A Prospective Study of Patients with Pseudoexfoliation Glaucoma and Its Management in a Tertiary Care Centre in South India

2021 ◽  
Vol 8 (31) ◽  
pp. 2848-2854
Author(s):  
Nishat Sultana ◽  
Priyam Gupta
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Medical Therapy ◽  
Tertiary Care ◽  
Pseudoexfoliation Syndrome ◽  
Age Group ◽  
Care Centre ◽  
Pseudoexfoliation Glaucoma ◽  
Tertiary Care Centre ◽  
Optic Nerve Damage

BACKGROUND Pseudoexfoliation syndrome is the most common identifiable cause of open angle glaucoma worldwide. Pseudoexfoliation glaucoma develops in 50 % of patients with pseudoexfoliation syndrome. The purpose of this study was to assess the clinical profile, intraocular pressure (IOP), gonioscopic findings, disc changes and need for medical or surgical line of management for the control of pseudoexfoliation glaucoma. METHODS It was a prospective hospital based interventional study of 68 consecutive patients diagnosed with pseudoexfoliation glaucoma, who presented to the glaucoma clinic at a tertiary care centre from Nov 2017 to Mar 2019. RESULTS 68 patients diagnosed with pseudoexfoliation glaucoma were evaluated during the study period from November 2017 to March 2019. Male predominance of 43 (63 %) was noticed. Mean age group of study population was 68 years with 44 (65 %) of patients in age group of 61 – 75 years. 55 cases had bilateral pseudoexfoliation. 85 (69 %) eyes had a pressure of > 21 mm of Hg. 97 (79 %) eyes had open angles, 4 (3 %) occludable angles, 22 (18 %) had closed angles. 4 (3 %) of eyes had cup disc ratio < 0.5, 49 (40 %) eyes had cup disc ratio of 0.5 - 0.7, 64 (52 %) had > 0.7 cupping. 38 (31 %) eyes were controlled on medical therapy with topical antiglaucoma medications. In 14 (11 %), eyes were treated with Nd: YAG PI (neodymium-doped yttrium aluminium garnet peripheral laser iridotomy) with medical treatment, 59 (48 %) eyes were taken up for triple procedure. 10 (8 %) eyes could not be controlled using medical therapy and had to be taken for surgical treatment. CONCLUSIONS Pseudoexfoliation glaucoma leads to irreversible visual loss if high IOP is not treated leading to glaucomatous optic nerve damage and visual field loss. The response to medical therapy is poor and needs surgical intervention. KEYWORDS Pseudoexfoliation Glaucoma, Intraocular Pressure, Optic Nerve Damage, Dandruff Like Material

scholarly journals OCULAR CLINICAL PROFILE OF PATIENTS WITH PSEUDOEXFOLIATION SYNDROME AND PSEUDOEXFOLIATION GLAUCOMA AT TERTIARY CARE CENTRE IN KASHMIR

2021 ◽  
Vol 9 (12) ◽  
pp. 261-269
Author(s):  
Jasiya Bashir ◽  
◽  
Ejaz Akbar Wani ◽  
Keyword(s):  
Optic Nerve ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Tertiary Care ◽  
Nerve Damage ◽  
Clinical Profile ◽  
Care Centre ◽  
Pseudoexfoliation Glaucoma ◽  
Tertiary Care Centre ◽  
Optic Nerve Damage

Aim: To study the clinical profile of pseudoexfoliation (PEX) syndrome and Pseudoexfoliation glaucoma at tertiary care centre in Kashmir. Materials and Methods: A cross sectional study consisting of 100 PEX and 100 PEXG patiens, attending the general ophthalmology clinic of a tertiary care center in kashmir. All patients underwent a complete ophthalmologic evaluation including recording IOP,gonioscopy and Central Corneal Thickness(CCT). Results: The study cohort comprised 200 patients(100 with PEX and 100 with PEXG). There were 145(72.5) males and 55(27.5%) females. The highest number of patients (120 patients) were from the age group between 61 and 70years. 145(72.5%) patients were involved in outdoor activities.153(76.5%) patients had bilateral involvement of pseudoexfoliationand pseudoexfoliative material was present at anterior lens capsule in 175(49.58%) eyes. Nuclear cataract was predominant type of cataract and was present in 188(48.2%)eyes. Mean IOP was 17.26±7.634mmHg in PEX group and 24.39±4.456mmHg in PEXG group. Gonioscopyshowed open angles in 96.5% of eyes and occludable in 3.5% eyes . Mean central corneal thickness was 531.80±19.127μm. Conclusion: The prevalence of PEX is found to increase with age. Patients with PXG had more severity of optic nerve damage at presentation. Therefore a careful assessment for detection of PEX is warranted and regular follow-up of patients is desired to minimize the extent of optic nerve damage.

scholarly journals Detection and Enumeration of the Commonest Stool Parasites Seen in a Tertiary Care Center in South India

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Vani Chandrashekar
Keyword(s):  
Entamoeba Histolytica ◽  
South India ◽  
Care Center ◽  
Tertiary Care ◽  
Age Group ◽  
Tertiary Care Center ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Stool Samples

The aim of this study was to identify common stool parasites in patients attending a tertiary care centre in South India. We evaluated 2355 stool samples and parasites were detected in 7.9% of samples. 41.1% of our patients were in the 45–58-year age group. Protozoal infections were the commonest seen in 7.8% of samples. Entamoeba histolytica was the commonest protozoa (4.6%) followed by Entamoeba coli (1.2%) and Giardia (0.8%). Entamoeba histolytica and Entamoeba coli were together seen in 0.63%, and they were the commonest organisms seen in samples with multiple-organism infection. Both were equally detected in diarrheal samples.

scholarly journals Pattern of Ear Diseases among Paediatric ENT Patient: An Experience from Tertiary Care Centre, Pokhara, Nepal

2012 ◽  
Vol 32 (2) ◽  
pp. 142-145 ◽  
Author(s):  
B Sigdel ◽  
R Nepali
Keyword(s):  
Tertiary Care ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Suppurative Otitis Media ◽  
Ear Diseases ◽  
Paediatric Age ◽  
One Year ◽  
A Prospective Study ◽  
Nose And Throat

Introduction: Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases. J. Nepal Paediatr. Soc. 32(2) 2012 142-145 doi: http://dx.doi.org/10.3126/jnps.v32i2.5673

TO DETERMINE THE PREVALENCE AND OCCURANCE OF VISUAL MORBIDITY IN PATIENTS OF PTERYGIUM ATTENDING EYE OPD IN A TERTIARY CARE CENTRE OF EASTERN INDIA

2021 ◽  
pp. 80-81
Author(s):  
Vandana Parasar ◽  
Vidyabhushan Kumar ◽  
Ankita Singh ◽  
Nilesh Mohan
Keyword(s):  
Socioeconomic Status ◽  
Tertiary Care ◽  
Living Condition ◽  
Age Group ◽  
Care Centre ◽  
Eastern India ◽  
Tertiary Care Centre ◽  
Male Preponderance ◽  
Uvb Exposure ◽  
Epidemiological Trends

To determine the prevalence and occurrence of visual morbidity in patients of pterygium attending eye opd in a tertiary care centre of Bihar. Methods: In this observational study a total of 193 patients, diagnosed with pterygium, underwent complete ocular examination by an ophthalmologist. Epidemiological trends including age, sex, occupation, effect of living condition and socioeconomic status were analyzed. Results: There is a male preponderance of 58.03%. The age incidence of the group showed that the incidence of pterygium was 10.36% in the age group of less than 30 years. It rises to a maximum of 29.53% in the age of 41-50 years and then gradually declines.. The incidence was found to be maximum among farmers(39.86%) followed by miners(31%). Conclusion: People who work outdoors are at a greater risk because they are subjected to involuntary UVB exposure. The highest exposure occurs during the two hours on either side of noon. Workers must be aware and should take appropriate measures like wearing protective glasses, caps, etc

scholarly journals CLINICAL PROFILE OF INTUSSUSCEPTION IN CHILDREN ADMITTED TO A TERTIARY CARE CENTRE IN KERALA

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Neethu Jose ◽  
Aparna Namboodiripad ◽  
Regi George A N
Keyword(s):  
Tertiary Care ◽  
Spontaneous Resolution ◽  
Reduction Technique ◽  
Clinical Profile ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Hydrostatic Reduction ◽  
Duration Of Hospital Stay ◽  
Study Population

Background and objectives: Intussusception is the commonest cause of bowel obstruction and is one of the common abdominal emergencies in children younger than 2 years of age.The objective of the study was to assess the clinical profile of intussusception in children and the management and the outcome  and  to assess whether the characteristics mentioned in clinical profile are predictive of subsequent management and outcome of the disease. Methods: A hospital based descriptive study conducted in a tertiary care centre in Kerala, using purposive sampling technique. 120 children admitted with diagnosis of intussusception   fulfilling inclusion criteria and whose parents consented for study were included in the study population, during the study period from November 2018 to June 2020. Detailed history, clinical examination including per rectal examination  and USG was done to make diagnosis of intussusception in suspected cases. Follow up is done at 72 hours,1 week after the admission and 1month later. To assess the clinical profile and outcome of patients, frequency and percentage is used. To obtain the association of clinical profile with outcome chi square test is applied. Results: Outcome of the problem was correlated with age, sex, symptoms, risk factors sonological findings treatment protocol and duration of hospital stay. Out of the 120 children in study population, majority were males(65.8%) with male to female ratio 1.9:1 and majority was in the age group 7- 12 months, which is similar to many other similar studies. Maximum number of cases were in the month of February(14.2%) and November(15%).  Majority of the patients(57.5%) presented to healthcare facility within 24 hours of onset of first symptom.Irritability was the most common clinical symptom(62.5%) followed by vomiting(58.3%) and abdominal pain(49.2%). Ileocolic intussusception (96.7%) was the commonest type. Majority of the cases could be managed with hydrostatic saline reduction(73.3%) and significantly lesser number of patient went for surgical intervention(7.5%) and spontaneous resolution(19.2%). Conclusions: Incidence of intussusception is more common among males and more in the 7-12 month age group.  Majority of the cases presented to health care facility within 24 hours of onset of symptom and could be managed with hydrostatic reduction technique and had a shorter duration of hospital stay compared to surgical reduction technique. Even recurrent cases could be managed with hydrostatic saline reduction. Keywords: Intussusception;  Intestinal obstruction;  Hydrostatic reduction; Spontaneous resolution

scholarly journals Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre

2016 ◽  
Vol 2 (4) ◽  
pp. 86
Author(s):  
Rangaraj Murugaiyan
Keyword(s):  
Tertiary Care ◽  
Significant Proportion ◽  
Clinical Spectrum ◽  
Age Group ◽  
Care Centre ◽  
Inclusion Criteria ◽  
Common Site ◽  
Tertiary Care Centre ◽  
Exclusion Criteria ◽  
The Past

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Childhood vitiligo is a special subtype and is seen in significant proportion of vitiligo patients. There are only a few clinical studies in the past which address the clinical spectrum of vitiligo in children. This study on eighty cases of childhood vitiligo will cover the epidemiology and clinical spectrum.</span></p><p class="abstract"><strong>Methods:</strong> To study the epidemiology, clinical spectrum and associations in childhood vitiligo. Inclusion criteria: all new cases of vitiligo in children under 12 years attending the outpatient department of Dermatology, exclusion criteria: old treated cases of vitiligo and age more than 12 years. Statistical analysis was done using mean and percentage of means.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Most common age group affected includes 4-6 years. Most common site of initial lesion was head and neck followed by upper limb, lower limb and trunk. Most common clinical type was vitiligo vulgaris followed by focal type then segmental. Lip tip type was least common type. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Childhood vitiligo is a serious issue and the knowledge of its various patterns and associations needs to be updated at regular intervals.</span></p>

scholarly journals Lower Genital Tract Trauma in a Tertiary Care Centre in Mid-Western Nepal

2017 ◽  
Vol 56 (205) ◽  
pp. 137-140
Author(s):  
Anil Kumar Adhikari ◽  
Mahuya Dutta ◽  
Chittra Ranjan Das
Keyword(s):  
Genital Tract ◽  
Surgical Intervention ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Lower Genital Tract ◽  
Clinical Presentations ◽  
Fall From Height

Introduction: The study of lower genital tract trauma has become important in gynaecological practice. There is paucity of reports on this clinical entity from our settings. The main aim of this study is to document injuries in female lower genital tract in Mid-Western Nepal. Methods: Sixty female patients admitted to the hospital with genital tract injuries caused by coitus or accidents were included in the study. Details of the causes of trauma clinical presentations and management were recorded. Results: These injuries were grouped according to etiological factors. This study included 33 (55%) coital injuries and 27 (45%) non- coital injuries. Out of coital injury, 12 cases were criminal assault (rape) in age group of 4 to 18 years. Four unmarried girls had consensual sex. Non-coital injuries were due to fall from height, cattle horn injuries, straddle type of trauma, vulvar haematoma and anorectal injuries. Conclusions: Appropriate surgical intervention can avert morbidity and mortality. Keywords: accident; lower genital tract; Nepal; trauma.

A PROSPECTIVE HISTOPATHOLOGICAL STUDY OF MENINGIOMAS IN A TERTIARY CARE CENTRE OF VIJAYAWADA

2021 ◽  
pp. 11-13
Author(s):  
C.Bhanu Sree ◽  
P. Annapurna ◽  
M. Rajani
Keyword(s):  
Surgical Resection ◽  
Tertiary Care ◽  
Histopathological Study ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Histological Appearance ◽  
Classi Cation ◽  
A Prospective Study

Background: Meningiomas are neoplasms arising from the arachnoidal cap cells in the meningeal coverings of the spinal cord and brain. These are the most common benign intracranial tumours and account for about 13-26% of all primary brain neoplasms. These are generally benign neoplasms of adults most often seen in middle age, but about 10% are atypical or malignant. These neoplasms are graded by WHO as Grade I , II and III . Benign meningiomas can be cured by surgical resection where as higher grade meningiomas require radiotherapy after surgical resection as these higher grade meningiomas have greater recurrence and aggressive behavior. Aims and Objectives: To study the variants and histopathological spectrum of meningioma and prognosis of variants. Material & Methods: The present study is a prospective study conducted in the department of Pathology, Siddhartha medical college from June 2019-May 2020. During this study, 16 cases of meningiomas were diagnosed and reviewed. Result:In our study of 16 cases females were 62.5%. The most common age group is 41-60 yrs (68.75%). Most common variant was noted to be transitional meningioma followed by meningothelial meningioma. Out of the 16 cases, grade I were 81.25%. Conclusion: Meningiomas account for 28-30% of primary central nervous system tumors and unveil a heterogeneous histopathology. The histological appearance of meningioma determines the grading for the management of the various subtypes and also associated with patient's prognosis. Hence a continuous revision of histopathological classication systems is required to improve the diagnostic accuracy. Benign meningiomas are the most common type. From our study, we conclude that transitional meningioma is the most common benign variant.

scholarly journals Profile of new Patients attending Psychiatry Out-patient Department at Lumbini Medical College-Teaching Hospital, Palpa

2018 ◽  
Vol 6 (2) ◽  
pp. 42-44
Author(s):  
B Sharma ◽  
A Devkota ◽  
SC Pant
Keyword(s):  
Psychiatric Illness ◽  
Tertiary Care ◽  
College Teaching ◽  
Age Group ◽  
Household Work ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Level Of Education ◽  
Primary Level ◽  
Medical College

Introduction: Study on prevalence of psychiatric disorders in Palpa and nearby districts which lie in western Nepal, is not much studied till date. We therefore conducted this study aiming to see the pattern of psychiatric illness in an Outpatient Department of Lumbini Medical College which is a tertiary care centre located in Palpa district.Material And Method: : This is a retrospective study where outpatient record of all new cases attending the Psychiatry OPD from 29th Oct 2014 to 29th Dec 2014 were studied and statistical analysis were done. The number of new patients were 107.Results: Out of 107 patients, 60.74 % (65)) were females and 39.26 %( 42) were males. Patients of age group 31-40yrs showed the largest proportion (27.49%) followed by age group 41-50yrs (24.29%). Majority cases were illiterate (69.15%) followed by primary level of education (14.95%). The occupation of most of the cases were household work (35.51%) followed by farming (31.77%). Anxiety disorder (27.10%) was the most frequent diagnosis ahead of “Others” (18.69%) followed by depressive disorder (15.88%).Conclusion: Most of the new patients attending the psychiatry OPD of Lumbini Medical College were females, of 31-40 age group and most of the patients suffered from anxiety disorders. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017, Page: 42-44

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