scholarly journals Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

2019 ◽  
Vol 15 (4) ◽  
pp. 450-466 ◽  
Author(s):  
Yu. A. Balanova ◽  
S. A. Shalnova ◽  
A. E. Imaeva ◽  
А. V. Kapustina ◽  
G. A. Muromtseva ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Russian Federation ◽  
Ischemic Heart ◽  
Medical Community ◽  
Epidemiological Methods ◽  
Control Group ◽  
The Russian Federation ◽  
And Control

Participants of the study ESSE-RF-2 and co-authors: Moscow: Konstantinov V. V., Pokrovskaya M.S., Efimova I.A., Sivakova O.V.; Krasnodar: Alekseenko S.N., Gubarev S.V.; Оmsk: Livzan M.A., Grishechkina I.A., Rozhkova M.Yu.; Republic of Karelia: Vezikova N.N., Skopec I. S.; Ryazan: Filippov E.V., Dobrynina N.V., Nikulina N.N., Pereverzeva K.G., Moseychuk K.A.Aim. Evaluate the prevalence, awareness, treatment, and control of hypertension among people aged 25-64 examined in 4 regions of the Russian Federation. Material and methods. Study materials were the representative selections of non-organized male (n=3000) and female (n=3714) inhabitants of aged 25-64 from 4 regions of the Russian Federation (Krasnodar region, Omsk region, Ryazan region, the Republic of Karelia), response rate>80%. Systematic stratified multilevel random election was formed with locality criteria (Kisch method). All the participants were interviewed using the standard questionnaire. The universal epidemiological methods and evaluation criteria were used. The study was approved by the local ethics Committee of National research center for preventive medicine. Participants signed informed consent. Hypertension was defined as an average systolic blood pressure (SBP)≥140 mmHg and/or average diastolic blood pressure (DBP)≥90 mmHg and/or antihypertensive therapy (AHT). The efficacy of treatment was the achievement of the target BP. Control group – patients with BP<140/90 mmHg. Results. Mean SBP and DBP were 128.7±0,3 mmHg and 82.8±0.1 mmHg, respectively, higher BP was detected among male (p<0,001). The prevalence of hypertension was 44.2% that was higher among males than females (49.1% vs 39.9%, р˂0.0005), the highest hypertension frequency was in the Ryazan region. The awareness of hypertension was higher among females than in males 76.8% vs 69.4%. There were more persons with hypertension grade 1 among those, who were not aware of the hypertension. Medications were taken by 65.5% of females and 41.8% of males.Angiotensin-converting enzyme inhibitors were received by 49.9% of patients, angiotensin II receptor antagonists by 30.9%, beta blockers – 29.5%, diuretics – 22.7%, calcium antagonists – 15.7%, centrally acting drugs – 3.3%, others – 0.2%. The lack of AHT intake was negatively associated with age, ischemic heart disease, urban life and hypo-HDL especially among males. Heart rate >80 per min in females increased by 1.7 times the probability of absence of AHT. The prevalence of effectively treated was 49.7% of the participants with hypertension. The associations between ineffective treatment and abdominal obesity, ischemic heart disease (males), age, rural type of settlement, obesity (females) were found. Only 24.9% of patients had control of the hypertension.Conclusion. The prevalence of hypertension in Russian Federation remains high. An important task of the medical community is to identify the disease at an earlier stage of its development, before the appearance of complications. This approach can reduce the period from the onset of high blood pressure to a visit to the doctor.

scholarly journals The Impact of the Introduction of Clinical Recommendations on Cardiology in the USA and Russia Federetionon Mortality from Ischemic Heart Diseas

2018 ◽  
Vol 17 (4) ◽  
pp. 30-37
Author(s):  
A. A. Gerasimov
Keyword(s):  
United States ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Russian Federation ◽  
Clinical Guidelines ◽  
The United States ◽  
Ischemic Heart ◽  
The Russian Federation ◽  
The Impact

1 million 824 thousand people died in the Russian Federation in 2017, including 457 thousand from ischemic heart disease (IHD). IHD caused more than a quarter of deaths in Russia. Goal. The article analyzes the impact of implementation of clinical guidelines in cardiology in medical practice in the United States and the Russian Federation on the dynamics of mortality from ischemic heart disease and its outcomes in different age groups. Results. The results showed that the implementation of clinical guidelines (CG) increased the rate of mortality reduction from coronary heart diseases in Russia and the United States, which may indicate a positive impact CG on the quality of medical care. Conclusions. A higher level of mortality from coronary heart disease in Russia compared to the United States may be due to less commitment of doctors to the principles of therapy and diagnosis of various forms of coronary heart disease, set out in clinical guidelines.

VIII Congress of Therapists of the Russian Federation (Nizhny Novgorod, October 1-2, 1998)

1999 ◽  
Vol 80 (2) ◽  
pp. 151-153
Author(s):  
I. A. Latfullin
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Arterial Hypertension ◽  
Russian Federation ◽  
Ischemic Heart ◽  
Medical Society ◽  
Metabolic Factors ◽  
Russian Scientific ◽  
The Russian Federation

The VIII Congress was opened by the chairman of the Russian Scientific Medical Society of Physicians, Acad. RAMS, prof. A.P. Golikov.Prof. E.P. Kamyshova et al. (N. Novgorod) was devoted to the role of hemodynamic and metabolic factors in arterial hypertension (AH) and ischemic heart disease.

Effects of substitution dietary guidelines targeted at prevention of ischemic heart disease on dietary intake and risk factors in middle-aged Danish adults: The DIPI randomized controlled trial

2020 ◽  
pp. 1-35
Author(s):  
Johanne Louise Gotfredsen ◽  
Camilla Hoppe ◽  
Rikke Andersen ◽  
Elisabeth Wreford Andersen ◽  
Rikard Landberg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Dietary Intake ◽  
Controlled Trial ◽  
Dietary Guidelines ◽  
Ischemic Heart ◽  
Control Group ◽  
Dietary Changes

Abstract The objective was to investigate the effects of substitution (SUB) dietary guidelines (DG) targeted at prevention of ischemic heart disease (IHD) on dietary intake and IHD risk factors in Danish adults with minimum one self-assessed IHD risk factor. A 6-month single-blinded parallel randomised controlled trial with a follow-up at month 12 included 219 subjects (median age 51 years, 59% female, 73 % overweight or obese) randomised into a SUB DG, an official (OFF) DG or a control group following their habitual diet (HAB). Participants in the DG intervention groups received bi-weekly reminders of their DG and recipes for dishes and the HAB group received a greeting. Dietary intake and fasting blood, anthropometric, and blood pressure measurements were obtained at baseline, month 6 and month 12. Linear regression analyses were applied. At month 6, when compared with the HAB, the SUB had a greater impact on the extent of dietary changes with increased intake of whole grains, dietary fibre, and low fibre vegetables compared with the OFF DG and both DG groups had similar decreased percentage of energy (E%) intake from saturated fatty acids. The extent of dietary changes were similar at month 12. No overall significant changes from baseline were found in blood pressure (BP), anthropometrics and IHD risk markers. In conclusion, both SUB and OFF DG resulted in cardioprotective dietary changes. However, neither the SUB nor the OFF DG resulted in any overall effects on the selected intermediate risk factors for IHD.

scholarly journals Role of Duke treadmill score in the diagnosis of ischemic heart disease in women

2015 ◽  
Vol 53 (2) ◽  
pp. 146-152
Author(s):  
Alexandra Dǎdârlat ◽  
D. Zdrenghea ◽  
Dana Pop
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Ischemic Heart Disease ◽  
Cardiovascular Risk Factors ◽  
High Blood Pressure ◽  
Ischemic Heart ◽  
Risk Category ◽  
Duke Treadmill Score

Abstract Ischemic heart disease is underdiagnosed in women due to atypical symptomatology as well as to the lower specificity of several paraclinical tests, such as exercise stress testing. The aim of the study was to ascertain whether the Duke treadmill score (DTS) could be an efficient parameter in the diagnosis of ischemic heart disease in women. Material and method. 105 patients were enrolled in the study, 45.71% women with average age ranged between 20 and 70 years, investigated in the Rehabilitation Hospital, Cardiology-Departament, Cluj-Napoca, Romania. All the patients were clinically assessed as concerns the presence of cardiovascular risk factors, and they underwent electrocardiographic, echocardiographic and treadmill stress tests. DST was calculated according to the formula: exercise time – 5 x (ST deviation expressed in mm–4 x Angina Index). Results. DTS was lower in women as compared to men: 2.54±5.36 vs. 6±4.69, p=0.0006. 54.28% of the patients were ranged with a low DTS risk category, whereas 45.71% belonged to a moderate and high risk category. DTS was significantly lower in women than in men with high blood pressure (2.03±4.8 vs. 5.8±4.28), hypercholesterolemia (1.14±4.51 vs. 6.24±4.13), diabetes mellitus (1.83 ± 3.73 vs. 6.13±4.8), and obesity (2.42±5.35 vs. 5.81±4.64). By analyzing the presence of cardiovascular risk factors only in women, we noticed that only those with high blood pressure (2.03±4.89 vs. 8.13 ±7.85) and hypercholesterolemia (2.31±4.76 vs. 3.89±5.95) had a statistically significant low DTS (p<0.05). In conclusion, our research, which showed differences in DTS between women and men, raises concerns about the early diagnosis of ischemic heart disease in women.

Polymorphisms in the Genes for Coagulation Factors II, V, and VII in Patients With Ischemic Heart Disease

1999 ◽  
Vol 123 (12) ◽  
pp. 1230-1235
Author(s):  
Yue Jin Feng ◽  
Andrew Draghi ◽  
Douglas R. Linfert ◽  
Alan H. B. Wu ◽  
Gregory J. Tsongalis
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Coagulation Factors ◽  
The United States ◽  
Ischemic Heart ◽  
Factor Vii ◽  
Control Groups ◽  
Sequence Of Events ◽  
Increased Risk ◽  
And Control

Abstract Background.—Cardiovascular disease remains the leading cause of mortality in the United States, accounting for approximately 33% of all deaths in this country. Of these deaths, most are due to acute myocardial infarctions (AMIs), which are associated with thrombotic coronary artery obstruction and/or occlusion. These events could potentially be due to alterations in genes coding for coagulation factors. Several polymorphisms have been described in the factor II, V, and VII genes, which may predispose one to increased risk for ischemic heart disease (IHD). Objective.—To determine if mutations in 3 coagulation factor genes could predispose an individual to increased risk for arterial thrombosis as a mechanism for developing unstable angina (UA) or AMI. Methods.—We examined 125 hospitalized patients (mean age, 53 ± 6 years, 79 men and 46 women), including 32 with AMI, 68 with UA, and 25 noncardiac controls, for a genetic predisposition for increased risk of IHD. EDTA-anticoagulated whole blood was collected at the time of hospital admission. DNA was extracted, and the polymorphisms were detected by polymerase chain reaction amplification of these genes with subsequent restriction enzyme digestion and gel electrophoresis. Results.—Our results showed that 3 (9.4%), 3 (4.4%), and 1 (4%) individuals were heterozygous for prothrombin G20210A and 3 (9.4%), 5 (7.4%), and 1 (4%) individuals were heterozygous for factor V Leiden in the AMI, UA, and control groups, respectively. The following genotype frequencies for the factor VII R353Q polymorphism were identified: 25 (78.1%), 56 (82.4%), and 18 (72%) with RR and 7 (21.9%), 12 (17.6%), and 7 (28%) with RQ in the AMI, UA, and control groups, respectively. No QQ homozygotes were identified. For the HVR4 size polymorphism, the following genotypes were identified: 3 (9.4%), 4 (5.9%), and 5 (20%) individuals with H7H7; 11 (34.4%), 33 (48.5%), and 12 (48%) with H6H7; and 18 (56.2%), 31 (45.6%), and 8 (32%) with H6H6 genotypes in the AMI, UA, and control groups, respectively. There were no H7H5 and H6H5 genotypes found in this study. Conclusions.—Although the frequency differences of these polymorphisms in patients with AMI and UA were not statistically significant from those in controls, several trends are consistent with what has been reported in the literature. Although any of these or other undefined genetic abnormalities may result in IHD, it is possible that phenotypic predisposition to IHD initially presents as UA. A larger population study addressing the significance of these polymorphisms in the sequence of events that lead to IHD, including cases of UA, is warranted.

Intra-operative blood pressure control by prostaglandin E1 in patients with hypertension and ischemic heart disease

1993 ◽  
Vol 7 (2) ◽  
pp. 173-183 ◽  
Author(s):  
Sumio Hoka ◽  
◽  
Junichi Yoshitake ◽  
Kenjiro Dan ◽  
Yutaka Goto ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Blood Pressure Control ◽  
Prostaglandin E1 ◽  
Pressure Control ◽  
Ischemic Heart

scholarly journals Blood Pressure, Risk of Ischemic Cerebrovascular and Ischemic Heart Disease, and Longevity in α1-Antitrypsin Deficiency

Circulation ◽  
2003 ◽  
Vol 107 (5) ◽  
pp. 747-752 ◽  
Author(s):  
Morten Dahl ◽  
Anne Tybjærg-Hansen ◽  
Henrik Sillesen ◽  
Gorm Jensen ◽  
Rolf Steffensen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Antitrypsin Deficiency

scholarly journals Evaluation of Ischemic Heart Disease in the Young Population of Georgia

2021 ◽  
Vol 17 (18) ◽  
Author(s):  
Gogishvili Giorgi
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Young People ◽  
Ischemic Heart Disease ◽  
Night Shift ◽  
Young Patients ◽  
Female Gender ◽  
Ischemic Heart ◽  
Control Group ◽  
Ischemic Disease

Objective: Study of risk factors (RF) for ischemic heart disease (IHD) in young people is a significant problem in cardiology. Aims: Study and prognosis of ischemic heart disease in Georgian population under 45 years of age. Methods: The study included 107 young patients with coronary heart disease (from 18 to 44 years old), who were treated in the cardiology department of the St. John the Merciful Private Clinic. The average age was (34.68 ± 6.2) years. The control group consisted of 199 healthy volunteers without cardiovascular diseases at the age from 18 to 44 years, the average age was (35.9 ± 5.2) years. In all patients, traditional risk factors were assessed. Results: Regression analysis has shown that it increases the risk of ischemic heart disease: living in the city - OR=6.90(95%CI:1.28-37.18); sleep disturbance - OR=45.62(95%CI:3.52-590.64); obesity -OR=24.56(95%CI:4.14-145.66); hypertension - OR=40.76(95%CI:8.07-205.92); excess intake of saturated fats - OR=79.94(95%CI:10.93-584.43); night shift - OR=39.01(95%CI:3.75-405.75); early detection of ischemic disease in grade I-II relatives - OR=44.22(95%CI:8.07-242.17); decrease - female gender - OR=0.14 (95%CI:0.03-0.70) and married - OR=0.01(95%CI:0.00-0.08); Conclusion: The ability to predict the risk of developing IHD in young people on the basis of traditional RFs, most of which are modifiable, as well as the study of "new" RFs opens up new perspectives in the formation of a strategic approach to the management of young patients in the presence of high risk.

Sign in / Sign up

Export Citation Format

Share Document