scholarly journals Autres orbivirus : Mise à jour des informations sur la peste équine africaine et la maladie hémorragique épizootique en Europe et dans le bassin méditerranéen

2009 ◽  
Vol 62 (2-4) ◽  
pp. 92
Author(s):  
M. Martinez ◽  
B. Rodriguez ◽  
J. M. Sanchez-Vizcaino
Keyword(s):  
Animal Health ◽  
Diagnostic Techniques ◽  
Social Consequences ◽  
Control Measures ◽  
Effective Vaccine ◽  
African Countries ◽  
Bassin Méditerranéen ◽  
Haemorrhagic Disease ◽  
Educational Campaigns ◽  
And Control

Orbiviruses are vector-borne pathogens that can cause notifi­able diseases in animals, such as bluetongue (BT) and epizootic haemorrhagic disease of deer (EHD) in ruminants, or African horse sickness (AHS) in equines. The relatively recent expansion of BT in Europe to higher latitudes than expected has evidenced the need to explore the ways of introduction and exposure of other orbiviruses in Europe and in the Mediterranean Basin. AHS was successfully eradicated from Europe since the 1990s but continues to be endemic in many African countries. Of the nine AHS serotypes, two have been present in Mediterranean coun­tries: AHS-9 (1966) and AHS-4 (1987-1990). The last outbreaks (up to 2008) of AHS in Africa classified by serotype occurred in Senegal (AHS-9), Kenya (AHS-4), and Nigeria, Senegal and Ethiopia (AHS-2). EHD is caused by 10 serotypes and is notifi­able to the World Organisation for Animal Health (OIE) since 2008. It is present in America, Australia, Asia and Africa and is known to affect wild ruminants as well as cattle. EHD has been present in cattle in North Africa (EHD-9) and the Middle East (EHD-7) since 2006. Transport of infected Culicoides from Northern Africa to Southern Europe by wind is a proved way of orbivirus introduction. Import of infected asymptomatic animals from an endemic country also happened the first time AHS was introduced in Spain. Then, certain environmental conditions such as warm temperatures can favour perpetuation of the dis­ease in animals exposed to infected vectors. The frequent con­sideration of horses as expensive leisure animals can worsen the economic and social consequences of a possible outbreak. However, nowadays there are good diagnostic techniques for AHS. Eradication can be achieved with the available polyvalent live vaccines and control measures. This is not the case for EHD, because an effective vaccine is urgently needed and there have been cross-reactions in the diagnoses between BT and EHD. European countries can prepare against other orbivirus outbreaks by prevention through educational campaigns and inactivated vaccine banks for AHS, and by further research on the possible vectors, the overwintering capacity of certain orbiviruses, the infectivity in all affected species, the identification of other pos­sible reservoirs, and the development of risk assessments and modelling.

scholarly journals Predicted UV-C Sensitivity of Human and Non-human Vertebrate (+) ssRNA Viruses

2021 ◽  
Author(s):  
Brahmaiah Pendyala ◽  
Ankit Patras
Keyword(s):  
Animal Health ◽  
Control Measures ◽  
Infection Prevention And Control ◽  
Infectious Bronchitis ◽  
Ssrna Virus ◽  
Pathogenic Viruses ◽  
Predicted Values ◽  
Prevention And Control Measures ◽  
And Control ◽  
Uv C

Epidemic and pandemic infectious diseases caused by RNA viruses constitute a significant hazard to human and animal health. Disinfection is an essential aspect of infection prevention and control measures. In this study, we estimated UV-C sensitivity of 83 human and veterinary pathogenic (+) ssRNA viruses by developed pyrimidine dinucleotide frequency-based genomic model. The data showed that the avian infectious bronchitis virus (genus: γ-coronavirus) with an estimated D90 value of 17.8 J/m2 was highly UV sensitive, whereas Salivirus NG-J1 (genus: salivirus) with a D90 value of 346.4 J/m2 was highly UV resistant. Overall, the trend of UV-C sensitivity of (+) ssRNA virus families followed as Coronaviridae < Flaviviridae < Togadoviridae < Arteriviridae, Matonaviridae, Astroviridae < Caciviridae < Picornaviridae < Nodaviridae < Herpeviridae. The results revealed that the enveloped viral families (Coronaviridae, Flaviviridae, Togadoviridae Arteriviridae, and Matonaviridae) are more UV-C sensitive than other non-enveloped families. Further validation of the model estimated UV sensitivity with literature available experimental data showed good agreement of predicted values. The estimates presented here could make it possible to reasonably predict UV-C disinfection efficiency of human and veterinary pathogenic viruses, which need specific biosafety requirements and/or difficult to cultivate in lab conditions.

scholarly journals African swine fever virus – the possible role of flies and other insects in virus transmission

2020 ◽  
Vol 64 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Mateusz Fila ◽  
Grzegorz Woźniakowski
Keyword(s):  
African Swine Fever Virus ◽  
Animal Health ◽  
Virus Transmission ◽  
Disease Outbreaks ◽  
African Swine Fever ◽  
Disease Spread ◽  
The Baltic ◽  
Haemorrhagic Disease ◽  
And Control

AbstractAfrican swine fever (ASF) is an acute viral haemorrhagic disease of pigs and wild boars. It presents a serious threat to pig production worldwide, and since 2007, ASF outbreaks have been recorded in the Caucasus, Eastern Europe, and the Baltic States. In 2014, the disease was detected in Poland. ASF is on the list of notifiable diseases of the World Organisation for Animal Health (OIE). Due to the lack of an available vaccine and treatment, the countermeasures against the disease consist in early detection of the virus in the pig population and control of its spread through the elimination of herds affected by disease outbreaks. Knowledge of the potential vectors of the virus and its persistence in the environment is crucial to prevent further disease spread and to understand the new epidemiology for how it compares to the previous experience in Spain gathered in the 1970s and 1980s.

scholarly journals Potential contribution of climate conditions on COVID-19 pandemic transmission over West and North African countries

2021 ◽  
Author(s):  
Ibrahima Diouf ◽  
Souleymane Sy ◽  
Habib Senghor ◽  
Papa Fall ◽  
Diarra Diouf ◽  
...  
Keyword(s):  
Control Measures ◽  
Specific Humidity ◽  
World Health ◽  
Potential Contribution ◽  
Gulf Of Guinea ◽  
The European Union ◽  
African Countries ◽  
Climate Conditions ◽  
The World ◽  
And Control

AbstractThe COVID-19 disease, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is a very contagious disease that has killed many people around the world. According to the World Health Organization (WHO) data, the spread of the disease appears to be slower in Africa. Although a number of studies have been published on the relationship between meteorological parameters and COVID-19 transmission, the effects of climate conditions on COVID-19 remain largely unexplored and without consensus following the main research finding over Africa (often based on a single country or city). Here, using available epidemiological data over 275 days (i.e., from March 1 to November 30, 2020) taken from the European Center for Disease Prevention and Control of the European Union database and daily data of surface air temperature and humidity from the National Center for Environmental Prediction (NCEP), this paper investigates the potential contributions of climate conditions on COVID-19 transmission over 16 countries selected from three bioclimatic regions of Africa (i.e., Sahel, Maghreb and Gulf of Guinea). On average, our main findings highlight statistically significant inverse correlations between COVID-19 cases and temperature over the Maghreb and the Gulf of Guinea regions, whereas positive correlations are found in the Sahel, especially over the central part including Niger and Mali. Correlations with specific humidity and water vapor parameters display significant and positive values over the Sahelian and the Gulf of Guinean countries and negative values over the Maghreb countries. In other word, results imply that the COVID-19 pandemic transmission is influenced differently across the three bioclimatic regions: i) cold and dry environmental conditions over the Maghreb; ii) warm and humid conditions over the Sahel iii) cold and humid conditions over the Gulf of Guinea. These findings could be useful for decision-makers who plan public health and control measures in affected African countries and would have substantial implications for directing respiratory disease surveillance activities.

Salmonella spp. in pigs: an update on diagnostics and control

Livestock ◽  
2020 ◽  
Vol 25 (1) ◽  
pp. 38-43
Author(s):  
Christina Gale ◽  
Eduardo Velazquez
Keyword(s):  
Animal Health ◽  
Clinical Signs ◽  
Diagnostic Techniques ◽  
Antimicrobial Treatment ◽  
Diagnostics And Control ◽  
Salmonella Spp ◽  
Pig Farms ◽  
And Control ◽  
On Farm

Salmonella spp. is an important topic for both human and animal health, particularly Salmonella enterica ser. Typhimurium including its monophasic strains. Salmonella is an increasing problem on pig farms and the bacteria are transmitted through breeding pyramids, and can spread rapidly due to the high number of subclinical cases. Therefore, diagnosis on farm is extremely important, ensuring sampling from all areas of the unit to gain the overall infection picture. Modern diagnostic techniques allow differentiation between field and vaccine strains which is extremely important when implementing a vaccination programme on the farm. Vaccination accompanied by hygiene and biosecurity measures make up the three pillars of Salmonella spp. control, each of which should be given equal attention. Vaccination has been shown to be very effective in reducing environmental pressure and therefore prevalence and clinical signs due to S. enterica ser. Typhimurium. Vaccination forms part of successful Salmonella spp. control, although it is important to remember that Salmonella spp. control requires a long-term approach using a combination of interventions and avoiding the long-term use of antimicrobial treatment.

scholarly journals Molecular characterization of ochratoxin A-producing fungi isolated from poultry feed

2019 ◽  
Vol 3 (1) ◽  
pp. 15-27
Author(s):  
Youssuf A. Gherbawy ◽  
Eman G.A. El-Dawy ◽  
Hams M.A. Mohamed
Keyword(s):  
Ochratoxin A ◽  
Phylogenetic Analyses ◽  
Animal Health ◽  
Health And Safety ◽  
Toxin Production ◽  
Control Measures ◽  
Poultry Feed ◽  
Aspergillus Section Nigri ◽  
And Control ◽  
Aspergillus Section

Mycotoxins are toxic metabolites mainly produced by Aspergillus spp. fungi. Further fungal characterization and mycotoxin estimation in feed are crucial measures for animal health and safety. The aim of this study was to identify and characterize mycotoxin-producing fungi in poultry feed. Forty poultry ration samples were collected and were subjected to morphological and molecular as well as to phylogenetic analyses of Aspergillus section Nigri. On average, 40% (16 of 40 samples) were contaminated with Aspergillus section Nigri fungi. Moreover, A. niger and A. tubingensis were identified and characterized in the contaminated poultry feed using molecular and phylogenetic analyses. Furthermore, our results showed that ochratoxin A was produced by some fungal isolates indicating their mycotoxigenicity.  In conclusion, A. niger and A. tubingensis contaminate poultry feed and can produce mycotoxins under optimal conditions. Furthermore, several preventive and control measures should be undertaken to reduce the occurrence of fungal contamination and toxin production in poultry rations.

scholarly journals Prevention and control of bovine cysticercosis: a Delphi study

2016 ◽  
Vol 37 (6) ◽  
pp. 4139 ◽  
Author(s):  
Elizandro Pruence Nickele ◽  
Maria Assunta Busato
Keyword(s):  
Health Education ◽  
Delphi Study ◽  
Prevention And Control ◽  
Animal Health ◽  
Parasitic Infection ◽  
Integrated Approach ◽  
Control Measures ◽  
The Third ◽  
Bovine Cysticercosis ◽  
And Control

Bovine cysticercosis is a zoonotic parasitic infection caused by the larval stage (Cysticercus bovis) of Taenia saginata. This study aimed to identify prevention and control measures for bovine cysticercosis indicated by experts in the fields of public and animal health. The study was conducted through three rounds of the Delphi method and had the participation of 44 experts from 13 Brazilian states in 30 educational institutions, research institutions, and sanitary inspection services. The first round comprised an open question, the answers to which formed the basis for structuring the second and third questionnaire. To reach a consensus in the second and third rounds, experts were asked to express their agreement or disagreement of each proposition on the questionnaire using a five-point Likert scale. A descriptive statistical analysis was performed at the end of each round. Twenty-three specialists (52.27%) participated in all three rounds. The first round resulted in 28 proposals categorized into six areas: health education, methods of diagnosis and treatment, sanitation measures, epidemiological studies, legislation and sanitary supervision, and intersectorality. In the second round, the experts reached a consensus on 16 propositions (57.14%). This percentage increased by 3.54% during the third round. At the end of the third round, the experts had reached a consensus on 17 of the 28 initial propositions (60.71%). The highest percentage of agreement (29.4%) was observed in the category of health education. This study allowed us to identify 17 recommendations pertaining to the prevention and control of bovine cysticercosis. These measures are not mutually exclusive, and require an integrated approach to the establishment of intervention actions at various points in the life cycle of the parasite.

scholarly journals VACCINATION AGAINST MALARIA: REALITY AND PERSPECTIVES

2017 ◽  
Vol 22 (3) ◽  
pp. 153-156
Author(s):  
S. K Litvinov ◽  
A. M Bronshteyn ◽  
E. N Morozov
Keyword(s):  
Malaria Control ◽  
Public Health Problem ◽  
Control Measures ◽  
World Health ◽  
European Medicines Agency ◽  
Morbidity Rate ◽  
Effective Vaccine ◽  
Protein Vaccine ◽  
Insecticide Treated Nets ◽  
African Countries

Malaria continues to be a major international public health problem. However a significant reduction in the morbidity rate has been achieved over the past decade. The effective vaccine against malaria, caused by P. falciparun, could contribute significantly to the prevention and control of the disease, as tropical malaria is most widely distributed in the world. Nowadays there is the only RTS,S/AS01 vaccine had passed the accomplished phase 3 of clinical trial and received endorsement of certain bodies of World Health Organization and European Medicines Agency. RTS,S/AS01 is a pre-erythrocytic hybrid recombinant protein vaccine. Both immunogenicity and effectiveness of this vaccine particularly in children aged of 5-12 months were demonstrated by the trial at the time for first vaccination. Vaccine should be administered 3 times as the initial series of inoculation with 4 weeks interval and then the 4th dose should be given 15-18 months later. Since there is still a number of issues required certain clarifications, the decision has been taken to undertake another relatively large pilot project in African countries, prior to final recommendations on the vaccine use could be developed and proposed to countries. The implementation of this new trial will definitely take appropriate time. The contribution of vaccine to malaria control might be significant only if used simultaneously with other proved malaria control measures, such as the use of insecticide-treated nets, detection of malaria cases with the use of rapid diagnostic tests and subsequent its treatment, chemoprevention when appropriate and, of course vector control. The consideration of the vaccine use as the mechanism, which should allow achieve the eradication of the disease is not appropriate in principle.

scholarly journals Rabies mortality and morbidity associated with animal bites in Africa: A case for Integrated Rabies Diseases Surveillance, Prevention and Control - A Scoping review

2020 ◽  
Author(s):  
Peter Nyasulu ◽  
Jacqueline Weyer ◽  
Rea Tschopp ◽  
Adane Mihret ◽  
Abraham Aseffa ◽  
...  
Keyword(s):  
Rural Areas ◽  
Prevention And Control ◽  
Animal Health ◽  
Global Strategy ◽  
World Health ◽  
Human Rabies ◽  
Post Exposure Prophylaxis ◽  
African Countries ◽  
Rabies Control ◽  
And Control

Background: Rabies a neglected tropical disease, mostly affecting poor and vulnerable populations living in remote rural areas in developing countries. The disease continues to pose a significant public health a threat with an estimated 59,000 dog-transmitted human deaths, of which an estimated 21,476 human deaths occur in Africa each year. The global strategy has been set by the quartite World Health Organization (WHO), the World Organization for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and the Global Alliance for Rabies Control (GARC), aiming for "zero human deaths associated with dog transmitted rabies by 2030". African countries, however, face several challenges and there are still gaps in controlling rabies. The aim of this study review is to determine rabies prevalence, mortality and associated risk factors in both human population and animal population and to evaluate the presence or absence of integrated one health surveillance response in African nations. Methods and analysis: We will conduct an electronic literature searches on PubMed, CINAHL, (Cumulative Index of Nursing and Allied Health Literature), Scopus, and Web of Science and other relevant databases. Reference lists from identified published articles or reviews and conference abstracts will also be searched for relevant articles. Published and unpublished literatures (grey) will be included in the search. The findings will be presented graphically in terms of mortality, morbidity, interventions for rabies control in Africa, research gaps identified, available research evidence, rabies surveillance, prevention and control and adverse events. Conclusion: This review will contribute to the coordination of interventions for surveillance, prevention, and control with African countries as country-based gaps and challenges and opportunities will be highlighted. In addition, the scaling up of post-exposure prophylaxis (PEP rabies will be evaluated in African countries and the projection to achieve the target of "zero deaths of human rabies by 2030" in Africa.

scholarly journals COVID-19: Risks of Re-emergence, Re-infection, and Control Measures -- A Long Term Modelling Study

2020 ◽  
Author(s):  
Subhas Kumar Ghosh ◽  
Sachchit Ghosh
Keyword(s):  
Control Measures ◽  
Effective Vaccine ◽  
Acquired Immunity ◽  
Model Parameters ◽  
Contact Rate ◽  
Spread Of Infection ◽  
And Control ◽  
Current Stage ◽  
Potential Peak

In this work we define a modified SEIR model that accounts for the spread of infection during the latent period, infections from asymptomatic or pauci-symptomatic infected individuals, potential loss of acquired immunity, people's increasing awareness of social distancing and the use of vaccination as well as non-pharmaceutical interventions like social confinement. We estimate model parameters in three different scenarios - in Italy, where there is a growing number of cases and re-emergence of the epidemic, in India, where there are significant number of cases post confinement period and in Victoria, Australia where a re-emergence has been controlled with severe social confinement program. Our result shows the benefit of long-term confinement of 50% or above population and extensive testing. With respect to loss of acquired immunity, our model suggests higher impact for Italy. We also show that a reasonably effective vaccine with mass vaccination program can be successful in significantly controlling the size of infected population. We show that for India, a reduction in contact rate by 50% compared to a reduction of 10% in the current stage can reduce death from 0.0268% to 0.0141% of population. Similarly, for Italy we show that reducing contact rate by half can reduce a potential peak infection of 15% population to less than 1.5% of population, and potential deaths from 0.48% to 0.04%. With respect to vaccination, we show that even a 75% efficient vaccine administered to 50% population can reduce the peak number of infected populations by nearly 50% in Italy. Similarly, for India, a 0.056% of population would die without vaccination, while 93.75% efficient vaccine given to 30% population would bring this down to 0.036% of population, and 93.75% efficient vaccine given to 70% population would bring this down to 0.034%.

scholarly journals Latest trends in L. infantum infection in dogs in Spain (Part II): current clinical management and control according to a national survey in practitioners

2020 ◽  
Author(s):  
Ana Montoya ◽  
Rosa Gálvez ◽  
Rocio Checa ◽  
Juliana Sarquis ◽  
Alexandra Plaza ◽  
...  
Keyword(s):  
Clinical Management ◽  
Complete Blood Count ◽  
Clinical Signs ◽  
Diagnostic Techniques ◽  
Control Measures ◽  
Canine Leishmaniosis ◽  
Cutaneous Lesions ◽  
Treatment Protocols ◽  
And Control ◽  
Monitoring Treatment

Abstract Background Canine leishmaniosis (CanL) is a parasitic zoonotic disease, endemic in the Mediterranean basin including Spain. While knowledge about CanL, its management, treatment, prevention and control mounts, it remains unclear whether all clinical veterinarians follow the same international recommendations, such as those of the LeishVet group. This study was thus designed to assess recent trends in the clinical management of CanL in veterinary clinics across Spain through a questionnaire-based survey. Results were compared with those of our prior national multicenter questionnaire administered by our research team in 2005. Methods A questionnaire consisting of 28 questions about CanL was developed using Google Forms and distributed by email to 1428 veterinary clinics in Spain. Questions were designed to obtain data on common clinical signs, techniques and complementary exams used to diagnose the disease, and on its monitoring, treatment and control measures. Data were collected in a database for statistical analysis. Results Completed questionnaires were returned by 295 clinics. Compared to the situation in 2005, replies indicate that clinical signs of CanL have not changed significantly, cutaneous lesions being still the most prevalent sign observed by practitioners. Quantitative serological techniques are considered an adequate approach to diagnosis, provided their results are supported by the findings of a thorough physical exam, as well as complementary tests (complete blood count (CBC), biochemical profile, plasma protein electrophoretogram and complete urinalysis). Treatment protocols and check-ups follow international recommendations. Finally, a multimodal approach is being endorsed to adequately control CanL including preventive measures such as: annual serological check-ups and the combination of repellents and vaccines. Besides, owners are being better informed about CanL by veterinarians, which translates to the improved control of this zoonosis. Conclusions The clinical management of CanL has recently undergone significant changes owing to improvements in clinical knowledge of the disease, more unified international criteria, improved diagnostic techniques and their adequate interpretation, as well as a greater awareness of the disease transmitted to owners.

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