scholarly journals Gambaran Populasi Golongan Darah Subgroup A (A1, A2) di PMI Kulon Progo

Biosfera ◽  
2017 ◽  
Vol 34 (1) ◽  
pp. 47
Author(s):  
Hieronymus Rayi Prasetya ◽  
Bambang Heru Budianto ◽  
Hernayanti Hernayanti
Keyword(s):  
Genetic Variation ◽  
Blood Group ◽  
Sampling Technique ◽  
Red Cross ◽  
Cross Sectional ◽  
Dolichos Biflorus ◽  
Blood Group A ◽  
Group A ◽  
Transfusion Reactions

Subgroup A1 and A2 are the most important in the blood group A. Subgroup A1 has the A antigen more than A2 subgroup, the A2 subgroup can cause misidentification of blood group due to poor A antigen and genetic variation possessed. Misidentification of the blood group will increase the risk of transfusion reactions. This research aims to describe the A1 and A2 subgroup population in Kulon Progo district. This study was conducted with a cross sectional sampling technique. The sample in this study were taken from donors of blood group A in Kulon Progo Red Cross. Identification of A1 and A2 subgroup is done by using lectin (Dolichos biflorus extract). The result of the examination of 53 samples showed that 96,2% was A1 subgroup and 3,8% was A2 subgroup.Key words : Subgroup A1, Subgroup A2, Population, Kulon Progo

scholarly journals Immunochemical studies on blood groups LXII. Fractionation of hog and human A, H, and AH blood group active substance on insoluble immunoadsorbents of Dolichos and Lotus lectins.

1976 ◽  
Vol 143 (2) ◽  
pp. 422-436 ◽  
Author(s):  
M E Pereira ◽  
E A Kabat
Keyword(s):  
Blood Group ◽  
Optical Rotation ◽  
Gastric Mucin ◽  
Specific Optical Rotation ◽  
Dolichos Biflorus ◽  
Blood Group A ◽  
Analytical Properties ◽  
Group Substance ◽  
Group A

The purified lectins from Lotus tetragonolobus and Dolichos biflorus were coupled to Sepharose 2B to make insoluble adsorbents for purification and fractionation of blood group A and H active glycoproteins. With both adsorbents, hog gastric mucin A + H blood substance (HGM), purified by phenol-ethanol precipitation, yielded fractions showing only A, only H, or AH activities. The AH fraction was obtained when the adsorbent column was overloaded with HGM and its A and H specificities seem to be carried on the same molecules since they were not separable by chromatography on either column. However A and H specificities of blood group substance from the stomach of a presumably heterozygous individual hog were both on the same molecules as they too could not be fractionated on either column. Analytical properties of the isolated fractions were generally similar to those of the unfractionated material, the purfied A substances had a higher galactosamine/fucose ratio than did the H substances. Although the original A + H showed very little specific optical rotation, the separated A and H substances rotated positively and negatively, respectively. The lectin-Sepharose adsorbents have also proven useful in isolating A or H substances directly from the crude commercial hog gastric mucin. Blood group A2 substance from a human ovarian cyst yielded two fractions on the Lotus-Sepharose column; the effluent did not interact with the Lotus lectin but precipitated the Ulex and Dolichos lectins and anti-A, and appears to contain type 1 H determinants. The other fraction reacted with Lotus and Ulex lectin as well as with Dolichos and anti-A.

scholarly journals Association of Pre-hypertension with blood groups in young population.

2019 ◽  
Vol 26 (11) ◽  
pp. 1820-1824
Author(s):  
Benash Altaf ◽  
Shireen Jawed ◽  
Fakiha Behram ◽  
Zeeshan Ali Khan ◽  
Shakeela Naz
Keyword(s):  
Blood Group ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
P Value ◽  
Continuous Variables ◽  
Cross Sectional ◽  
Blood Group A ◽  
Significant Difference ◽  
Group A

Objectives: Pakistan has highest mortality rate due to hypertension and its complications. Hypertension is a squealed of Pre- hypertension which is believed to start at adolescent and continue to adulthood. Association of blood group with hypertension is evident but still hypothesized. This study aims to find the frequency of prehypertension and its association with blood group. Study Design: Cross sectional study. Setting:  Aziz Fatimah Medical and Dental College, Faisalabad. Period: 15 March’18 to 15 Sep’18. Material and Methods:  It was comprised of in comprised of 100 MBBS students. Demographic data including age, weight, height, waist and hip circumference, and BMI was determined. Blood group was determined with help of conventional slide method. Blood pressure was measured by auscultatory method. Data was analyzed by using SPSS 21. Continuous variables are given in mean and standard deviation. Categorical data was given in frequency and percentages. P value≤ 0.05 is taken as significant. Results: Out of 100 participants most common blood group was group ‘O’ (43%) followed by B (35 %) and AB (13%) and A (9%).36% of total population was pre-hypertensive and 64% were normotensive. Prehypertension is most commonly found in blood group ‘A’ (77%) followed by blood group ‘O’ (46.5%). Significant difference was found in means of SBP (p value= 0.001*) and DBP (p value= 0.000*) among the various blood groups. Conclusion: Most common blood group in studied population was ‘O’ although hypertension was most commonly observed in blood group A followed by ‘O’.

scholarly journals DIFFERENT BLOOD GROUPS

2016 ◽  
Vol 23 (08) ◽  
pp. 1001-1004
Author(s):  
Naila Parveen ◽  
Javeria Rehman ◽  
Syed Hafeezul Hassan ◽  
Zoya Hassan ◽  
Madiha Rehman
Keyword(s):  
Body Mass Index ◽  
Medical Students ◽  
Blood Group ◽  
Body Mass ◽  
Blood Groups ◽  
Blood Type ◽  
P Value ◽  
Cross Sectional ◽  
Blood Group A ◽  
Group A

Objectives: To find out the association of body mass index with different bloodgroups in medical students. Background: Increased body mass index leads to obesity and is aprominent risk factor for hypertension and diabetes. Blood groups are known to be associatedwith various diseases and recent studies have shown that a particular blood group with thehighest body mass index appeared to be more susceptible to predisposition to hypertension.Study Design: Cross-sectional study. Setting: Liaquat National Medical College, Karachi.Period: June 2015 to September 2015. Methodology: 181 medical students with 85 malesand 96 females and age ranging from 18-22 years. Weight and height of each student wasmeasured using the standard stadiometer and blood groups were determined using the antisera.Results: Mean age of the participants was 19.92 ± 1.10 years. Blood group “O” wasfound to be most prevalent (39.2%) while blood group “AB” was found to be the least (8.3%).Mean BMI of subjects with blood group A, B, AB and O were found to be 24.3 ± 5.04, 22.6 ±3.59, 23.0 ± 2.91 and 23.7 ± 4.20 kg/m2 respectively. The highest BMI was found in subjectswith blood group “A” 24.3 ± 5.04 kg/m2 and lowest in blood group “AB” 23.0 ± 2.91kg/m2. TheRhesus-D positive and male students had greater body mass index 23.6 ± 3.56 than females23.2 ± 3.44. Comparison of overall mean BMI values among different blood groups showedsignificant difference with p-value < 0.001. Conclusion: Blood group “A” and Rhesus-D positivesubjects especially males were found to be the high risk blood type with predisposition tomorbidity associated with increased body mass index.

scholarly journals Frequency of blood group sub-type in patients with ischemic stroke at Nishtar Hospital Multan.

2019 ◽  
Vol 26 (08) ◽  
pp. 1333-1338
Author(s):  
Muhammad Tahir ◽  
Gohar Ali ◽  
Ali Ismail
Keyword(s):  
Ischemic Stroke ◽  
Blood Group ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
Cross Sectional ◽  
Blood Group A ◽  
Increased Risk ◽  
Study Results ◽  
Group A ◽  
Group B

The objective of this study was to determine the blood groups among the patients presenting with ischemic stroke either AB blood group or O blood group is more common (frequent) among these patients irrespective of other known factors responsible for stroke. Study Design: Descriptive, Cross-sectional study. Setting: Department of Medicine, Nishtar Hospital Multan. Period: January 2015 to August 2015. Materials & Methods: We included total 292 patients (40-70 years of age), with ischemic stroke documented on CT scan brain of both gender (male and female). Blood sample of these patients were sent to the central laboratory of Nishtar hospital for blood group determination using standard techniques. Results: Mean age was 56.26 ± 8.28 years. Out of the 292 patients, 163 (55.82%) were male and 129 (44.18%). Frequency of blood group A, B, AB and O in patients with ischemic stroke was found to be 114 patients having blood group A (39.04%), 53 patients having blood group B (18.15%), 26 patients having blood group AB (8.90%) and 99 patients having blood group O (33.90%) respectively. Conclusion: Our study results concluded that there is an association between ABO blood groups and ischemic stroke, irrespective of other risk factors. Our study results have observed that individuals belonging to non-O blood groups (A, B, or AB) are at an increased risk of ischemic stroke as compared to O blood group carriers however we did not control possible impact of confounders such as diabetes, hypertension and dyslipidemia etc. Many studies proved that persons with AB blood groups are at increased of atherosclerosis but no study showed that these persons have increased risk of ischemic stroke or not.

scholarly journals Prevalence and association of malaria with ABO blood group and hemoglobin levels in individuals visiting Mekaneeyesus Primary Hospital, Estie District, northwest Ethiopia: A cross-sectional study

2020 ◽  
Author(s):  
Balaynesh Tazebew ◽  
Abaineh Munshea Abitew ◽  
Endalkachew Nibret
Keyword(s):  
Logistic Regression ◽  
Blood Group ◽  
Cross Sectional Study ◽  
Abo Blood Group ◽  
Insect Vector ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Group A ◽  
Primary Hospital ◽  
Group A

Abstract Background Malaria continues to be a major health problem in developing sub-Saharan countries including Ethiopia. Malaria is a complex disease and its local characteristics are determined by a variety of geographical, environmental, insect vector, host, and parasite factors.Methods A hospital based cross-sectional study was conducted to determine the prevalence of malaria and its possible association with hemoglobin level and ABO blood group among individuals attending Mekaneeyesus Primary Hospital, Estie District, northwestern Ethiopia. Socio-demographic variables and relevant data were collected from 390 randomly selected individuals through structured questionnaire. Then, thick and thin smears were prepared from finger pricked blood samples, stained, and examined microscopically for detection and identification of malaria parasites. ABO blood group and hemoglobin levels of the same subjects were also determined. The data generated were entered into a computer and analyzed for descriptive and logistic regression models using SPSS version 23.0. Variables with p-value < 0.05 in multivariable logistic regression were considered as explanatory variables.Results The overall prevalence of malaria was 8.5%; Plasmodium vivax (5.6%) was the most predominant, followed by P. falciparum (2.3%), and mixed infection of the two species (0.5%). In multivariate logistic regression analysis, being male (AOR = 3.48), under-five years of age (AOR = 72.84), rural residence (AOR = 2.64), and failing to use bed net (AOR =4.65) were significantly associated with the risk of malaria infection. Most (14.6%) of malaria positives cases were among individuals with blood group “A”, while the least number of cases were among subjects with blood group “O”. Individuals with blood group “A” were about four times more likelihood of getting malaria as compared to individuals with blood group “O” (AOR= 3.74). The prevalence of anemia was 23% and significantly associated with malaria (p<0.05).Conclusions Malaria in the study area is still higher than the average prevalence at country level. Therefore special attention should be given to the prevention and control strategies with the objective of increasing the awareness of local community towards malaria.

scholarly journals The Impact of ABO Blood Grouping on COVID-19 Vulnerability and Seriousness: A Retrospective Cross-Sectional Controlled Study among the Arab Community

2021 ◽  
Vol 18 (1) ◽  
pp. 276
Author(s):  
Nagla A. El-Shitany ◽  
Manal El-Hamamsy ◽  
Ahlam A. Alahmadi ◽  
Basma G. Eid ◽  
Thikryat Neamatallah ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Blood Group ◽  
Artificial Respiration ◽  
Blood Groups ◽  
The Other ◽  
Controlled Study ◽  
Cross Sectional ◽  
Blood Group A ◽  
Group A ◽  
The Impact

Background and Objectives: Studies have noted that some ABO blood types are more susceptible to COVID-19 virus infection. This study aimed to further confirm the relationship between different blood groups on the vulnerability, symptoms, cure period, and severity among COVID-19 recovered patients. Subjects and Methods: This cross-sectional study approached the participants from the Arab community via social media (mainly Facebook and WhatsApp). The data were collected through two Google Form questionnaires, one for COVID-19 recovered patients (COVID-19 group, n = 726), and the other for the healthy people (Control group, n = 707). Results: The subjects with blood group O were the least likely to be infected with the COVID-19 virus, while those with blood group A were not likely to be the most susceptible. There were significant differences among different ABO blood groups regarding the distribution of oxygen saturation percentage, myalgia, and recovery time after COVID-19 infection (p < 0.01, 0.01, and 0.05, respectively). The blood group A showed the highest percentage of patients who experienced an oxygen saturation range of 90–100%, whereas the blood group O showed the highest percentage of patients who experienced an oxygen saturation range of 70–80%. The blood group A showed the lowest percentage of patients who required artificial respiration, whereas the blood group O showed the highest percentage of patients who required artificial respiration. The blood group B showed the lowest percentage of patients who experienced myalgia and exhibited the lowest percentage of patients who needed 3 weeks or more to recover. Conclusion: The people of blood group O may be the least likely to be infected with COVID-19, however, they may be the more in need of treatment in hospital and artificial respiration compared to the other blood groups.

scholarly journals ABO-RH blood group and risk of covid-19 in a moroccan population

2020 ◽  
Author(s):  
Mourad Belaouni ◽  
Elhoucine Malki ◽  
Rabii El Bahraouy ◽  
Bouchra El Maliki ◽  
Mohammed Er-Rami ◽  
...  
Keyword(s):  
Blood Group ◽  
Comparison Group ◽  
Blood Groups ◽  
Military Hospital ◽  
Control Group ◽  
Rt Pcr ◽  
Cross Sectional ◽  
Moroccan Population ◽  
Blood Group A ◽  
Group A

AbstractIntroductionGiven the rapid spread, significant morbidity and mortality associated with COVID-19, there has been scientific interest in obtaining data detailing the factors influencing the risk of COVID-19 infection. The aim of this study was to reveal a possible association between the ABO-RH system and the risk of COVID-19 in the Moroccan population.Materials and methodsThis is an analytical cross-sectional study. It was carried out on 1094 patients for the diagnosis of Covid-19 by Rt-PCR at the Moulay Ismaïl military hospital in the province of Meknes. All Rt-PCR negative individuals were used as a comparison group.ResultsAmong the 1094 individuals who were diagnosed, RT-PCR for detection of SARS-CoV-2 was positive for 242 individuals. Comparison of the proportions of blood groups of the two groups showed that the proportion of blood group A in patients with COVID-19 was significantly higher than in people in the comparison group (P = 0.007), while the proportion of blood group O in patients with COVID-19 was significantly lower than in people in the control group (P = 0.017). Comparison of the Rh blood groups of the two groups did not find a significant association (P = 0.608).ConclusionAs demonstrated by several previous studies, we concluded that blood group A was associated with a higher risk of acquiring COVID-19. Equally, the O blood group was associated with a lower risk of infection.

scholarly journals Dolichos biflorus agglutinin (DBA) reacts selectively with mast cells in human connective tissues.

1988 ◽  
Vol 36 (10) ◽  
pp. 1231-1237 ◽  
Author(s):  
M Hormia ◽  
A L Kariniemi ◽  
L Laitinen ◽  
I Virtanen
Keyword(s):  
Endothelial Cells ◽  
Mast Cells ◽  
Blood Group ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Connective Tissues ◽  
Dolichos Biflorus ◽  
Dolichos Biflorus Agglutinin ◽  
Blood Group A ◽  
Group A

Dolichos biflorus agglutinin (DBA) binds to N-acetyl-D-galactosamine (GalNAc) residues in glycoconjugates and agglutinates erythrocytes carrying blood group antigen A. In cryostat sections of various tissues from blood group-specified humans, fluorochrome-coupled DBA bound preferentially to fusiform connective tissue cells and to certain epithelial cells. The connective tissue cells were identified as mast cells by their typical metachromasia in consecutive staining with toluidine blue. Double labeling with DBA and conjugated avidin revealed two distinct populations of mast cells. In several tissues the DBA-reactive cells likewise displayed uniform avidin reactivity. In intestinal mucosa, however, morphologically distinct DBA-binding mast cells were found, which were labeled with the avidin conjugates only in specially fixed paraffin sections. DBA did not bind to vascular endothelial cells, which could be identified by double staining with antibodies to factor VIII-related antigen. Labeling with Helix pomatia agglutinin (HPA), another blood group A-reactive lectin, resulted in distinct blood group-dependent fluorescence of the endothelia. Sophora japonica agglutinin (SJA), a blood group B-reactive lectin, labeled vascular endothelial cells in tissues from blood group A, AB, and B donors. HPA and SJA reacted with small mast cells in the gastrointestinal mucosa but failed to label large mast cells in any of the tissues. These results indicate that the blood group reactivity of lectins, as determined by erythroagglutination, is not necessarily consistent with their reactivity with blood group determinants in tissue sections. Moreover, DBA conjugates appear to be a reliable probe for detection of mast cells in various human connective tissues.

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