scholarly journals Comprehensive Etiological and Epidemiological Study on Acute Respiratory Infections in Children: Providing Evidence for the Prevention and Control of Childhood Pneumonia in the Philippines

2018 ◽  
Vol 13 (4) ◽  
pp. 740-750 ◽  
Author(s):  
Raita Tamaki ◽  
Veronica L. Tallo ◽  
Alvin G. Tan ◽  
Mark Donald C. Reñosa ◽  
Portia P. Alday ◽  
...  
Keyword(s):  
Risk Factors ◽  
Epidemiological Study ◽  
Prevention And Control ◽  
Respiratory Infections ◽  
The Philippines ◽  
Acute Respiratory Infections ◽  
Community Settings ◽  
Research Project ◽  
Childhood Pneumonia ◽  
And Control

Childhood pneumonia has been the leading cause of morbidity and mortality for decades. Although substantial progress in the understanding of risk factors and etiology of pneumonia has been made, childhood pneumonia remains the major cause of death in children, accounting for 900,000 of the estimated 6.3 million child deaths worldwide in 2013. More than 90% of all episodes of clinical childhood pneumonia worldwide occur in low and middle-income countries. More effective and feasible interventions need to be developed and made widely available for such countries, including the Philippines. Comprehensive research, including etiological and epidemiological studies for assessments of risk factors and thereby, intervention studies to reduce the impact of childhood pneumonia are required in hospital settings, as well as community settings, consistently. A research project entitled “comprehensive etiological and epidemiological study on acute respiratory infections in children: providing evidence for the prevention and control of childhood pneumonia, the Philippines” was conducted under SATREPS (Science and Technology Research Partnership for Sustainable Development), which is a funding scheme to promote international joint research focusing on global issues. This project was implemented in four sentinel hospitals, with some community settings, in the Philippines between April 2011 and March 2017, incorporating five sub-components: etiological study, disease burden study, risk factor analysis, intervention study, and its evaluation. In this paper, we introduce the research project of SATREPS focusing on the methodologies, progress, and obtained evidence.

scholarly journals Etiological and epidemiological features of acute respiratory infections in China

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Zhong-Jie Li ◽  
Hai-Yang Zhang ◽  
Li-Li Ren ◽  
Qing-Bin Lu ◽  
Xiang Ren ◽  
...  
Keyword(s):  
Respiratory Infections ◽  
Bacterial Pathogens ◽  
Acute Respiratory Tract Infection ◽  
School Age Children ◽  
Positive Interactions ◽  
Acute Respiratory Infections ◽  
Epidemiological Features ◽  
Point Analysis ◽  
Syncytial Virus ◽  
And Control

AbstractNationwide prospective surveillance of all-age patients with acute respiratory infections was conducted in China between 2009‒2019. Here we report the etiological and epidemiological features of the 231,107 eligible patients enrolled in this analysis. Children <5 years old and school-age children have the highest viral positivity rate (46.9%) and bacterial positivity rate (30.9%). Influenza virus, respiratory syncytial virus and human rhinovirus are the three leading viral pathogens with proportions of 28.5%, 16.8% and 16.7%, and Streptococcus pneumoniae, Mycoplasma pneumoniae and Klebsiella pneumoniae are the three leading bacterial pathogens (29.9%, 18.6% and 15.8%). Negative interactions between viruses and positive interactions between viral and bacterial pathogens are common. A Join-Point analysis reveals the age-specific positivity rate and how this varied for individual pathogens. These data indicate that differential priorities for diagnosis, prevention and control should be highlighted in terms of acute respiratory tract infection patients’ demography, geographic locations and season of illness in China.

scholarly journals Risk factors of dengue fever in an urban area in Vietnam: a case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Thang Nguyen-Tien ◽  
Duy Cuong Do ◽  
Xuan Luat Le ◽  
Thi Hai Dinh ◽  
Mats Lindeborg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dengue Fever ◽  
Prevention And Control ◽  
Case Control Study ◽  
Case Control ◽  
Younger Adults ◽  
The Mean ◽  
Dengue Prevention ◽  
And Control ◽  
Control Study

Abstract Background Dengue is a mosquito-borne flavivirus present in many metropolitan cities of tropical countries. Methods During and after the dengue season (September 2018 to January 2019), we conducted a case-control study in order to determine the risk factors for dengue fever in Hanoi city, Vietnam. 98 dengue patients and 99 patients with other acute infections, such as Hepatitis B virus infection, were recruited at Department of Infectious Disease of Bach Mai national hospital in Hanoi. Patients were interviewed using a structured questionnaire covering demographic, housing, environmental factors and knowledge, attitude, and practice on dengue prevention and control. Univariate analysis and multivariable logistic regression were used to determine the risk factors of dengue status. Results The mean score of knowledge items and practice items was only 7.9 out of total 19 points and 3.9 out of total 17 points, respectively. While the mean score of attitude items was 4.8 out of total 6 points. Multivariable logistic regression indicated that older patients had lesser risk of getting dengue infection as compared to younger adults aged 16–30, and patients living in peri-urban districts were less likely to suffer of dengue fever than patients living in central urban districts (OR = 0.31; 95% CI 0.13–0.75). This study could not find any association with occupation, water storage habit, knowledge, attitude, or practice on dengue prevention. Conclusions All patients had a relatively low level of knowledge and practice on dengue prevention and control. However, the attitude of the participants was good. We found that age group and living district were the risk factors correlated with the dengue status. Communication programs on raising dengue awareness should be repeated all year round and target particular groups of adolescents, younger adults, landlords and migrants from other provinces to improve their knowledge and encourage them to implement preventive measures against dengue fever.

Components of a risk assessment tool for prevention and control of bovine respiratory disease in preweaned dairy calves

2020 ◽  
pp. 1-7
Author(s):  
Sharif S. Aly ◽  
Betsy M. Karle ◽  
Deniece R. Williams ◽  
Gabriele U. Maier ◽  
Sasha Dubrovsky
Keyword(s):  
Risk Factors ◽  
Risk Assessment ◽  
Risk Factor ◽  
Respiratory Disease ◽  
Scoring System ◽  
Prevention And Control ◽  
Assessment Tool ◽  
Bovine Respiratory Disease ◽  
And Control ◽  
Management Changes

Abstract Bovine respiratory disease (BRD) is the leading natural cause of death in US beef and dairy cattle, causing the annual loss of more than 1 million animals and financial losses in excess of $700 million. The multiple etiologies of BRD and its complex web of risk factors necessitate a herd-specific intervention plan for its prevention and control on dairies. Hence, a risk assessment is an important tool that producers and veterinarians can utilize for a comprehensive assessment of the management and host factors that predispose calves to BRD. The current study identifies the steps taken to develop the first BRD risk assessment tool and its components, namely the BRD risk factor questionnaire, the BRD scoring system, and a herd-specific BRD control and prevention plan. The risk factor questionnaire was designed to inquire on aspects of calf-rearing including management practices that affect calf health generally, and BRD specifically. The risk scores associated with each risk factor investigated in the questionnaire were estimated based on data from two observational studies. Producers can also estimate the prevalence of BRD in their calf herds using a smart phone or tablet application that facilitates selection of a true random sample of calves for scoring using the California BRD scoring system. Based on the risk factors identified, producers and herd veterinarians can then decide the management changes needed to mitigate the calf herd's risk for BRD. A follow-up risk assessment after a duration of time sufficient for exposure of a new cohort of calves to the management changes introduced in response to the risk assessment is recommended to monitor the prevalence of BRD.

scholarly journals Tackling antimicrobial resistance in the community

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Tonkie-Crine ◽  
L Abel ◽  
O Van Hecke ◽  
K Wang ◽  
C Butler
Keyword(s):  
Antibiotic Resistance ◽  
Community Care ◽  
Respiratory Infections ◽  
Antibiotic Prescription ◽  
Future Research ◽  
Antibiotic Prescribing ◽  
Acute Respiratory Infections ◽  
Community Settings ◽  
The Public ◽  
Need Support

Abstract Antibiotic prescription is a major driver of antibiotic resistance. The majority of antibiotic prescribing occurs in community care settings, often for respiratory infections. A substantial proportion of prescriptions are issued not according to guidelines, particularly for acute respiratory infections which can be self-limiting. Prescribers in these settings need support to prescribe antibiotics more prudently. Patients and the public also need support to manage infections which are self-limiting. This presentation presents a summary of how antimicrobial stewardship (AMS) activities are being used in community settings. Firstly, types of community-level interventions are discussed, including those aimed at clinicians, patients and the public. Next, we assess interventions based on their effectiveness at reducing antibiotic prescriptions or use and their cost-effectiveness. Finally, we discuss directions for future research and consider how the research to date could influence policy.

scholarly journals Risk factors and biofilm formation analyses of hospital-acquired infection of Candida pelliculosa in a neonatal intensive care unit

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhijie Zhang ◽  
Yu Cao ◽  
Yanjian Li ◽  
Xufang Chen ◽  
Chen Ding ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Biofilm Formation ◽  
Prevention And Control ◽  
Neonatal Intensive Care ◽  
Infection Prevention ◽  
Infection Prevention And Control ◽  
Anti Fungal ◽  
Hospital Acquired ◽  
And Control

Abstract Background Candida pelliculosa is an ecological fungal species that can cause infections in immunocompromised individuals. Numerous studies globally have shown that C. pelliculosa infects neonates. An outbreak recently occurred in our neonatal intensive care unit; therefore, we aimed to evaluate the risk factors in this hospital-acquired fungal infection. Methods We performed a case-control study, analysing the potential risk factors for neonatal infections of C. pelliculosa so that infection prevention and control could be implemented in our units. Isolated strains were tested for drug resistance and biofilm formation, important factors for fungal transmission that give rise to hospital-acquired infections. Results The use of three or more broad-spectrum antimicrobials or long hospital stays were associated with higher likelihoods of infection with C. pelliculosa. The fungus was not identified on the hands of healthcare workers or in the environment. All fungal isolates were susceptible to anti-fungal medications, and after anti-fungal treatment, all infected patients recovered. Strict infection prevention and control procedures efficiently suppressed infection transmission. Intact adhesin-encoding genes, shown by genome analysis, indicated possible routes for fungal transmission. Conclusions The use of three or more broad-spectrum antimicrobials or a lengthy hospital stay is theoretically associated with the risk of infection with C. pelliculosa. Strains that we isolated are susceptible to anti-fungal medications, and these were eliminated by treating all patients with an antifungal. Transmission is likely via adhesion to the cell surface and biofilm formation.

scholarly journals Risk Factors for Acute Respiratory Infections (ARI) Among Under-five Children in Bangladesh

2008 ◽  
Vol 1 (1) ◽  
pp. 72-81 ◽  
Author(s):  
Kazi Md. Abul Kalam Azad
Keyword(s):  
Risk Factors ◽  
Vitamin A ◽  
Adolescent Mothers ◽  
Home Visiting ◽  
Respiratory Infections ◽  
Vitamin A Deficiency ◽  
Significant Risk ◽  
Childhood Mortality ◽  
Acute Respiratory Infections ◽  
Mortality And Morbidity

Acute respiratory infection (ARI) is a major cause of childhood mortality and morbidity in Bangladesh. The aim of this study is to identify the significant risk factors for ARI in children less than five years of age. The data in this study comes from Bangladesh Demographic and Health Survey (BDHS) 2004. In this study, a child was considered as having experienced ARI if she or he had cough in the last two weeks preceding the survey with any one of the three symptoms of short but rapid breathing, difficulty of breathing or labored inspiration. Logistic regression was used on various independent variables to find the risk factors. Results showed that child's age, sex, body weight and Vitamin A deficiency were correlated with prevalence of ARI. Additionally mother's characteristics like age, malnutrition, education level, and family's socio-economic status were found to be associated. Recommendations include more specific knowledge of ARI to adolescent mothers from the lowest wealth quintile. A community service which could include home visiting for health education, supplementation of vitamin A, and advice would be an advantage if provided for poor or teenaged pregnant women. This in turn would reduce low birth weight incidence, and subsequently reduce incidence of ARI among these children.Keywords: Acute respiratory infections (ARI); Risk factors; Infant; Child under 5 years; Bangladesh.© 2009 JSR Publications. ISSN: 2070-0237(Print); 2037-0245 (Online). All rights reserved.DOI: 10.3329/jsr.v1i1.1055

scholarly journals Evaluation of malaria risk factors prevention and control program in Kulon Progo Regency

2017 ◽  
Vol 33 (12) ◽  
pp. 565
Author(s):  
Husni Husni ◽  
Th. B Rahayujati ◽  
S Supargiyono
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Health Center ◽  
Prevention And Control ◽  
Larval Fish ◽  
Control Program ◽  
Malaria Risk ◽  
District Health ◽  
And Control ◽  
Malaria Risk Factors

Evaluation of malaria risk factors prevention and control program in Kulon Progo RegencyPurposeThe purpose of this research was to evaluate the program of prevention and control of malaria risk factors in Kulon Progo District in 2016 based on system approach.MethodThis research was evaluation program used mixed methods (sequential explanatory design). Data collected from 7 public health center of active focus malaria and district health office. Respondents were program managers and head of public health center, district program managers, head of control and eradication of communicable diseases, and head of district health offices. The instruments used structured questionnaires and in-depth interview guides. Quantitative data analysis was descriptive and qualitative data used Miles and Huberman model.Results Most of the availability of human resources, funds, facilities, materials, and methods already meet implementation needs except entomologists, allocation of funds activities other than IRS, time of the implementation of larval fish deployment. Most of the processes that started from the planning, implementation, monitoring, and evaluation have gone well except for planning other than IRS, preparation vector control without entomology database, implementation of environmental management, larviciding, and larval fish deployment. Coverage of LLINs, coverage of IRS, control of LLINs efficacy, and test of vector resistance have met the target, except coverage of larviciding and larval fish deployment was not available.ConclusionPrevention and control program of malaria risk factors has implemented but wasn’t based on entomological data. District health offices should recruit entomologist to support vector control activities.

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