Factors associated with resistant hypertension in a large cohort of hypertensive patients: the Pol-Fokus study

Primary aldosteronism (PA) is not only a leading cause of secondary and resistant hypertension, but is also quite frequent in unselected hypertensive patients. Moreover, PA is associated with increased cardiovascular risk, which is disproportionate to BP levels. In addition, timely diagnosis of PA and prompt initiation of treatment attenuate this increased risk. On the other hand, there are limited data regarding the usefulness of screening for PA in all asymptomatic or normokalemic hypertensive patients. More importantly, until now, no well-organized, large-scale, prospective, randomized controlled trial has proved the effectiveness of screening for PA for improving clinical outcome. Accordingly, until more relevant data are available, screening for PA should be considered in hypertensive patients with spontaneous or diuretic-induced hypokalemia as well as in those with resistant hypertension. However, screening for PA in all hypertensive patients cannot be currently recommended.

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Determination of risk factors associated with inflammation in hypertensive patients with type-2 diabetes mellitus in a Palestinian Diabetes Study

Current Medical Research and Opinion ◽

10.1080/03007995.2021.1941826 ◽

2021 ◽

pp. 1-1

Author(s):

Mohammed S. Ellulu ◽

Ihab A. Naser ◽

Sahar M. Abuhajar ◽

Ahmed A. Najim

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Hypertensive Patients ◽

Factors Associated

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Factors associated with prognostic or treatment outcomes in HIV/AIDS patients with and without hypertension in Eswatini

Scientific Reports ◽

10.1038/s41598-021-92185-0 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Sabelo Bonginkosi Dlamini ◽

Hans-Uwe Dahms ◽

Ming-Tsang Wu

Keyword(s):

Viral Load ◽

P Value ◽

Aids Patients ◽

Large Hospital ◽

Hypertensive Patients ◽

Factors Associated ◽

Cell Counts ◽

Cd4 Cell Counts ◽

Cd4 Cell ◽

Hiv Aids

AbstractNon-communicable diseases are increasing faster in HIV/AIDS patients than in the general population. We studied the association between hypertension and other possible confounding factors on viral load and CD4-cell counts in hypertensive and non-hypertensive HIV/AIDS patients receiving antiretroviral therapy (ART) at a large hospital in Eswatini over a 4-year period. We performed a retrospective longitudinal review of the medical records of 560 ART patients divided into non-hypertension and hypertension groups (n = 325 and n = 235) from July 27 to September 8, 2018. Generalized Estimated Equation was used to analyze the longitudinal data. Hypertensive patients were more likely to have improved CD4-cell counts than non-hypertensive patients (OR = 1.83, [1.37–2.44]). ART patients with hypertension were more likely to have detectable viral loads, though not significant (OR = 1.37 [0.77–2.43]). In non-hypertensive patients, second line ART was significantly associated with viral load (OR = 8.61 [2.93–25.34]) and adverse side effects (OR = 3.50 [1.06–11.54]), while isoniazid preventive therapy was significantly associated with CD4-cell counts (OR = 1.68 [1.16–2.45]). In hypertensive patients, factors associated with viral load were WHO HIV stage (OR = 2.84 [1.03–7.85]) and adherence (OR = 8.08 [1.33–49.04]). In both groups, CD4-cell counts significantly and steadily increased over time (p-value < 0.001). Results show a significant association between hypertension and CD4 cell counts but not viral load. In ART patients with and without hypertension, the factors associated with prognostic markers were different. More attention may need to be paid to ART patients with well controlled HIV status to monitoring and controlling of hypertension status.

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Incidence and persistence of resistant hypertension among treated hypertensive patients: insights from a 4-year follow-up study

European Heart Journal ◽

10.1093/eurheartj/eht309.3613 ◽

2013 ◽

Vol 34 (suppl 1) ◽

pp. 3613-3613

Author(s):

A. Kordalis ◽

C. Tsioufis ◽

A. Kasiakogias ◽

C. Thomopoulos ◽

I. Dima ◽

...

Keyword(s):

Resistant Hypertension ◽

Hypertensive Patients ◽

Follow Up Study

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Systemic lupus erythematosus in three ethnic groups: IV. Factors associated with self-reported functional outcome in a large cohort study

Arthritis & Rheumatism ◽

10.1002/1529-0131(199908)12:4<256::aid-art4>3.0.co;2-g ◽

1999 ◽

Vol 12 (4) ◽

pp. 256-266 ◽

Cited By ~ 45

Author(s):

Alan W. Friedman ◽

Graciela S. Alarc�n ◽

Gerald McGwin ◽

Karin V. Straaton ◽

Jeffrey Roseman ◽

...

Keyword(s):

Systemic Lupus Erythematosus ◽

Cohort Study ◽

Functional Outcome ◽

Ethnic Groups ◽

Lupus Erythematosus ◽

Large Cohort ◽

Systemic Lupus ◽

Factors Associated ◽

Large Cohort Study

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Behavioral Factors Associated with Medication Nonadherence in Patients with Hypertension

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18189614 ◽

2021 ◽

Vol 18 (18) ◽

pp. 9614

Author(s):

Shu-Mei Chang ◽

I-Cheng Lu ◽

Yi-Chun Chen ◽

Chin-Feng Hsuan ◽

Yin-Jin Lin ◽

...

Keyword(s):

Protective Factor ◽

Multivariable Logistic Regression Analysis ◽

Behavioral Factors ◽

Medication Nonadherence ◽

Hypertensive Patients ◽

Factors Associated ◽

Diet Supplements ◽

Increased Risk ◽

Medication Dose ◽

Male Sex

Medication nonadherence is associated with an increased risk of complications in hypertensive patients. We investigated behavioral factors associated with medication nonadherence in hypertensive patients in southern Taiwan. Using questionnaires, we collected data regarding clinicodemographic characteristics and nonadherence behaviors from 238 hypertensive patients. We assessed the self-reported prevalence of specific behaviors of medication nonadherence and investigated factors associated with each behavior using multivariable logistic regression analysis. The most common behavior of medication nonadherence was forgetting to take medication (28.6%), followed by discontinuing medication (9.2%) and reducing the medication dose (8.8%). Age ≥ 65 years (adjusted odds ratio [aOR] = 0.32, 95% confidence interval [CI] = 0.15–0.69) and male sex (aOR = 2.61, CI = 1.31–5.19) were associated with forgetting to take medication. The presence of comorbidities (diabetes, kidney disease, or both) and insomnia (aOR = 3.97, 95% CI = 1.30–12.1) was associated with reducing the medication dose. The use of diet supplements was associated with discontinuing the medication (aOR = 4.82, 95% CI = 1.50–15.5). Compliance with a low oil/sugar/sodium diet was a protective factor against discontinuing medication (aOR = 0.14; 95% CI = 0.03–0.75). The most pervasive behavior associated with medication nonadherence among hypertensive patients was forgetting to take medication. Age <65 years, male sex, comorbidities, insomnia, noncompliance with diet, and the use of dietary supplements were specifically associated with medication nonadherence.

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Assessment of self-care practices among hypertensive patients: a clinic based study in rural area of Singur, West Bengal

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20175794 ◽

2017 ◽

Vol 5 (1) ◽

pp. 262 ◽

Cited By ~ 1

Author(s):

Aparajita Dasgupta ◽

Sembagamuthu Sembiah ◽

Bobby Paul ◽

Ayon Ghosh ◽

Bijit Biswas ◽

...

Keyword(s):

Public Health ◽

Logistic Regression ◽

Rural Area ◽

Lifestyle Modification ◽

Self Care ◽

The Self ◽

Health Concern ◽

Hypertensive Patients ◽

Factors Associated ◽

Care Practices

Background: Hypertension, also known as high blood pressure is a global public health concern. It is an important modifiable risk factor for cardiovascular disease and stroke. It remains silent, being generally asymptomatic during its clinical course and it accounts for a large proportion of cardiovascular deaths; lifestyle modification is the first line of intervention for all patients with hypertension, yet it was never been empirical. The aim of the study was to assess the pattern of self-care practices, if any and also to find out the factors associated with it, among the hypertensive patients in the outpatient department. Methods: A clinic-based, observational, cross-sectional study was conducted at health center under RHU & TC, Singur, which is the rural field practice area of All India Institute of Hygiene and Public Health, Kolkata among 124 hypertensive subjects. Binary logistic regression was done to find out the factors associated with the self-care practices using SPSS software. Results: In the present study, 62.9% of study participants suffering from hypertension had unfavourable self-care practices. Logistic regression showed age above 60 years (OR-3.1), primary level education (OR-5.6), poor socio economic status (OR-2.4), widow/separated (OR-3.3) and people with self-perceived poor health status (OR-2.8)had significant association with unfavourable self-care practices. After adjusting with other variables, age (AOR-2.3) and education (AOR-3.8) remained significant predictor of outcome. Conclusions: The findings revealed that the self-care practices among hypertensive patients were unfavourable in rural area. This calls for a deep need in increasing the awareness about healthy lifestyle among hypertensive patients. This study provides key elements to affect policy changes and social interventions.

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