scholarly journals Galactorrhea among Female Mentally Ill Patients Using Antipsychotics in a Tertiary Institution in South-South Nigeria

2020 ◽  
Vol 6 ◽  
pp. 1
Author(s):  
Omamurhomu E Olose ◽  
Donald C Chukwujekwu ◽  
Cecilia O Busari ◽  
◽  
◽  
...  

Objective was to determine the prevalence of galactorrhea among respondents, to determine the correlation between the dose of antipsychotic and the presence of galactorrhea, to determine the relationship between the duration of drug use and the prolactin level, to determine the relationship between class of antipsychotic and galactorrhea, and to determine the predictors of galactorrhea among the respondents. This is a cross-sectional study. From 81 consenting patients taking prescribed antipsychotic medications and all of whom have met the inclusion criteria, a sociodemographic interview schedule was administered. Next, the venous blood sample was collected for the estimation of the serum prolactin level. The prevalence of galactorrhea was 50.6%, there was a correlation between galactorrhea and chlorpromazine equivalent dose of antipsychotics (r = 0.356, p = 0.001), there is an association between galactorrhea and the use of typical antipsychotics, there was also an association between the duration of antipsychotic use and galactorrhea, and the greatest predictor of galactorrhea was found to be the duration of antipsychotic medication usage. Galactorrhea can result from the use of atypical or typical antipsychotics, and the duration of antipsychotic use was the greatest predictor of galactorrhea.

Author(s):  
J. E. Egbagba ◽  
A. O. Abdu ◽  
N. Osegi ◽  
S. C. Amadi ◽  
M. A. Alex-Wele ◽  
...  

Aims: To determine rubella sero-prevalence (IgG, IgM) and to describe its relation to socio-demographic data among pregnant women in a tertiary institution in Yenagoa, Bayelsa state, South-South, Nigeria. Study Design:  This was a descriptive cross sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology, Federal Medical Centre in Yenegoa, Bayelsa State, in South-South Nigeria between May 2020 and August 2020. Methodology: We included 398 women at various stages of pregnancy. An interviewer administered questionnaire was used to obtain socio demographic data. Ten ml of venous blood was then collected for serological assays.  Analyses of samples were done using an in-vitro on-site rubella IgG/IgM rapid diagnostic assay. P value were kept at 0.05. Results: A total of 209 (53.0%) of the 398 women had a positive IgG antibodies. None (0.0%) of the women had positive IgM antibodies. There were no significant associations between respondents socio-demographic characteristics and rubella immunity as the probability values observed were greater than 0.05 (p>0.05). Conclusion: Our study shows a moderately high sero-prevalence of IgG antibodies amongst the participants studied. This indicates that rubella infection is endemic in Nigeria and requires further surveillance and control.


2018 ◽  
Vol 69 (9) ◽  
pp. 2438-2442
Author(s):  
Dana Maria Albulescu ◽  
Mara Carsote ◽  
Nina Ionovici ◽  
Adina Ghemigian ◽  
Mihaela Popescu ◽  
...  

5-hydroxytryptamine (5-HT) dually influences skeleton status through positive, indirect central effect and negative, direct, gut-associated impact. Circulating form is usually tested via venous blood sample. A limited number of clinical studies are published on this specific topic. We introduce a cross-sectional study on menopausal women with normal (N=29) and low bone mineral density (N=32) based on lumbar Dual-Energy X-Ray Absorptiometry (DXA) to whom serum serotonin was assessed and found no correlation with bone loss. This aspect confirms conflicting published data regarding the relationship between circulating levels and fracture risk assessment.


2020 ◽  
Vol 45 (6) ◽  
pp. 863-872
Author(s):  
Piotr Kuczera ◽  
Dorota Ciaston-Mogilska ◽  
Barbara Oslizlo ◽  
Anna Hycki ◽  
Andrzej Wiecek ◽  
...  

<b><i>Background:</i></b> Metabolic acidosis (MA) is one of the most common consequences of CKD. MA is also a risk factor of CKD progression and increased mortality in these patients. <b><i>Aim:</i></b> The aim of this retrospective, cross-sectional study was to assess the prevalence of MA in different stages of CKD and renal replacement therapy (RRT) modalities – haemodialysis (HD) and peritoneal dialysis (PD). Additionally, the relationship between the prevalence of MA and aetiology of kidney disease was analysed. <b><i>Methods:</i></b> One thousand five patients in different stages of CKD, or modalities of RRT were enrolled into this single-centre cross-sectional study. Forty-one patients were ruled out because of oral bicarbonate supplementation. In the remaining 964 patients (698 CKD stages 1–5, 226 HD, 40 PD), venous blood HCO<sub>3</sub><sup>−</sup> concentration, as well as serum Cr and urea concentrations were assessed. MA was diagnosed when blood HCO<sub>3</sub><sup>−</sup> concentration was below 22 mmol/L. <b><i>Results:</i></b> The prevalence of MA increased among all stages of CKD. Patients on HD had lower prevalence of MA in comparison with CKD 5 patients with no RRT (38.5 vs. 56.0%; <i>p</i> = 0.02) In PD patients, the prevalence of MA was significantly lower than in HD patients (2.5 vs. 38.5%; <i>p</i> &#x3c; 0.001). In the whole study group, there were no significant differences in the prevalence of MA between different aetiologies of CKD (glomerulonephritis 24%, hypertension 23%, diabetes 25%, and tubule-interstitial diseases 24%). Also, when only patients in stages CKD 3–5 were compared, no significant differences in the prevalence of acidosis were found (glomerulonephritis 28%, hypertension 22%, diabetes 24%, and tubule-interstitial 21%). <b><i>Conclusions:</i></b> (1) MA is more frequent in patients with more advanced stages of CKD. (2) RRT reduces the prevalence of MA. (3) In PD patients, MA is rare. (4) Aetiology of CKD seems not to have a significant impact on MA prevalence.


Author(s):  
Sanjay Badesara ◽  
Kiran Jakhar

Background: Infertility whether primary or secondary, has multi-factorial causation, out of which hormonal imbalance is one of the important factors. Current study evaluates the prevalence of hyperprolactinemia in infertile euthyroid women.Methods: After Ethics Committee approval and written informed consent, all infertile euthyroid women (n=153) with age group 20-40 years attending outpatient department of general hospital, with marriage duration of at least one year and willing to participate in study were recruited. Male factor infertility, women with diagnosed hyperprolactinemia, thyroid abnormality, tubal factors, any congenital anomaly of urogenital tract or obvious organic lesion or with history of anxiety or other psychological disorders and on treatment for same were excluded. Detailed obstetrics history with relevant laboratory, radiological investigations including serum prolactin level was done.Results: Mean serum prolactin level was 13.89±10.03 ng/ml. Out of 153 participants, 13 had hyperprolactinemia which comprised 8.50% of the sample. The mean of the level of serum prolactin level in primary infertility cases was 13.18±8.485 ng/ml while that in secondary infertility was 17.21±15.1 ng/ml. Primary infertility was approximately half (53.85%) in hyperprolactinemia group and majority (85%) in normoprolactinemia group. Duration of married life, infertility and fasting blood sugar were positively correlated with prolactin levels.Conclusions: Prevalence of hyperprolactinemia was 8.50% with higher serum prolactin level in secondary infertility as compared to primary infertility. So, estimation of serum prolactin levels in infertile patients with euthyroid status can help to a large extent in finding the cause of infertility and may help in further management.


Crisis ◽  
2011 ◽  
Vol 32 (5) ◽  
pp. 272-279 ◽  
Author(s):  
Allison S. Christian ◽  
Kristen M. McCabe

Background: Deliberate self-harm (DSH) occurs with high frequency among clinical and nonclinical youth populations. Although depression has been consistently linked with the behavior, not all depressed individuals engage in DSH. Aims: The current study examined maladaptive coping strategies (i.e., self-blame, distancing, and self-isolation) as mediators between depression and DSH among undergraduate students. Methods: 202 students from undergraduate psychology courses at a private university in Southern California (77.7% women) completed anonymous self-report measures. Results: A hierarchical regression model found no differences in DSH history across demographic variables. Among coping variables, self-isolation alone was significantly related to DSH. A full meditational model was supported: Depressive symptoms were significantly related to DSH, but adding self-isolation to the model rendered the relationship nonsignificant. Limitations: The cross-sectional study design prevents determination of whether a casual relation exists between self-isolation and DSH, and obscures the direction of that relationship. Conclusions: Results suggest targeting self-isolation as a means of DSH prevention and intervention among nonclinical, youth populations.


2019 ◽  
Vol 7 (2) ◽  
pp. 115
Author(s):  
Dini Yuliansari

The well is one of the source water used for bathing, washing, and drinking by the citizens in Jiken Hamlet, Rarang Village, Terara Sub-District. Poor dug well construction conditions can affect the amount of coliform bacteria contained in the dug well water. The purpose of this study is to identify the construction of dug wells and the content of coliform bacteria in dug well water and determine the relationship between dug well construction and the content of coliform bacteria. This research is analytic with a cross sectional study design. The results were obtained from 11 samples of dug wells which were observed in construction and the coliform content was known that all samples did not requirements as good dug well construction. Coliform content test results showed that as many as 5 dug well water samples did not pass the clean water quality standards. The results of data analysis with the chi-square test variable construction of dug wells with coliform content variable  showed 0,172 > 0,05, then the concluded is the dug well not suitable to use by people in that area as a source of water for daily needs.


2016 ◽  
pp. 41-45
Author(s):  
Lam Huong Le

Objectives: To study the relationship between serum estradiol and physical disorders after hysterectomy. Methods: A descriptive cross sectional study on 151 women after total hysterectomy from 12/2008 to 11/2010 at Hue Cental Hospial. Results: Serious disorders in total hysterectomy group include: physical disorders (34.78%), maternal disorders (71.74%), sexual disorders (58.70%). There were significant differences these disorders between total hysterectomy group and hysterectomy with/without accessiory remove group, as well as menopause group. Conclusion: Serum estradiol levels was inversely correlated with physical disorders, martenal disorders, sexual disorders and other disorders. Key words: hysterectomy, serum estradiol


Author(s):  
Dina Dewi Anggraini

ABSTRACT   The study aims todetermine the relationship between parenting style and the level of independence of Personal Hygiene Hand Wasting and Tooth Brush in Preschoolers in Kindergarten Negeri Pembina Blora in 2019. The study is a quantitative study, based on the research location including the type of field reseaerch, based on the ansence of the treatment of subjects including survey research, based on time is a cross sectional study, and based on objectives includin correlation analytics. The population in this study were all parents in Kindergarten Negeri Pembina Blora as many as 85 respondents. Based on the sample calculation, the sample obtained in this study that most parent in Kindergarten Negeri Pembina Blora amounted to 70 respondents. Srearmen’s rho test analysis results parenting parents with the level of independence of personal hygiene hand wasting result obtained p value = 0,000 < α (0,05), and parenting patters with the independence of personal hygiene tooth brush obtained results p value = 0,000 < α (0,05). So it can be concluded that were is a significant relationship between parenting parents with the level of independence of personal hygiene washing hands and brushing their tooth at preschoolers in Kindergarten Negeri Pembina Blora in 2019. Keywords: parenting; personal hygiene, preschool ABSTRAK   Penelitian ini bertujuan untuk mengetahui Hubungan Pola Asuh Orangtua Terhadap Tingkat Kemandirian Personal Hygiene Cuci Tangan dan Gogok Gigi pada Anak Prasekolah di TK Negeri Pembina Blora Tahun 2019. Penelitian ini adalah penelitian kuantitatif, berdasarkan tempat penelitian termasuk jenis penelitian lapangan, berdasarkan tidak adanya perlakuan terhadap subjek termasuk penelitian survey, berdasarkan waktu merupakan penelitian cross sectional, dan berdasarkan tujuan termasuk analitik korelasi. Populasi dalam penelitian ini adalah seluruh orangtua di TK Negeri Pembina Blora sebanyak 85 responden. Berdasarkan perhitungan sampel  maka diperoleh sampel pada penelitian ini adalah sebagian orangtua di TK Negeri Pembina Blora sebanyak 70 responden. Hasil analisis uji spearmen’s rho pola asuh orangtua dengan tingkat kemandirian personal hygiene cuci tangan didapatkan hasil p value = 0,000 < α (0,05), dan pola asuh orangtua dengan kemandirian personal hygiene gosok gigi didapatkan hasil p value = 0,000 < α (0,05). Sehingga dapat disimpulkan bahwa ada hubungan yang signifikan antara pola asuh orang tua dengan tingkat kemandirian personal hygiene cuci tangan dan gosok gigi pada anak prasekolah di TK Negeri Pembina Blora Tahun 2019. Kata kunci: pola asuh; personal hygiene; prasekolah


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