scholarly journals Estimación de la tasa de filtración glomerular en personas con y sin síndrome metabólico

2016 ◽  
Vol 3 (1) ◽  
pp. 22
Author(s):  
María E Lizardo ◽  
María del Pilar Navarro ◽  
Marqjuly Camacho ◽  
Melvimar Alejandra Magallanes-Hernández ◽  
Rubsy Gabriela Pacheco-Gutiérrez ◽  
...  
Keyword(s):  
Abdominal Obesity ◽  
Cross Sectional Study ◽  
Strongly Correlated ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
Glomerular Function ◽  
Síndrome Metabólico ◽  
System Risk ◽  
Apparently Healthy

Introduction: Metabolic syndrome (MS) is an independent risk factor, which affects the development of chronic kidney disease, so the glomerular filtration rate (GFR) as an indicator of glomerular function in patients with and without MS who attended the outpatient clinic “los Grillitos, sector Caña de Azucar”. Materials and Methods: A comparative, correlational, cross-sectional study was conducted in a non-probability sample of convenience consisting of 60 patients with MS diagnosed according to the criteria Panel ATP III, and 60 apparently healthy individuals, whom the GFR was determined by the Cockcroft-Gault as well as clinical and biochemical parameters for the diagnosis of MS. Results: Out of the total patients evaluated, 37 (30.7%) showed alterations that put them in grades G2 and G3 system risk stratification of CKD, of these 18 and 19 corresponded to patients with and without MS respectively. Glomerular Hyperfiltration (> 120 mil / min) it was found in both groups 28 (46.7%) and 24 (40%) cases of patients with and without MS respectively. The glomerular function was strongly correlated with abdominal obesity and high levels of stress arterial. As for the number of criteria and its relationship to the level of kidney damage present, not a firm to increase the latter with respect to the first (p=0.385) trend was observed. Conclusion: The change in the glomerular function is not directly related to the MS but with its components, specifically abdominal obesity and hypertension.

scholarly journals Dysfunctional Adiposity Index as a Useful Clinical Tool for Early Identification of Adipose Tissue Morpho-Functional Abnormalities and Cardiometabolic Disorders in Apparently Healthy Subjects

2020 ◽  
Author(s):  
Juan Reyes-Barrera ◽  
Victor H. Sainz-Escárrega ◽  
Aida X. Medina-Urritia ◽  
Esteban Jorge-Galarza ◽  
Horacio Osorio-Alonso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adipose Tissue ◽  
Clinical Practice ◽  
Early Identification ◽  
Healthy Subjects ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adiposity Index ◽  
Apparently Healthy

Abstract BackgroundCompared to body mass index (BMI), waist circumference (WC), and adiposity measurements, adipose tissue morpho-functionality evaluations are more consistent predictors of cardiometabolic abnormalities. However, these evaluations require determination of adipokines and other non-routine biochemical parameters, which is not feasible in clinical practice. The present study establishes dysfunctional adiposity index (DAI) as a simple, accessible, and reliable marker of early adipocytes morpho-functional abnormalities and cardiometabolic diseases.MethodsTo establish the DAI constant parameters, 340 subjects (134 males and 206 females) without cardiovascular risk factors were selected from a cross-sectional study. Then, DAI was calculated in 36 healthy subjects who underwent subcutaneous adipose tissue biopsy, for whom adipocytes number and size, body composition, circulating adipokines, glucose, insulin, and lipids were also determined. The correlation of DAI with adipocyte morphology (size/number of adipocytes) and functionality (adiponectin/leptin ratio) was analyzed. The receiver operating characteristic curve was used to define the optimal DAI cut-off point to identify metabolic abnormalities. Finally, the independent association of DAI with cardiometabolic abnormalities was determined in 1418 subjects from the cross-sectional study through multivariate analyses.ResultsThe constant parameters to calculate the DAI were [WC/[22.79+[2.68*BMI]]]*[triglycerides (TG, mmol/L)/1.37]*[1.19/high density lipoprotein-cholesterol (HDL-C, mmol/L)] for males, and [WC/[24.02+[2.37*BMI]]]*[TG(mmol/L)/1.32]*[1.43/HDL-C(mmol/L)] for females. In subjects underwent biopsy, DAI correlated with adipocytes mean area (r=0.358; p=0.032), adipocyte number (r=-0.381; p=0.024), adiponectin/leptin ratio (r=-0.483; p=0.003), and systemic inflammation markers. Compared to BMI, WC, and visceral fat, DAI was the only determination associated with insulin resistance (area under the curve: 0.743; p = 0.017). In the cross-sectional study, DAI ≥1.065 was independently associated with diabetes (OR: 1.96; 95%CI: 1.36-2.84), non-alcoholic fatty liver disease (OR: 2.57; 95%CI: 1.98-3.33), subclinical atherosclerosis (OR: 1.74; 95%CI: 1.02-2.94), and hypertension (OR: 1.44; 95%CI: 1.10-1.88).ConclusionsThe present study establishes the constant parameters to calculate the DAI and highlights that a DAI ≥ 1.065 is associated with early cardiometabolic abnormalities independently of adiposity and other risk factors. Since DAI is calculated using accessible parameters routinely used in the clinic, this indicator can be easily incorporated in clinical practice for the early identification of adipose tissue abnormalities in apparently healthy subjects.

scholarly journals The association between household food insecurity and obesity in Mexico: a cross-sectional study of ENSANUT MC 2016

2021 ◽  
pp. 1-11
Author(s):  
Rosa Elena Ponce-Alcala ◽  
Jose Luis Ramirez-Garcia Luna ◽  
Teresa Shamah-Levy ◽  
Hugo Melgar-Quiñonez
Keyword(s):  
Food Insecurity ◽  
Abdominal Obesity ◽  
Urban Areas ◽  
National Level ◽  
Cross Sectional Study ◽  
Household Food Insecurity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Household Food ◽  
Mexican Adults

Abstract Objective: To examine the association between household food insecurity and overweight, obesity and abdominal obesity in Mexican adults. Design: Cross-sectional study. Setting: We analysed data from the Mexican Halfway National Health and Nutrition Survey 2016, a nationally representative survey that accounted for rural and urban areas in four regions of Mexico: North, Centre, Mexico City and South. Participants: Adults from 20 to 59 years old (n 5456, which represents 45 804 210 individuals at the national level). Results: 70·8 % of the Mexican adults had some degree of household food insecurity. This situation showed larger proportions (P < 0·05) among indigenous people, those living in a rural area, in the Southern region or the lowest socio-economic quintiles. The prevalence of obesity and abdominal obesity was higher in female adults (P < 0·001), with the highest proportions occurring among those experiencing severe household food insecurity. Among women, mean BMI and waist circumference were higher as household food insecurity levels increased (P < 0·001). According to multivariate logistic regression models, severe household food insecurity showed to be positively associated with obesity (OR: 2·36; P = 0·001) in Mexican adult females. Conclusions: Our findings confirm the association between household food insecurity and obesity among Mexican women. Given the socio-demographic characteristics of the food-insecure population, it is alarming that prevailing socio-economic inequalities in the country might also be contributing to the likelihood of obesity. Therefore, it is crucial to maintain and bolster surveillance systems to track both problems and implement adequate policies and interventions.

scholarly journals Vertebrogenic back pain syndrome in children 9–17 years with spinal deformities

2019 ◽  
Vol 7 (1) ◽  
pp. 5-14 ◽  
Author(s):  
Marchel S. Vetrile ◽  
Aleksandr A. Kuleshov ◽  
Nikolai A. Eskin ◽  
Mikhail B. Tsykunov ◽  
Alexey I. Kokorev ◽  
...  
Keyword(s):  
Back Pain ◽  
Children And Adolescents ◽  
Pain Syndrome ◽  
Cross Sectional Study ◽  
Spinal Deformities ◽  
Age Group ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
X Ray

Aim. We defined the prevalence of back pain in children and adolescents aged 917 years with spinal deformities. Material and methods. The cross-sectional study included 230 students with different spinal deformities aged 917 years. The prevalence of back pain, intensity, location, and situations in which it occurred were assessed via questionnaire. Results. Among 230 respondents, 186 (80.9%) admitted that they had experienced back pain (mainly in the lumbar spine) at various frequencies within the year preceding the study. Mild pain was prevalent (71% of respondents). Girls experienced back pain significantly more frequently than boys. Conclusions. Back pain in children and adolescents requires clinical and instrumental examination, including X-ray. Back pain is a frequent phenomenon in children with different spinal deformities. Тhe incidence of pain in children and adolescents with spinal deformities in our study is statistically higher than that of healthy individuals of the same age group.

Width and thickness of the gingiva in periodontally healthy individuals in a central Indian population: a cross-sectional study

2021 ◽  
Author(s):  
Pradeep S. Anand ◽  
Abhinav Bansal ◽  
Balaji R. Shenoi ◽  
Kavitha P. Kamath ◽  
Namitha P. Kamath ◽  
...  
Keyword(s):  
Indian Population ◽  
Cross Sectional Study ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional

The Relationship Between Recommended and None Recommended Food Scores on Cardiovascular Risk Factors in Obese and Overweight Adult Women: A Cross Sectional Study

2020 ◽  
Author(s):  
Maryam Sabbari ◽  
Atieh Mirzababaei ◽  
Farideh Shiraseb ◽  
Khadijeh Mirzaei
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Abdominal Obesity ◽  
Lower Risk ◽  
Cross Sectional Study ◽  
Composition Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

Abstract Objective: No studies have examined the relationship between recommended food score (RFS), none recommended food score (NRFS) and cardiovascular risk factors. This study was conducted to evaluate the association of RFS and NRFS with cardiovascular risk factors in overweight and obese women.Methods: This cross-sectional study was performed on 379 overweight and obese (BMI ≥25 kg/m2) women aged 18-48 years. Anthropometric measurements and body composition analysis were assessed in all participants. Dietary intake was assessed by a valid and reliable food frequency questionnaire (FFQ) containing 147 items and RFS and NRFS calculated. Biochemical assessments including TC, HDL, LDL, TG, FBS, insulin, HOMA-IR and hs-CRP were quantified by ELISA.Results: The mean age and BMI of participants were 36.73±9.21 (y) and 31.17±4.22 (kg/m²) respectively. Binary logistic analysis showed that participants in the highest quartile of the RFS compared to the lowest quartile had 82% lower risk for Hypertriglyceridemia [OR=0.18, 95%CI=0.06-0.53, P=0.002] and 91% lower risk for abdominal obesity [OR=0.09, 95%CI=0.008-1.04, P=0.05]. in addition, Participants who were in the highest quartile of the RFS compared to the lowest quartile had lower HOMA-IR [OR=0.29, 95%CI=0.08-1.00, P=0.05]. subjects with high adherence to the NRFS had lower HDL [OR=2.11, 95%CI=1.08-4.12, P=0.02] and higher risk for Hypertriglyceridemia [OR=2.95, 95%CI=1.47-5.94, P=0.002] compared to low adherence. Conclusions: There was an inverse significant association between adherence to RFS and risk of Hypertriglyceridemia, insulin resistance, and abdominal obesity. There was a significant association between NRFS and Hypertriglyceridemia, and also we found an inverse relationship between NRFS and HDL.

scholarly journals Midnight salivary cortisol secretion and the use of antidepressants were associated with abdominal obesity in women with type 1 diabetes: a cross sectional study

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Eva Olga Melin ◽  
Magnus Hillman ◽  
Maria Thunander ◽  
Mona Landin-Olsson
Keyword(s):  
Type 1 Diabetes ◽  
Logistic Regression ◽  
Abdominal Obesity ◽  
Salivary Cortisol ◽  
Cross Sectional Study ◽  
Cortisol Secretion ◽  
Multiple Logistic Regression ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Abdominal obesity is a risk factor for cardiovascular disease. The aim was to explore the influence of midnight salivary cortisol (MSC), antidepressants and sex on abdominal obesity in type 1 diabetes (T1D). We controlled for physical inactivity, smoking, depression and alexithymia. Methods Cross sectional study of 190 T1D patients (86 women/104 men, 18–59 years, diabetes duration 1–55 years), consecutively recruited from one specialist diabetes outpatient clinic. Anthropometrics, blood pressure, saliva and blood samples were collected, supplemented with data from electronic medical records. Depression and alexithymia were assessed by self-report instruments. MSC (nmol/l) was categorised into 3 levels: high MSC: (≥ 6.7) (n = 64); intermediate MSC: ≥ 3.7− < 6.7) (n = 64); low MSC (< 3.7) (n = 62). Abdominal obesity was defined as waist circumference (meters) ≥ 0.88 for women and as ≥ 1.02 for men. Multiple logistic regression analyses (Backward: Wald) were performed. The Hosmer and Lemeshow test for goodness-of-fit and Nagelkerke R2 were used to evaluate each multiple logistic regression analysis model. Results The prevalence of abdominal obesity was three times higher in the women than in the men (24% versus 8%) (p = 0.002). Antidepressants were used by 10% of the women and by 4% of the men (p = 0.09). The prevalence of high MSC was 1.7 times higher in the women (43% versus 26%); the prevalence of both intermediate MSC (28% versus 38%) and low MSC (29% versus 36%) were lower in the women (p = 0.048). Significant associations with abdominal obesity were for all 190 patients: female sex (adjusted odds ratio (AOR) 3.4 (confidence interval (CI) 1.4–8.2)) and the use of antidepressants (AOR 4.3 (CI 1.2–14.8)); for the 86 women: high MSC (AOR 18.4 (CI 1.9–181)) and use of antidepressants (AOR 12.2 (CI 2.0–73.6)); and for the 104 men: alexithymia (AOR 5.2 (CI 1.1–24.9)). Conclusions Clear sex differences were demonstrated with a distinct higher prevalence of abdominal obesity, as well as a distinct higher prevalence of high midnight salivary cortisol in the women with type 1 diabetes. High midnight salivary cortisol secretion and the use of antidepressants were independent risk factors for abdominal obesity in the women.

scholarly journals Fibrinogen status in relapse and remission of childhood nephrotic syndrome

2016 ◽  
Vol 46 (4) ◽  
pp. 149
Author(s):  
Veronica Lily Limantara ◽  
Ida Bagus Mudita ◽  
I Ketut Suarta
Keyword(s):  
Nephrotic Syndrome ◽  
Serum Albumin ◽  
Cross Sectional Study ◽  
Fibrinogen Concentration ◽  
Strongly Correlated ◽  
Sectional Study ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Remission Status ◽  
The Mean

Objective To evaluate fibrinogen concentration of relapsing neph-rotic syndrome (NS) in children, and to investigate relationshipbetween fibrinogen with albumin and cholesterol.Methods A cross-sectional study among NS patients admitted topediatric outpatient clinic and pediatric ward at Sanglah Hospital,Denpasar, from November 1, 2003 to January 31, 2004. All pa-tients were evaluated for clinical and laboratory findings of relapseand remission, including edema, proteinuria, serum albumin, totalcholesterol, as well as total platelet count and fibrinogen concen-tration to evaluate coagulation parameters in nephrotic patients.Results There were 36 patients with the mean age of 7.4 (SD 2.3)years included in this study. Mean fibrinogen concentration in re-lapse state was 671.8 (SD 102.7) mg/dl, while in remission statewas 255.2 (SD 50.5 mg/dl); the mean difference was 416.6 mg/dl(95% CI 362.9;470.4; P<0.001). Fibrinogen was inversely andstrongly correlated with serum albumin concentrations (r=-0.91;P<0.001). Fibrinogen was positively and strongly correlated to to-tal cholesterol (r=0.80; P<0.001). Using multiple regression analy-sis, it was shown that only relapse/remission status was signifi-cantly associated with fibrinogen concentration (P<0.001).Conclusion Fibrinogen status is significantly correlated with re-lapse and remission status of NS in childhood patients.

scholarly journals No QTc Prolongation in Girls and Women with Turner Syndrome

2020 ◽  
Vol 105 (11) ◽  
Author(s):  
Iris D Noordman ◽  
Anthonie L Duijnhouwer ◽  
Misty Coert ◽  
Melanie Bos ◽  
Marlies Kempers ◽  
...  
Keyword(s):  
Turner Syndrome ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Qtc Interval ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Qtc Prolongation ◽  
Genetic Condition ◽  
Cross Sectional ◽  
Qt Intervals

Abstract Context Turner syndrome (TS) is a genetic condition that is reported to be associated with a prolonged rate-corrected QT (QTc) interval. Objectives To evaluate the prevalence of QTc prolongation in patients with TS, to compare their QTc intervals with healthy controls, and to investigate whether QTc prolongation is associated with a monosomy 45,X karyotype. Method Girls (n = 101) and women (n = 251) with TS visiting our center from 2004–2018 were included in this cross-sectional study. QT intervals of 12-leaded electrocardiograms were measured manually, using Bazett’s and Hodges formulas to correct for heart rate. A QTc interval of &gt;450 ms for girls and &gt;460 ms for women was considered prolonged. Corrected QT (QTc) intervals of patients with TS were compared to the QTc intervals of healthy girls and women from the same age groups derived from the literature. Results In total, 5% of the population with TS had a prolonged QTc interval using Bazett’s formula and 0% using Hodges formula. Mean QTc intervals of these patients were not prolonged compared with the QTc interval of healthy individuals from the literature. Girls showed shorter mean QTc intervals compared with women. We found no association between monosomy 45,X and prolongation of the QTc interval. Conclusions This study shows that the QTc interval in girls and women with TS is not prolonged compared with the general population derived from the literature, using both Bazett’s and Hodges formulas. Furthermore, girls show shorter QTc intervals compared with women, and a monosomy 45,X karyotype is not associated with QTc prolongation.

scholarly journals The Association between Physical Fitness Performance and Abdominal Obesity Risk among Taiwanese Adults: A Cross-Sectional Study

2020 ◽  
Vol 17 (5) ◽  
pp. 1722 ◽  
Author(s):  
Po-Fu Lee ◽  
Chien-Chang Ho ◽  
Nai-Wen Kan ◽  
Ding-Peng Yeh ◽  
Yun-Chi Chang ◽  
...  
Keyword(s):  
Physical Fitness ◽  
Abdominal Obesity ◽  
Population Analysis ◽  
Multiple Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Step Test ◽  
Sectional Study ◽  
Obesity Risk ◽  
Cross Sectional ◽  
New Perspective

The present study aims to investigate the associations between physical fitness performance and abdominal obesity risk among Taiwanese adults. We conducted a cross-sectional study and reviewed the data derived from the National Physical Fitness Survey in Taiwan (HPFSIT). Data from a total of 62,486 respondents aged 23–64 years were collected in this study. The participants completed a standardized structural questionnaire and a series of anthropometric characteristics (body mass index and waist-to-hip ratio) and physical fitness (3-min step tests, 1-min sit-up tests, and sit-and-reach tests) assessments. Waist circumference was used to define abdominal obesity status. A multiple logistic regression analysis was conducted. Our results presented almost entirely significant associations (except for women) on the 3-min step test. Moreover, the results suggest that muscular strength, endurance, and flexibility may be effective predictors of abdominal obesity among men and women, whereas cardiorespiratory fitness predicted abdominal obesity only in men. According to the results of this study, the fitness–abdominal obesity associations are minor based on a mixed population analysis. However, dose–response relationships have been observed. The present study provides a new perspective by using different types of fitness performance to predict abdominal obesity.

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