scholarly journals PROFIL VITAMIN D PADA PASIEN ASMA DAN NON-ASMA DEWASA DI SURABAYA

2017 ◽  
Vol 12 (1) ◽  
pp. 106
Author(s):  
Rivan Virlando Suryadinata ◽  
Amelia Lorensia ◽  
Anugrah Putri Aprilia
Keyword(s):  
Vitamin D ◽  
Young Adult ◽  
Bronchial Epithelium ◽  
Chronic Inflammatory Disease ◽  
Cross Sectional ◽  
Change Behavior ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Asthma Patients ◽  
Asthma Group

Asthma is a chronic inflammatory disease on respiratory tract, where airflow are retricted dan chronic inflammation result in bronchial epithelium damage. Pathogenesis mechanism of asthma is influenced by vitamin D as an immunomodulator. The low vitamin D levels can trigger asthmaexacerbations. The study aimed to determine the levels of vitamin D from blood sample in astmatic young adult in compared to non astmatics, to identify the risk of vitamin D deficiency, that can aggravate asthma symptoms. The study used an observational analytic cross sectional design. Subjects were chosenthrough a purposive sampling method. Population was young adults in Surabaya. Subjects were 26 asthmatic patientsdan 26 non-asthmatic young adult in South Surabaya that fulfilled inclusion dan exclusion criteria. The study was conducted in May 2015 to July 2016. The results showed vitamin Dlevels in the asthma group 24.5 ± 2.95 while in the non-asthma group 20.52 ± 2.47. All respondents in both groups had vitamin D levels > 30 ng/mL (normal value), dan there was significant difference between levels of vitamin D in asthma dan non-asthma patients (p < 0.05). Therefore, increasing knowledge about the importance of vitamin D should be done, because it can change behavior through lifestyle, diet dan physical activity in the community.Keywords: asthma, vitamin D

scholarly journals Alert for bone alterations and low serum concentrations of vitamin D in patients with intestinal inflammatory disease

2017 ◽  
Vol 63 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Lorete Maria da Silva Kotze ◽  
◽  
Carolina Tabata Costa ◽  
Murilo Franco Cavassani ◽  
Renato Mitsunori Nisihara ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Bone Changes ◽  
Bowel Diseases ◽  
Intestinal Inflammatory Disease ◽  
Irritable Bowel

Summary Background: Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation of the intestine that can reduce the absorption of nutrients such as vitamin D and calcium. Objective: To investigate bone alterations and serum levels of vitamin D in patients with IBD. Method: This was a cross-sectional study based on a review of medical records of patients from a private office in Curitiba, PR, Brazil. Serum levels of vitamin D and bone densitometry were measured at diagnosis of IBD. A total of 105 patients were included; 38 (58.4%) with CD; 27 (41.6%) with UC and 40 with irritable bowel syndrome (IBS) as comparison group. Results: When compared to patients with UC, CD patients showed a higher prevalence of bone alterations, being 15.8% with osteoporosis and 36.8% with osteopenia. In UC, bone alterations occurred in 29.6% of cases, 3.7% with osteoporosis and 25.9% with osteopenia. As for vitamin D levels, among CD patients, 10.5% had vitamin deficiency, 65.8% insufficiency and 23.7% were sufficient. In UC, 7.4% of cases had deficiency, 74.1% insufficiency and 18.5% had sufficient serum levels of vitamin D. In the group with IBS, deficiency was observed in 17.5% of cases, insufficiency in 55% and sufficiency in 27.5% of them. There was no significant difference between groups. Conclusion: IBD patients have a high prevalence of bone changes, especially those with CD. Serum levels of vitamin D are below the recommended in all the evaluated groups.

scholarly journals HUBUNGAN KADAR VITAMIN D DALAM DARAH DENGAN KEJADIAN OBESITAS PADA SISWA SMA PEMBANGUNAN PADANG

2019 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Sesmi Nanda Oktavia
Keyword(s):  
Vitamin D ◽  
Body Height ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Elisa Method ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
The Relationship

The obesity cases in the world, including Indonesia is increasing. This condition also occurs to senior high school (SMA) Pembangunan students in Padang. There are several factors affecting the obesity occurrence, one them is the level of vitamin D serum. The aims of this study was to identify the relationship between vitamin D levels in the blood and the obesity occurrence.This research used cross sectional study design from March to June 2017. The samples were 82 students from SMA Pembangunan in Padang conducted by using simple random sampling. The level of obesity was determined by measuring body height and weight. The z zscore BMI/age was calculated by using the WHO antro-plus program while the vitamin D level was measured by ELISA method. The statistical analysis used independent sample t-test.The result shows that there is significant difference of the average vitamin D level in the blood of students with obesity compared to normal students (p=0,025). There is also difference in proportion of obesity occurence between the respondents who lack Vitamin D compared to those with adequate level of vitamin D (p=0,020).Based on the research, it is concluded that there is significant relationship between the level of vitamin D in the blood and the occurrence of obesity. Suggestion further research on the effect of vitamin D on obesity needs to be conducted.

scholarly journals Vitamin D level as a predictor of pneumonia and asthma in children less than 5 years of age

2020 ◽  
Vol 7 (7) ◽  
pp. 1593
Author(s):  
Neha Sharma ◽  
Anuj Shamsher Sethi ◽  
R. S. Sethi
Keyword(s):  
Vitamin D ◽  
P Value ◽  
Healthy Children ◽  
Outpatient Services ◽  
Common Chronic Disease ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Asthma Patients ◽  
Asthma In Children ◽  
Deficient Level

Background: Childhood pneumonia is a global health problem .It the leading cause of death for children under the age of five years. 95% of all pneumonia cases under the age of five occurs in developing countries. Asthma remains the most common chronic disease of childhood in the world. The observation that vitamin D deficiency and asthma share risk factors such as urban residence, obesity and African American ethnicity has generated interest in exploring a link between these two conditions. This study was taken up to assess the role of vitamin D as a predictor of pneumonia and asthma in children less than 5 years of age.Methods: A prospective observational case control study was conducted in MLB Medical college, Jhansi from January 2015 to December 2016 (1 year 11 months). A total of 60 children including 30 asthma cases, 20 pneumonia cases and 10 controls, aged, 6-60 months were enrolled. Controls were healthy children attending outpatient services for immunization.Results: The mean age of the pneumonia patient was 1.5 years, while mean age in asthma patients was 3.1yrs. Ratio of male and female in pneumonia cases was1.5:1, while is asthma ratio was 2:1. In our study 45% pneumonia cases had deficient level of vitamin D (<20ng/ml) and mean level was 11.08±4.68 while 40% of control had deficient level of vitamin D and mean level was 16.04±1.61, p value was 0.0166 and there was significant difference in both the groups. In Asthma cases 53.33% patient had deficient level of vitamin-D and mean level was 10.62±2.908 as compared to 40% control (mean : 16.04±1.62) ‘p’ value was <0.0001 and was highly significant.Conclusions: Our study has illustrated that vitamin-D levels were significantly low in pneumonia and asthma patients as compared to control.

scholarly journals Association between serum 25-hydroxy vitamin D level and menstrual cycle length and regularity: A cross-sectional observational study

2021 ◽  
Author(s):  
Vinita Singh ◽  
Neelam Tamar ◽  
Zamir Lone ◽  
Esha Das ◽  
Rajshree Sahu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Menstrual Cycle ◽  
Vitamin D Deficiency ◽  
Cycle Length ◽  
Menstrual Disorders ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Menstrual Irregularities ◽  
25 Hydroxy Vitamin D

Background: Research examining the role of vitamin D deficiency and the development of menstrual disorders in women is of widespread interest. Studies have been published showing that supplementation with high-dose vitamin D can lead to the restoration of the menstrual cycle. We lack adequate information regarding the effect of vitamin D levels on the physiology of menstruation and further on fertility in women of reproductive age due to the contradictory results reported by studies. Objective: To study the association of 25-hydroxy vitamin D with menstrual cycle characteristics including long and short cycle length and cycle irregularity. Materials and Methods: In this cross-sectional study, serum vitamin D levels of 166 women attending an outpatient department with menstrual irregularities after excluding all obvious causes of menstrual disorders (n = 83) between April-June 2019 were measured and were compared with women of similar profiles with complaints other than menstrual irregularities (n = 83). Results: A decreased level of vitamin D was associated with a 13.3 times odds of an irregular cycle (OR (95% CI): 13.30 (5.79-30.60), p < 0.001). 25-hydroxy vitamin D was not associated with age or body mass index. We found a significant difference (p < 0.001) in mean vitamin D levels among the females with irregular cycles vs. regular cycles. Conclusion: Vitamin D plays a role in the physiology of reproduction specific to the menstrual cycle and ovulation. Long-term prospective studies assessing the exact cutoff value and the exact dose of supplementation required are needed. Key words: Menstrual disturbances, Ovulation, Reproductive period, Vitamin D deficiency, Dietary supplements, Polycystic ovarian syndrome.

scholarly journals Vitamin D status in 3-6-year-old children of Mananthavady ICDS block in Wayanad, Kerala, India

2018 ◽  
Vol 5 (4) ◽  
pp. 1226
Author(s):  
Arif Mohamed Khan ◽  
T. G. Sindhu ◽  
M. Vijayakumar
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Tribal Community ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
High Prevalence ◽  
25 Oh Vitamin D ◽  
Kerala State

Background: Despite plenty of sunlight, vitamin D deficiency has been reported in both urban and rural population in India. This study was conducted to estimate the prevalence of Vitamin D deficiency in children between 3-6 years of age group belonging to Mananthavady ICDS block of Wayanad and to identify the sociodemographic variables affecting its level.Methods: This descriptive cross-sectional study was conducted from December 2014 to June 2015. 140 children were selected from 20 Anganawadis in Mananthavady ICDS block in Wayanad district of Kerala state by random methods. After taking relevant history and conducting detailed clinical examinations, blood samples were taken to assess 25(OH) Vitamin D, calcium, phosphorous and alkaline phosphatase levels. Statistical analysis was done using PASW software. Calculations of means were done using descriptive statistics and comparative analysis was done using independent T test.Results: Out of the 140 children 51 belonged to tribal community. The mean 25(OH) Vitamin D level was 22.7ng/ml. 47.1% of the population had deficient, 35% insufficient and 17.9% adequate Vitamin D levels. There was no statistically significant difference in Vitamin D levels between children of tribal and non-tribal community. There was significant increase in Vitamin D levels during summer when compared to that of winter and autumn seasons.Conclusions: There is a high prevalence of vitamin D deficiency among the rural children of 3-6-year age of Mananthavadi ICDS block. The Vitamin D levels were almost equal between the tribal and non-tribal children. Vitamin D levels are significantly higher during summer when compared to other seasons.

scholarly journals STUDY OF T-SCORE ACROSS DIFFERENT AGE GROUPS AND GENDER IN APPARENTLY HEALTHY POPULATION IN INDIA

2020 ◽  
pp. 1-3
Author(s):  
Abhishek Sinha
Keyword(s):  
Vitamin D ◽  
Age Groups ◽  
Analysis Data ◽  
Healthy Population ◽  
Mineral Density ◽  
Cross Sectional ◽  
T Score ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Males And Females

INTRODUCTION: Bone mineral density(BMD) is a common test done in our country. Traditionally, BMD has been reserved for postmenopausal females to check for risk of osteoporosis. The aim of this study is to check whether BMD score showed difference between males and females and across different age groups. Also, we tried to examine any correlation between Vitamin D and BMD values. MATERIAL AND METHODS: It was a cross-sectional observational study.118 healthy subjects of both genders were recruited. BMD was measured by dual energy X-ray absorptiometry(DEXA). Vitamin D was estimated by electrochemiluminescence. Statistical Analysis: Data was entered in to MS Excel and analyzed by STATA 12 software. Normality was analyzed. Mean and SD for all variables were calculated. Difference in T-score between males and females were calculated using T-test and T-score in different age groups was compared using one-way ANOVA test. Vitamin D levels were correlate with T-scores by Spearman's correlation test. RESULTS: Mean age of subjects was 51.31 years. Mean T-score was -1.40. Mean Vitamin D was 23.45 ng/ml. There was no significant difference between T-score of males and females. T-score was also not significantly different across age groups from 20 to 80 years. Vitamin D was not correlated with T-score in same subjects. Osteopenia was present in 74 subjects and osteoporosis in 11 subjects. DISCUSSION: Contrary to popular opinion, T-score was not different between males and females, therefore there is a need for uniform BMD criteria for both genders. Vitamin D levels alone are unreliable as they do not correlate with T-score. CONCLUSION: Thus, there is a need for revised T-score guidelines and additional tests like serum calcium, BMI, serum parathormone which needs to be done and examined together with BMD and Vitamin D to identify bone demineralization in the population.

scholarly journals Vitamin D levels in patients with bronchial asthma

2021 ◽  
Vol 9 (2) ◽  
pp. 375
Author(s):  
Chandan Sharma
Keyword(s):  
Vitamin D ◽  
Bronchial Asthma ◽  
Serum Vitamin ◽  
Persistent Asthma ◽  
Cross Sectional ◽  
Medical College ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Asthma Patients ◽  
The Mean

Background: Bronchial asthma is one of the most common chronic diseases. In India, bronchial asthma has 66% frequency of reported exacerbations. Vitamin D has action on pro-inflammatory mediators and smooth muscle function and proliferation, which has direct relevance for lung function in asthma.Methods: The cross sectional observational study was conducted in the Department of Medicine, Government Medical College Jammu for 10 months from January 2018-August 2018. 50 Patients of 18-60 years with diagnosis of bronchial asthma on the basis of clinical and radiological signs were included, while age matched 50 controls years free from any disease and morbidity were included and assessed for vitamin D levels.Results: The mean serum vitamin D level was significantly low at 26.13±4.91 ng/ml in patients, while 39.67±4.03 ng/ml was the mean vitamin D level of controls. The vitamin D levels of mild and moderate (persistent) asthma patients was seen lower than those of the controls.Conclusions: Vitamin D deficiency is highly prevalent in patients during exacerbations of bronchial asthma. It is also associated with lower lung functions and increased number of exacerbations. Thus improving vitamin D status may be effective in the prevention and treatment of bronchial asthma and exacerbations.

Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience

2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Model Assessment ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Female Sex ◽  
Vitamin D Levels

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.

Association of Vitamin D Status With Liver and Kidney Disease: A Systematic Review of Clinical Trials, and Cross-Sectional and Cohort Studies

2019 ◽  
pp. 1-13 ◽  
Author(s):  
Seyed Mostafa Parizadeh ◽  
Majid Rezayi ◽  
Reza Jafarzadeh-Esfehani ◽  
Amir Avan ◽  
Hamideh Ghazizadeh ◽  
...  
Keyword(s):  
Vitamin D ◽  
Kidney Disease ◽  
Renal Disease ◽  
Cohort Studies ◽  
Cochrane Library ◽  
Major Public Health Problem ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Beneficial Effects ◽  
Vitamin D Levels

Abstract. Background: Vitamin D deficiency (VDD) is a major public health problem. There are few comprehensive systematic reviews about the relationship between Vitamin D status and liver and renal disease in Iran. Methods: We systemically searched the following databases: Web of Science; PubMed; Cochrane Library; Scopus; Science Direct; Google Scholar and two Iranian databases (Scientific Information Database (SID) and IranMedex) up until November 2017 to identify all randomized control trials (RCTs), case control, cross-sectional and cohort studies investigating the association between vitamin D and any form of liver or kidney disease. Results: Vitamin D insufficiency, or deficiency (VDD), is highly prevalent in Iran, reports varying between 44.4% in Isfahan to 98% in Gorgan. There is also a high prevalence of VDD among patients with liver or kidney disease, and the administration of vitamin D supplements may have beneficial effects on lipid profile, blood glucose, liver function and fatty liver disease, and bone health. Low serum vitamin D levels are related with abnormalities in these laboratory and clinical parameters. Conclusion: VDD is prevalent in patients with chronic liver or renal disease in Iran. There appear to be several beneficial effects of vitamin D supplementation in vitamin D deficient patients with liver or kidney disease.

SUBLINGUAL VITAMIN D3 DRUG THERAPY IN VITAMIN D DEFICIENCY PATIENTS AT PRAVARA RURAL HOSPITAL

2019 ◽  
pp. 18-20
Author(s):  
Sanjeeva Kumar Goud T ◽  
Rahul Kunkulol
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Significant Difference ◽  
Before And After

The present study was aimed to study the effect of Sublingual Vitamin D3 on Serum Vitamin D level in Vitamin D deficiency patients. This was a cross-sectional and interventional study. All the Vitamin D deficiency patients of age 18-60years and either gender, willing to participate in the study were included. Patients who had greater than 20 ng/ml were excluded from the study. The total number of participants in our study was 200, out of these 111 males and 89 females, the mean age in our study was 51.07 ± 7.39Yrs. All volunteers were given sublingual vitamin D3 (60,000IU) in six doses every fifteen days of follow up for 3 months. The subject’s serum 25(OH)D levels were estimated before and after the treatment of sublingual vitamin D3. There was a statistically significant difference in serum vitamin D3 level before 16.61±6.71 ng/ml and after 35.80±7.80 ng/ml after treatment with Sublingual Vitamin D3. Six doses of 60,000IU of Vitamin D3 sublingual route having improved the role of serum 25(OH)D levels in the treatment of Vitamin D3 deficiency patients.Keywords: Vitamin D3; Sublingual route

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