scholarly journals Etude Phytochimique Et De Cytotoxicité De Quelques Plantes Utilisées Dans Le Traitement De La Stérilité Féminine Au Sud-Bénin

2018 ◽  
Vol 14 (6) ◽  
pp. 156
Author(s):  
Victorin Houmènou ◽  
Arlette Adjatin ◽  
Fidèle Assogba ◽  
Joachim Gbénou ◽  
Akpovi Akoègninou

The most cited plant drugs during an ethnobotanical survey conducted for traditional healers and resource persons in southern Benin, used in the treatment of female infertility, were the subject of a phytochemical screening. It aims to determine the chemical substances that are conferred on the plants. These chemical substances are the pharmacological properties that are used for the treat of ailment recognized as being the origin of this disease. As a result, we studied the cytotoxicity of each herbal drug. In total, the organs of 17 plant species involved in this study are Aframomum melegueta, Allium cepa, Anchomanes deformants, Baphia nitida, Carissa spinarum, Elaeis guineensis, Garcinia cola, Kigelia africana, Monodora myristica, Morinda lucida, Musa sapientum, Olax subscorpioidea, Piper guineense, Pterocarpus erinaceus, Pupalia lappacea, Tetrapleura tetraptera, Xylopia aethiopica. The results obtained indicate that the richness in phytochemical element is a function of the species. Thus, Aframomum melegueta, Garcinia kola, Monodora myristica, Tetrapleura tetraptera, Xylopia aethiopica, and Anchomanes difformis are rich in catechin and/or gallic tannins, mucilages, reducing compounds, anthocyanins and/or leucoanthocyanins. On the other hand, no drugs is at same time rich in free anthracenics, steroids and / or terpernoids, alkaloids, saponosides, and quinone derivatives. The calculated CL50 values for each of the plant organs are all greater than 0.1 mg / ml. None of them is toxic. However, the non-toxicity of an herbal drug does not mean the same with the multispecies recipe in which it is used. Pharmacological tests of the various recipes used are also of significant importance.

Author(s):  
Lydia M. Okorafor ◽  
Ishaq S. Eneji ◽  
Rufus Sha’Ato

Comparative study of the proximate and mineral components of five local spices (Denniettia tripetala, Monodora myristica, Piper guineense, Syzygium aromaticum, Xylopia aethiopica and) were investigated.  The proximate composition revealed that the spices had considerable carbohydrate ranging from 26.2 –  53.4%, crude fibre 13.6 – 23.7%, crude protein 5.67 – 10.9%, but low ash 2.41 – 5.56%, moisture 8.61 – 17.7%  and fat 2.34 – 24.3%; except D.tripetala  and M. myristica with high moisture content of 17.7%  and crude fat content of   24.3%, respectively.  The EDXRF analysis shows the presence of mineral elements in the order of K ˃ Ca ˃ Fe ˃ Zn ˃ Sr > Se ˃ Mo ˃ Cu ˃ Mn ˃ Br > Rb. Statistical analysis indicates that there is no significant difference (α = 0.01, 0.05) in the mean contribution of the various sample. However, there is a relationship between the constituents of P.guineense and S. aromaticum, X. aethopica, D. tripetala and the elements (Mn, Br) and (Se, Zn). Generally, the findings indicate that the five spices are good sources of nutrients and mineral elements which could be exploited as great potentials for drugs and/or nutritional supplements.


2021 ◽  
Vol 20 (2) ◽  
pp. 23-36
Author(s):  
J.S. Ashidi ◽  
O.O. Awokoya ◽  
A.S. Sanusi ◽  
R.T. Feyisola ◽  
O.C. Okechukwu ◽  
...  

Ethnobotanical survey of medicinal plants remains a veritable source of information leading to discovery of new lead compounds of pharmaceutical importance thus, the need for continual search for medicinal plants via ethnobotanical surveys in Nigeria. Structured questionnaires were administered amongst traditional healers. A few other anecdotal claims about efficacy of herbs from people who at one time or the other have used the plants for wound healing were also sampled. The result of an ethnobotanical survey of plants used in the treatment of wound in Ijebu North Local Government area of Ogun State and Ibadan North Local Government area of Oyo state of Nigeria are reported. A total of 71 species of plants covering 43 families were identified; representing 51 recipes. Carica papaya Linn, Elaeis guineensis Jacq, Chromolaena odorata Meull. Arg, Gladiolus psittacinus Hook.f., Vetivera kotschyana (Benth.) Stapf, Securidaca longipedunculata Fresen and Euphorbia laterifolia Linn were prominent among the recipes. Among all the families identified in the recipes, Euphorbiaceae was most mentioned (7.0%) followed by Compositeae, Fabacceae, Malvaceae and Meliaceae families (4.0%), Amaryllidaceae, Annonaceae, Arecaceae, Asphodeloideae, Asteraceae, Cucurbitaceae, Leguminosae, Musaceae, Poaceae, Rubiaceae, Rutaceae, Solanaceae, Sterculiaceae, Zingiberaceae followed closely (3.0%) while Acanthaceae, Amaranthaceae, Anacardiaceae and others had 1.0%. Out of the recipes, 51.9% are either leaves only or in combination with other parts, while 21.5% are stem bark, 7.6% are seeds and 3.8% are roots, bulbs and fruits respectively. These plants could be investigated for potential leads for wound healing in animal subjects.


Author(s):  
Adewale, Adetutu ◽  
Olusoji Abiodun, Owoade ◽  
Olanike Alabi ◽  
Fatima Aluko Abubakar ◽  
Olubunmi Simeon Oyekunle

Ethnopharmacological Relevance: Leukemia, a cancer of the blood and bone marrow is responsible for about 222.000 deaths annually. The side effects of chemotherapy in leukemia treatment have necessitated the search for natural products especially medicinal plants as alternative therapy. Aim: This study surveyed common plants used for treating leukemia in Oyo state, Nigeria and assessed the anti-leukemic and anti-clastogenic activities of fractions of Nymphaea lotus. Methods: Semi-structured questionnaire (1000) was used to collect the ethnobotanical data among the traditional healers. Leukemia was induced in albino mice with 400 mg/kg body weight of benzene intraperitoneally. Aqueous extracts (120mg/kg/bw), fractions and 5-florouracil (25mg) was administered to mice of different groups. The anti-leukemic, anti-clastogenic, antioxidant, hepatoprotective activities and hematological parameters were determined. N. lotus was subjected to gas-chromatography mass spectroscopy analysis. Results: The ethnobotanical survey recorded 89 plant species with their local names and parts used in the traditional therapeutic preparations. Seven plants (Pistiastratiotes (2.5%), Nymphaea lotus (1.4%), Piper guineense (1.7%), Securinega virosa (2.5%), Calotropis procera (3.4%), Morinda lucida (2.5%) and Xylopia aethiopica (4.5%) with the highest frequency of citation were selected for anti-leukemic and anti-clastogenic screening. The aqueous extract of N. lotus and M. lucida displayed anti-leukemic potential. M. lucida and X. aethiopica improved the hematological parameters. Ethyl acetate fraction of N. lotus significantly (p<0.05) reduced the number of micronucleated polychromatic erythrocyte in the bone marrow and showed anti-leukemic activity. Fractions of N. lotus restored the hematological parameters and exhibited significant (p<0.05) antioxidant activity. Histological observation revealed improvement in the liver general cyto-architecture of mice treated with ethyl acetate and butanol fractions of N. lotus. Some known compounds were identified in ethyl acetate fraction of N. lotus. Conclusion: Most of the species tested had some anti-leukemic effect in mice, which to some extent supports their traditional inclusion in herbal preparations for treatment of leukemia. The study also identified potential anti-leukemic compounds in N. lotus extract. The study also identified potential anti-leukemic compounds in N. lotus extract.


2020 ◽  
pp. 1-6
Author(s):  
Anumudu C K ◽  
◽  
Okolo C A ◽  
Ezembu E N ◽  
◽  
...  

This study demonstrates the antimicrobial activity of three spices, Piper guineense (Uziza), Xylopia aethiopica (Uda), Tetrapleura tetraptera (oshorisho) and their potential use as food biopreservatives. Essential oils of the spices seed were obtained and used in the agar-diffusion and tube dilution assays to determine their minimum inhibition (MIC) and bactericidal concentrations (MBC) against a common fruit juice spoilage organism (Bacillus cereus). MIC values of 50mg/ ml (Oshorisho) and 25mg/ml (Uziza and Uda) were obtained. Similarly, all spice extracts were bactericidal at a concentration of 100mg/ml. The spice extracts were utilized in the fortification of fresh fruit juice. Fortification of orange, pineapple and watermelon juices with extracts of the spices caused a reduction in the bacterial and fungi load of the juices over a period of 7 days in comparison to unpreserved controls. Orange juice preserved with uda had a fungal load of 1.9 x106 and bacterial load of 8.0 x106 compared to control with loads of 2.3 x107 and 1.1 x107 , respectively. Watermelon juice preserved with oshorisho had a fungal load of 1.2 x106 and bacterial load of 1.1 x107 compared to control with loads of 2.1 x107 and 8.8 x107 , respectively while pineapple juice preserved with uziza had a fungal load of 1.2 x107 and bacterial load of 1.6 x107 compared to control with loads of 2.7 x107 and 2.5 x108 , respectively. These results show that the spice extracts have potential for use as food preservatives for extending the shelf life of freshly prepared fruit juices. This is important as the demand for fresh foods free from chemical preservatives but microbiologically safe is on the increase.


Author(s):  
Koffi Akissi Jeanne ◽  
Tano Konan Dominique ◽  
Kangah Orphée Michelle Alerte ◽  
Rasmane Na Ahou Kaddy ◽  
Ehoulé Kroa ◽  
...  

Mosquitoes have developed resistance, hence the need for anti-malarial medicines. This resistance calls for therapeutic an interest to therapeutic alternatives, including the medicinal plants. An ethnopharmacological survey was conducted amongst 15 Traditional Healers, recommended by the National Program for the Promotion of Traditional Medicine using semi-structured interviews in the city of Bouna. The ethnobotanical survey conducted in 2019 has enabled the identification of 32 plant species belonging to 30 genera and grouped into 19 families. The most represented families were Fabaceae (5 species) Anacardiaceae (4 species), Annonaceae (3 species), Rubiaceae, Zingiberaceae, Asteraceae, and Combretaceae with 2 species each. The species were mostly trees (63.63%). Leaves were the most frequently used parts of the plants (44.4%). The results of our investigations show that the most used mode is the decoction (42.22%). The oral route (60%) is the most used mode of administration. These species complete the non-exhaustive list of medicinal plants that the populations of Cote d'Ivoire use. It was found out that, people in this area commonly use medicinal plants with trust they have built on the curative outcome witnessed. However, this creates a further work to test for the antiplasmodial activity and to develop of Traditional Improved Medicines (MTAs).


2010 ◽  
Vol 41 (No. 1) ◽  
pp. 14-20 ◽  
Author(s):  
M. Oparaeke A ◽  
C. Dike M ◽  
I. Amatobi C

The insecticidal efficacy of aqueous extracts of five Nigerian spices (Piper guineense Schum and Thonn., Aframomum melegueta (Roscoe), Xylopia aethiopica (Dunal) A. Rich., Zingiber officinale L. and Capsicum annuum L.) was tested in a field study for the control of two important post-flowering insect pests, Maruca vitrata Fab. (Lepidoptera: Pyralidae) and Clavigralla tomentosicollis Stal. (Hemiptera: Coreidae) of cowpea. The extracts were applied at 10% (w/v) and sprayed every week for 4 weeks. P. guineense, followed by A. melegueta, significantly reduced (P < 0.01) abundance of the pests and decreased the damage to cowpea pods. Grain yields were significantly higher in plots treated with P. guineense and A. melegueta extracts compared to plots treated with other extracts. This technology is cheap, safe, environmentally friendly and easy to adopt by limited resource farmers in third world countries.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Brice Armand Fanou ◽  
Jean Robert Klotoe ◽  
Lauris Fah ◽  
Victorien Dougnon ◽  
Charles Hornel Koudokpon ◽  
...  

Abstract Background Candidiasis, an opportunistic cosmopolitan disease is nowadays like bacterial infections which is a real public health problem. In view of the emergence of Candida strains resistant to existing antifungal agents, alternative solutions should be considered. This is the purpose of this ethnobotanical survey, which aims to identify the medicinal plant species traditionally used to treat candidiasis in traditional markets of southern Benin. Methods The study was performed from October 2015 to January 2018 in the traditional markets of Southern-Benin. Data were collected by two complementary methods: triplet purchase of medicinal recipes (ATRM) from herbalists markets and semi-structured interview (ISS) from traditional healers. Results A total of 109 species of medicinal plants belonging to 44 families have been listed and identified. The most frequently cited species were Pteleopsis suberosa Engl. & Diels, Lantana camara L., Cyanthillium cinereum (L.) H. Rob, Ocimum gratissimum L. and Lippia multiflora Moldenke with respectively 43.84, 39.73 and 34.25% citation frequencies for the last three species respectively. Leguminosae (20.18%), Euphorbiaceae (5.50%) and Apocynaceae (5.50%) were the most represented botanical families. Leafy stems were more used than other plant organs. The decoction and the oral route were the most appropriate methods of preparation and administration reported by traditional healers. Conclusion Benin’s plant cover is made up of a wide variety of medicinal plant species used in the traditionnal treatment of candidiasis and which may constitute new sources of medicines to be developed.


2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Mohammed Bourhia ◽  
Abdelaaty Abdelaziz Shahat ◽  
Omer Mohammed Almarfadi ◽  
Fahd Ali Naser ◽  
Wael Mostafa Abdelmageed ◽  
...  

Medicinal plants played an important role in traditional medicine for the treatment of diseases since antiquities. The aim of the study is to carry out an ethnobotanical survey on medicinal plants used traditionally in cancer treatment in the region of Greater Casablanca-Morocco, and to enhance the traditional herbal medicine knowledge. 110 traditional healers in the study area were interviewed face to face to response a survey questionnaire including the names of plants used in cancer treatment, used parts, methods of preparation, and route of administration. Indices of Fidelity Level (FL), Use Value (UV), and Relative Frequency of Citation (RFC) were calculated to identify the most effective plants used for cancer treatment. Eight species were specified including Aristolochia baetica, Aristolochia paucinervis, Bryonia dioica, Aquilaria malaccensis, Marrubium vulgare, Lavandula maroccana, Ephedra alata, and Euphorbia resinifera belonging to 7 families. Aristolochiaceae, Aquilariaceae, and Cucurbitaceae were the most useful families in cancer treatment with high significant indices of UV, FL, and RFC with values of 1, 100%, and 1, respectively. Roots and leaves were the most commonly used plant parts. Decoction and powder mixed with honey were the frequently used method for remedies preparation. The present study showed that the people living in Morocco’s economic capital are still highly dependent on traditional herbal medicine for the treatment of cancer. Therefore, it seems that herbal medicine still plays a crucial role in the primary healthcare system for the local population. During this survey, it was reported that even some plant families are highly toxic for humans like Aristolochiaceae that are frequently used in cancer treatment in the study area. As many people still rely on natural traditional medicine considering (it is safe with no side effects), so combined effort between all social categories including scientists and traditional healers should be established for involving the scientific validity of the used plants in the treatment of diseases.


2020 ◽  
Vol 2020 ◽  
pp. 1-18
Author(s):  
Gundo Mudau ◽  
Samuel Odeyemi ◽  
John Dewar

Hypertension is a dominant risk factor for the development of cardiovascular, kidney, and eye diseases. In Africa, it increasingly leads to hospitalisation and a strain on the public health system. However, rather than modern medicine, African traditional healers are the first choice for most South Africans. Therefore, this study is aimed at gathering information on herbal remedies traditionally used for the treatment of high blood pressure in Vhavenda, South Africa, and comparing this information with reports in the literature regarding plants used to manage high blood pressure. An ethnobotanical survey was carried out in Vhembe district and its environs with 53 herbalists and indigenous people aged between 36 and 66 years from January to October 2019 using a semistructured questionnaire. The plants were collected with each respondent; they were authenticated and kept in herbarium. A total of 51 different plants were mentioned as being most commonly used for hypertension treatment. Of these, 44 plants were identified, with those from the Fabaceae family followed by plants from the Celastraceae family being commonly mentioned. Of these, the Elaeodendron transvaalense, Tabernaemontana elegans, Elephantorrhiza elephantina, and Aloe vossii were commonly cited species. According to the literature data, most of the identified plants are yet to be scientifically investigated for the treatment of hypertension, whereas only preliminary investigations have been carried out on other plants, suggesting that these preliminary investigations may have highlight promising antihypertensive activities in vitro that are indicative of their potential as antihypertensive drugs. Therefore, there is a need to scientifically investigate the antihypertensive potentials of these plants as a potential source of antihypertensive treatment and compounds.


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