Morphological features of mucoperichondria in patients with post-traumatic deformity of nasal septum

2021 ◽  
Vol 19 (2) ◽  
pp. 56-64
Author(s):  
G. Yu. Tsarapkin ◽  
◽  
N. L. Kunel’skaya ◽  
O. V. Zairat’yants ◽  
A. S. Tovmasyan ◽  
...  
Keyword(s):  
Nasal Septum ◽  
Histological Study ◽  
Surgical Techniques ◽  
Morphological Features ◽  
Frequency Of Occurrence ◽  
Histological Findings ◽  
Nasal Breathing ◽  
The Past ◽  
Post Traumatic

Over the past decades, surgical techniques have been improved, aimed at restoring the position of the nasal septum in case of its deformities. The attitude to the technique of the operation itself has changed, which consists in a sparing approach to the osteochondral skeleton of the nasal septum (NS). It should be noted that to date, the histological features of the mucous membrane (MM) of NS have not been studied with pronounced curvatures of PN, in this regard, the purpose of our work was to conduct a histological study of the MM of NS and to identify the morphological features of the structure of mucoperichondria in the area of septal deformity. Research methods. Our study included 24 patients with nasal septum deviation (NSD) and concomitant vasomotor or hypertrophic rhinitis. All patients noted impaired nasal breathing. 12 men and women were examined, the average age of the patients was 36 ± 10 years. Patients with grade III of NSD according to the classification of Protasevich were examined and operated on. We analyzed the material taken from 5 loci of the MM of NS. A total of 120 histological sections were examined. When describing histological findings from loci A-E, we were guided by the frequency of occurrence of criteria indicating the severity of irreversible post-traumatic changes in MM of NS. After analyzing the material obtained and carrying out a comparative analysis of the frequency of occurrence of histological findings in each locus, we concluded that the proximity of the locus to the most deformed part of the nasal septum is characterized by the maximum severity of dystrophic and sclerotic changes in the MM of NS, similar to the histological picture of a hypertrophic scar.

Emendation of Fragilariophyceae classification (Bacillariophyta)

2015 ◽  
Vol 49 ◽  
pp. 75-91 ◽  
Author(s):  
V. A. Stepanova ◽  
R. M. Gogorev
Keyword(s):  
Historical Review ◽  
Systematic Position ◽  
Morphological Features ◽  
New Order ◽  
The Past ◽  
The Family ◽  
Molecular Studies

An historical review of some approaches to the classification of diatoms is presented. The class Fragilariophyceae was described by F. Round et al. (1990) and consisted of 54 genera of araphid diatoms. Over the past 25 years, 43 genera and two families within the class have been described. The systematic position of the family Plagiogrammaceae in the class of araphid diatoms was based on phylogenetic molecular studies. According to these data and unique morphological features, we propose a new order, Plagiogrammales ord. nov., with the type genus Plagiogramma. The name of the order Protoraphidales ord. nov. is validated, and the genus Podocystis is transferred from the family Fragilariaceae to the family Licmophoraceae. The systematic position of the genera Florella, Podocystis, Gato and Astrosyne is discussed.

Stress management: Corpus-based insights into vernacular interpretations of stress

2014 ◽  
Vol 10 (1) ◽  
pp. 81-93
Author(s):  
Laurel Smith Stvan
Keyword(s):  
Traumatic Stress ◽  
American English ◽  
Physical Symptom ◽  
The Body ◽  
Post Traumatic Stress ◽  
The Past ◽  
Academic Texts ◽  
Naturally Occurring ◽  
Post Traumatic ◽  
Semantic Shift

Examination of the term stress in naturally occurring vernacular prose provides evidence of three separate senses being conflated. A corpus analysis of 818 instances of stress from non-academic texts in the Corpus of Contemporary American English (COCA) and the Corpus of American Discourses on Health (CADOH) shows a negative prosody for stress, which is portrayed variously as a source outside the body, a physical symptom within the body and an emotional state. The data show that contemporary speakers intermingle the three senses, making more difficult a discussion between doctors and patients of ways to ‘reduce stress’, when stress might be interpreted as a stressor, a symptom, or state of anxiety. This conflation of senses reinforces the impression that stress is pervasive and increasing. In addition, a semantic shift is also refining a new sense for stress, as post-traumatic stress develops as a specific subtype of emotional stress whose use has increased in circulation in the past 20 years.

Second international scientific conference «Present fundamental problems of vegetation classification» (Yalta, 15–20 September 2019)

2019 ◽  
pp. 135-142
Author(s):  
K. V. Ivanova ◽  
A. M. Lapina ◽  
V. V. Neshataev
Keyword(s):  
Plant Communities ◽  
National Archive ◽  
Botanical Garden ◽  
Vegetation Classification ◽  
Scientific Conference ◽  
Scientific Journals ◽  
Time Dynamics ◽  
The Past ◽  
Research Organizations

The 2nd international scientific conference «Fundamental problems of vegetation classification» took place at the Nikitskiy Botanical Garden (Yalta, Republic of Crimea, Russia) on 15–20 September 2019. There were 56 participants from 33 cities and 43 research organizations in Russia. The conference was mostly focused on reviewing the success in classification of the vegetation done by Russian scientists in the past three years. The reports covered various topics such as classification, description of new syntaxonomical units, geobotanical mapping for different territories and types of vegetation, studies of space-time dynamics of plant communities. The final discussion on the last day covered problems yet to be solved: establishment of the Russian Prodromus and the National archive of vegetation, complications of higher education in the profile of geobotany, and the issue of the data leakage to foreign scientific journals. In conclusion, it was announced that the 3rd conference in Nikitskiy Botanical Garden will be held in 2022.

Changes in the parameters of nasal breathing and parameters of the upper respiratory tract during orthognathic operations in patients with II and III skeletal class of jaw anomalies

2020 ◽  
pp. 22-27
Author(s):  
S.Sh. Gammadaeva ◽  
M.I. Misirkhanova ◽  
A.Yu. Drobyshev
Keyword(s):  
Respiratory Tract ◽  
Nasal Cavity ◽  
Nasal Septum ◽  
Cross Sectional Area ◽  
Upper Respiratory Tract ◽  
Sectional Area ◽  
Nasal Breathing ◽  
Cross Sectional ◽  
Skeletal Class ◽  
Upper Respiratory

The study analyzed the functional parameters of nasal breathing, linear parameters of the nasal aperture, nasal cavity and nasopharynx, volumetric parameters of the upper airways in patients with II and III skeletal class of jaw anomalies before and after orthognathic surgery. The respiratory function of the nose was assessed using a rhinomanometric complex. According to rhinoresistometry data, nasal resistance and hydraulic diameter were assessed. According to the data of acoustic rhinometry, the minimum cross-sectional area along the internal valve, the minimum cross-sectional area on the head of the inferior turbinate and nasal septum and related parameters were estimated. According to the CBCT data, the state of the nasal septum, the inferior turbinates, the nasal aperture, the state of the nasal cavity, and the linear values of the upper respiratory tract (nasopharynx) were analyzed. The patients were divided into 4 groups according to the classification of the patency of the nasal passages by

The Poetry and Music of Science

2019 ◽  
Author(s):  
Tom McLeish
Keyword(s):  
School Leaver ◽  
Creative People ◽  
Creative Processes ◽  
Arts And Sciences ◽  
The Past ◽  
The Arts ◽  
The Two Cultures ◽  
Personal Accounts ◽  
Poetry And Music

‘I could not see any place in science for my creativity or imagination’, was the explanation, of a bright school leaver to the author, of why she had abandoned all study of science. Yet as any scientist knows, the imagination is essential to the immense task of re-creating a shared model of nature from the scale of the cosmos, through biological complexity, to the smallest subatomic structures. Encounters like that one inspired this book, which takes a journey through the creative process in the arts as well as sciences. Visiting great creative people of the past, it also draws on personal accounts of scientists, artists, mathematicians, writers, and musicians today to explore the commonalities and differences in creation. Tom McLeish finds that the ‘Two Cultures’ division between the arts and the sciences is not after all, the best classification of creative processes, for all creation calls on the power of the imagination within the constraints of form. Instead, the three modes of visual, textual, and abstract imagination have woven the stories of the arts and sciences together, but using different tools. As well as panoramic assessments of creativity, calling on ideas from the ancient world, medieval thought, and twentieth-century philosophy and theology, The Poetry and Music of Science illustrates its emerging story by specific close-up explorations of musical (Schumann), literary (James, Woolf, Goethe) mathematical (Wiles), and scientific (Humboldt, Einstein) creation. The book concludes by asking how creativity contributes to what it means to be human.

scholarly journals Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms

2021 ◽  
Vol 73 (2) ◽  
pp. 323-345
Author(s):  
Samuel Kohtala
Keyword(s):  
Traumatic Stress ◽  
Molecular Mechanisms ◽  
Post Traumatic Stress ◽  
Active Metabolites ◽  
The Past ◽  
Antidepressant Effects ◽  
Post Traumatic ◽  
Pharmacologically Active ◽  
Dose Dependent ◽  
Different Doses

AbstractOver the past 50 years, ketamine has solidified its position in both human and veterinary medicine as an important anesthetic with many uses. More recently, ketamine has been studied and used for several new indications, ranging from chronic pain to drug addiction and post-traumatic stress disorder. The discovery of the rapid-acting antidepressant effects of ketamine has resulted in a surge of interest towards understanding the precise mechanisms driving its effects. Indeed, ketamine may have had the largest impact for advancements in the research and treatment of psychiatric disorders in the past few decades. While intense research efforts have been aimed towards uncovering the molecular targets underlying ketamine’s effects in treating depression, the underlying neurobiological mechanisms remain elusive. These efforts are made more difficult by ketamine’s complex dose-dependent effects on molecular mechanisms, multiple pharmacologically active metabolites, and a mechanism of action associated with the facilitation of synaptic plasticity. This review aims to provide a brief overview of the different uses of ketamine, with an emphasis on examining ketamine’s rapid antidepressant effects spanning molecular, cellular, and network levels. Another focus of the review is to offer a perspective on studies related to the different doses of ketamine used in antidepressant research. Finally, the review discusses some of the latest hypotheses concerning ketamine’s action.

scholarly journals ANCA Status or Clinical Phenotype — What Counts More?

2021 ◽  
Vol 23 (6) ◽  
Author(s):  
Martin Windpessl ◽  
Erica L. Bettac ◽  
Philipp Gauckler ◽  
Jae Il Shin ◽  
Duvuru Geetha ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Granulomatosis With Polyangiitis ◽  
Clinical Phenotype ◽  
Antineutrophil Cytoplasmic Antibody ◽  
Cardiovascular Death ◽  
Genetic Associations ◽  
Ongoing Debate ◽  
The Past ◽  
Anca Associated Vasculitis

Abstract Purpose of Review There is ongoing debate concerning the classification of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. That is, whether classification should be based on the serotype (proteinase 3 (PR3)- or myeloperoxidase (MPO)-ANCA) or on the clinical phenotype (granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA)). To add clarity, this review focused on integration of the most recent literature. Recent Findings Large clinical trials have provided evidence that a serology-based risk assessment for relapses is more predictive than distinction based on the phenotype. Research conducted in the past decade indicated that a serology-based approach more closely resembles the genetic associations, the clinical presentation (i.e., lung involvement), biomarker biology, treatment response, and is also predicting comorbidities (such as cardiovascular death). Summary Our review highlights that a serology-based approach could replace a phenotype-based approach to classify ANCA-associated vasculitides. In future, clinical trials and observational studies will presumably focus on this distinction and, as such, translate into a “personalized medicine.”

scholarly journals Morphological Characteristics, Classifications and Difficulties in the Use of Diagnostic Criteria for Serrated Lesions of the Large Intestine

2021 ◽  
Author(s):  
Cesar de Souza Bastos Junior ◽  
Vera Lucia Nunes Pannain ◽  
Adriana Caroli-Bottino
Keyword(s):  
Diagnostic Criteria ◽  
Morphological Characteristics ◽  
World Health ◽  
Diagnostic Tools ◽  
Serrated Adenoma ◽  
The Past ◽  
The World ◽  
Serrated Lesions ◽  
Health Organization

Abstract Introduction Colorectal carcinoma (CRC) is the most common gastrointestinal neoplasm in the world, accounting for 15% of cancer-related deaths. This condition is related to different molecular pathways, among them the recently described serrated pathway, whose characteristic entities, serrated lesions, have undergone important changes in their names and diagnostic criteria in the past thirty years. The multiplicity of denominations and criteria over the last years may be responsible for the low interobserver concordance (IOC) described in the literature. Objectives The present study aims to describe the evolution in classification of serrated lesions, based on the last three publications of the World Health Organization (WHO) and the reproducibility of these criteria by pathologists, based on the evaluation of the IOC. Methods A search was conducted in the PubMed, ResearchGate and Portal Capes databases, with the following terms: sessile serrated lesion; serrated lesions; serrated adenoma; interobserver concordance; and reproducibility. Articles published since 1990 were researched. Results and Discussion The classification of serrated lesions in the past thirty years showed different denominations and diagnostic criteria. The reproducibility and IOC of these criteria in the literature, based on the kappa coefficient, varied in most studies, from very poor to moderate. Conclusions Interobserver concordance and the reproducibility of microscopic criteria may represent a limitation for the diagnosis and appropriate management of these lesions. It is necessary to investigate diagnostic tools to improve the performance of the pathologist's evaluation, for better concordance, and, consequently, adequate diagnosis and treatment.

scholarly journals Application of Artificial Intelligence in Food Industry—a Guideline

2021 ◽  
Author(s):  
Nidhi Rajesh Mavani ◽  
Jarinah Mohd Ali ◽  
Suhaili Othman ◽  
M. A. Hussain ◽  
Haslaniza Hashim ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Intelligent Systems ◽  
Food Industry ◽  
Near Infrared ◽  
Vision System ◽  
Electronic Tongue ◽  
World Population ◽  
Computer Vision System ◽  
The Past

AbstractArtificial intelligence (AI) has embodied the recent technology in the food industry over the past few decades due to the rising of food demands in line with the increasing of the world population. The capability of the said intelligent systems in various tasks such as food quality determination, control tools, classification of food, and prediction purposes has intensified their demand in the food industry. Therefore, this paper reviews those diverse applications in comparing their advantages, limitations, and formulations as a guideline for selecting the most appropriate methods in enhancing future AI- and food industry–related developments. Furthermore, the integration of this system with other devices such as electronic nose, electronic tongue, computer vision system, and near infrared spectroscopy (NIR) is also emphasized, all of which will benefit both the industry players and consumers.

Small Bowel Obstruction

2010 ◽  
Vol 21 (2) ◽  
pp. 187-194
Author(s):  
Colleen Trevino
Keyword(s):  
Small Bowel ◽  
Physical Examination ◽  
Surgical Intervention ◽  
Signs And Symptoms ◽  
Bowel Ischemia ◽  
Key Factors ◽  
The Past ◽  
Factors Influencing ◽  
Imaging Response

Strategies for the management of small bowel obstructions have changed significantly over the years. Nonoperative medical management has become the mainstay of treatment of many small bowel obstructions. However, the key to the management of small bowel obstructions is identifying those patients who need surgical intervention. Identification of those at risk for bowel ischemia and bowel death is an art as much as it is a science. Using the current literature and the past knowledge regarding small bowel obstructions, the clinician must carefully identify the signs and symptoms that suggest the need for operative intervention. Classification of the obstruction, history and physical examination, imaging, response to decompression and resuscitation, and resolution or progression of symptoms are the key factors influencing the management of small bowel obstructions.

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