scholarly journals HUBUNGAN KONSUMSI SUGAR-SWEETENED BEVERAGES DENGAN KEJADIAN DIABETES MELLITUS PADA LANSIA

2018 ◽  
Vol 13 (1) ◽  
pp. 49
Author(s):  
Putri Ramadhani ◽  
Trias Mahmudiono
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Sampling Technique ◽  
Control Group ◽  
Case Group ◽  
Sugar Consumption ◽  
Sugar Sweetened Beverages ◽  
Brown Sugar ◽  
Sweetened Beverages

Elderly becomes the most risky group in developing type 2 diabetes because they are more susceptible for carbohydrate metabolism disorders that can appear as diabetes. This study was aimed to determine the correlation between consumption of sugar-sweetened beverages and sex with the incidence of diabetes mellitus in the elderly. The population in this study were all elderly population (age> 60 years) in Jagir Public Health Center working area. This research used case control design with simple random sampling technique as a sampling method. The number of samples was 78 respondents with 39 samples of case group and 39 samples of control group. Data were analyzed using linear regression and logistic regression test. The results showed that there was a correlation between the consumption of SSBs and the incidence of diabetes mellitus in elderly (p = 0.000; OR = 9.375). Female elderly consumed more SSBs than men elderly (female's sugar consumption 26.9%, brown sugar 69.2%, syrup 75.6% and sachet drinks 73.1%, while mal’s sugar consumption 9%, brown sugar 20.5%, syrup 16.7% and sachet drinks 15.4%). In conclusion, this research revealed consumption of SSB’s was higher in female elderly and SSB’s consumption was correlated with the incidence of type 2 diabetes mellitus.

scholarly journals Bioinformatic Analysis of Evolutional Conservatism and Functional Significance of Microsatellite Alleles of Human 14Q13.2 Region Associated with Type 2 Diabetes Mellitus

2008 ◽  
Vol 62 (3) ◽  
pp. 91-102 ◽  
Author(s):  
Tatjana Sjakste ◽  
Ilva Poudžiunas ◽  
Valdis Pīrāgs ◽  
Māris Lazdiñš ◽  
Nikolajs Sjakste
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Functional Significance ◽  
Bioinformatic Analysis ◽  
Control Group ◽  
Case Group ◽  
Control Groups ◽  
And Control ◽  
Microsatellite Alleles

Bioinformatic Analysis of Evolutional Conservatism and Functional Significance of Microsatellite Alleles of Human 14Q13.2 Region Associated with Type 2 Diabetes Mellitus The paper deals with bioinformatic and statistical analysis of the possible functional significance of the previously shown association of several microsatellite alleles in intron 6 of the human proteasome core particle PSMA6 gene (HSMS006) and four other microsatellites localised upstream in human chromosome 14q13.2 (HSMS801, HSMS702, HSMS701, HSMS602) with type 2 diabetes mellitus in Latvia and Botnia, Finland. Genotype analysis revealed that (CAA)8/(CAA)8 homozygotes of the HSMS602 marker were never found in Type 2 diabetes patients, although 6.56% of the individuals from the control groups were the (CAA)8/(CAA)8 homozygotes. For the HSMS801 marker the (AC)21/(AC)23 genotype was never found in the case group and in the control group it was detected with a frequency 4.40%; these differences were statistically significant (P < 0.05). In contrast to the Latvian population, the distribution of genotype frequencies in cases and controls taken from the Botnian dataset was almost similar. Haplotype analysis showed that in the Latvian population besides haplotypes including alleles differently represented in case and control groups, a combination of some alleles almost equally represented in both groups formed combinations that were more characteristic of either the case group or the control group. This indicates probable independent functional significance of these haplotypes that warrants further investigation. In the Botnian population, more allele combinations were observed, and the distribution of haplotypes in case and control groups differed from that observed in Latvia. The observed haplotype distributions might reflect differences between the studied populations: a homogenous and isolated Botnian vis-à-vis a mixed Latvian population. Linkage disequilibrium (LD) analysis of data on the Latvian population revealed nine of ten two-allele combinations manifesting a high LD. HSMS006 and HSMS602 combination had a low LD; among the analysed markers these were situated at the largest distance from one another. Data on the Botnian population showed that haplotypes in eight of ten combinations had a high LD, including the HSMS006 and HSMS602 combinations. It appears that the two populations differ also in linkage disequilibrium of two-loci haplotypes. Theoretical analysis of a potential functional role of the polymorphisms indicated the significance of the microsatellite length of HSMS602 and HSMS006 for the formation of DNA hairpins. The whole genomic region appears to be conservative in mammals.

ROLE OF HS-CRP AND IRISIN IN OBESITY AND TYPE II DIABETES MELLITUS

2021 ◽  
pp. 46-47
Author(s):  
Pankaj Kambale ◽  
Sandip Lambe ◽  
Kanchan Lambe
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Control Group ◽  
Case Group ◽  
Type Ii ◽  
Hs Crp

Background: Overweight and type of II diabetes is emerging as important disease and the prevalence of these diseases is also increasing signicantly. Studies had proposed that irisin is having a role to play in pathophysiology of obesity and other metabolic diseases. The patients who are having type 2 diabetes are found to have higher irisin levels. The study on the association of irisin and hs-CRP with obesity and type 2 diabetes is increasing. Aim: The aim of the present study is to identify the role of irisin and HS-CRP in obesity and type II diabetes mellitus. Material and Methods: This was a community based cross-sectional study which is conducted on the medical OPD visitors of a tertiary care centre. For conducting this study 50 participants ageing between 10-50 years were selected and both male and female participants were included in this research study. In this study 25 patients belong to the case group and 25 patients were of the control group. Results: In the present study the mean of the HS-CRP was found to be 1.45±0.56 for case group and for the control group it was found to be 0.83±0.49. In the present study the mean irisin value for the case group was found to be 8.27±3.21 and for the control group it was found to be 7.47±2.54. Conclusion: In the current study it was found that the hs-CRP and the irisin level of the patients with type 2 diabetes and obesity are higher as compared with the normal individuals. It can be said that both the hs-CRP and the irisin level are positively associated with the obesity and type II diabetes mellitus.

scholarly journals Relationship Between Serum Ferritin Level and Hba1c in Bangladeshi Type 2 Diabetic Patients

2018 ◽  
Vol 9 (1) ◽  
pp. 29-33
Author(s):  
Farhana Khondker ◽  
Manindra Nath Roy ◽  
Purnima Rani Saha ◽  
Rubena Huq ◽  
Rumana Ahmed ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Serum Ferritin ◽  
Pearson Correlation ◽  
Control Group ◽  
Case Group ◽  
Diabetic Patients ◽  
Endocrine Disorders ◽  
Medical College

Background: Diabetes mellitus (DM) type 2 is one of the most common endocrine disorders affecting more than 135 million people in the world. The etiology of the disease is not fully understood, but recently subclinical hemochromatosis has been considered as one of the probable causes of DM. This study was carried out to examine the relationship between serum ferritin as a marker of iron overload with DM and HbA1c.Materials & Method: This study was conducted in the Biochemistry department of Sir Salimullah Medical College, Dhaka; over a period of 18 months from July 2013 to December 2014. In this case control study, 46 patients with type 2 diabetes were taken as case, who were referred to theoutpatient department of "Ibrahim General Hospital & Diabetic care & Educational Center"(DCEC). 46 normal individuals were included as the control group, who were matched with the case group regarding age, sex, BMI and Hb%. Ferritin, hemoglobin, HbA1c and fasting plasma sugar were measured in blood samples. Exclusion criteria included anaemia, or any other disease or drug that could affect ferritin levels.Result: Results were analyzed statistically by Chi-square test, Student's t-test, Pearson correlation coefficient test and Odds ratio.Mean serum ferritin was significantly higher in diabetics than in the control group (197.97±75.99 µgm/L vs. 64.24±27.83 µgm/L, p<0.001). There was significant positive correlation between serum ferritin and HbA1cin diabetic patients (p<0.001). In this study, OR of 11.64 was also found.Conclusion: Serum ferritin is positively correlated with type 2 Diabetes Mellitus. And this may be an important and independent predictor for development of diabetes mellitus.Anwer Khan Modern Medical College Journal Vol. 9, No. 1: Jan 2018, P 29-33

scholarly journals Sugar-Sweetened Beverages, Obesity, Type 2 Diabetes Mellitus, and Cardiovascular Disease Risk

Circulation ◽  
2010 ◽  
Vol 121 (11) ◽  
pp. 1356-1364 ◽  
Author(s):  
Vasanti S. Malik ◽  
Barry M. Popkin ◽  
George A. Bray ◽  
Jean-Pierre Després ◽  
Frank B. Hu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Type 2 Diabetes Mellitus ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Sugar Sweetened Beverages ◽  
Sweetened Beverages

scholarly journals The Increase of Periodontal Tissue in Type 2 Diabetes Mellitus Patients Based on Index CPITN

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
Budiman Budiman
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Periodontal Disease ◽  
Periodontal Pocket ◽  
Control Group ◽  
Case Group ◽  
Diabetic Patients ◽  
Periodontal Tissue ◽  
Pocket Depth

The prevalence of periodontal disease in Indonesia for all age groups has reached 96.58%. Periodontal disease has been identified as a consequence of diabetes mellitus (DM). The purpose of this study is to determine the differences of periodontal tissues in type 2 diabetes and non-diabetic patients based on CPITN index (Community periodontal index of Treatment index). This study employed case control design. The population of the study consisted of 3.544 visits in the Internal Disease Polyclinic of RSUD Cimahi Cibabat in January 2015. The samples for case group were 50 people (diabetes mellitus type 2) and control group were 50 people (non-DM). The sampling technique used accidental sampling. The study was conducted in 2015 by conducting measurement of periodontal pocket depth using CPITN index. The analysis of data was carried out with independent T test. The results show that the average pocket depth based on CPITN index in the case group of type 2 DM (4.26) is greater than control group of patients without DM (3.14). There is different condition on the periodontal tissue in the group of type 2 diabetes (value-p = 0.002 <0.05). The awareness in increasing the oral health protection is done by providing consultation related to blood glucose.

scholarly journals The Patterns of Oral Diseases among Type 2 Diabetes Mellitus Patients Attending at National Healthcare Network (NHN) Mirpur Centre, Dhaka, Bangladesh

2013 ◽  
Vol 3 (2) ◽  
pp. 5-11
Author(s):  
SZ Mahmud ◽  
A Mustakim ◽  
A Taleb
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Alveolar Bone ◽  
Control Group ◽  
Case Group ◽  
Oral Diseases ◽  
National Healthcare ◽  
Healthcare Network

Background: The term “diabetes mellitus” describes a group of disorders characterized by elevated levels of glucose in the blood and abnormalities of carbohydrate, fat and protein metabolism. A number of oral diseases and disorders are associated with diabetes mellitus and, gingivitis and periodontitis have been identified as possible risk factors for poor metabolic control in subjects with diabetes. Objective: To assess oral diseases in type 2 diabetes mellitus patients and controls who attended at National Healthcare Network (NHN), Mirpur Centre, Dhaka, Bangladesh. Materials & Methods: A total of 100 subjects - 47 diabetics and 53 non-diabetics fulfilled the eligibility criteria were selected consecutively. Pretested semi-structured interviewer administered questionnaire and check list were utilized to assess the main objective of the study. Cross tabulations and associations were found out by using Chi-square Test  Statistical Package for the Social Sciences was used for data analysis. Results: The cases were relatively older than the controls with mean age of the subjects in case group being significantly higher than that in the control group (p < 0.001), but the groups were not statistically different in terms of sex (p = 0.194). More than two-thirds (68.1%) of the cases and 52.8% of the controls exhibited burning mouth syndrome (p = 0.120). Candidiasis and dental caries were associated, more than in case control group (p = 0.020 and p < 0.001 respectively). Gingivitis was found significantly higher in case group compared to control group (78.7% vs. 37.7%, p < 0.001). In the case group, nearly half (48.9%) had periodontitis, 29.8% alveolar bone loss and 27.7% collagen metabolism, as opposed to none in the control group (p < 0.001). Conclusion: Oral diseases are multi-factorial and the factors responsible for these diseases are preventable. Dentists must be familiar with techniques to diagnose, treat and prevent oral diseases in patients with diabetes. DOI: http://dx.doi.org/10.3329/bjdre.v3i2.16602 Bangladesh Journal of Dental Research & Education Vol.3(2) 2013: 5-11

ESTIMATION OF SERUM FERRITIN LEVELS IN TYPE 2 DIABETIC PATIENTS AND ITS RELATION WITH HbA1C LEVEL.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Shah Namrata Vinubhai ◽  
Pardeep Agarwal ◽  
Bushra Fiza ◽  
Ramkishan Jat
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Serum Ferritin ◽  
Inflammatory Marker ◽  
Control Group ◽  
Diabetic Patients ◽  
Positive Correlation

Background: Serum ferritin is known as an index for body iron stores also as an inflammatory marker and it is influenced by several disease. We were looking for a correlation between HbA1c and S. Ferritin in type 2 DM. Methodology: The present study a total of 150 participants were enrolled of which 100 were confirmed cases of Type 2 Diabetes Mellitus and rest 50 age and sex matched healthy subjects constituted the control group. All were screened for HbA1c, Fasting blood sugar, Post prandial blood sugar and S.Ferritin. Results: A highly significant variation and positive correlation was observed with respect to S.Ferritin and HbA1c levels. Mean S.Ferritin was high in the subgroup with poor glycemic control. Conclusion: The fasting, post prandial sugar levels, HbA1c and S.Ferritin were significantly higher in the diabetic subjects. This study shows a positive correlation between HbA1c and S. Ferritin levels. So we can conclude that in diabetic patients S. Ferritin may serve as an independent marker of poor glycemic and metabolic control. Keywords: Serum ferritin, Type 2 Diabetes Mellitus, HbA1c.

Rheumatoid Factor in Type 2 Male Diabetes Mellitus Patients in a Tertiary Care Hospital of Bangladesh

2018 ◽  
Vol 4 (2) ◽  
pp. 58-62
Author(s):  
Roksana Yeasmin ◽  
MA Muttalib ◽  
Kazi Nazneen Sultana ◽  
Nizamul Hoque Bhuiyan ◽  
Md Jamil Hasan Karami ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Rheumatoid Factor ◽  
Serum Uric Acid ◽  
Control Group ◽  
Healthy Male ◽  
Male Patients

Background: Type 2 diabetes mellitus is a chronic disease characterized by relative or absolute deficiency of insulin, resulting in glucose intolerance.Objectives: The present study was planned to see the associations of serum uric acid with positive Rheumatoid factor in type 2 male diabetes mellitus patients. Methodology: This case control study was carried out at the department of Biochemistry at Ibrahim Medical College, Dhaka, Bangladesh. The duration of the study was from June 2015 to June 2016 for a period of one year. In this present study, male patients with type 2 diabetes mellitus were taken as case group and age and sex matched healthy male were taken as control group. Rheumatoid factor was measured from the blood of all case and control group respondents. Others blood para meters were also measured for the correlation with the diabetes mellitus patients.Results: In this present study, 110 male patients presented with type 2 diabetes mellitus were recruited as case and age and sex matched healthy male were recruited as control. More rheumatoid factor positive in type 2 DM male patients with the uric acid range between 6.5 to 9.5 mg/dL. The number of patients was 5 out of total 9 rheumatoid factor positive cases. In this study serum uric acid was significantly correlated with rheumatoid factor in type 2 male diabetic patients. Rheumatoid factor positive cases were taking insulin among 9 and it was statistically significantly associated (p<0.001). Conclusion: In this study serum uric acid is significantly associated with positive rheumatoid factor in type 2 male diabetic patients.Journal of Current and Advance Medical Research 2017;4(2):58-62

Impact of Physical Activity on the Incidence of Vascular Diseases in Adults with Type 2 Diabetes Mellitus

2019 ◽  
Vol 8 ◽  
pp. 1549
Author(s):  
Babak Pezeshki ◽  
Ehsan Bahramali ◽  
Amir Ansari ◽  
Aliasghar Karimi ◽  
Mojtaba Frajam ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Vascular Function ◽  
Vascular Diseases ◽  
Major Complication ◽  
Control Group ◽  
Case Group ◽  
Vascular Events ◽  
The Relationship

Background: Diabetes mellitus (DM) is a common metabolic disease worldwide and has many complications. The vascular events are the major complication of DM that have an important effect on mortality and disability. The physical activity (PA) enhances the vascular function by several pathways. The aim of this study was to evaluation of the relationship between PA and vascular diseases in patients with DM.Materials and Methods: This research was performed as the case-control study that was extracted from a prospective epidemiological research study in Iran (PERSIAN). The patients with type 2 DM more than six months defined as case group and the non-DM subjects in control group with ratio 1:2, and both groups were matched in the term of age and sex. The MET score was used to evaluate the level of PA and blood glucose, lipid profile, body mass index, overweight, dyslipidemia, glomerular filtration rate, myocardial infarction (MI), unstable angina, and stroke.Results: Overall, 1242 patients with DM were extracted, and 2484 non-diabetic subjects were investigated. In the case group, 355(28.6 %) and 887(71.4%) were men and women, respectively, the and 710 (28.6%) men and 1774(71.4%) women in control group. The mean MET score was 30 and 40.97 in the DM and non-DM groups, respectively (P˂0.001). The frequency of MI, stroke, and cardiac ischemia were 44 (3.5%), 37 (3%), and 267 (21.5%), respectively in DM group, and 54 (2.2%), 43 (1.7%), and 389 (15.7%), respectively in non-DM group.Conclusion: The incidence of vascular events associated with PA level in patients with DM and adherence to regular PA reduce the vascular events and DM complications. [GMJ.2019;inpress:e1549]

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