White Tea (Camellia Sinensis (L.)): Antioxidant Properties And Beneficial Health Effects

The edible parts of the plants Camellia sinensis, Vitis vinifera and Withania somnifera were extensively used in ancient practices such as Ayurveda, owing to their potent biomedical significance. They are very rich in secondary metabolites such as polyphenols, which are very good antioxidants and exhibit anti-carcinogenic properties. This study aims to evaluate the anti-cancerous properties of these plant crude extracts on human liver cancer HepG2 cells. The leaves of Camellia sinensis, Withania somnifera and the seeds of Vitis vinifera were collected and methanolic extracts were prepared. Then, these extracts were subjected to DPPH, α- amylase assays to determine the antioxidant properties. A MTT assay was performed to investigate the viability of the extracts of HepG2 cells, and the mode of cell death was detected by Ao/EtBr staining and flow cytometry with PI Annexin- V FITC dual staining. Then, the protein expression of BAX and BCl2 was studied using fluorescent dye to determine the regulation of the BAX and BCl2 genes. We observed that all the three extracts showed the presence of bioactive compounds such as polyphenols or phytochemicals. The W. somnifera bioactive compounds were found to have the highest anti-proliferative activity on human liver cancer cells.

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Antioxidant and Chemopreventive Effect of Aliophen® Formulation Based on Malts and Hops

Antioxidants ◽

10.3390/antiox10010029 ◽

2020 ◽

Vol 10 (1) ◽

pp. 29

Author(s):

Idolo Tedesco ◽

Carmela Spagnuolo ◽

Stefania Bilotto ◽

Angelo A. Izzo ◽

Francesca Borrelli ◽

...

Keyword(s):

Health Effects ◽

Low Density Lipoprotein ◽

Antioxidant Properties ◽

Density Lipoprotein ◽

Ldl Oxidation ◽

Preneoplastic Lesions ◽

Chemically Induced ◽

Chemopreventive Effect ◽

The One ◽

Higher Doses

Experimental and clinical studies evidenced the health effects of moderate consumption of beer, mainly due to the presence of bioactive compounds, such as polyphenols, vitamins, or fibers. To exploit the potential beneficial effect on health and in disease prevention of these compounds, a new beverage based on barley malts and hops named Aliophen® has been designed, through a patented production process, with a high total polyphenolic amount compared to alcohol-free beer and similar to the one present in light and dark beers. In the present study, the antioxidant activity of Aliophen® against low-density lipoprotein (LDL) oxidation and its ability to protect erythrocytes from hemolysis have been characterized. Moreover, the chemopreventive effect of Aliophen® against colon cancer has been assessed, employing a mouse model of chemically induced carcinogenesis using azoxymethane (AOM). Data obtained showed that Aliophen at a low dose (3 mg/kg) inhibited the formation of preneoplastic lesions, polyps, and tumors. At higher doses (300 mg/kg) the protective effect was measured in the first phase of the onset of cancer. The antioxidant properties of Aliophen® were also observed in AOM-treated mice where it increased the serum antioxidant capacity. Based on the data presented, Aliophen® can exert promising health effects, including an anticancer capacity presumably associated with its antioxidant properties.

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Practical mediated-assembly synthesis of silver nanowires using commercial Camellia sinensis extracts and their antibacterial properties

New Journal of Chemistry ◽

10.1039/c7nj03812g ◽

2018 ◽

Vol 42 (3) ◽

pp. 2133-2139 ◽

Cited By ~ 13

Author(s):

M. Flores-González ◽

M. Talavera-Rojas ◽

E. Soriano-Vargas ◽

V. Rodríguez-González

Keyword(s):

Phenolic Compound ◽

Camellia Sinensis ◽

Silver Nanowires ◽

Antioxidant Properties ◽

Antibacterial Properties

Camellia sinensis is a well-known plant used for health purposes due to its high phenolic compound content and antioxidant properties.

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White tea (Camellia sinensis) extract reduces oxidative stress and triacylglycerols in obese mice

Food Science and Technology ◽

10.1590/s0101-20612012005000099 ◽

2012 ◽

Vol 32 (4) ◽

pp. 733-741 ◽

Cited By ~ 7

Author(s):

Lílian Gonçalves Teixeira ◽

Priscilla Ceci Lages ◽

Tatianna Lemos Jascolka ◽

Edenil Costa Aguilar ◽

Fabíola Lacerda Pires Soares ◽

...

Keyword(s):

Oxidative Stress ◽

Body Weight ◽

Adipose Tissue ◽

Camellia Sinensis ◽

Reduce Food Intake ◽

Obese Mice ◽

White Tea ◽

Diet Induced Obesity ◽

Tea Extract ◽

The Relationship

White tea is an unfermented tea made from young shoots of Camellia sinensis protected from sunlight to avoid polyphenol degradation. Although its levels of catechins are higher than those of green tea (derived from the same plant), there are no studies addressing the relationship between this tea and obesity associated with oxidative stress.The objective of this study was to evaluate the effect of white tea on obesity and its complications using a diet induced obesity model. Forty male C57BL/6 mice were fed a high-fat diet to induce obesity (Obese group) or the same diet supplemented with 0.5% white tea extract (Obese + WTE) for 8 weeks. Adipose tissue, serum lipid profile, and oxidative stress were studied. White tea supplementation was not able to reduce food intake, body weight, or visceral adiposity. Similarly, there were no changes in cholesterol rich lipoprotein profile between the groups. A reduction in blood triacylglycerols associated with increased cecal lipids was observed in the group fed the diet supplemented with white tea. White tea supplementation also reduced oxidative stress in liver and adipose tissue. In conclusion, white tea extract supplementation (0.5%) does not influence body weight or adiposity in obese mice. Its benefits are restricted to the reduction in oxidative stress associated with obesity and improvement of hypertriacylglycerolemia.

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White tea drink (Camellia sinensis) improves endurance and body weight maintenance of rats

Journal of Health Research ◽

10.1108/jhr-01-2020-0020 ◽

2020 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Mahmud Aditya Rifqi ◽

Stefania Widya Setyaningtyas ◽

Qonita Rachmah

Keyword(s):

Body Weight ◽

Weight Gain ◽

Beneficial Effect ◽

Camellia Sinensis ◽

Intervention Research ◽

The Body ◽

Human Intervention ◽

Content Type ◽

White Tea ◽

Significant Difference

PurposeWhite tea is an unfermented tea made from young shoots of Camellia sinensis protected from sunlight to avoid polyphenol degradation. White tea contains a high level of polyphenolic compounds known as catechins. Several types of evidence have suggested that tea consumption has benefits in body weight and endurance maintenance. This study was designed to evaluate the effect of white tea on body weight and endurance of animal models.Design/methodology/approachThis research was an intervention design using 20 Wistar white rats (Rattus Norvegicus) in body weight between 150 and 200 g. The rats were randomized into four groups, three groups receiving white tea drink (WTD) with different doses and the other group receiving plain water in equal volume as a control group for four weeks. The forced swim test (FST) was done to measure their struggling capacity, and digital bodyweight to measure the weight.FindingsIntervention (WTD Groups and Control) caused weight gain among except G3 with the highest doses of white tea. The result showed that WTD intake in G3 had a significant difference (p < 0.05) on body weight gain compared to control. The authors found that WTD in a specific dose (G3: 0.22 mg) tends to maintain the body weight of animals (219.2 ± 41.96; 212.6 ± 46.90, respectively), while other doses caused weight gain. WTD also significantly increased the swimming and struggling capacity of rats that represented improvements the endurance along with the test. There was a statistically significant difference in endurance among all groups (p < 0.05).Research limitations/implicationsThe results of this study can be followed as human intervention research as an input for nutritionists and sports scientists to explore the beneficial effect of white tea.Practical implicationsThe results of this study can be followed as human intervention research as an input for nutritionists and sports scientists to explore the beneficial effect of white tea.Originality/valueThis study adds more evidence and information about the advantages of white tea as potential beverages in future healthy lifestyles.

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The Free Radical Scavenging and Anti-Isolated Human LDL Oxidation Activities of Pluchea indica (L.) Less. Tea Compared to Green Tea (Camellia sinensis)

BioMed Research International ◽

10.1155/2020/4183643 ◽

2020 ◽

Vol 2020 ◽

pp. 1-12

Author(s):

Kittipot Sirichaiwetchakoon ◽

Gordon Matthew Lowe ◽

Griangsak Eumkeb

Keyword(s):

Free Radical ◽

Green Tea ◽

Camellia Sinensis ◽

Hypochlorous Acid ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Free Radical Scavenging ◽

Ldl Oxidation ◽

Caffeoylquinic Acid ◽

Dicaffeoylquinic Acid

Tea is one of the most popular beverages in the world. Camellia sinensis tea (CST) or green tea is widely regarded as a potent antioxidant. In Thailand, Pluchea indica (L.) Less. tea (PIT) has been commercially available as a health-promoting drink. This study focused on free radical scavenging activities of PIT, and its ability to protect isolated human low-density lipoproteins (LDL) from oxidation by chemical agents. A preliminary study to investigate the antioxidant nature of PIT was undertaken. These included common antioxidant assays involving 2,2-Diphenyl-1-picrylhydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS), hypochlorous acid (HOCl), and its potential to scavenge peroxynitrite. In separated experiments, isolated human LDL was challenged with either 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH), copper (Cu2+), or 3-Morpholinosydnonimine hydrochloride (SIN-1) to induce LDL oxidation. PIT exhibited antioxidant activity in all test systems and performed significantly better than CST in both DPPH (P<0.05; IC50PIT=245.85±15.83 and CST=315.41±24.18 μg/ml) and peroxynitrite scavenging assays. PIT at 75 μg/ml almost fully prevented the peroxynitrite over a 5 h period. Moreover, it displayed similar properties to CST during the antioxidation of isolated human LDL using AAPH, Cu2+, SIN-1, and hypochlorous acid scavenging assays. However, it revealed a significantly lower ABTS scavenging activity than CST (P<0.05; IC50PIT=30.47±2.20 and CST=21.59±0.67 μg/ml). The main constituents of the PIT were identified using LC-MS/MS. It contained 4-O-caffeoylquinic acid (4-CQ), 5-O-caffeoylquinic acid (5-CQ), 3,4-O-dicaffeoylquinic acid (3,4-CQ), 3,5-O-dicaffeoylquinic acid (3,5-CQ), and 4,5-O-dicaffeoylquinic acid (4,5-CQ). In conclusion, caffeoyl derivatives in PIT could play an important role in potent antioxidant properties. So, it may be further developed to be antioxidant beverages for preventing atherosclerosis and cardiovascular diseases associated with oxidative stress.

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