Elicitor Application Influences the Phytochemical Profile of Salacia reticulata with the Formation of New Novel Metabolites of      Medicinal Value

Justicia gendarussa Burm .f. (family Acanthaceae) which is also known as willow-leaves and commonly known as Nili-Nirgundi, it is very commonly found nearby to China and its availability is very common in larger parts of India and Andaman islands. Traditionally it is used to treat various sorts of disorders such as wound healing, anti-inflammatory, anti-oxidant, antiproliferative, anti-arthritic etc. Justicia gendarussa is one of the crucial herbs which has been used in the Ayurveda. Majorly leaves parts of the plant shows the pharmacological activity but the root of the plant Justicia gendarussa is also have the important medicinal values. A large variety of pharmacologically active constituents i.e., alkaloids, flavonoids, saponin, carbohydrates, steroids, triterpenoids, carotenoids, aminoacids, tannins, phenolics, coumarines and anthaquinones are also present in this plant and they makes the plant pharmacologically important. The activity of the plant is also dependent on the solvent which is used for the extraction the various vital chemical constituents. The different- different parts of the plants having the different medicinal values also differ in the chemical values. This review is not only focused on the essential phytochemical constituents which is available in the plant but it also explains their necessary medicinal value to shows the essential biological action and phytopharmacological actions of various parts of the plant.

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Investigation of Phytochemical Profile and Antibacterial Potential of Prosopis glandulosa

SINDH UNIVERSITY RESEARCH JOURNAL -SCIENCE SERIES ◽

10.26692/surj/2019.09.613 ◽

2019 ◽

Vol 51 (03) ◽

pp. 459--464

Author(s):

S. QAIMKHANI ◽

M. A. MOGHAL ◽

A. H. MOGHAL ◽

M. Q. SAMEJO, ◽

A. A. BHUTTO ◽

...

Keyword(s):

Prosopis Glandulosa ◽

Phytochemical Profile ◽

Antibacterial Potential

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Faculty Opinions recommendation of Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13679.471174 ◽

2006 ◽

Author(s):

Brent Bauer

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Black Cohosh ◽

Liquid Chromatography Mass Spectrometry ◽

Selected Ion Monitoring ◽

Chromatography Mass Spectrometry ◽

Phytochemical Profile

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Therapeutic Potential of Citronella Essential Oil: A Review

Current Drug Discovery Technologies ◽

10.2174/1570163815666180718095041 ◽

2019 ◽

Vol 16 (4) ◽

pp. 330-339 ◽

Cited By ~ 9

Author(s):

Ruchi Sharma ◽

Rekha Rao ◽

Sunil Kumar ◽

Sheefali Mahant ◽

Sarita Khatkar

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Environmental Protection Agency ◽

Therapeutic Potential ◽

Biological Properties ◽

Toxic Encephalopathy ◽

Practical Applications ◽

Insect Repellents ◽

Citronella Oil ◽

Medicinal Value

Mosquito-borne diseases such as malaria, filariasis, chikunguniya, yellow fever, dengue and Japanese encephalitis are the major cause of remarkable morbidity and mortality in livestock and humans worldwide. Since ancient times, aromatic plants are used for their medicinal value. Essential oils derived from these plants may be used as effective alternatives/adjuvants in pharmaceuticals, biomedical, cosmetic, food, veterinary and agriculture applications. These oils have also gained popularity and interest for prevention and treatment of various disorders. However, several reports on adverse effects including skin eruption, contact artricaria or toxic encephalopathy in children are available for synthetic repellent in the literature. Thus, natural insect repellents like essential oils have been explored recently as an alternative. One such essential oil studied widely, is citronella oil, extracted mainly from Cymbopogon nardus. This essential oil has exhibited good efficacy against mosquitoes. It is a mixture of components including citronellal, citronellol, geraniol as major constituents contributing to various activities (antimicrobial, anthelmintic, antioxidant, anticonvulsant antitrypanosomal and wound healing), besides mosquito repellent action. Citronella essential oil is registered in US EPA (Environmental protection agency) as insect repellent due to its high efficacy, low toxicity and customer satisfaction. However, poor stability in the presence of air and high temperature limits its practical applications. Since specific knowledge on properties and chemical composition of oil is fundamental for its effective application, the present review compiles and discusses biological properties of citronella oil. It also sheds light on various formulations and applications of this essential oil.

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Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520619666190416101622 ◽

2019 ◽

Vol 19 (13) ◽

pp. 1651-1657

Author(s):

Zouhaier Bouallagui ◽

Asma Mahmoudi ◽

Amina Maalej ◽

Fatma Hadrich ◽

Hiroko Isoda ◽

...

Keyword(s):

Antioxidant Activity ◽

Hepg2 Cells ◽

Cytotoxic Activities ◽

Phenolic Composition ◽

Olive Leaves ◽

Total Polyphenols ◽

Cytotoxic Effects ◽

Antioxidant Profile ◽

Phytochemical Profile ◽

Mcf 7

Aim: This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from Chemlali cultivar. Materials and Methods: The Phenolic composition of olive leaves extracts, the antioxidant activity and the cytotoxic effects against MCF-7 and HepG2 cells were determined. Results: Olive leaves extracts showed relevant total polyphenols contents. Oleuropein was the major detected phenolic compound reaching a concentration of 16.9 mg/ml. The antioxidant potential of the studied extracts varied from 23.7 to 46.5mM Trolox equivalents as revealed by DPPH and ABTS assays. Cytotoxicity experiments showed similar trends for both HepG2 and MCF-7 cells with the infusion extract being the most active. Conclusion: This study denotes that olive leaves may have great potential as endless bioresource of valuable bioactive compounds which may have a wide application.

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Chemical Composition and in-vitro antimicrobial screening of leaf essential oil of Plectranthus gerardianus Benth., and isolation of the major constituent of oil

The Natural Products Journal ◽

10.2174/2210315510999200731183701 ◽

2020 ◽

Vol 10 ◽

Author(s):

Navadha Bhatt ◽

Navabha Joshi ◽

Kapil Ghai ◽

Om Prakash

Keyword(s):

Antimicrobial Activity ◽

Essential Oil ◽

Major Constituent ◽

In Vitro Antimicrobial Activity ◽

Gram Positive Bacteria ◽

Medicinal Value ◽

Leaf Essential Oil ◽

Plant Families ◽

Total Oil

Background: The Lamiaceae (Labiatae) is one of the most diverse and widespread plant families’ in terms of ethno medicine and its medicinal value is based on the volatile oils concentration. This family is important for flavour, fragrance and medicinal properties. Manyplants belonging to this family have indigenous value. Method: The essential oil of Plectranthus gerardianusBenth. (Lamiaceae), was analysed by GC and GC-MS analysis, while the major component was isolated and conformed by NMR spectroscopy. Result: The oil was found to be rich in oxygenated monoterpenes, which contribute around 62% of the total oil. The major components identified were fenchone (22.90%) and carvenone oxide (16.75%), besides other mono and sesquiterpenoids. The in-vitro antimicrobial activity of essential oil was tested against three gram negative bacteria viz. Pasteurellamultocida, Escherichia coli, and Salmonella enterica, two gram positive bacteria viz. Staphylococcus aureus and Bacillus subtilis and two fungi viz. Candida albicans and Aspergillusflavus. The antimicrobial activity of the oil was also compared to the antimicrobial activity of leaf essential oil of another Himalayan plant viz. Nepetacoerulescens. Conclusion: The oil showed in-vitro antimicrobial activity against all the microbial strains and can lessen the ever-growing demand of potentially hazardous antibiotics for treatment.

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Investigation of Nutritional Contents, Antioxidant and Immunostimulatory Activities of Aqueous Extract from Laguncularia racemosa Leaves

The Natural Products Journal ◽

10.2174/2210315510666200108105217 ◽

2020 ◽

Vol 10 ◽

Author(s):

Dayane Kelly Dias do Nascimento Santos ◽

Cristiane Moutinho Lagos de Melo ◽

Elivânia Maria da Silva ◽

Vanessa Silva de Almeida ◽

Iranildo José da Cruz Filho ◽

...

Keyword(s):

Antioxidant Activity ◽

Aqueous Extract ◽

Antioxidant Activities ◽

Folk Medicine ◽

Proliferation Index ◽

Laguncularia Racemosa ◽

High Concentration ◽

Popular Medicine ◽

Biological Tests ◽

Phytochemical Profile

Background: One of the four most incident species in mangrove is the Laguncularia racemosa, plant widely used in popular medicine against inflammation and fever. Objective: Here, L. racemosa was investigated in relation to their phytochemical profile, antioxidant activity, citotoxicity, antimicrobial and immunostimulatory effect. Method: Aqueous extract was obtained from leaves of plant, its phytochemical profile was investigated through UPLC method, the antioxidant assays performed were TAA, DPPH, ABTS, nitrite and lipid peroxidation assay. Antimicrobial assays were made using standard strains. For all biological tests were used mice splenocytes and from these cell cultures were measured cytotoxicity, proliferation index and cytokines production. Results: Laguncularia racemosa leaves showed the presence of ions, proteins, carbohydrates, vitamins and high concentration of phenolic compounds. Antioxidant activities were promoted by aqueous extract, especially in DPPH and NO assays. Extract in 6 µg/mL did not induce significant cell death, stimulated the cell proliferation and the IL-4 production. Moreover, decreases of proinflammatory cytokines IFN-γ, TNF-α and IL-6 were found. Conclusion: The presence of essential nutrients, significant antioxidant activity and immune stimulation confirm the use of this plant in folk medicine against inflammation.

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