scholarly journals Medicinal Plants With Antileishmanial Properties: A Review Study

2020 ◽  
Author(s):  
Elham Gharirvand Eskandari ◽  
Mahbubeh Setorki ◽  
Monir Doudi
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Cutaneous Leishmaniasis ◽  
Medicinal Herbs ◽  
Effective Vaccine ◽  
Indigenous Plants ◽  
Synthetic Drugs ◽  
The Past ◽  
Review Study ◽  
Leishmania Parasites

Background: Leishmaniasis is an infectious disease caused by various species of the Leishmania parasites. An effective vaccine or drug to prevent the infestation or a suitable medication to cure the disease without side effects has not been provided yet. Objectives: The use of medicinal herbs in the treatment of many diseases, especially parasitic ones, dates back to prehistoric times. This article is a review study on these herbs used for the treatment of leishmaniasis. Methods: In this regard, we searched PubMed, Science Direct, and Google Scholar databases. We prepared this review on the treatment of cutaneous leishmaniasis with medicinal plants because of the prevalence of this disease, chemical drugs’ failure to fully control it, increase in the number of reports on drug resistance, and contradictory research on the side effects of synthetic drugs. Results: In general, the use of medicinal herbs for the treatment of various diseases has a long history. Because of Iran’s diverse climate and flora, we have the potential to identify the active herbal ingredients in different indigenous plants of the country and extract them to produce them on an industrial scale. Conclusion: In this article, several herbs used to treat cutaneous leishmaniasis from the past to today in Iran and other countries are studied and evaluated.

scholarly journals Use of drugs of medicinal herbs for insomnia treatment

2019 ◽  
Vol 2 (19) ◽  
pp. 11-18
Author(s):  
E. A. Korabelnikova ◽  
Al. B. Danilov
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Raw Materials ◽  
Modern Medicine ◽  
Medicinal Herbs ◽  
Individual Sensitivity ◽  
Synthetic Drugs ◽  
Rapid Effect ◽  
Insomnia Treatment ◽  
Vegetable Raw Materials

Therapy with medicinal herbs in the complex of therapeutic actions for insomnia occupies a special place. The main advantage of phytotherapy of sleep disorders is their high therapeutic efficacy in the absence of side effects, except in cases of individual sensitivity to individual components of the drug. Unlike synthetic drugs, drugs, which are based on vegetable raw materials, have a rapid effect on the extracellular and intracellular metabolic processes. Therefore, the therapeutic effect of medicinal plants is persistent and prolonged. The method of phytotherapy is an alternative and highly effective method of treatment of insomnia, and it should not reject, but significantly complement other methods of modern medicine.

scholarly journals Medicinal herbs with anti-depressant effects

2020 ◽  
Vol 9 (4) ◽  
pp. 309-317 ◽  
Author(s):  
Mahbubeh Setorki
Keyword(s):  
Clinical Trials ◽  
Side Effects ◽  
Complete Recovery ◽  
Medicinal Herbs ◽  
Double Blind ◽  
Synthetic Drugs ◽  
Positive Effects ◽  
Antidepressant Effects ◽  
Life Threatening ◽  
Echium Amoenum

Depression is a life-threatening chronic illness which affects people worldwide. Drugs used to treat this disease have multiple side effects and may cause drug-drug or drug-food interactions. Additionally, only 30% of patients respond adequately to the existing drugs and the remaining do not achieve complete recovery. Thus, finding effective treatments that have adequate efficacy, fewer side effects and lower cost seem to be necessary. The purpose of this study was to review animal and double-blind clinical studies on the anti-depressant effects of medicinal herbs. In this study, validated scientific articles indexed in PubMed, SID, Web of Science and Scopus databases were reviewed. A database search was performed using the following terms: clinical trials, depression, major depressive disorder, essential oil, extract and medicinal plant. Positive effects of a number of herbs and their active compounds such as St John’s-wort, saffron, turmeric, ginkgo, chamomile, valerian, Lavender, Echium amoenum and Rhodiola rosea L. in improvement of symptoms of mild, moderate or major depression have been shown in clinical trials. The above plants show antidepressant effects and have fewer side effects than synthetic drugs. Hence, they have the potential to treat patients with depression.

scholarly journals A review on importance of bioactive compounds of medicinal plants in treating idiopathic pulmonary fibrosis (special emphasis on isoquinoline alkaloids)

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sai Sushma Dudala ◽  
T. C. Venkateswarulu ◽  
Sushma Chandulee Kancharla ◽  
Vidya Prabhakar Kodali ◽  
D. John Babu
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Bioactive Compounds ◽  
Normal Lung ◽  
Isoquinoline Alkaloids ◽  
Biochemical Tests ◽  
Synthetic Drugs ◽  
Promising Therapeutic Approach

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown cause which disrupts the normal lung architecture and functions by deregulating immune responses and ultimately leads to the death of the individual. A number of factors can lead to its development and currently there is no cure for this disease. Main text There are synthetic drugs available to relieve the symptoms and decelerate its development by targeting pathways involved in the development of IPF, but there had also been various side effects detected by their usage. It is known since decades that medicinal plants and their compounds have been used all over the world in natural medicines to cure various diseases. This review article is focused on the effects of various natural bioactive compounds of 26 plant extracts that show prophylactic and therapeutic properties against the disease and so can be used in treating IPF replacing synthetic drugs and reducing the side effects. Short conclusion This review includes different mechanisms that cause pulmonary fibrosis along with compounds that can induce fibrosis, drugs used for the treatment of pulmonary fibrosis, diagnosis, the biochemical tests used for the experimental study to determine the pathogenesis of disease with a special note on Isoquinoline alkaloids and their role in reducing various factors leading to IPF thus providing promising therapeutic approach.

scholarly journals Heartburn and effective herbal remedies: A systematic review study in Iranian ethnobotanical documents

2021 ◽  
Vol 10 (2) ◽  
pp. 149-155
Author(s):  
Gholam Basati ◽  
Pardis Ghanadi ◽  
Pegah Shakib ◽  
Majid Hamidi ◽  
Peyman Amanolahi Baharvand
Keyword(s):  
Medicinal Plants ◽  
Nigella Sativa ◽  
Punica Granatum ◽  
Gastrointestinal Diseases ◽  
Herbal Remedies ◽  
Medical Sciences ◽  
Anethum Graveolens ◽  
Mentha Pulegium ◽  
Synthetic Drugs ◽  
Review Study

Every year, millions of people worldwide get sick with gastrointestinal diseases such as heartburn. Certain herbs contribute to the alleviation of heartburn, nausea, and improvement of digestion. Moreover, these herbs do not have as many side effects as synthetic drugs. As a health problem and one of the challenging issues in medical sciences, heartburn is common in children and adults worldwide. Hence, in the present study, we tried to report medicinal plants used in cultures and traditions of different regions of Iran to treat heartburn in children and adults. In this review study, articles of Iranian ethnobotanical sources were searched with the keywords of ethnobotanics, heartburn, children, adult, medicinal plants, and Iran. Journal articles published from 2010 to 2019 in several Iranian and International databases, including ISI Web of Science, PubMed, Scopus, ISC, Magiran, were searched to find relevant articles and information. Anethum graveolens L., Punica granatum L., Mentha pulegium, Thymus kotschyanus Boiss. & Hohen., Achillea millefolium, Ocimum basilicum, Nigella sativa, etc., are the plants used in different parts of Iran to treat heartburn.

Colic Phytotherapy in Iranian Ethnobotany: An Overview of the ffectiveness of the Most Important Native Medicinal Plants of Iran on olic Disease

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Mehrdad Karimi ◽  
Mahnaz Mardani ◽  
Leila Mahmoodnia
Keyword(s):  
Medicinal Plants ◽  
Health Effects ◽  
Medicinal Herbs ◽  
Tanacetum Parthenium ◽  
Gastrointestinal Problems ◽  
Wide Range ◽  
Review Study ◽  
Sisymbrium Irio

Colon disorders and diseases are of the significant gastrointestinal problems. Medicinal plants have a wide range of health effects. Medicinal herbs are used in the treatment of various diseases. Many native medicinal plants of Iran have anti-colic effects. Thus, in this review, the medicinal plants of Iranian ethnobotanical resources with anti-colic effects were reported. In this review study, a search for articles by the keywords colic, ethnobotanical, and medicinal plants was done. A search on the databases, such as Scopus, ISI, SID, MegaIran, and a number of other databases was performed. Based on the review results of ethnobotanical sources, it was revealed that the medicinal herbs of chamomile, lote, yarrow, dill, Tanacetum parthenium, Sisymbrium irio, plantain, Damascus rose, licorice, garden sage, oregano, etc. are of the most important anticolic medicinal plants.

scholarly journals A Review Study on the Effect of Iranian Herbal Medicines on Opioid Withdrawal Syndrome

2015 ◽  
Vol 20 (4) ◽  
pp. 302-309 ◽  
Author(s):  
Marzieh Ebrahimie ◽  
Mahmoud Bahmani ◽  
Hedayatollah Shirzad ◽  
Mahmoud Rafieian-Kopaei ◽  
Kourosh Saki
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Withdrawal Syndrome ◽  
Experimental Studies ◽  
Herbal Medicines ◽  
Morphine Withdrawal ◽  
Mentha Piperita ◽  
Synthetic Drugs ◽  
Important Challenge ◽  
Opioid Withdrawal Syndrome

Addiction is a chronic and recurring disease that recurrence phenomenon is the most important challenge in treatment of this disease. Recent experiences have shown that synthetic drugs have undesirable side effects. Recent studies on medicinal plants have shown that they might be effective in treatment of different stages of addiction with lower side effects and costs. The aim of this study was to review the effects of medicinal plants in the treatment of morphine addiction in experimental animals. In this review article, by using keywords of morphine, withdrawal, and plants or herbal medicine in databases of indexing cites, desired articles were obtained since 1994. Inclusion criteria for selecting articles were the articles related to application of medicinal plants in decreasing symptoms resulting from morphine withdrawal were selected. Results of this study on experimental studies have shown that medicinal plants such as Trachyspermum copticum L and Melissa officinalis decrease the symptoms of withdrawal syndrome in a dose-dependent. Also, medicinal plants like Avena sativa, Hypericum perforatu, Passiflora incarnate, Valeriana officinalis, Satureja hortensis L, and Mentha piperita can have effects on behavior, emotions, and other problems of addicts, decreasing withdrawal symptoms. Results of this study showed that medicinal plants can be effective in controlling deprivation, decreasing dependency creation, and possibly detoxification of opioid addicts.

scholarly journals Olax scandens: The Plant of The Researchers- A Review

2021 ◽  
Vol 12 (1) ◽  
pp. 504-507
Author(s):  
Johnsy Mary F ◽  
Komala M
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Adverse Effects ◽  
Western Ghats ◽  
Science And Technology ◽  
Human Beings ◽  
Synthetic Drugs ◽  
Anti Inflammatory ◽  
The Western Ghats ◽  
Pharmacological Profiles

Plants had been a source of food for human beings from the start of the evolution of mankind. Besides food, herbs served us as the source of medicines to treat ailments. Plants had been investigated for the chemical moieties that are potent in treating many diseases. With the development of science and technology, there had been various drugs, synthesized to treat diseases. But the chemicals that were synthesized had serious adverse effects and side effects. So there has been a focus on herbs and medicinal plants in search of the alternatives for synthetic drugs. In this paper, Olax scandens  had been reviewed for its Pharmacognostic, Phytochemical and Pharmacological profiles which revealed the presence of various phytoconstituents like glycosides, tannins, phenols, flavonoids, alkaloids etc. Few areas include the Himalayas and sub-Himalayan regions like northern parts of Bihar, Kumaon. The plant also grows widely in Deccan forest and the Western Ghats. The plant is native to countries like India, Srilanka, Bangladesh, Malaysia, Burma, Thailand, Vietnam and Java. Olax is s scandent shrub which grows to 5m height. The leaf is simple, alternate and oblong with the lanceolate surface. The inflorescence is axillary, racemose and panicle. The flowers are white, and the fruits are drupes and ovoid in shape. The plant was proven to exhibit anti-bacterial, laxative, anti-inflammatory, anti-diabetic, antipyretic activities.

scholarly journals Anti-Schistosomal Activity of Medicinal Plants: Mini Review

2021 ◽  
Vol 10 (3) ◽  
pp. 2352-2360
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Schistosoma Mansoni ◽  
Schistosoma Haematobium ◽  
Parasitic Disease ◽  
Research Teams ◽  
Synthetic Drugs ◽  
Major Species ◽  
Disease Spreading

Schistosomiasis is a parasitic disease caused by the Schistosoma genus' parasites, and several complications associated with this pathology can lead to death. Indeed, Schistosoma mansoni and Schistosoma haematobium are the major species responsible for this disease, spreading particularly in Africa. While synthetic drugs used to treat Schistosomiasis are often not effective and represent major side effects. In this context, many research teams are currently focusing on identifying natural secondary metabolites with anti-schistosomal properties. Therefore, this work highlighted an overview of some medicinal plants' anti-schistosomal activity and their bioactive compounds.

Iran's Most Important Indigenous Medicinal Plants with Diuretic Properties: An Overview of Iranian Ethnobotanical Resources

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Mehrdad Karimi ◽  
Leila Mahmoodnia ◽  
Sadegh Rezapour
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Urinary Retention ◽  
Complementary Therapies ◽  
The Elderly ◽  
Medicinal Herbs ◽  
Present Review ◽  
Residual Urine ◽  
Review Study ◽  
Different Parts

By definition, urinary retention is called the inability to completely empty urine so that the volume of residual urine after discharge is higher than 100 cc and lower than 200 cc in the elderly. For the treatment of urinary retention, there are different therapeutic methods, such as traditional medicine and complementary therapies. One of the methods of traditional medicine is using medicinal plants. Medicinal herbs are effective on the treatment of many diseases due to their active and antioxidant ingredients. Many native medicinal plants of Iran are effective on the treatment of urinary retention and have diuretic properties. Thus, in this review, the effective medicinal plants of Iranian ethnobotanical resources on hemorrhoid were reported. In the present review study, a search for articles by the keywords hemorrhoid, ethnobotanical, and medicinal plants was done. A search on the databases, such as Scopus, ISI C, S ID, Mega Iran, and a number of other databases was performed. Search the databases, such as databases including Scopus, ISI C, S ID, and a number of other sites were Mgayran. Based on the results obtained, 45 herbs from different parts of Iran are traditionally used to treat urinary retention. Such medicinal plants as chicory, nettles, sorrel, milk, cheese, oleander, wild pistachio, fumitory, jujube, basil, nigella seeds, licorice, etc. are of the effective herbs.

scholarly journals Anticancer activity of Nigerian medicinal plants: a review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Franklyn O. Ohiagu ◽  
Paul C. Chikezie ◽  
Chinwendu M. Chikezie ◽  
Christian E. Enyoh
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Anticancer Activity ◽  
Cancer Cell ◽  
Bioactive Compounds ◽  
Main Body ◽  
Anticancer Activities ◽  
Plant Parts ◽  
Synthetic Drugs ◽  
Inhibition Of Angiogenesis

Abstract Background Cancer is currently the leading cause of death globally and the number of deaths from cancer is on the rise daily. Medicinal plants have been in continuous use over the years for the management of cancer, particularly, in most developing countries of the world including Nigeria. The use of synthetic drugs for the treatment of cancer is often accompanied by toxic side effects. Thus, the alternative use of readily available and inexpensive medicinal plants is the panacea to the toxic side effects associated with synthetic drugs. Main body The present review summarized the anticancer activity of 51 medicinal plants that are widespread in all regions of Nigeria. Furthermore, the proposed anticancer pharmacological actions as well as the anticancer bioactive compounds, the type of cancer cell inhibited, the plant parts responsible for the anticancer activity, and the nature of the extracts used for the studies were discussed in this review. The 51 Nigerian medicinal plants were reported to exhibit anticancer activities of the prostate, cervices, lung, skin, colon, esophagus, blood, ovary, central nervous system/brain, breast, stomach, pancreas, larynx, and kidney. The major classes of bioactive compounds indicated to be responsible for the anticancer activity include the polyphenols, flavonoids, alkaloids, saponins, triterpenes, tannins, and quinones. The major anticancer pharmacological actions of these bioactive compounds were antiproliferative, cytotoxic, cytostatic, antimetastatic, apoptotic, and antioxidative as well as provoked cell cycle arrest, inhibition of angiogenesis and reduction of cancer cell viability. Conclusion The Nigerian medicinal plants can be harnessed to provide for readily available and inexpensive anticancer drugs in the future because the plants reported in this review showed promising anticancer activity.

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