Effects of Plantago major extract on serum levels of antioxidant vitamins and minerals in broiler

2018 ◽  
Author(s):  
S. Dede ◽  
N. T. Bingol ◽  
D. Kilicalp Kilinc ◽  
Y. Deger ◽  
Ý. H. Yoruk ◽  
...  
Keyword(s):  
Vitamin D ◽  
Control Diet ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Antioxidant Vitamin ◽  
Broiler Chicks ◽  
Plantago Major ◽  
Serum Vitamin D ◽  
Zinc Levels ◽  
Iron Manganese

The aim of this study was to evaluate the effects of Plantago major liquid extract on serum antioxidant vitamin and mineral concentrations of broiler. The experiment consisted of the control and 2 treatment groups, composed of 28 Ross 308 broiler chicks (Total, 84). A basal (control) diet was formulated. P. Major was added to the control diet as following: PM1 (5 g/kg feed), PM2 (10 g/kg feed). The chicks were feed for 42 days ad libitum. The serum micronutrients (Retinol, á-tocopherol, vitamin D, calcium, magnesium, iron, manganese, and zinc) levels were determined. The retinol, á-tocopherol, Fe, Mg, Mn levels were not affected, and the Zn levels decreased in the PM1 and PM2. The supplementation of P. major has affected the serum vitamin D and Zn levels for this study, and should be analyzed for the alterations on the metabolism in subsequent studies.

Relationship between HOMA-IR and serum vitamin D in Chinese children and adolescents

2016 ◽  
Vol 29 (7) ◽  
Author(s):  
Lingli Wang ◽  
Huiyan Wang ◽  
Huaikai Wen ◽  
Hongqun Tao ◽  
Xiaowei Zhao
Keyword(s):  
Vitamin D ◽  
Children And Adolescents ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Chinese Children ◽  
Model Assessment ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
The Difference ◽  
Chinese Children And Adolescents

AbstractThe objective of this study was to examine the cross-sectional relationship between homeostasis model assessment for insulin resistance (HOMA-IR) and serum 25-hydroxyvitamin D (25-OHD) level in Chinese children and adolescents.Anthropometric indices, lipid metabolic profile, and serum levels of glucose, insulin and 25-OHD were determined among 278 healthy prepubertal and pubertal, normal and overweight/obese children and adolescents aged 8–18 years between March 2014 and February 2015.HOMA-IR was significantly different across vitamin D statuses (p<0.001), even after adjusting for body mass index (BMI) (p=0.035) and waist-to-height ratio (p=0.044); the difference was not significant between the vitamin D deficient and insufficient groups (p=0.120). HOMA-IR negatively correlated with serum 25-OHD level for all subjects (ROur findings supported that lower vitamin D status is strongly associated with worse HOMA-IR.

scholarly journals No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

2017 ◽  
Vol 75 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Yara Dadalti Fragoso ◽  
Tarso Adoni ◽  
Soniza Vieira Alves-Leon ◽  
Samira L. Apostolos-Pereira ◽  
Walter Oleschko Arruda ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Large Population ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Serum Vitamin D ◽  
Control Subjects ◽  
Vitamin D Levels ◽  
The Mean ◽  
25 Oh Vitamin D

ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration. Conclusion: At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.

Distinct Association of Serum Vitamin D Concentration with Disease Activity and Trough Levels of Infliximab and Adalimumab during Inflammatory Bowel Disease Treatment

Digestion ◽  
2019 ◽  
Vol 101 (6) ◽  
pp. 761-770
Author(s):  
Nicolae-Catalin Mechie ◽  
Eirini Mavropoulou ◽  
Volker Ellenrieder ◽  
Steffen Kunsch ◽  
Silke Cameron ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Bowel Disease ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Tnf Α ◽  
Inflammatory Bowel ◽  
Biochemical Remission ◽  
Zinc Levels ◽  
Trough Levels

<b><i>Background:</i></b> Studies of serum vitamin D (Vit-D) levels in patients with inflammatory bowel disease (IBD) treated with anti-tumor necrosis factor-alpha (anti-TNF-α) agents are scarce. The conjunction of Vit-D as well as zinc levels and anti-TNF-α-trough concentrations (TC) has not yet been explored. <b><i>Objectives:</i></b> To determine the association of serum Vit-D, zinc and C-reactive protein (CRP) levels with clinical and biochemical remission and a possible correlation with serum TC and antibody levels of anti-TNF-α. <b><i>Methods:</i></b> Serum Vit-D and zinc levels as well as Infliximab (IFX) and Adalimumab (ADA) TC during the maintenance phase of treatment were measured in 112 IBD patients. Statistical analysis were performed for clinical and biochemical remission. <b><i>Results:</i></b> Vit-D and zinc deficiency were detected in 58 and 4.5% of the patients respectively. In IFX-treated patients, IFX-TC, Vit-D and CRP levels were associated independently with clinical remission with an OR of 20 (95% CI 1.3–333, <i>p</i> = 0.03), 1.3 (95% CI 1.1–1.7, <i>p</i> = 0.02) and 0.4 (95% CI 0.2–0.8, <i>p</i> = 0.01) respectively. Serum IFX-TC and Vit-D levels correlated positively (<i>r</i> = 0.39, <i>p</i> = 0.001), while serum IFX-TC and CRP levels showed an inverse correlation (<i>r</i> = –0.43, <i>p</i> &#x3c; 0.001). Only ­IFX-TC associated independently with biochemical remission with a threshold of 3.1 µg/mL. In ADA-treated patients, ADA-TC associated independently with clinical and biochemical remission with an OR of 2.5 (95% CI 1.1–5.0, <i>p</i> = 0.04) and 1.3 (95% CI 1.1–1.4, <i>p</i> = 0.03) respectively. The serum zinc level was associated neither with clinical nor with biochemical remission in either cohort. <b><i>Conclusions:</i></b> Our results indicate that serum Vit-D level may be a predictive marker in addition to drug trough levels in IBD patients treated with IFX. Furthermore, due to the correlation between serum IFX and Vit-D levels, Vit-D substitution should be conducted in patients with low Vit-D levels.

scholarly journals Deficiency of Vitamin D in Allergic Rhinitis: A Possible Factor in Multifactorial Disease

2014 ◽  
Vol 7 (3) ◽  
pp. 112-116
Author(s):  
Anil Jain ◽  
Pankaj Shah ◽  
Datt Modh ◽  
Bhaskar Thakkar ◽  
Ashish Katarkar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Allergic Rhinitis ◽  
Normal Population ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Multifactorial Disease ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Immunological Effects ◽  
K Deficiency

ABSTRACT Allergic rhinitis is a common condition affecting 5 to 40% of general population and its prevalence is increasing. It is a chronic condition characterized by inflammation of nasal mucosa. As per recent studies, there is an association between serum vitamin D levels and allergic rhinitis status. Vitamin D has major role in the regulation of calcium metabolism. In addition to this, it also has a number of immunological effects and takes part in immunomodulation, which can significantly affect the outcome of allergic responses like in allergic rhinitis. Aims and objectives To establish the correlation between vitamin D3 serum levels and allergic rhinitis. Materials and methods Vitamin D levels were assessed in 23 patients with allergic rhinitis diagnosed clinically by allergic rhinitis and its impact on asthma 2008 criteria and results were compared with vitamin D status in the normal population of same region. Results The levels of serum vitamin D levels were significantly low in the patients of allergic rhinitis. Conclusion Measuring of serum levels of vitamin D could be considered in the routine assessment of patients with allergic rhinitis. How to cite this article Thakkar B, Katarkar A, Modh D, Jain A, Shah P, Joshi K. Deficiency of Vitamin D in Allergic Rhinitis: A Possible Factor in Multifactorial Disease. Clin Rhinol An Int J 2014;7(3):112-116.

scholarly journals The role of vitamin D in multisystem sarcoidosis / Uloga vitamina D u sarkoidozi

2012 ◽  
Vol 31 (4) ◽  
pp. 339-346 ◽  
Author(s):  
Violeta Mihailović-Vučinić ◽  
Svetlana Ignjatović ◽  
Aleksandra Dudvarski-Ilić ◽  
Mihailo Stjepanović ◽  
Mira Vuković ◽  
...  
Keyword(s):  
Vitamin D ◽  
Chronic Disease ◽  
Patient Group ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Forced Expiratory Volume ◽  
Published Data ◽  
Chi Square ◽  
Serum Vitamin D ◽  
Fatigue Syndrome

Summary Recently published data indicate that vitamin D abnormalities are common in sarcoidosis patients. The purpose of this study was to compare serum vitamin 25(OH)D levels among sarcoidosis patients with different clinical cour - ses of the disease. The study also included the first observations on cognitive functions (i.e. depression and fatigue syndrome) in relation to vitamin D deficiency in sarcoidosis patients. At the Biochemical Laboratory of the Clinical Center of Serbia, Belgrade, vitamin D25(OH)D was measured using the Elecsys® Vitamin D total test. A total of 226 patients with biopsy-positive sarcoidosis were analyzed. The average median value of serum vitamin D was 9.47 mg/L, suggesting severe deficiency. Statistically significant correlation was found in patients with chronic disease and low levels of serum vitamin 25(OH)D (Chi-Square=6.044; df=2; p=0.014). The patient group with vitamin D serum levels higher than 20 mg/L showed higher levels of the mean forced vi tal capacity (FVC) by 380 mL, and forced expiratory volume in one second (FEV1) by 220 mL, when compared to the patient group with lower serum vitamin D. A statistically significant role was established for serum vitamin 25(OH)D levels as the predictor of fatigue (R2=0.878; p=0.038 (b=0.216)) and depression in patients with sarcoidosis (R2=0.80; p=0.000 (b=0.391)). The insufficiency of 25(OH)D seems to be an important factor in predicting the course of chronic disease, significant lung function impairments and cognitive failures such as fatigue and depression. The fact that the majo rity of the analyzed sarcoidosis patients had totally deficient serum 25(OH)D levels made this finding even more notable.

scholarly journals Serum vitamin D content in children with SARS-CoV-2 infection

2021 ◽  
Vol 6 ◽  
pp. 79-82
Author(s):  
V.N. Peregoedova ◽  
◽  
I.K. Bogomolova ◽  
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Clinical Symptoms ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Control Group ◽  
Immunochemical Method ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
25 Hydroxyvitamin D

Aim of study. To study the total level of 25-hydroxyvitamin D in children with SARS-CoV-2 infection (COVID-19). Material and мethods. A total of 82 children aged 0-17 diagnosed with SARS-CoV-2 infection were enrolled. Depending on the severity of clinical symptoms, all children were divided into three groups according to the COVID-19 severity: asymptomatic, mild and moderate. The serum level of vitamin D in all patients was tested via the immunochemical method. Results. It was found that children with SARS-CoV-2 infection had lower serum level of vitamin D (29.92 [22.22; 28.07] ng/ml) as compared with the control group (36.43 [32.05; 44.08] ng/ml; p<0.001). A total of 90% of the children with SARS-CoV-2 infection were diagnosed with insufficiency or deficiency of vitamin D (<30 ng/ml). Only 10 % of the patients had normal levels of vitamin D. The insufficiency of vitamin D was found more often amongst children aged 0-11 and deficiency of total 25-hydroxyvitamin D was more common for children aged 12-17. The difference in serum levels of vitamin D depending on the severity of SARS-CoV-2 infection was not found. Male children with SARS-CoV-2 infection showed lower levels of vitamin D (p=0.013). Conclusion. A total of 90 % of the children with SARS-CoV-2 infection had insufficiency or deficiency of vitamin D regardless of the severity of clinical symptoms.

scholarly journals The relationship between serum vitamin D level and COVID-19; a review study

2020 ◽  
Vol 5 (2) ◽  
pp. e34-e34
Author(s):  
Yasaman Koohshoori ◽  
Ehsan Ramanian ◽  
Nasrin Moradi ◽  
Shahrzad Shadabi ◽  
Minoo Motahhar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Length Of Hospital Stay ◽  
Hypovitaminosis D ◽  
Serum Levels ◽  
Potential Effect ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Relationship

Introduction: Coronavirus disease 2019 (COVID-19) from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the most important epidemiological events in the past 100 years has become, the consequences for public health and economic systems around the world. Vitamin D is an important micronutrient that has been reported to improve immunity and protect against respiratory diseases. In this study, we intend to review articles that examine the relationship between COVID-19 and vitamin D. Methods: This is a review that uses articles from studies published in 2020 on the relationship between COVID-19 and vitamin D in databases such as; Web of Science, Science Direct, SID, Magiran, Google Scholar and PubMed. Keywords used included; serum levels of 25-hydroxyvitamin D, vitamin D, COVID-19, SARS-COV-2 and coronavirus 2. With this search, 32 articles were finally selected for this purpose and their results were reviewed Results: Of the 32 studies reviewed, only three showed no association between vitamin D levels in the blood and COVID-19 disease. Other studies had a relationship between the severity of the disease, mortality rate and length of hospital stay, in different age, gender and location groups. Conclusion: It seems that the level of vitamin D in the blood has a potential effect on COVID-19 disease. Checking the serum vitamin D levels and supplementation in people with hypovitaminosis D can be a good solution to reduce the complications and problems caused by COVID-19.

scholarly journals Protective Effects of Aqueous and Hydroethanolic Extracts of Secamone afzelii (Asclepiadaceae) Leaves on Liver Transaminases, Serum Vitamin D and Zinc Levels against Carbon Tetrachloride (CCl4)- Induced Hepatotoxicity in Rats

2020 ◽  
pp. 1-9
Author(s):  
Koné Djoudori Serge ◽  
Gnahoue Goueh ◽  
Djyh Bernard Nazaire ◽  
Bamba Abou ◽  
Yapi Houphouet Félix
Keyword(s):  
Vitamin D ◽  
Carbon Tetrachloride ◽  
Serum Vitamin ◽  
Negative Control ◽  
Significant Rise ◽  
Protective Effects ◽  
Serum Vitamin D ◽  
Liver Transaminases ◽  
Zinc Levels ◽  
Hydroethanolic Extract

Purpose: This study was carried out to evaluate effect of aqueous and hydroethanolic extracts of Secamone afzelii leaves on Liver transaminases, serum vitamin D and Zinc levels in hepatotocixity induced by carbon tetrachloride (CCl4) in rats. Methods: The experiment was performed on 7 groups of 6 rats by the method of Mekky and collaborators. Rats were pre-treated with aqueous, hydroethanolic extracts Secamone afzelii (100 and 200 mg/kg) and Silymarin (SIL) an hepatoprotective reference prior to CCl4. Hepatotoxicity was induced by the intraperitoneal injection of Carbon tetrachloride (CCl4) in rats. Hepatotoxicity implied a significant rise of Liver transaminases (ALT and AST) by hepatocyte alteration rate. The parameters evaluated in the study were alanine aminotransferase (ALT), aspartate aminotransferase (AST), vitamin D and Zinc in serum. Vitamin D and Zinc levels in serum were respectively determined by HPLC analysis and Atomic absorption method. Results: Carbon tetrachloride injection to rats every 2 days showed a significant rise of Liver transaminases (ALT and AST) and a significant lowering of vitamin D and zinc levels in serum compared to normal. However, pre-treatments with aqueous and hydroethanolic extracts of Secamone afzelii caused a significant decrease of Liver transaminases (ALT and AST) and restored vitamin D and zinc levels in serum of animals (P < 0.001 and P < 0.01) compared to rats treated with CCl4 only (Negative control). Moreover, hydroethanolic extract (200 mg/kg) and Silymarin both reduced very well carbon tetrachloride effects by protecting Liver. Conclusion: This study reveals that Secamone afzelii leaves extracts (aqueous and hydroethanolic) possess protective properties of the Liver. It also shows a significant association between low serum vitamin D and zinc levels and hepatotoxicity. The most active extract is Hydroethanolic extract at the dose of 200 mg/kg which can be used for preventives purposes.

scholarly journals Vitamin D serum levels and peripheral arterial disease among southern Brazilian adults

2020 ◽  
Vol 66 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Simone Bonatto ◽  
Vera Maria Vieira Paniz ◽  
Clandio de Freitas Dutra ◽  
Ruth Liane Henn
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Peripheral Arterial Disease ◽  
Ankle Brachial Index ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Arterial Disease ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Peripheral Arterial

SUMMARY OBJECTIVE To investigate the association between low serum vitamin D levels and peripheral arterial disease (PAD). METHODS A cross-sectional study with a consecutive sample of 133 individuals from Caxias do Sul, Brasil. We considered PAD patients those with an ankle-brachial index (ABI) ≤ 0.90 or with arterial revascularization. Vitamin D serum level was categorized as sufficient (≥30 ng/mL), insufficient (>20 to 29 ng/mL), and deficient (<20 ng/mL). Prevalence ratios (RP) were calculated through Poisson regression. RESULTS The prevalence of PAD was 50.7% (95% CI 42-59). After adjustment for potential PAD risk factors, RP were 1.08 (95% CI 0.66-1.76) for insufficient serum level and 1.57 (95% CI 0.96-2.57) for deficient vitamin D serum level; (p for trend = 0.020). CONCLUSION Vitamin D serum levels showed an inverse and significant dose-response relationship with PAD.

scholarly journals Association of 25-hydroxyvitamin D, Cyclooxygenase-2 and Prostaglandin E2 Serum Levels in Breast Cancer Patients

2021 ◽  
Vol 13 (4) ◽  
pp. 426-32
Author(s):  
Theresia Ilyan ◽  
Dwi Retnoningrum ◽  
Meita Hendrianingtyas ◽  
Dian Widyaningrum ◽  
Banundari Rachmawati
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Serum Level ◽  
Prostaglandin E2 ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Cyclooxygenase 2 ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
25 Hydroxyvitamin D

BACKGROUND: Serum levels of 25-hydroxyvitamin D (25(OH)D), prostaglandin E2 (PGE2), and cyclooxygenase 2 (COX2) expression differ between breast cancer stages. Since, previous studies showed mixed results, in this study, we aimed to analyze vitamin D levels related to breast cancer stages and serum levels of COX2 and PGE2 in Indonesia.METHODS: This was a cross sectional study involving 75 breast cancer patients. Subjects were divided into 3 groups, namely operable early stage (K1), locally advanced stage (K2), and advanced stage (K3). Venous blood samples were taken from each subject, then were analyzed for the 25(OH)D, COX2, and PGE2 serum levels by enzyme-linked immunosorbent assay (ELISA) method.RESULTS: There were significant differences in 25(OH)D among groups (p=0.012); between K1 and K2 (p=0.009) and between K1 and K3 (p=0.023). However, there was no significant difference in serum COX2 level (p=0.328). There were significant differences of PGE2 among groups (p=0.002); between K1 and K2 (p=0.036) and between K1 and K3 (p=0.001). Correlation test showed that there were differences between 25(OH)D serum levels and PGE2 serum level (r=0.306, p=0.008) and also between 25(OH)D serum level and breast cancer stage (r=-0.229; p=0.048).CONCLUSION: There were differences in serum Vitamin D and PGE2 levels at various stages of breast cancer. Serum 25(OH)D levels had weak correlation with breast cancer stage and PGE2 serum level. Serum vitamin D level in advanced breast cancer were lower than early stage breast cancer and indicate a poor prognosis.KEYWORDS: breast cancer, 25-hydroxyvitamin D, cyclooxygenase 2, prostaglandin E2

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