scholarly journals Heartburn and effective herbal remedies: A systematic review study in Iranian ethnobotanical documents

2021 ◽  
Vol 10 (2) ◽  
pp. 149-155
Author(s):  
Gholam Basati ◽  
Pardis Ghanadi ◽  
Pegah Shakib ◽  
Majid Hamidi ◽  
Peyman Amanolahi Baharvand
Keyword(s):  
Medicinal Plants ◽  
Nigella Sativa ◽  
Punica Granatum ◽  
Gastrointestinal Diseases ◽  
Herbal Remedies ◽  
Medical Sciences ◽  
Anethum Graveolens ◽  
Mentha Pulegium ◽  
Synthetic Drugs ◽  
Review Study

Every year, millions of people worldwide get sick with gastrointestinal diseases such as heartburn. Certain herbs contribute to the alleviation of heartburn, nausea, and improvement of digestion. Moreover, these herbs do not have as many side effects as synthetic drugs. As a health problem and one of the challenging issues in medical sciences, heartburn is common in children and adults worldwide. Hence, in the present study, we tried to report medicinal plants used in cultures and traditions of different regions of Iran to treat heartburn in children and adults. In this review study, articles of Iranian ethnobotanical sources were searched with the keywords of ethnobotanics, heartburn, children, adult, medicinal plants, and Iran. Journal articles published from 2010 to 2019 in several Iranian and International databases, including ISI Web of Science, PubMed, Scopus, ISC, Magiran, were searched to find relevant articles and information. Anethum graveolens L., Punica granatum L., Mentha pulegium, Thymus kotschyanus Boiss. & Hohen., Achillea millefolium, Ocimum basilicum, Nigella sativa, etc., are the plants used in different parts of Iran to treat heartburn.

scholarly journals Antispasmodic Potential of Medicinal Plants: A Comprehensive Review

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Abdur Rauf ◽  
Muhammad Akram ◽  
Prabhakar Semwal ◽  
Adil A. H. Mujawah ◽  
Naveed Muhammad ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Relevant Literature ◽  
Smooth Muscles ◽  
Gastrointestinal Diseases ◽  
Biologically Active ◽  
Anethum Graveolens ◽  
Mentha Pulegium ◽  
Foeniculum Vulgare ◽  
Medical Needs ◽  
Therapeutic Benefits

Numerous medicinal plants have been utilized for the treatment of different types of diseases and disorders including gastrointestinal (GI) diseases. GI diseases are the most common complaints that normally affects the largest proportion of children and adolescents with overlapping clinical manifestation in diagnosis and medical needs. Drugs with antispasmodic effects are normally applied for the symptomatic treatment of contraction and cramping of smooth muscles in gastrointestinal diseases as well as in other critical clinical situations. In alternative system of medicines, the antispasmodic herbs played a significant role in the cure of GI diseases. These medicinal plants and their herbal products are used from generation to generation because of multiple nutritional and therapeutic benefits. The multiple uses might be attributed to the presence on biologically active chemical constitutes. The main aim of this review is to focus on the medicinal potential of plants possessing antispasmodic activities with their proposed mechanism of action. Several databases such as Google Scholar, Cochrane database, Scopus, and PubMed were used to search the relevant literature regarding “plants with antispasmodic activities.” This present study highlights the updated and quantified information on several medicinal plants with antispasmodic activity like Zanthoxylum armatum, Matricaria chamomilla, Foeniculum vulgare, Pycnocycla spinosa, Atropa belladonna, Lavandula angustifolia, Mentha pulegium, Glycyrrhiza ularensis, Anethum graveolens, and Origanum majorana. Moreover, recent studies on other medicinal plant species also have been included in this review article. Additionally, the study also revealed that the active compounds of all these plants possess significant spasmolytic effect which is safest, efficacious, and cost effective as compared to the available synthetic drugs.

scholarly journals Medicinal Plants With Antileishmanial Properties: A Review Study

2020 ◽  
Author(s):  
Elham Gharirvand Eskandari ◽  
Mahbubeh Setorki ◽  
Monir Doudi
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Cutaneous Leishmaniasis ◽  
Medicinal Herbs ◽  
Effective Vaccine ◽  
Indigenous Plants ◽  
Synthetic Drugs ◽  
The Past ◽  
Review Study ◽  
Leishmania Parasites

Background: Leishmaniasis is an infectious disease caused by various species of the Leishmania parasites. An effective vaccine or drug to prevent the infestation or a suitable medication to cure the disease without side effects has not been provided yet. Objectives: The use of medicinal herbs in the treatment of many diseases, especially parasitic ones, dates back to prehistoric times. This article is a review study on these herbs used for the treatment of leishmaniasis. Methods: In this regard, we searched PubMed, Science Direct, and Google Scholar databases. We prepared this review on the treatment of cutaneous leishmaniasis with medicinal plants because of the prevalence of this disease, chemical drugs’ failure to fully control it, increase in the number of reports on drug resistance, and contradictory research on the side effects of synthetic drugs. Results: In general, the use of medicinal herbs for the treatment of various diseases has a long history. Because of Iran’s diverse climate and flora, we have the potential to identify the active herbal ingredients in different indigenous plants of the country and extract them to produce them on an industrial scale. Conclusion: In this article, several herbs used to treat cutaneous leishmaniasis from the past to today in Iran and other countries are studied and evaluated.

scholarly journals An Overview on Ethnopharmacology of Different Medicinal Plants of Odisha State of India in the Management of Diabetes Mellitus

2021 ◽  
Vol 33 (11) ◽  
pp. 2589-2598
Author(s):  
Deepankar Rath ◽  
Gurudutta Pattnaik ◽  
Biswakanth Kar
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Ricinus Communis ◽  
Cocos Nucifera ◽  
Aloe Vera ◽  
Traditional Healers ◽  
World Health ◽  
Herbal Remedies ◽  
Synthetic Drugs ◽  
Health Organization

Diabetes mellitus, commonly known as diabetes, is a group of metabolic disorder associated with elevated blood glucose level. World health organization recommended the traditional and herbal remedies for the diabetic management. The application of herbal remedies is extremely increased worldwide in the last three decades. Most of the synthetic drugs were discovered from the plant source out of different regions of the world to meet the demand. Several medicinal plants like Gymnema sylvestre, Pterocarpus marsupium, Catharanthus roseus, Trigonella foenum, Annona squamosa, Aegle marmelos, Withania somnifera, Boerhavia diffusa, Boerhavia erecta, Momordica charantia, Cocos nucifera, Ricinus communis, Azadira chtaindica and Aloe vera have been reported to have varying level of hypoglycemic property. One of the factors involved in the evolution of diabetic convolutions is the impairment due to free radicals and hence a compound with antioxidant and antidiabetic potential would be more effective. The present review article was designed to provide an absolute data on these medicinal plant based remedies by using the traditional healers of Odisha state, India.

scholarly journals An Evidence-Based Study on Medicinal Plants for Hemorrhoids in Medieval Persia

2017 ◽  
Vol 22 (4) ◽  
pp. 969-981 ◽  
Author(s):  
Mohammad Hashem Hashempur ◽  
Fatemeh Khademi ◽  
Maryam Rahmanifard ◽  
Mohammad M. Zarshenas
Keyword(s):  
Medicinal Plants ◽  
Conventional Medicine ◽  
Gastrointestinal Diseases ◽  
Scientific Data ◽  
Herbal Remedies ◽  
Evidence Based ◽  
Traditional Medicines ◽  
Analgesic Effects ◽  
Persian Medicine ◽  
Traditional Persian Medicine

Hemorrhoids is one of the most common gastrointestinal diseases. There are several therapeutic options associated with some complications. Therefore, researchers look for traditional medicines as a potential resource for introduction of new natural drugs. The current study reports an evidence-based review of herbal remedies for hemorrhoids in traditional Persian medicine. A comprehensive survey about hemorrhoids on the most important manuscripts of traditional Persian medicine was done. Then, scientific data banks were searched for possible related properties of each herb in the conventional medicine. We reported some historical aspects of traditional Persian medicine view on classification, examination, and predisposing factors of hemorrhoids. In addition, we have reported 105 medicinal plants belonging to 51 families. More than half of the reported herbs exhibited anti-inflammatory and analgesic effects. Although lack of human studies regarding the mentioned herbs is noted, positive results from experimental findings can be considered for new drug discovery supported by traditional and medieval experiences.

Mechanistic Aspects of Medicinal Plants and Secondary Metabolites against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

2021 ◽  
Vol 27 ◽  
Author(s):  
Khojasteh Malekmohammad ◽  
Mahmoud Rafieian-Kopaei
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Severe Acute Respiratory Syndrome ◽  
Conformational Changes ◽  
Nigella Sativa ◽  
Spike Protein ◽  
Herbal Remedies ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Related Factor

Background and Objective: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a highly pathogenic virus, is responsible for a respiratory disease termed coronavirus disease 2019 (COVID-19). SARS-CoV-2 genome encodes various structural and non-structural proteins, which are necessary for viral entry and replication. Among these proteins, papain-like protease (PLpro), 3C-like protease (3CLpro), RNA-dependent RNA polymerase (RdRp), helicase, a serine protease, and spike protein are potential targets of herbal remedies and phytocompounds for inhibition of viral infection and replication. There is at present no confirmed cure for the COVID-19. Various plants and their components have been introduced against SARS-Co-2. A number of review articles have also been published on them. This article is focusing on the mechanistic aspects of these plants and their derivatives on SARS-CV-2. Method: The material in this review article was prepared from significant scientific databases, including Web of Science, PubMed, Science Direct, Scopus and Google Scholar. Results: Different medicinal plants and their phytocompounds interact with important structural and non-structural of SARS-CoV-2 proteins. Natural compounds form strong bonds with the active site of SARS-CoV-2 protease and make large conformational changes. These phytochemicals are potential inhibitors of structural and non-structural of SARS-CoV-2 proteins such as Spike protein, PLpro, and 3CLpro. Some important anti-SARS-CoV-2 actions of medicinal plants and their metabolites are inhibition of the virus replication or entry, blocking the angiotensin-converting enzyme 2 (ACE-2) receptor and “Transmembrane protease, serine 2 (TMPRSS2)” regulation of inflammatory mediators, inhibition of endothelial activation, toll-like receptors (TLRs) and activation of the nuclear factor erythroid-derived 2-related factor 2 (Nrf2). Some of these important natural immune boosters that are helpful for prevention and curing various symptoms related to COVID-19 include Allium sativum, Nigella sativa, Glycyrrhiza glabra Zingiber officinalis, Ocimum sanctum, Withania somnifera, Tinospora cordifolia, and Scutellaria baicalensis. Also, Kaempferol, Quercetin, Baicalin, Scutellarin, Glycyrrhizin, Curcumin, Apigenin, Ursolic acid, and Chloroquine are the best candidates for treating the symptoms associated with SARS-CoV-2 infection. Conclusion: Medicinal plants and/or their bioactive compounds with inhibitory effects against SARS-CoV-2 support the human immune system and help in fighting against COVID-19 and rejuvenating the immune system.

Rheumatoid Arthritis: History, Stages, Epidemiology, Pathogenesis, Diagnosis and Treatment

2017 ◽  
Vol 9 (02) ◽  
Author(s):  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim ◽  
Imad Hadi Hameed
Keyword(s):  
Rheumatoid Arthritis ◽  
Medicinal Plants ◽  
Systemic Disease ◽  
Modern Medicine ◽  
Whole Body ◽  
Internal Organs ◽  
Synthetic Drugs ◽  
Relieve Pain ◽  
Medicinal Treatment ◽  
Natural Drugs

The pharmacological mechanisms of the medicinal plants traditionally used for RA in Persian medicine are discussed in the current review. Further investigations are mandatory to focus on bioefficacy of these phytochemicals for finding novel natural drugs. Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and internal organs such as lungs, heart and eyes. Although numbers of synthetic drugs are being used as standard treatment for rheumatoid arthritis but they have adverse effect that can compromise the therapeutic treatment. Unfortunately, there is still no effective known medicinal treatment that cures rheumatoid arthritis as the modern medicine can only treat the symptoms of this disease that means to relieve pain and inflammation of joints. It is possible to use the herbs and plants in various forms in order to relieve the pain and inflammation in the joints. There are so many medicinal plants that have shown anti rheumatoid arthritis properties. So the plants and plant product with significant advantages are used for the treatment of rheumatoid arthritis. The present review is focused on the medicinal plants having anti rheumatoid arthritis activity

Ethnopharmacological Survey of Medicinal Plants Used in the Traditional Treatment of Female Infertility in Fez Region, Morocco

2019 ◽  
Vol 18 (5) ◽  
pp. 321-339 ◽  
Author(s):  
M. Slighoua ◽  
I. Mahdi ◽  
F. Ez-zahra Amrati ◽  
S. Boukhira ◽  
A. EL Hamsas EL Youbi ◽  
...  
Keyword(s):  
Reproductive Health ◽  
Medicinal Plants ◽  
Plant Species ◽  
Rosmarinus Officinalis ◽  
Female Infertility ◽  
Mentha Pulegium ◽  
Traditional Treatment ◽  
Lavandula Officinalis

An ethnopharmacological survey was carried out among 224 informants to collect the information on medicinal plants used for the traditional treatment of female infertility in the Fes, Meknes and Boulemane region. In total, 63 plant species belonging to 29 families were used against female infertility. The most frequently cited plants were Lavandula officinalis (26.33%), Mentha pulegium (13.83%), Mentha suaveolens (11.16%), Rosmarinus officinalis (10.71%) and Petroselinum sativum (8.03%). Furthermore, the present study represents a useful documentation for the preservation of this knowledge about medicinal plants and for the amelioration of women reproductive health.

Phytotherapy for wound healing: The most important herbal plants in wound healing based on Iranian etnobotanical documents

2020 ◽  
Vol 20 ◽  
Author(s):  
Kamal Solati ◽  
Mehrdad Karimi ◽  
Mahmoud Rafieian-Kopaei ◽  
Naser Abbasi ◽  
Saber Abbaszadeh ◽  
...  
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Aloe Vera ◽  
Datura Stramonium ◽  
New Drugs ◽  
Mentha Pulegium ◽  
Accelerate Wound Healing ◽  
Healing Tissue ◽  
Herbal Plants ◽  
Echium Amoenum

: Wound healing is a process which starts with inflammatory response after damage occurrence. This process happens by restoring the wound surface coating tissue, migrating fibroblasts to form the needed collagen, forming a healing tissue and finally contortion and extraction of the wound. Today, various drugs are used to heal the wound. However, the used drugs to repair wounds have some defects and side effects. In spite of all attempts to accelerate wound healing definitely, no safe drug has been introduced for this purpose. Therefore, the necessity of identifying herbal plants in ethnopharmacology and ethnobotany documents with healing effect is felt essential. In this article we tried to review and present Iranian effective medicinal plants and herbal compounds used for wound healing. Searching was performed on databases including ISI Web of Science, PubMed, PubMed Central, Scopus, ISC, SID, Magiran and some other databases. The keywords used included wound healing, skin treatment, medicinal plants, ethnobotany, and phytotherapy. In this regard, 139 effective medicinal plants on wound healing were identified based on ethnopharmacology and ethnobotanical sources of Iran. Medicinal plants such as Salvia officinalis, Echium amoenum, Verbascum spp., G1ycyrrhiza glabra, Medicago sativa, Mentha pulegium, Datura stramonium L., Alhagi spp., Aloe vera, Hypericum perforatum, Pistacia atlantica and Prosopis cineraria were the most important and effective medicinal plants on wound healing in Iran. These native Iranian medicinal plants are full of antioxidants and biological compounds and might be used for wound healing and preparation of new drugs.

An Evidence-Based Review of Antitussive Herbs Containing Essential Oils in Traditional Persian Medicine

2020 ◽  
Vol 17 ◽  
Author(s):  
Ayda Hosseinkhani ◽  
Bijan Ziaeian ◽  
Kamran Hessami ◽  
Mohammad Mehdi Zarshenas ◽  
Ali Kashkooe ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Essential Oils ◽  
Scientific Evidence ◽  
Herbal Remedies ◽  
Future Research ◽  
Evidence Based ◽  
Online Databases ◽  
Persian Medicine ◽  
Troublesome Symptom ◽  
Traditional Persian Medicine

Background: Cough is one of the most common medical symptoms for which medical advice is sought. Although cough is a protective reflex responsible for clearing the airways from secretions and foreign bodies, it can be a troublesome symptom that causes discomfort to patients. Due to the increasing interest in herbal remedies in the both developed and developing countries, in the current study, we aimed to overview medicinal herbs containing essential oils used as antitussive agents according to the Traditional Persian Medicine [TPM] textbooks. We summarized the relevant scientific evidence on their possible pharmacological actions. Methods: To collect the evidence for treatment of cough or “seaal” [cough in ancient books] from TPM sources, five main medicinal Persian manuscripts were studied. The antitussive herbs were listed and their scientific names were identified and authenticated in accordance with botanical reference books. ScienceDirect and PubMed online databases were searched for related mechanisms of action of the reported medicinal plants. Results: The number of 49 herbs containing essential oils were recommended in TPM for the treatment of cough; 21 of them had at least one known mechanism of action for cough suppression in the scientific literature. According to this review, most of the cited medicinal plants were assessed for either nitric oxide inhibitory or antitussive/expectorant activities. Conclusion: In addition to advantageous effects of antitussive herbs noted by TPM, the present review highlighted some recent evidence-based data on these promising candidates that could be used as an outline for future research on their medicinal use.

Persian herbal medicine in functional dyspepsia: a systematic review article.

2020 ◽  
Vol 17 ◽  
Author(s):  
Maryam Azimi ◽  
Mohammad Javad Zahedi
Keyword(s):  
Clinical Trials ◽  
Herbal Medicine ◽  
Functional Dyspepsia ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Crocus Sativus ◽  
Herbal Remedies ◽  
Asparagus Racemosus ◽  
Gastric Accommodation ◽  
Cynara Scolymus

Introduction: According to Rome IV, functional dyspepsia is diagnosed with presence of dyspepsia in the absence of organic or metabolic causes. FD caused by several factors such as impaired gastric accommodation and hypersensitivity to gastric distention. Several studies have reported effectiveness of herbal medicine on FD. This article, thus, reviews Persian herbal medicine in FD. Method: Electronic databases including Pubmed, Scopus, Cochrain, Embase, Web of science and Ovid were searched so as to find clinical articles related to dyspepsia and herbal medicine by July 2019. Our search strategies were traditional medicine, complementary and alternative medicine, herb, plant, and dyspepsia. We excluded all articles except Persian clinical trials. Results: We found 34 clinical trials with 15 herbs and 4 compound herbal remedies like Asparagus racemosus, Brassica oleracea, Cynara scolymus, Ocimum basilicum, Mentha longifolia, Mentha pulegium, Mentha piperata, Pimpinella anisum, Nigella sativa, Mastic gum, Curcuma longa, Pistatio atlantica, Glycyrrhiza glabra, Solanum tuberosum and Zingiber officinale and compound remedies of Rosa damascene & Crocus sativus, Trachyspermum copticom & Apium graveolence, Carum carvi & Mentha pipperata, Gingiber officinalis & Cynara scolymus are effective in functional dyspepsia. Conclusion: Many people use herbal and traditional remedies for treatment of disorders such as gastrointestinal disordersو , especially in Asian countries. Several studies reported the efficacy of herbal medicine in functional dyspepsia. Although their mechanisms are not fully understood, it seems they can modulate GI motility and improve symptoms of FD.

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