Impairment induced due to oganophosphate compounds in some blood biochemical indices of fingerlings of Cyprinus carpio var. communis

2019 ◽  
Author(s):  
Imtiyaz Qayoom ◽  
Masood H. Balkhi ◽  
Feroz A. Shah ◽  
Bilal A. Bhat
Keyword(s):  
Cyprinus Carpio ◽  
Serum Glucose ◽  
Toxicity Tests ◽  
Control Group ◽  
Organophosphate Pesticides ◽  
Serum Globulin ◽  
Range Finding ◽  
Blood Biochemical ◽  
Biochemical Indices ◽  
Blood Biochemical Indices

Present study was aimed to investigate the effects of two organophosphate pesticides (dimethoate and chlorpyrifos) on some blood biochemical parameters of juveniles common carps (Cyprinus carpio var. communis). Fingerlings were subjected to bioassays divided into 5 experimental groups in range finding test on the basis of which the doses for definitive tests were selected. The acute bioassay toxicity tests were carried out in triplicates for 96 hours with a control group run parallel to the experiment. Data obtained was analyzed as per Finney’s probit to determine LC50 values. The mean lethal concentration (LC50) values for dimethoate and chlorpyrifos were found 1.1ppm and 3.8ppb respectively. The samples were investigated for various blood biochemical indices such as total protein (TP), serum albumin (SA), serum globulin (SGLO), alanine aminotransferase (ALT), asphartate aminotransferase (AAT), serum bilirubin (SB), serum glucose (SGLU), serum cholesterol (SC), and lactate dehydrogenase (LDH). All the liver enzymes (AAT, ALT, SB and LDH) and glucose (SGLU) were found increased while as TP, SA, SGLO, SB and SC were found decreased than the normal. Chlorpyrifos, was however, found to alter the biochemical indices more profoundly than dimethoate. The results indicated the organophosphate pesticides are intensely harmful for fish health. Their entry to natural waterbodies must be stopped besides ensuring their judicious application around the catchment area.

scholarly journals HE GROWTH RATE AND BLOOD BIOCHEMICAL INDICES OF PIGS WHEN USING LIPOKAR FEED SUPPLEMENT

2021 ◽  
pp. 54-60
Author(s):  
I.A. Pushkarev ◽  
◽  
S.V. Burtseva ◽  
N.A. Novikov ◽  
N.M. Ponamarev ◽  
...  
Keyword(s):  
Growth Rate ◽  
Live Weight ◽  
Control Group ◽  
Trial Group ◽  
Feed Supplement ◽  
Altai Region ◽  
Blood Biochemical ◽  
Research Goal ◽  
Biochemical Indices ◽  
Blood Biochemical Indices

The studies were conducted in 2015 on Large Whitepigs of the breeding farm of the AO “Linevskiy plemzavod” (Altai Region, Smolenskiy District). The research goal was to determine the growth rate and blood biochemical indices of pigs when using LipoKar feed supplement.According to the design of the experiment, the animals of the control group were fed the basic dietonly. In the trial group, the sows received LipoKar feed supplement for 20 days startingfrom the 85th day of pregnancy. Then, the piglets born from them were also fed LipoKar feed supplement during the nursery period for 40 days in a 10 days’ interval. The dosages of the feed supplement were as following: for pregnant sows -2.1 g perhead per day; for young animals -0.8 g per head per day. The following effects of using LipoKar feed supplementwere found in the trial group: increasing piglet live weight from 4.2% to 11.7% (p < 0.001), average daily live weight gains -from 3.4% to 18.6% (p < 0.05); total protein, vitamin A and alkaline re-servein blood serum by 15.5% (p < 0.001), 9.2% (p < 0.05) and 20.9% (p < 0.001), respectively

scholarly journals BLOOD BIOCHEMICAL INDICES OF SEED BULLS WHEN USING MINERAL SUPPLEMENT BASED ON MARAL ANTLER PRESS-CAKE

2021 ◽  
pp. 44-51
Author(s):  
A.I. Afanasyeva ◽  
◽  
V.A. Sarychev ◽  
S.N. Chebakov ◽  
◽  
...  
Keyword(s):  
Press Cake ◽  
Good Health ◽  
Biologically Active ◽  
Control Group ◽  
Trial Group ◽  
Mineral Supplement ◽  
Genetic Characteristics ◽  
Blood Biochemical ◽  
Biochemical Indices ◽  
Blood Biochemical Indices

The seed bulls used for artificial insemination should be in good health, have outstanding genetic characteristics, have high sexual activity, and the biological products ob-tained from them should have high quality indices. One of the possible methods of increasing semen production is the introduction of dietary supplements into the diet. The intro-duction of new feed and biologically active supplements into the diet may cause both positive and negative changes in metabolic processes. Monitoring the biochemical status of blood allows detecting not only metabolic disorders in highly productive animals but also a lack of vitamins, mac-ro-and microelements. The research goal was to study the effect of a natural biostimulant (mineral supplement) made from maral antler press-cake on the blood biochemical indices ofBlack Pied seed bulls in the breeding company AO “Plempredpriyatiye Barnaulskoye”. Along with the basic diet, the seed bulls of the trial group received the natural biostimulant (mineral supplement) based on maral antler press-cake; the daily dose -15.0 g per head, for 30 days with 10 days’ interval after each application. The supple-ment was thoroughly mixed with compound feed before feeding. The mineral supplement is of powder form and contains a complex of vitamins, minerals, amino acids and other biologically active substances. The use of a mineral supplement increased the amount of total protein and al-bumin by 7.15% and 18.3%, respectively. The blood glu-cose level in the seed bulls of the trial group was higher by 12% and cholesterol by 17.1% than in the blood of the con-trol group animals. Cholesterol of the seed bulls may be used as a structural material or a precursor in the synthesis of sex steroid hormones. The level of total calcium, alkaline reserve at the end of the experiment increased in the seed bulls when using the mineral supplement made from maral antler press-cake in the diet by 4.8% and 8.1%, respective-ly, as compared to the control group.

Toxicological evaluation and effects of oganophosphate compounds on hematological profile of juvenile common carps (Cyprinus carpio var. Communis)

2018 ◽  
Author(s):  
Imtiyaz Masood H. Balkhi, Feroz A. Shah Qayoom ◽  
Masood Feroz A. Shah and Bilal A. Bhat H Balkhi ◽  
Feroz A. Shah ◽  
Bilal A. Bhat
Keyword(s):  
Blood Cell ◽  
Cyprinus Carpio ◽  
Negative Impact ◽  
Haemoglobin Concentration ◽  
Toxicity Tests ◽  
Control Group ◽  
Toxicological Evaluation ◽  
Range Finding ◽  
Haematological Profile ◽  
The Mean

Present study was carried out to investigate the alterations in the haematological profile of juvenile common carp (Cyprinus carpio var. communis) against acute toxicity of organophosphorous compounds, dimethoate and chlorpyrifos. The fish were divided into 5 different experimental groups for range finding tests on the basis of which the doses for definitive tests were selected. The acute bioassay toxicity tests were carried out in triplicates for 96 hours with a control group run parallel to the experiment. Data obtained was analyzed as per Finney’s probit to determine LC50 values. The mean lethal concentration was found 1.1ppm and 3.8ppb respectively for dimethoate and chlorpyrifos. The samples investigated for various haematological parameters such as haemoglobin concentration (Hb), Red blood cell (TEC) and White blood cell (TLC and DLC) counts the heamatocrit (Ht) level, the mean corpuscular volume (MCV) and the mean corpuscular haemoglobin (MCH). Packed cell volume (PCV) and Erythrocyte sedimentation rate (ESR) showed a negative impact of pesticide treated fishes when compared with control. Hb, TEC and Ht were found lower while as ESR and TLC were recorded higher than the control specimens. MCV and MCH showed statistically insignificant differences when compared with control. In DLC, monocyte lymphocyte, neutrophil and basophils were found increased while as eosinophil count was found unaffected than the normal. Studies suggested that the pesticides are potential toxicants for common carps among which chlorpyrifos was found to elicit profound changes intense than dimethoate.

Effect of Chelated Mineral Mixture on Blood Biochemistry, Hormone and Mineral Status in Repeat Breeder Buffaloes in Tribal Areas of Dahod District in Gujarat, India

2019 ◽  
Vol 15 (01) ◽  
pp. 40-44 ◽  
Author(s):  
P M Joshi ◽  
D Patel ◽  
P D Patel
Keyword(s):  
Treatment Group ◽  
Experimental Period ◽  
Serum Glucose ◽  
Blood Biochemistry ◽  
Control Group ◽  
Blood Collection ◽  
Mineral Status ◽  
Blood Biochemical ◽  
Mineral Mixture ◽  
Repeat Breeder

An on-farm trial for 90 days was conducted at four tribal villages to assess the effect of chelated mineral mixture (CMM) supplementation on blood biochemistry as well as hormonal and mineral status, nutrient intake and reproductive performance of the repeat breeder buffaloes (n = 24). The animals selected were randomly divided into two groups of 12 animals each. The group T1 was control group (farmer’s feeding schedule), and T2 treatment group (T1 + CMM @ 50 g/animal/day). Blood collection was done at 0, 45 and 90 days of the experiment from both the groups for assessment of blood biochemical, hormonal and mineral status of the animals. Average DM, DCP and TDN intake in repeat breeder buffaloes calculated as per information collected from farmers were statistically similar among both the groups and were as per ICAR requirements of animals. Results revealed significant (p less than 0.05) improvement in hemoglobin, serum glucose, total protein, total cholesterol, progesterone, and macro (Ca, P)–micro (Zn, Fe, Cu, Co, Mn) mineral status of chelated mineral supplemented group as compared to control animals. The number of days taken for a successful conception in repeat breeder buffaloes as well as the cost of feeding was also reduced upon supplementation of CMM in T2 as compared to T1 group. The control group recorded a 22.12% higher cost of rearing than the treatment group during the experimental period. The findings revealed the beneficial role of cheated minerals supplementation in improving health, nutritional and reproductive status of repeat breeding buffaloes.

GCdiscrimination: identification of gastric cancer based on a milliliter of blood

2020 ◽  
Author(s):  
Jiangpeng Wu ◽  
Yifan Yang ◽  
Long Cheng ◽  
Jing Wu ◽  
Lili Xi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Identification System ◽  
Clinical Value ◽  
Liquid Biopsies ◽  
Innovative Strategy ◽  
Blood Indices ◽  
Routine Blood ◽  
Blood Biochemical ◽  
Biochemical Indices ◽  
Blood Biochemical Indices

Abstract Gastric cancer (GC) continues to be one of the major causes of cancer deaths worldwide. Meanwhile, liquid biopsies have received extensive attention in the screening and detection of cancer along with better understanding and clinical practice of biomarkers. In this work, 58 routine blood biochemical indices were tentatively used as integrated markers, which further expanded the scope of liquid biopsies and a discrimination system for GC consisting of 17 top-ranked indices, elaborated by random forest method was constructed to assist in preliminary assessment prior to histological and gastroscopic diagnosis based on the test data of a total of 2951 samples. The selected indices are composed of eight routine blood indices (MO%, IG#, IG%, EO%, P-LCR, RDW-SD, HCT and RDW-CV) and nine blood biochemical indices (TP, AMY, GLO, CK, CHO, CK-MB, TG, ALB and γ-GGT). The system presented a robust classification performance, which can quickly distinguish GC from other stomach diseases, different cancers and healthy people with sensitivity, specificity, total accuracy and area under the curve of 0.9067, 0.9216, 0.9138 and 0.9720 for the cross-validation set, respectively. Besides, this system can not only provide an innovative strategy to facilitate rapid and real-time GC identification, but also reveal the remote correlation between GC and these routine blood biochemical parameters, which helped to unravel the hidden association of these parameters with GC and serve as the basis for subsequent studies of the clinical value in prevention program and surveillance management for GC. The identification system, called GC discrimination, is now available online at http://lishuyan.lzu.edu.cn/GC/.

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