scholarly journals Simulation application for express analysis of bolted joint of plates made of laminated composite material for strength taking into account technological factors

2021 ◽  
Author(s):  
Yurii Dyfuchyn ◽  
Serhii Babiienko ◽  
Konstantin Rudakov
Keyword(s):  
Laminated Composite ◽  
Polymeric Composite ◽  
Bolted Joint ◽  
Structural Element ◽  
Bolted Connection ◽  
Tightening Force ◽  
Technological Factors ◽  
Modern Computer ◽  
Express Analysis ◽  
Selection Of

The structural element in the form of bolted connection (BC) of plates from polymeric composite materials (PCM) is not supported in modern computer CAD systems in a convenient form for the express analysis. Therefore, research aimed at creating appropriate tools in the form of additional programs is relevant. The application BJE (Bolted Joint Emulations) is presented at the paper. It was created by the authors on the basis of available results of simulation calculations of BC of plates made of layered PCM. Selection of corresponding analytical solutions, the revealed functional dependences, approximations were used. The feature of this development is taking into account influence of the main technological factors: tightening force, side gaps, stuck of layers in the PCM, others.

scholarly journals Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation

mBio ◽  
2018 ◽  
Vol 9 (5) ◽  
Author(s):  
Mariia Novikova ◽  
Lucas J. Adams ◽  
Juan Fontana ◽  
Anna T. Gres ◽  
Muthukumar Balasubramaniam ◽  
...  
Keyword(s):  
Virus Assembly ◽  
Critical Role ◽  
Replication Cycle ◽  
Structural Defects ◽  
Fold Axis ◽  
Structural Element ◽  
Particle Assembly ◽  
Compensatory Mutations ◽  
Hiv 1 ◽  
Selection Of

ABSTRACTLate in the HIV-1 replication cycle, the viral structural protein Gag is targeted to virus assembly sites at the plasma membrane of infected cells. The capsid (CA) domain of Gag plays a critical role in the formation of the hexameric Gag lattice in the immature virion, and, during particle release, CA is cleaved from the Gag precursor by the viral protease and forms the conical core of the mature virion. A highly conserved Pro-Pro-Ile-Pro (PPIP) motif (CA residues 122 to 125) [PPIP(122–125)] in a loop connecting CA helices 6 and 7 resides at a 3-fold axis formed by neighboring hexamers in the immature Gag lattice. In this study, we characterized the role of this PPIP(122–125) loop in HIV-1 assembly and maturation. While mutations P123A and P125A were relatively well tolerated, mutation of P122 and I124 significantly impaired virus release, caused Gag processing defects, and abolished infectivity. X-ray crystallography indicated that the P122A and I124A mutations induce subtle changes in the structure of the mature CA lattice which were permissive forin vitroassembly of CA tubes. Transmission electron microscopy and cryo-electron tomography demonstrated that the P122A and I124A mutations induce severe structural defects in the immature Gag lattice and abrogate conical core formation. Propagation of the P122A and I124A mutants in T-cell lines led to the selection of compensatory mutations within CA. Our findings demonstrate that the CA PPIP(122–125) loop comprises a structural element critical for the formation of the immature Gag lattice.IMPORTANCECapsid (CA) plays multiple roles in the HIV-1 replication cycle. CA-CA domain interactions are responsible for multimerization of the Gag polyprotein at virus assembly sites, and in the mature virion, CA monomers assemble into a conical core that encapsidates the viral RNA genome. Multiple CA regions that contribute to the assembly and release of HIV-1 particles have been mapped and investigated. Here, we identified and characterized a Pro-rich loop in CA that is important for the formation of the immature Gag lattice. Changes in this region disrupt viral production and abrogate the formation of infectious, mature virions. Propagation of the mutants in culture led to the selection of second-site compensatory mutations within CA. These results expand our knowledge of the assembly and maturation steps in the viral replication cycle and may be relevant for development of antiviral drugs targeting CA.

scholarly journals Investigation on the Optimum Tightening Force of Bolted Joint in Torque Control Method

1973 ◽  
Vol 39 (462) ◽  
pp. 748-752
Author(s):  
Kaoru HONGO ◽  
Isamu YOSHIMOTO ◽  
Gendai ETO ◽  
Tsutomu SASAKI
Keyword(s):  
Control Method ◽  
Torque Control ◽  
Bolted Joint ◽  
Tightening Force

Strategic analysis of the competitiveness of the enterprise

2021 ◽  
pp. 35-46
Author(s):  
Yuliia Grynchuk ◽  
Andrii Muzychenko ◽  
Kseniia Prykhod’ko
Keyword(s):  
Price Policy ◽  
Strategic Analysis ◽  
Competitive Advantages ◽  
Macroeconomic Factors ◽  
Modern Computer ◽  
Study Results ◽  
Essential Components ◽  
Selection Of

The purpose of the article is to develop a methodology of strategic analysis of enterprise competitiveness. The methodological basis of the research is the use of general scientific methods: the method of analysis and synthesis, theoretical generalization and comparison, and the means of modern computer technology for data visualization. The scientific novelty of the received results consists of developing a logical and linguistic methodology of competitiveness analysis in the long term. The article is devoted to the development of strategic analysis of the competitiveness of the enterprise. Relevance of research is caused by enterprises management in the modern markets that use innovations of products or technologies, constantly face competition, and according to its condition, should make decisions on strategic development in conformity with the country’s development market inquiries the society. Thus, the problem is not only for new companies but also for those that already function in the market and carry out planning of economic activity to become the market leader, not to lose leadership, to keep the positions. The given methodology can be used by any enterprise irrespective of the type of activity, form of ownership, or strategic goals. Conclusions. According to the study results, the methodology of strategic analysis, which is based on the study of potential internal development of the enterprise, taking into account the influence of external factors, which include macroeconomic factors of influence and market conditions. The basic approaches to the analysis of the competitiveness of the enterprise of foreign and domestic researchers are investigated in the article. The essential components of competitive advantages, which include price and non-price factors, are considered. Peculiarities of carrying out the analysis of the competitiveness of the enterprise after Porter are defined. The methodology of competitiveness analysis in the long term is developed. The main components of the strategic analysis are the estimation of activity scale in a long-term prospect, determination of strategic aims of the company, determination of aims of market coverage, selection of strategy type, selection of basic subjects of influence on competitive advantages, assessment of future relations with suppliers and buyers, assessment of cost price level, assessment of the quality of products and services and unique properties of products, formation of internal price policy. Key words: strategy, strategic analysis, competitiveness, competitive advantages.

A New Approach for Determining Bolt Load of Eccentric Bolted Joints

2014 ◽  
Vol 668-669 ◽  
pp. 115-118
Author(s):  
Xi Wang Wang ◽  
Xiao Yang Li ◽  
Xiao Guang Wang ◽  
Lin Lin Zhang
Keyword(s):  
Fatigue Loading ◽  
Bolted Joints ◽  
Bolted Joint ◽  
Bolted Connection ◽  
New Approach ◽  
Nonlinear Variation ◽  
Linear Elastic ◽  
Proposed Model ◽  
Service Load ◽  
Interface Contact

Bolt load in a bolted connection directly influence the safety of a design in regard to both static and fatigue loading as well as in the prevention of separation in the connection. When the separating force is applied off the bolt center, although the materials for the bolted joint remain in the linear elastic range, the interface contact area between the clamped plates is sensitive to both the magnitude and the location of the separating force. This often causes nonlinear variation of the bolt load, the deformation etc. An analytical model is proposed to obtain the expression for the nonlinear bolt load under a separating service load. Finite element modeling is used for evaluating the accuracy of the proposed model.

Buckling of Perforated Plates Repaired with Composite Patches

2008 ◽  
Vol 385-387 ◽  
pp. 377-380 ◽  
Author(s):  
Jalil Rezaeepazhand ◽  
H. Sabori
Keyword(s):  
Laminated Composite ◽  
Quantitative Measure ◽  
Structural Elements ◽  
Structural Element ◽  
Perforated Plates ◽  
Advanced Composite ◽  
Numerical Studies ◽  
Load Carrying ◽  
Circular Cutout ◽  
Relative Change

Performance level and life span of existing structural elements can be increased by repair and strengthening of these structural elements using advanced composite materials.The performance of damaged metallic plates reinforced with fiber-reinforced polymer composite materials (composite patch) are presented in this study. A square aluminum plate with a central circular cutout is considered as a damaged structural element. Numerical studies using commercial finite element code were conducted to investigate the effects of variation in patch geometries and lamination parameters on buckling responses of repaired plates. The varying laminate parameters such as, fiber angles and stacking sequences are considered in this study. A quantitative measure for the effectiveness of the composite patches is taken to be the relative change in buckling loads of the reinforced plates compare to those of the perfect one. The results presented herein indicated that, for buckling response of a repaired metallic plate with central cutout, a set of laminated composite patches with different shape and stacking sequences can be found which improve load carrying capacity of damaged plates.

The need to strengthen the physical fitness of the special operations military forces and the Main Intelligence Directorate of the Russian Federation

2020 ◽  
pp. 153-165
Author(s):  
Yurii Y. Korablev ◽  
Igor Y. Pugachev ◽  
Esedulla M. Osmanov ◽  
Sergey Y. Dutov
Keyword(s):  
Physical Fitness ◽  
Special Operations ◽  
Modern Computer ◽  
Special Groups ◽  
Massive Scale ◽  
Special Operations Forces ◽  
The Russian Federation ◽  
High Selection ◽  
High Level ◽  
Selection Of

We consider the provisions of the need to strengthen the physical fitness of the special operations forces and the Main Intelligence Directorate, caused by the tendency to add to the special groups lineup people who possess high-level skills in modern computer technologies. In the special operations forces units and the Main Intelligence Directorate, there is a high selection of employees in terms of physical condition and perfect mastery of the electronic equipment skills, while at the same time, the equipment is constantly being improved. On a massive scale, objectively team cannot equally possess the skills of working with computer technology, only particularly unique specialists are able to perfectly work in this direction. The life of these military personnel in the process of warfare must be preserved first of all. This causes a tendency to increase the level of physical fitness of the personnel of these special forces, especially when exercising the load against the backdrop of complex fatigue.

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