ages globally. Shisha and cigarette both contain chemicals that affect health badly and can cause common diseases such as cough and some life threatening diseases like cancer, emphysema and bronchitis also affect bones causing osteoporosis and decrease functional capacities of lung. There are no proper guidelines for the awareness of the public about the hazards of shisha smoking as they are present for cigarette smoking but it’s a fact that shisha smoking is as harmful as cigarette smoking. OBJECTIVES To compare the effect of Inspiratory Reserve Volume (IRV) on shisha and cigarette smokers by using spirometer. STUDY DESIGN AND SAMPLING TECHNIQUE Cross-sectional survey was steered, convenient sampling was used. STUDY SETTINGS & PARTICIPANTS The study was conducted on 50 participants of Ziauddin College of Nursing and Ziauddin College of Physical Therapy RESULTS IRV is more compromised in shisha smokers than in cigarette smokers. As far as deciding between health concerning effects of shisha and cigarette smokers, the shisha smoking effects are same as cigarette smoking. CONCLUSION Shisha smokers have more exposure to tobacco than cigarette smokers. IRV is disturbed by both means of smoking but shisha smoking has more potential risks. Keywords Inspiratory Reserve Volume, Spirometer, Cigarette, Smokers, Shisha, Emphysema, Bronchitis


BMJ Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. E024497 ◽  
Author(s):  
Brian Vincent Fix ◽  
Danielle Smith ◽  
Richard O’Connor ◽  
Bryan W Heckman ◽  
Marc C Willemsen ◽  
...  

ObjectivesExisting evidence shows that co-occurring use of tobacco and cannabis is widespread. Patterns of co-use of tobacco and cannabis may change as more jurisdictions legalise medicinal and/or recreational cannabis sales. This analysis examined predictors of current cannabis use and characterised methods of consumption among smokers and non-smokers in a context where cannabis use is legal.SettingThe 2015 International Tobacco Control Netherlands—Gold Magic Survey conducted between July and August 2015.ParticipantsParticipants (n=1599; 1003 current smokers, 283 former smokers and 390 non-smokers) were asked to report their current (past 30-day) use of cigarettes and cannabis. Cigarette smokers reported whether they primarily used factory made of roll-your-own cigarettes. Those who reported any cannabis use in the last 30 days were asked about forms of cannabis used. X2and logistic regression analyses were used to assess relationships among combustible tobacco and cannabis use.ResultsPast 30-day cannabis use was somewhat higher among current tobacco (or cigarette) smokers (n=57/987=5.8%) than among former or never smokers (n=10/288=3.5% and n=6/316=1.9%, respectively). Joints were the most commonly used form of cannabis use for both current cigarette smokers (96.9%) and non-smokers (76.5%). Among those who smoked cannabis joints, 95% current smokers and 67% of non-smokers reported that they ‘always’ roll cannabis with tobacco.ConclusionsIn this Netherlands-based sample, most cannabis was reported to be consumed via smoking joints, most often mixed with tobacco. This behaviour may present unique health concerns for non-cigarette smoking cannabis users, since tobacco use could lead to nicotine dependence. Moreover, many non-cigarette smoking cannabis users appear to be misclassified as to their actual tobacco/nicotine exposure.


2020 ◽  
Vol 35 (7) ◽  
pp. 1693-1701 ◽  
Author(s):  
Stine Agergaard Holmboe ◽  
Lærke Priskorn ◽  
Tina Kold Jensen ◽  
Niels Erik Skakkebaek ◽  
Anna-Maria Andersson ◽  
...  

Abstract STUDY QUESTION Are use of e-cigarettes and snuff associated with testicular function as previously shown for conventional cigarettes and marijuana? SUMMARY ANSWER Use of e-cigarettes is associated with reduced semen quality but not with higher serum testosterone level as observed for conventional cigarette use. Snuff use was not associated with markers of testicular function. WHAT IS KNOWN ALREADY Cigarette smoking has previously been associated with higher testosterone levels and impaired semen quality, whereas it is unresolved whether use of e-cigarettes or snuff influence the testicular function. STUDY DESIGN, SIZE, DURATION This cross-sectional population-based study included 2008 men with information on cigarette and marijuana use (enrolled between 2012 and 2018), among whom 1221 men also had information on e-cigarette and snuff use (enrolled between 2015 and 2018). PARTICIPANTS/MATERIALS, SETTING, METHODS Men (median age 19.0 years) from the general population provided a semen and blood sample and filled out a questionnaire on lifestyle including information on smoking behaviour. Associations between different types of smoking (e-cigarettes, snuff, marijuana and cigarettes) and reproductive hormones (total and free testosterone, sex hormone-binding globulin, LH, oestradiol and ratios of inhibin B/FSH, testosterone/LH and free testosterone/LH) and semen parameters (total sperm count and sperm concentration) were examined using multiple linear regression analyses adjusted for relevant confounders. MAIN RESULTS AND THE ROLE OF CHANCE Approximately half of the men (52%) were cigarette smokers, 13% used e-cigarettes, 25% used snuff and 33% used marijuana. Users of e-cigarettes and marijuana were often also cigarette smokers. Compared to non-users, daily e-cigarette users had significantly lower total sperm count (147 million vs 91 million) as did daily cigarette smokers (139 million vs 103 million), in adjusted analyses. Furthermore, significantly higher total and free testosterone levels were seen in cigarette smoking men (6.2% and 4.1% higher total testosterone and 6.2% and 6.2% higher free testosterone in daily smokers and occasional smokers, respectively, compared to non-smoking men), but not among e-cigarette users. Daily users of marijuana had 8.3% higher total testosterone levels compared to non-users. No associations were observed for snuff in relation to markers of testicular function. LIMITATIONS, REASONS FOR CAUTION We cannot exclude that our results can be influenced by residual confounding by behavioural factors not adjusted for. The number of daily e-cigarette users was limited and findings should be replicated in other studies. WIDER IMPLICATIONS OF THE FINDINGS This is the first human study to indicate that not only cigarette smoking but also use of e-cigarettes is associated with lower sperm counts. This could be important knowledge for men trying to achieve a pregnancy, as e-cigarettes are often considered to be less harmful than conventional cigarette smoking. STUDY FUNDING/COMPETING INTEREST(S) Funding was received from the Danish Ministry of Health (1-1010-308/59), the Independent Research Fund Denmark (8020-00218B), ReproUnion (20200407) and the Research Fund of the Capital Region of Denmark (A6176). The authors have nothing to disclose. TRIAL REGISTRATION NUMBER NA


2021 ◽  
Author(s):  
Loren Kock ◽  
Lion Shahab ◽  
Ilze Bogdanovica ◽  
Jamie Brown

Abstract Introduction: In May 2020 the EU Tobacco Products Directive (TPD) ban on the sale of menthol cigarettes was implemented after a four-year transitional period. This study examined the prevalence of menthol cigarette smoking in the months following the ban, and according to sociodemographic and smoking characteristics.Methods: Cross-sectional data came from a representative survey of current smokers (18+) in England (unweighted n=1,577) during seven months (July-January) in 2020/2021. The weighted prevalence of menthol cigarette smoking as a proportion of total cigarette smoking was calculated, and chi-squared statistics assessed the relationship between menthol smoking, sociodemographic and smoking characteristics. Sources of purchase of menthol cigarettes were also explored.Results: The proportion of current smokers who smoked menthol cigarettes was similar in July to October 2020 (17.5%, 95% CI 15.3%-20.1%) compared with November 2020 to January 2021 (16.3%, 95% CI 13.9%-19.2%) (χ2(1)=0.38, P=0.56)). Menthol cigarette smoking was more common among younger age groups (16-24 = 29.0%; 25-34 = 23.3%) and women (21.1%). Menthol cigarette smokers showed lower cigarette dependence compared with other cigarette smokers. Purchases of menthol cigarettes from any illicit source in the past six months declined from 34.5% in July-October 2020 to 19.0% in November 2020–January 2021.Conclusions: A substantial proportion (just under a fifth) of current smokers in England reported menthol cigarette smoking between July-January 2020/2021 despite the ban. There was no decline in this proportion across the period, suggesting that smokers mitigated the impact of the ban by a variety of means, such as with legal menthol accessories.


2018 ◽  
Vol 1 (1) ◽  
pp. 1 ◽  
Author(s):  
Aljoharah Mohammed Algabbani ◽  
Rasha Almubark ◽  
Nora Althumiri ◽  
Amani Alqahtani ◽  
Nasser BinDhim

Background Tobacco smoke is the second leading risk factor for death worldwide. This report aims to determine the recent prevalence of and factors associated with cigarette smoking in Saudi Arabia. Methods Data were pooled from two nationwide cross-sectional surveys conducted in 2018 across the 13 regions of Saudi Arabia. The study targeted Arabic-speaking Saudi residents aged 18 years or older between March and July 2018. Results A total of 7,317 adults across the 13 regions of Saudi Arabia were included in this study. The prevalence of cigarette smoking was 21.4% of the population. The prevalence of smoking was 32.5% among males and 3.9% among females. There is a disparity in cigarette smoking prevalence from one region to another. The Aljwaf, Northen Borders, Riyadh, and Eastern regions have the highest prevalence, while the fewest cigarette smokers live in Aseer Jizan and Albaha. Conclusion The prevalence of cigarette smoking was relatively high among males, those aged 25–44 year old, and those who live in the northern regions.


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