scholarly journals Comparison of the effects of Duphaston and Cetrotide on oocyte and embryo quality in women undergoing ICSI: A cross-sectional study

2020 ◽  
Author(s):  
Niloofar Motaref ◽  
Sheyda Jouhari ◽  
Afsaneh Mohammadzadeh ◽  
Somaieh Kazemnejad ◽  
Narges Madadi ◽  
...  
Keyword(s):  
Follicle Stimulating Hormone ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lh Surge ◽  
The Third ◽  
Significant Difference ◽  
Premature Lh Surge

Background: Premature luteinizing hormone (LH) surge is one of the causes for assisted reproductive technology cycle cancellation, and it is needed to find novel approaches with improved efficacy and safety profile. Objective: To compare the effects of Duphaston and Cetrotide on the prevention of premature LH surge and characteristics of retrieved follicles and embryos in women undergoing intracytoplasmic sperm injection. Materials and Methods: In this retrospective cross-sectional study, 200 patients who were administrated recombinant follicle-stimulating hormone from the third day of menstruation cycle were included. When the follicular diameter reached above 13-14 mm, Cetrotide was prescribed in the control group, while in the case group, Duphaston was taken orally from the third day of cycle. The retrieved oocytes were fertilized in vitro by intracytoplasmic sperm. The level of hormones on the third day of menstruation and the characteristic of follicles, oocytes, and embryos were compared between the two groups. Results: Duphaston successfully inhibits premature LH surge. There was no significant difference in the level of follicle-stimulating hormone, estradiol, and LH between the case and control groups (p > 0.05). However, results also showed that Duphaston causes more oocyte retrieval in comparison with Cetrotide (p = 0.04). Although, the number of follicles above 14 mm, mature oocyte, and the total number of viable embryos in the case group was slightly higher, it did not reach a significant difference compared with the control group (p > 0.05). Conclusion: Duphaston could be used as an appropriate medication instead of gonadotropin-releasing hormone antagonists in women undergoing controlled ovarian hyperstimulation. Duphaston prescription not only prevents premature LH surge but also improves the number of retrieved oocytes. Key words: Duphaston, Cetrorelix, Dydrogesterone, COH, GnRh antagonis.

scholarly journals Variables associated with family breakdown in healthy and obese/ overweigh adolescents

2014 ◽  
Vol 32 (1) ◽  
pp. 70-77
Author(s):  
Carla Cristina J. N. de Almeida ◽  
Paula de Oliveira Mora ◽  
Valmir Aparecido de Oliveira ◽  
Camila Aparecida Joao ◽  
Carolina Regina Joao ◽  
...  
Keyword(s):  
Public School ◽  
Cross Sectional Study ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obese Adolescents ◽  
Significant Difference ◽  
Family Breakdown

Objective: To evaluate the presence of family breakdown factors among eutrophic and overweight/obese adolescents. Methods: Cross-sectional study of 242 students aged between 14 and 19 years old, from a public school. Each student was weighed, measured and answered a questionnaire with closed questions addressing the presence of family breakdown factors. The adolescents were divided in two groups: euthophic and overweight/obese. The answers of both groups were compared by Fisher's exact and Mann-Whitney tests. Results: There was no statistically significant difference in the prevalence of the studied factors between the two groups. Comparing the number of positive answers (presence of family breakdown factors) and negative ones (absence of family breakdown factors), no difference was observed between the groups. Conclusions: The inclusion of a control group showed that factors of family breakdown, usually identified as associated with obesity in adolescents, may also be present in eutrophic adolescents.

scholarly journals THE IMPACT OF ASTHMAAND ITS MEDICATIONS ON DENTAL CARIES STATUS AND STREPTOCOCCUS MUTANS COUNT IN CHILDREN: A CROSS-SECTIONAL STUDY

2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey
Keyword(s):  
Dental Caries ◽  
Streptococcus Mutans ◽  
Cross Sectional Study ◽  
Control Group ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Significant Difference ◽  
The Impact

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.

scholarly journals Development of cleft children’s permanent canines

2019 ◽  
Vol 67 ◽  
Author(s):  
Manoel Itaguacy Leite NOVAIS JUNIOR ◽  
Manuella Santos Carneiro ALMEIDA ◽  
Camila Helena Machado da COSTA ◽  
Tassia Cristina de Almeida Pinto SARMENTO ◽  
Luis Ferreira de SOUSA FILHO ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tooth Development ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Age Difference ◽  
Cross Sectional ◽  
Panoramic Radiographs ◽  
Significant Difference

ABSTRACT Objective: Evaluating the development of the permanent cuspids in children from Paraíba with cleft lip and palate applying the Nolla and the Demirjian methods. Methods: A cross-sectional study using an inductive approach and applying a comparative statistical procedure and direct documentation research technique. The universe of the study consisted of children assisted at the orthodontic practice of the Brazilian Association of Dentistry - Paraíba Section. The sample comprised 72 pairs of panoramic radiographs of children with and without cleft lip and palate from the same gender and, age difference of up to 30 days, ranging from 5 to 13 years of age. The study has evaluated the development of 576 cuspids. The images were evaluated by three duly calibrated examiners concomitantly, and the calcification stages were determined by a consensus. The stages of the cuspids calcification were evaluated in the panoramic radiographs according to Nolla and Demirjian classifications. Results: The average of the calcification stage of teeth was correspondingly higher in the control group than in the case group, showing a development delay of the cuspid teeth in the cleft lip and palate patients. The lower cuspids were significantly more developed than the upper cuspids (p <0.001). There were no significant differences between the sides. There was early tooth development in females but without significant difference. Conclusion: It was possible to note that patients with cleft lip and palate presented a delay in the development of the permanent cuspids when compared to non-cleft lip and palate patients, thus, reinforcing the importance of the individualization of the orthodontic planning.

scholarly journals Role of Functional Biomarkers to Identify Early Vitamin B12 Deficiency in Patients with Sleeve Gastrectomy: A Cross-Sectional Study

Medicina ◽  
2020 ◽  
Vol 56 (3) ◽  
pp. 142
Author(s):  
Osama Y. Al-Dirbashi ◽  
Charu Sharma ◽  
Nahid Al Dahouri ◽  
Anas Al Aidaros ◽  
Shamma Al-Muhairi ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Vitamin B12 ◽  
Cross Sectional Study ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
B12 Deficiency ◽  
One Year ◽  
Functional Biomarkers

Background and objectives: Although laparoscopic sleeve gastrectomy (LSG) is effective for obesity management, postoperative vitamin B12 (B12) deficiency is of major concern. In this cross-sectional study, we assessed the levels of B12 and its related functional biomarkers, namely, total homocysteine (tHcy), methylmalonic acid (MMA), folate, methylcitric acid (MCA), and hemoglobin (Hb), in one-year postoperative LSG patients and matched controls. Materials and Methods: Plasma B12, tHcy, MMA, folate, and MCA were measured in matched controls (n = 66) and patients (n = 71) using validated liquid chromatography-tandem mass spectrometry techniques and protocols in the United Arab Emirates (UAE). Results: The median B12 concentration in patients (177 pmol/L) was significantly lower (p < 0.001) than in the controls (334.7 pmol/L). The tHcy and MMA levels were significantly increased (p < 0.001 and p = 0.011, respectively) and folate levels were significantly decreased (p = 0.001) in the LSG patients compared to the controls. Interestingly, no significant difference in MCA levels were observed between the two groups. The levels of tHcy and MMA were concomitantly increased with the decreased folate levels in postoperative LSG patients when compared with the controls. The Hb levels were significantly lower in males and females in the patient group compared with those in the control group, respectively (p = 0.005 and p = 0.043). Conclusions: This is the first report of serum levels of B12 and its functional biomarkers in postoperative LSG patients among a local population from the UAE. Our findings revealed significant alterations of the B12 biomarkers, total B12, MMA, and tHcy in one-year postoperative LSG patients.

Radiotherapy- or Radical Surgery–Induced Female Sexual Morbidity in Stages IB and II Cervical Cancer

2014 ◽  
Vol 24 (4) ◽  
pp. 800-805 ◽  
Author(s):  
Yuko Harding ◽  
Takuma Ooyama ◽  
Tomoko Nakamoto ◽  
Akihiko Wakayama ◽  
Wataru Kudaka ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Sexual Function ◽  
Cancer Survivors ◽  
Radical Surgery ◽  
Cross Sectional Study ◽  
Control Group ◽  
Female Sexual Function ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

ObjectiveThe objective of this study was to evaluate the sexual function in cervical cancer survivors after radiotherapy (RT) or radical surgery (RS).MethodsThis was an observational and cross-sectional study. The Female Sexual Function Index (FSFI) self-reported questionnaires were distributed to 175 patients after RT (RT group) or RS (RS group) and 521 healthy women (control) between 2011 and 2012. Sexual functions were compared among these 3 groups.ResultsEligible 92 patients (46 in RT group, 46 in RS group) and 148 control subjects were included for analysis. There was a significant difference in median (range) FSFI total score of 5.5 (3.6–34.7) in the RT group, 18.9 (3.4–31.2) in the RS group, and 22.1 (2–34.2) in the control group (P < 0.001). The median FSFI total score in the RT group was significantly lower than that in the control group (P < 0.001). Six sexual domains (desire, arousal, lubrication, orgasm, satisfaction, pain) were all significantly affected in the RT group, and no significant differences, except pain, were observed in the RS group as compared with the control group.ConclusionsInterventions involving counseling and rehabilitation for female sexual function should be provided in cervical cancer survivors, especially after RT.

scholarly journals Neurophobia: How Do Sudanese Medical Students Perceive Neurology- A Cross-sectional Study.

2021 ◽  
Author(s):  
Hiba A. A. Ali ◽  
Mohamed Alebeed ◽  
Yousuf Hasan Yousuf Bakhit
Keyword(s):  
Job Satisfaction ◽  
Medical Students ◽  
Medical Schools ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Large Contribution ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Third ◽  
Significant Difference

Abstract Background: The fear of neuroscience by medical students is a global issue known as neurophobia which has been detected in medical schools from both developing and developed countries. It may contribute to the decreased number of neurologists that is already found to be low globally and augment the growing burden of neurological disorders. This study aimed to evaluate this issue among Sudanese medical students.Methods: A cross-sectional study was conducted on medical students from 8 medical schools using an online form questionnaire and responses were collected. Results: A total of 338 responses with 90.4% response rate were collected. Neurology was reported as the most difficult subject to learn (mean ± SD = 3.88 ± 0.90)(P< .01),the second least subject in drawing up differential diagnosis(3.32 ± 1.07) )(P =.000), the third least regarding confidence in clinical examination (3.23 ± 1.24)(P =.000),the third poorest quality of teaching (3.12 ± 1.26)(P =.000), and the third favorite subject as a career option (3.41 ± 1.4)(P > .004).Neuroanatomy was the biggest contributor to the difficulty of neurology (have a very large or large contribution by 51.5% of students) and More/Improved peer discussions were the most factor that could improve neurology teaching (mean ± SD = 3.47 ± 1.39). students perceive a career in neurology to be associated with good travel and research opportunities and poor job satisfaction and work/life balance. ability to make a significant difference in a patient’s life was the most factor encouraging students to chase a career in neurology (21.6%of students) and job satisfaction was the most discouraging factor (20.7%). On performing logistic regression, caring for a friend or relative suffering from neurological disease and increased confidence in knowing exactly what neurologists do were found to have a significant effect on increasing the possibility of pursuing a career in neurology (P =.01 and P< .005 respectively).Conclusion: Students’ perception of neurology is almost the same worldwide and didn’t change over decades in contrast to the growing burden of neurological diseases and population aging. So, a lot of work should be done globally to investigate and manage this issue.

scholarly journals Three-dimensional volumetric evaluation of the different mandibular segments using CBCT in patients affected by juvenile idiopathic arthritis: a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Davide Cavagnetto ◽  
Andrea Abate ◽  
Alberto Caprioglio ◽  
Paolo Cressoni ◽  
Cinzia Maspero
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Three Dimensional ◽  
Pairwise Comparison ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Unaffected Side ◽  
Cross Sectional ◽  
Affected Side ◽  
Significant Difference

Abstract Background There is currently no information on how different mandibular segments are affected by juvenile idiopathic arthritis. The aim of this paper is to assess volumetric differences of different mandibular segments in subjects with unilateral and bilateral JIA and to compare them with non-JIA control volumes. Materials and methods Forty subjects with unilateral TMJ involvement and 48 with bilateral TMJ involvement were selected for the case group and 45 subjects with no known rheumatic comorbidities for the control group. The mandible of each subject was divided according to a validated method into different paired volumes (hemimandible, condyle, ramus and hemibody). Results The ANOVA test revealed a statistically significant difference in all the groups for condylar and ramus volumes, and the pairwise comparison evidenced a statistically significant higher condylar and ramus volume in the control group (1444.47 mm3; 5715.44 mm3) than in the affected side in the unilateral JIA group (929.46 mm3; 4776.31 mm3) and the bilateral JIA group (1068.54 mm3; 5715.44 mm3). Moreover, there was also a higher condylar volume in the unaffected side in the unilateral JIA group (1419.39 mm3; 5566.24 mm3) than in the bilateral JIA group and the affected side in the unilateral JIA group. Conclusions The affected side of unilateral JIA patients showed statistically significant lower volumes in the hemimandible, in the condyle and in the ramus. The largest total mandibular volume was observed in the control group, followed by the unilateral JIA group and, lastly, by the bilateral JIA group.

Types of yeasts that cause vulvovaginal candidiasis in chronic users of corticosteroids

2018 ◽  
Vol 57 (6) ◽  
pp. 681-687 ◽  
Author(s):  
Mohammed A Farhan ◽  
Ahmed M Moharram ◽  
Tareq Salah ◽  
Omar M Shaaban
Keyword(s):  
Antifungal Agents ◽  
Cross Sectional Study ◽  
Vulvovaginal Candidiasis ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Glucose Agar ◽  
Chronic Corticosteroid ◽  
Health Hospital

AbstractThe current study aims to compare between the types of yeasts that cause vulvovaginal candidiasis (VVC) in women using corticosteroid medication compared to nonusers and estimate their sensitivity to available commercial antifungal agents. In a descriptive analytical cross-sectional study, we recruited 41 chronic corticosteroid users diagnosed clinically to have VVC from Women's Health Hospital, Assiut University, Egypt. Forty-seven age-matched women with VVC were recruited as a control group. Full history and clinical examination were performed. Vaginal sterile swab obtained from the vagina of each participant was subjected to direct Gram-stained smear examination as well as a culture on Sabouraud's glucose agar and HiCrome Candida agar. Further identification of the isolates was done using traditional methods. Fifty out of 88 samples (56.8%) were positive in culture including 25 samples (61%) from corticosteroid users group and 25 (53.2%) from noncorticosteroid users with no statistically significant difference (P = .302). The chronic corticosteroid users had more incidence of recurrent VVC as compared to nonusers (65.9% vs 40.4%, respectively) (P = .015). There was a significantly higher rate of non-Candida albicans (NCA) infections in corticosteroid users compared with nonusers (48% vs 20%, respectively) (P = .036). A higher significant difference in resistance of the isolates against clotrimazole (P = .003) and ketoconazole (P = .017) was demonstrated in corticosteroid users compared to nonusers. Thus, chronic corticosteroid use causes frequent attacks of VVC and increases the frequency of infection by NCA strains. Also, it increases resistance to common antifungal agents especially azole group.

Correlation between gastrointestinal symptoms and adherence to traditional Persian medicine dietary recommendations in patients with vitiligo; a cross-sectional study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Amir Mohammad Jaladat ◽  
Ehsan Amiri-Ardekani ◽  
Pariya Sadat Ramezani ◽  
Mohadese Boroughani ◽  
Morteza Emami Alorizi ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Sectional Study ◽  
Dietary Recommendations ◽  
Cross Sectional ◽  
Persian Medicine ◽  
Traditional Persian Medicine

Abstract Objectives Vitiligo is a chronic disease associated with the depigmentation of regions of the skin secondary to structural or functional damage to melanocytes. This damage results from interactions between the immune system and oxidative stress. In traditional Persian medicine (TPM), the concept of ‘Barass’ or ‘Pissi’ encompasses a group of skin diseases including vitiligo, for which there has been an emphasis on the preventive and therapeutic role of dietary modifications. Methods In this cross-sectional study, 200 vitiligo patients and 200 controls were enrolled with a random sampling method. The participants included patients with vitiligo referred to the Dermatology Clinic of Shahid Faghihi Hospital (Shiraz, Iran), with the control group being comprised individuals who referred to this clinic for cosmetic purposes. Questionnaires comparing the severity of gastrointestinal symptoms and the rate of adherence to TPM dietary recommendations were filled by all participants. Data were analyzed using SPSS version 24.0. Results The case group was significantly less adherent to TPM recommendations than the control group (8.25 ± 27.16 vs. 31.8 ± 10.47; p<0.001). However, there was no significant difference between both groups in the Gastrointestinal Symptom Rating Scale (GSRS) scores (14.09 ± 14.84 vs. 12.62 ± 11.71; p = 0.105). In the case group, the level of adherence to the recommendations of TPM was significantly lower among patients with lower education levels (R=−0.194; p=0.017). Furthermore, there was a significant negative relationship between the length of the disease and adherence to TPM dietary recommendations (R=−0.247; p=0.002). Conclusions In this study, the level of adherence to TPM recommendations was significantly lower among patients with vitiligo than the control group. Hence, further studies are suggested to identify the probable role of dietary habits in the pathogenesis of vitiligo.

The expression of BECN1, LC3B, and BCL2 genes in eutopic endometrium of patients with adenomyosis: A cross-sectional study

2021 ◽  
pp. 228402652110467
Author(s):  
Siriluk Tantanavipas ◽  
Tepchongchit Aojanepong ◽  
Wanwisa Waiyaput ◽  
Areepan Sophonsritsuk
Keyword(s):  
Mrna Expression ◽  
Geometric Mean ◽  
Premenopausal Women ◽  
Cross Sectional Study ◽  
Control Group ◽  
Sectional Study ◽  
Menstrual Phase ◽  
Cross Sectional ◽  
Eutopic Endometrium ◽  
Significant Difference

Introduction: Both autophagy and apoptosis play a role in the cyclic remodeling of the endometrium. The abnormal regulation of genes and signaling pathways in the eutopic endometrium plays a role in the abnormal migration and implantation in adenomyosis. Objective: The present study investigates the mRNA expression of autophagy and apoptosis-related genes BECN1, LC3B, and BCL2 in the eutopic endometrium of patients with adenomyosis compared with healthy premenopausal women. Materials and methods: The present work was a cross-sectional study conducted between July 2018 and April 2019. The participants were 32 premenopausal women who attended the surgery for adenomyosis and other benign gynecological conditions. The participants were divided into two groups, with 16 women in the adenomyosis group and 16 healthy women in the control group. Endometrial tissues were collected during the proliferative menstrual phase for a quantitative real-time polymerase chain reaction. Results: The mRNA expression of BECN1, LC3B, and BCL2 were normalized by geometric mean mRNA expression of actin and GAPDH. There was no significant difference in mRNA expression for all three genes when comparing the control and adenomyosis groups. Conclusions: The mRNA expressions of autophagy-related genes BECN1 and LC3B and anti-apoptosis-related gene BCL2 were not significantly different in the eutopic endometrium of patients with adenomyosis compared with healthy premenopausal women during the proliferative menstrual phase.

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