scholarly journals A Hospital Based Observational Study on Diagnostic Role of High-Resolution Ultrasound and Doppler Imaging in Evaluation of Non-Thyroidal Neck Masses of Patients Attending the Department of Radiodiagnosis, AMCH, Dibrugarh with FineNeedle Aspiration / Histopathological Correlation

2021 ◽  
Vol 8 (11) ◽  
pp. 597-602
Author(s):  
Kallol Prasad Das ◽  
Pronami Borah ◽  
Mondita Borgohain ◽  
Rudra Kanta Gogoi ◽  
Raamseena N.A.
Keyword(s):  
Lymph Node ◽  
High Resolution ◽  
Lymph Nodes ◽  
Adult Population ◽  
Cervical Lymphadenopathy ◽  
Doppler Imaging ◽  
Neck Swelling ◽  
Colour Doppler ◽  
Female Ratio ◽  
Study Results

BACKGROUND Neck swellings consists of a wide spectrum of pathological entities. These swelling can occur due to a variety of aetiologies consisting of congenital, acquired inflammatory, neoplastic, or vascular origin. It is essential to have an extensive knowledge of the anatomy and contents of each cervical compartment to achieve a diagnosis. The age of presentation and clinical findings often narrows down the differential diagnosis. Ultrasonography (USG) is helpful in differentiating the nature of the lesions and differentiating solid from cystic neck lesions. Ultrasound is often used as an initial modality for pre-treatment assessment of any neck swelling. METHODS Patients with clinically palpable / non-palpable neck swellings were scanned using 7.5 - 11 MHz transducers, excluding patients with diagnosed thyroid swellings. RESULTS In total 120 cases were studied; the mean age of patients was 34 years with a male to female ratio of 1.1:1. The age wise categorisation included paediatric population (34.2 %) and adult population (65.8 %). 96 (80 %) cases presented with painless neck swelling, 76 (63.3 %) cases were non-neoplastic and 44 (36.7 %) cases were neoplastic in nature. Cervical lymphadenopathy being the most common ultrasound finding in both paediatric and adult population. Malignant lesions were most common in adult age group. Heterogeneous echotexture, rounded nodes, intranodal necrosis, loss of echogenic hila, peripheral nodal blood flow and increased pulsatility index (PI) and resistive index (RI) were important features of malignant lymph nodes. Sensitivity and specificity of USG and Doppler in differentiating neoplastic from non-neoplastic lesions were 97.7 % and 98.3 % respectively and for differentiating benign from metastatic nodes were 97.7 % and 98.3 % respectively. CONCLUSIONS Considering the study results and observations, USG is the best initial investigation for the evaluation of inflammatory, cystic and neoplastic swellings in various age groups. It is non-invasive, cost effective readily available and repeatable technique. It is relatively easier to use and does not involve radiation hazards. Colour Doppler can evaluate the vascularity of the lesions and provide details of any vascular invasion of metastatic lesions. Ultrasound can differentiate aetiology of lymph node enlargement to a significant extent. KEYWORDS High Resolution Ultrasound, Paediatric Neck Mass, Metastatic Lymph Node, Histopathology, FNAC, Tubercular Lymph Nodes, Colour Doppler, Non-Thyroidal

scholarly journals Histomorphological Pattern of Cervical Lymphadenopathy

2013 ◽  
Vol 3 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Md Atiqur Rahman ◽  
Md Mamun Ali Biswas ◽  
Syeda Tasfia Siddika ◽  
Abdul Mannan Sikder
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Hodgkin Lymphoma ◽  
Cervical Lymphadenopathy ◽  
Histological Evaluation ◽  
Cervical Lymph Nodes ◽  
Female Ratio ◽  
Study Results ◽  
Metastatic Neoplasm ◽  
Age And Sex

Background: Enlarged palpable cervical lymph nodes as a primary presenting sign are very common and may be due to inflammatory lesions and tumors. Correlation between clinical findings and laboratory data is essential in arriving at a diagnosis. In patients presenting with cervical lymphadenopathy, excision biopsy provides material to establish an early diagnosis. We designed this study in our population for histological evaluation of cervical lymph node biopsies that might be important in the management of these patients. Objective: Histopathological evaluation of different diseases involving the cervical lymph nodes in relation to age and sex of the study population. Materials and Methods: It was a cross sectional study conducted in the department of Pathology, Enam Medical College & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. A total of 107 patients were evaluated for specific cause of cervical lymphadenopathy in relation to age and sex. Lymph node biopsies of all patients of both sexes and all age groups were included in the study. Results: Among the 107 subjects 58 (54.2%) were males and 49 (45.8%) were females with a male to female ratio of 1.2:1. The age of the patients ranged from 2 to 85 years with a mean age of 32.68 ± 18.01 years. Of the 107 lymph node biopsies, 34 cases (31.8%) were reactive lymphadenitis, 41 cases (38.3%) were tuberculosis, 2 cases (1.9%) were non-caseous granuloma, 6 cases (5.6%) were Hodgkin lymphoma, 8 cases (7.5%) were non-Hodgkin lymphoma, 12 cases (11.2%) were metastatic neoplasm and 4 cases (3.7%) were other specific lesions. Conclusion: The commonest cause of cervical lymphadenopathy was tuberculosis, followed by reactive lymphadenitis, lymphoma and metastatic neoplasm. DOI: http://dx.doi.org/10.3329/jemc.v3i1.13837 J Enam Med Col 2013; 3(1): 13-17

scholarly journals Evaluation of Ultrasonography and Colour Doppler in Cervical Lymphadenopathy Taking Histopathology as Comparison

2021 ◽  
Vol 10 (19) ◽  
pp. 1391-1397
Author(s):  
Prinson George ◽  
Aria Jyothi Appukuttan
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Sensitivity And Specificity ◽  
Predictive Value ◽  
Imaging Modality ◽  
Cervical Lymphadenopathy ◽  
Colour Doppler ◽  
Likelihood Ratios ◽  
Cervical Lymph Nodes ◽  
Grey Scale

BACKGROUND Grey scale ultrasonography can be used as a first line imaging modality along with histopathology for evaluation of cervical lymphadenopathy. Morphologic features like size, shape, hilum and necrosis within the lymph node and vascularity are analysed. We wanted to identify the role of Grey scale ultrasonography and colour Doppler in characterisation of enlarged cervical lymph nodes, evaluate findings in benign and malignant cervical lymphadenopathy and assess the sensitivity, specificity, predictive value, likelihood ratios and accuracy in malignant and benign cervical lymph node enlargement. METHODS This was a cross sectional study with diagnostic test evaluation. All suspected cases of cervical lymphadenopathy referred for sonological evaluation to the Department of Radiodiagnosis of Govt. T.D. Medical College, Alappuzha were included in the study. About 75 patients included in the study, underwent Grey scale and colour Doppler sonography of cervical lymphadenopathy. RESULTS When three criteria were positive for malignancy, the sensitivity and specificity of grey scale ultrasonography and colour Doppler were 100 % and 73.80 %, and when four criteria were positive, the sensitivity and specificity were 72.73 %, and 90.48 % respectively. When we analysed individual variables, status of hilum (absence / presence) has reasonably good sensitivity and specificity, positive predictive value, negative predictive value and accuracy (90.09 %, 92.90 %, 90.09 %, 92.90 % and 92.0 % respectively). In our study the important criteria positive for malignant lymph nodes were size > / 11 mm in short axis diameter, round shape, absent hilum and peripheral and central + peripheral type of vascularity of cervical lymph nodes. For benign lymph nodes, oval shape, presence of hilum and central vascularity were the important criteria noted. CONCLUSIONS Grey scale ultrasonography can be complemented by colour Doppler ultrasonography (USG) in patients presenting with cervical lymphadenopathy to differentiate between benign and malignant lesions by reducing unnecessary biopsies by more accurate discrimination. KEY WORDS Grey Scale Ultrasonography, Malignant, Benign Lymph Nodes, Histopathology

scholarly journals ULTRASONOGRAPHIC EVALUATION;

2012 ◽  
Vol 19 (06) ◽  
pp. 890-893
Author(s):  
EJAZ HUSSAIN SIDDIQUI ◽  
SAAD SIDDIQUI ◽  
Ghulam RASOOL ◽  
Noreen Shah
Keyword(s):  
Multinodular Goiter ◽  
Pediatric Population ◽  
Cervical Lymphadenopathy ◽  
Ultrasound Finding ◽  
Neck Swelling ◽  
Female Ratio ◽  
Neck Masses ◽  
Adult Females ◽  
Study Results ◽  
Ultrasound Findings

Objectives: To assess common presenting complaints and the role of ultrasound in evaluating neck masses in pediatric andadult population. Design: Cross sectional. Setting: Khyber X-Ray, 7 Khyber Medical Centre, Dabgari Gardens, Peshawar. Period: July 2011to December 2011. Material and Methods: Data from patients presenting for evaluation of a neck mass was analyzed for presentingcomplaints and ultrasound findings according to objectives of the study. Results: In total 105 cases were included in the study. The mean ageof patients was 36.8 years with a male to female ratio of 1:2.1. The age wise categorization included pediatric population (10.5%) adultpopulation (89.5%). Both painful and painless neck swellings were common presenting complaints in pediatric population with cervicallymphadenopathy being the most common ultrasound finding. Among Adult males painless neck swelling was the most common presentingcomplaint with cervical lymphadenopathy followed by Multinodular goiter being most common ultrasound findings. Most common presentingcomplaint in Adult females was painless neck swelling with Multinodular goiter being most common ultrasound finding. Conclusions: NeckMasses are commonly encountered in all age groups especially pediatric population and adult females, Ultrasound is a useful and safemodality in evaluation of neck masses.

Detection of normal mediastinal lymph nodes by ultrasonography

1997 ◽  
Vol 38 (6) ◽  
pp. 965-969 ◽  
Author(s):  
C. F. Dietrich ◽  
M. Liesen ◽  
R. Buhl ◽  
G. Herrmann ◽  
J. Kirchner ◽  
...  
Keyword(s):  
High Resolution ◽  
Lymph Nodes ◽  
Pathological Finding ◽  
Doppler Imaging ◽  
Colour Doppler Imaging ◽  
Asymptomatic Volunteers ◽  
Human Cadavers ◽  
Mean Size ◽  
Almost All ◽  
Node Diameter

Purpose: the detection by US (ín contrast to CT) of lymph nodes of any size in the mediastinum is usually considered to be a pathological finding. the aim of this study was to find out whether it was possible to detect normal lymph nodes by high-resolution mediastinal US Material and Methods: Six different mediastinal regions in 80 healthy asymptomatic volunteers and in 20 human cadavers were examined by means of US (with colour Doppler imaging) to assess US access to the respective regions and to demonstrate the number and size of detectable lymph nodes. All the cadaveric lymph nodes that were detected were examined histologically to exclude inflammatory or malignant infiltration Results: in almost all subjects, we obtained US access to the supra-aortic (100%), paratracheal (95%), prevascular (99%), and pencardial (98%) regions, and to the aorticopulmonary window (98%). US access to the subcarinal region was more difficult (75%). in the healthy subjects, lymph nodes were detected in the paratracheal region (in 35% of these subjects, mean lymph-node diameter 12×7 mm), in the aorticopulmonary window (45%, 14×8 mm), and in the subcarinal region (13%, 13×7 mm). in the cadavers, histologically normal lymph nodes were detected frequently in the paratracheal region (85%, mean size 11×6 mm) and in the aorticopulmonary window (90%, 11×5 mm) Conclusion: These results indicate that normal lymph nodes (and not only pathological lymph nodes) can be demonstrated by high-resolution mediastinal US

scholarly journals Frequency of Lympnode Metastasis in Supraglottic Ca Larynx

2019 ◽  
Vol 31 (2) ◽  
pp. 72-75
Author(s):  
Mohammad Rokan Uddin Bhuiyan ◽  
Mohammad Idris Ali ◽  
Balayet Hossain Siddiquee ◽  
Fatema Johora ◽  
Mohammad Kamal Hossain
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cervical Lymphadenopathy ◽  
Female Ratio ◽  
Node Metastasis ◽  
T Stage ◽  
Supraglottic Carcinoma ◽  
Level Ii ◽  
Number Of Patients ◽  
Carcinoma Of Larynx

Introduction: To observe the association between the level of lymph node metastasis and the T- stage and to evaluate the N- stage in supraglottic carcinoma of larynx. Materials and Methods: A prospective cross-sectional study was carried out on 80 consecutive cases of supraglottic carcinoma larynx in three tertiary level hospital in Dhaka during July'2009 to March 2011. Results: The highest number of patients were in the age group 5th and 6th decades. Male to female ratio was 9:1. Topographically 70 cases (87.5%) had lesions involving epiglottis, 5 cases (6.25%) in aryepiglottic fold and 5 cases (6.25%) had lesions at false cord. Majority cases were histopathologically confirmed squamous cell carcinoma (95%) and among them 46 cases (57.5%) had well differentiated. Cervical metastatic lymph nodes were found 40% (32 cases) where level-II was most common. This was most frequent in early supraglottic(T1&T2) carcinoma of larynx (86.25%), P=0.008. A positive correlation was found between the T stage of primary tumours and frequency of cervical lymphadenopathy. Lymph node metastasis were 4.77% in T1, 37.50% in T2, 71.43% in T3 and 91.67% in T4. In early stage lymph node involved 93.75% in Level- II, 6.25% in Level- III & in advanced stage 100% in Level - II, 62.5% in Level - III and 25.0% in Level - IV. Distribution of study cases (31.25%) in stage-II, 25% in stage-I, 22.50% in stage-Ill and 21.25% were in stage-IV. Conclusion: Result of this study may help the clinician for planning of treatment of this malignant diseases as well awareness. Medicine Today 2019 Vol.31(2): 72-75

scholarly journals Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

2012 ◽  
Vol 2 (1) ◽  
pp. 8-14
Author(s):  
Md Atiqur Rahman ◽  
Md Mamun Ali Biswas ◽  
Syeda Tasfia Siddika ◽  
Abdul Mannan Sikder
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Hodgkin Lymphoma ◽  
Histopathological Examination ◽  
Age Groups ◽  
The Body ◽  
Cross Sectional ◽  
Cervical Lymph Nodes ◽  
Female Ratio ◽  
Histopathological Evaluation

Background: Lymphadenopathy is a common manifestation of a large variety of disorders,both benign and malignant. It is essential to define the pattern of disorders presenting primarily as lymph node enlargement in a particular environment. Histopathological examination of the lymph node biopsies is a gold standard test in the distinction between reactive and malignant lymphoid proliferations as well as for detailed subtyping oflymphomas. We designed this study in our population for histopathological evaluation of lymph nodes that might be helpful for clinical management of these lesions. Objective: Histopathological evaluation of lymphadenopathy from excised specimen, in relation to ageand sex of the patients, and distribution of the lymph nodes. Materials and Methods: It was a retrospective cross sectional study conducted in the department of Pathology, Enam MedicalCollege & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. Lymph node biopsies of all patients of both sexes and all age groups were included.Metastatic lymph nodes associated with evidence of primaries elsewhere in the body were excluded from the study. Total 191 lymph node biopsies were selected for histopathological evaluation. Among these 90 (47.12%) were from males and 101 (52.88%) were from females with male to female ratio being 1:2.1. The age of the patients ranged from 2 to 85 years with a mean age of 35.73 ± 18 years. Results: Cervical lymph nodes were the most common (56%) biopsied group. Of the 191 cases 59 cases (30.89%) were reactive lymphadenitis, 64 cases (33.5%) were tuberculosis, 2 cases (1.05%) were non-caseous granuloma, 11 cases (5.76%) were Hodgkin lymphoma, 22 cases (11.52%) were non-Hodgkin lymphoma, 24 cases (12.57%) were metastatic neoplasm and 9 cases (4.7%) were other lesions.Conclusion: Tuberculosis was the most common cause of lymphadenopathy, followed by reactive lymphadenitis and the cervical group of lymph nodes was most frequently affected. DOI: http://dx.doi.org/10.3329/jemc.v2i1.11915 J Enam Med Col 2012; 2(1):8 -14

scholarly journals Rosai Dorfman Disease

1970 ◽  
Vol 8 (1) ◽  
pp. 28-31
Author(s):  
Md Faizul Islam Chowdhury ◽  
MA Kashem Khandaker ◽  
Hossain M Zaid ◽  
Hazera Khatun ◽  
Md Murad Hossain ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Blood Count ◽  
Lymph Node Biopsy ◽  
Full Blood Count ◽  
Not Given ◽  
Neck Swelling ◽  
Node Biopsy ◽  
Rosai Dorfman Disease

Mr. Shahinoor an 18 year old male got himself admitted at DMCH in July,2007 with the complaints of bilateral neck swelling and fever for 1 month. The enlarged lymph nodes were clustered in cervical regions involving both anterior and posterior chains and largest one measuring 5 cm×2.5 cm.He was otherwise healthy on examination. Full blood count showed neutrophil leukocytosis and raised ESR.Sputum for AFB was found negative and xray chest was normal. FNA of lymph node showed non specific lymphadenitis with reactive hyperplasis. Lymph node biopsy was done and histopathology revealed Rosai Dorfman Disease, a very rare yet fascinating disorder also called Sinus Histiocytosis with Massive Lymphadenopathy.It is a benign proliferative disorder of the histiocytes. He was not given any tretament and is under follow up.   DOI = 10.3329/jom.v8i1.1376 J MEDICINE 2007; 8 : 28-31

scholarly journals A Comparative Study of Cytomorphological Patterns of Lymph Node Aspirates in Paediatric and Adult Populations

2020 ◽  
Author(s):  
M Dedeepya ◽  
AS Ramaswamy ◽  
BN Kumarguru ◽  
M Udaya Kumar
Keyword(s):  
Lymph Node ◽  
Adult Population ◽  
Tertiary Care ◽  
Paediatric Population ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Chi Square ◽  
Statistical Tool ◽  
Diagnostic Efficacy ◽  
Study Results

Introduction: Lymphadenopathy is one of the most common clinical presentations of patients. Lymph node is a commonly aspirated organ for diagnostic purposes. Fine Needle Aspiration Cytology (FNAC) of lymph node has become an integral part of initial diagnosis and management. Aim: To compare the cytomorphological patterns of the lymph node lesions in the paediatric population with that of the adult population and to correlate with the available histopathological diagnosis. Materials and Methods: It was a retrospective observational study of lymph node lesions conducted at a rural tertiary care referral institute, PES Institute of Medical Sciences and Research (PESIMSR), Kuppam, Andhra Pradesh, India, from January 2017 to June 2018 for a period of 18 months. Cytology smears were retrieved, reviewed and analysed. Cytological diagnosis was compared with available histopathological diagnosis and concordance was calculated. Chi-square test was the statistical tool used to analyse the data in the study. Results: Two hundred and seventy four cases were analysed. Adult population constituted 225 cases (82.12%). Paediatric population constituted 49 cases (17.88%). Reactive lymphadenitis was the commonest pattern in both the groups. Chronic lymphoproliferative lesions {4 cases (1.7%)} constituted the least common lesion in adults and mycobacterial lymphadenitis {1 case (2.04%)} constituted the least common lesion in paediatric population. Conclusion: Distribution of cytological patterns of lymph node lesions in paediatric and adult populations are different and are found to be statistically significant. Cytological evaluation of lymph node lesions has a high diagnostic efficacy for the diagnosis of neoplastic lesions.

scholarly journals High Resolution Sonography in Diagnosis of Metastatic Cervical Lymph Nodes in Oral Squamous Cell Carcinoma

1970 ◽  
Vol 28 (2) ◽  
pp. 92-99
Author(s):  
SM Anwar Sadat ◽  
Rufia Nasrin Rita ◽  
Asad-Uz Zaman ◽  
Md Abdur Rob ◽  
Md Musharraf Husain ◽  
...  
Keyword(s):  
Lymph Node ◽  
High Resolution ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Maxillofacial Surgery ◽  
Cost Effective ◽  
Cervical Lymph Nodes ◽  
Non Invasive ◽  
Sensitivity Specificity

Ultrasound is reported superior to clinical palpation fordetecting lymph nodes and metastasis. The advantage ofultrasound over other imaging modalities is price, lowpatient burden, and possibilities for follow up. A crosssectional Study on 29 cases of oral squamous cell carcinomawas done in Department of Oral & Maxillofacial Surgery,Dhaka Dental College & Hospital, Dhaka from January2006 to December 2007. The sensitivity, specificity, positivepredictive value, negative predictive value & Accuracy ofUltrasonographic technique for determining metastaticcervical lymph node were 93.33%, 50%, 66.7%, 87.5% and72.4% respectively. Considering the finding of the study,Sonographic evaluation can improve the diagnosis ofmetastatic cervical lymph node in patients with oralsquamous cell carcinoma. It is cost effective, non-invasive,less burden to patient, does not create problem ofoverlapping with mandible and can be done repeatedly tofollow up. Therefore, high resolution sonography may bean adjunct tool in diagnosing metastatic nodes in patientswith oral squamous cell carcinoma.DOI: 10.3329/jbcps.v28i2.5369J Bangladesh Coll Phys Surg 2010; 28: 92-99

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