scholarly journals Demam Berdarah Dengue di Perdesaan

2012 ◽  
Vol 7 (3) ◽  
pp. 120
Author(s):  
Erna Kusumawardani ◽  
Umar Fahmi Achmadi

Berbeda dengan beberapa negara, laporan kejadian kasus demam berdarah dengue (DBD) di perdesaan Indonesia belum banyak dilaporkan. Penelitian ini bertujuan untuk memberikan gambaran kejadian DBD di perdesaan di wilayah perbatasan Kabupaten Bogor dan Kabupaten Lebak, Jawa Barat. Penelitian ini menggunakan desain studi kasus seri dengan sampel seluruh penderita DBD yang tercatat di puskesmas pada periode bulan Januari 2011 sampai April 2012. Hasil penelitian menemukan 18 kasus DBD dan 4 kasus kematian (case fatality rate, CFR = 22%). Sebagian besar kasus berjenis kelamin laki-laki (58,3%), berusia ³ 15 tahun (58,3%), tidak bekerja/ibu rumah tangga (50%), melakukan mobilitas (66,7%), mempunyai pengetahuan yang baik (66,7%), berperilaku kurang baik (83,3%), dan mempunyai tempat penampungan air (100%). Lima dari 12 kasus DBD (41,7%) diduga merupakan kasus lokal. Dari empat puskesmas (57,1%) yang melakukan kegiatan penyelidikan epidemiologi DBD terindikasi bahwa kemungkinan besar telah terjadi transmisi DBD di wilayah perdesaan daerah perbatasan Kabupaten Bogor dan Kabupaten Lebak.Kata kunci: Demam berdarah dengue, perdesaan, transmisiAbstract Dengue hemorrhagic fever (DHF) has long been reported as disease affecting predominantly among urban populations. However, several recent studies suggest that DHF has spread into rural area. This study aims to describe disease occurrence of DHF in border rural areas of Bogor – Lebak. The study design is case series. The sample of this study was all patients with confirmed DHF admitted to public health centers between January 2011 and April 2012. The study was conducted in April to May 2012. The results showed that there were 19 DHF cases and four out of 18 cases died (case fatality rate, CFR was 22%). Out of 12 eligible respondents, most of them were male (58,3%), aged ³ 15 years (58,3%), unemployed/housewife (50%), conducting mobility (66,7%), having good knowledge (66,7%), behave poorly (83,3%), and having water containers (100%). Five of 12 DHF cases (41,7%) were suspected as local cases. Four primary health centers (57,1%) were able to perform PE DBD (DHF Epidemiological Investigation). These results indicate that the transmission of DHF in border rural areas of Bogor – Lebak, most likely has occurred.Key words: Dengue hemorrhagic fever, rural, transmission

Author(s):  
Sawai Singh Rathore ◽  
Ade Harrison Manju ◽  
Qingqing Wen ◽  
Manush Sondhi ◽  
Reshma Pydi ◽  
...  

Background: Crimean-Congo hemorrhagic fever (CCHF) is a fatal acute tick-borne viral infection and a substantial emerging global public health threat. This illness has a high case fatality rate of up to 40%. The liver is one of the important target organs of the CCHF virus. Objective: The aim of this meta-analysis to evaluate the correlation between CCHF  and liver injury and draw more generalized inferences about the abnormal serum markers of liver injury such as alanine aminotransferase (ALT), aspartate aminotransferase (AST) in CCHF patients. Methods: A literature search was accomplished for published eligible articles with MEDLINE/PubMed and Embase databases. All eligible observational studies and case series were included from around the world. The inclusion criteria were articles describing liver injury biomarkers AST and ALT amongst patients diagnosed with CCHF. Results: Data from 18 studies, consisting of 1238 patients with CCHF  were included in this meta-analysis. The overall pooled prevalence of at least one raised liver injury biomarker was 77.95% (95% CI, I2 = 88.50%, p < 0.0001). Similarly, pooled prevalence of elevated AST and ALT was 85.92% (95% CI, I2 = 85.27%,  p < 0.0001) and 64.30% (95% CI, I2 = 88.32%,  p < 0.0001) respectively.  Both Egger and Begg-Mazumdar’s tests detected no apparent publication bias in all three meta-analyses(p > 0.05).  Conclusion: These elevated liver injury biomarkers have been identified as significant prognostic factors. Hence, Physicians must recognize and continuously monitor these biomarkers, since these aid early stratification of prognosis and the prevention of severe outcomes in infection with such a high case fatality rate.


2020 ◽  
Vol 8 (1) ◽  
pp. 35
Author(s):  
Dewi Putri Dayani

Background: Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus which spreads more widely and the morbidity rate increases every year in East Java Province. DHF transmitting vector is widespread in residential areas and in public places, population density, population mobility, increasing urbanization. Purpose: This study aims to describe the number of cases, Incidence Rate (IR), Case Fatality Rate (CFR), and the peak incidence of Dengue Hemorrhagic Fever in East Java Province in 2015-2017. Method: This study is a descriptive approach study with a population that is all East Java residents who are at risk of suffering from dengue. This study uses a total population technique that involves all DHF cases recorded in the East Java Provincial Health Profile for 2015-2017. The data used are secondary data obtained from the Health Profile of East Java Province in 2015-2017, namely the number of DHF cases, gender, morbidity and mortality rates due to DHF. Data were analyzed using the Incidence Rate (IR) and Case Fatality Rate (CFR) formulas. Results: The number of dengue cases in East Java in 2015 to 2017 fluctuated. DHF morbidity rates have increased in 2016 while 2017 has decreased. The mortality rate in East Java in 2015-2017 has decreased. DHF events often occur in male sex. Conclusion: Dengue Hemorrhagic Fever is a vector-borne disease with rapid spread. The occurrence of dengue hemorrhagic fever every year there is an increase in cases and deaths of almost all regencies / cities in East Java.


2013 ◽  
Vol 3 (3) ◽  
Author(s):  
Janno B. B. Bernadus ◽  
Victor D. Pijoh ◽  
Venny Kareth

Abstract: Dengue Hemorrhagic Fever (DHF) has become a public health problem in Indonesia because of its high prevalence and ability to spread more widely. In North Sulawesi itself Case Fatality Rate of carrying dengue is increasing from year to year. The local village Malalayang has a high potential for spreading this disease. The result of an  entomology survey on adult mosquitos showed that Aedes sp was found in 40 houses of 80 house samples. From these 40 houses we got 71 mosquito samples. From these 71 samples tested and identified, we found three species: Aedes aegypti (30 samples, 42.25%), Aedes albopictus (22 samples, 30.99%), and Culex sp (19 samples, 26.76%). Mosquito density can be seen from the indices of the resting rates, which were 0.375 for Aedes aegypti, 0.275 for Aedes albopictus, and 0.65 for Aedes sp. Key words: density, adult mosquito, Aedes sp., resting rate.   Abstrak: Demam Berdarah Dengue (DBD) merupakan penyakit yang menjadi masalah kesehatan masyarakat di Indonesia karena prevalensinya yang tinggi dan penyebarannya semakin luas. Di Sulawesi Utara, Case Fatality Rate penyakit DBD tercatat terus meningkat dari tahun ke tahun. Kelurahan Malalayang I merupakan daerah yang potensial sebagai daerah penyebaran DBD. Survei entomologi terhadap nyamuk dewasa Aedes sp pada 80 rumah  memperlihatkan bahwa 40 diantaranya terdapat 71 sampel nyamuk. Setelah diperiksa dan diidentifikasi ternyata ditemukan tiga spesies yaitu Aedes aegypti 30 sampel (42,25%), Aedes albopictus 22 sampel (30,99%) dan Culex sp 19 (26,76%). Kepadatan nyamuk  dapat dilihat  dari angka indeks  pada resting rate yaitu Aedes aegypti = 0,375 , Aedes albopictus = 0,275 dan  Aedes sp.= 0,65. Kata kunci:  kepadatan, nyamuk dewasa, Aedes sp., resting rate.


2019 ◽  
Vol 6 (5) ◽  
pp. 2046
Author(s):  
Dharmendra Rawat ◽  
Kanwar Singh ◽  
Pukhraj Garg

Background: Dengue infection is a major challenge to public health, especially in South-East Asia. It present with a diverse clinical spectrum. Estimates suggest that annually over 50 million cases of dengue hemorrhagic fever (DHF) occur in Asian countries with a case fatality rate of less than 5%. Of those with DHF, at least 90% are children younger than 15 years old. In humans, dengue infection causes a spectrum of illness ranging from relatively mild, non-specific viral syndrome known as Dengue fever (DF) to severe hemorrhagic disease and death. Definitive early Dengue diagnosis requires laboratory tests and those suitable for use at this stage of illness are either costly, such as RT-PCR for Dengue; not sufficiently rapid, such as virus isolation. Currently test available are NS1 antigen detection and ELISA for dengue, IgM and IgG antibodies. Objective of this study is to study clinico-epidemiological and haematological features of Dengue infection.Methods: Prospective observational study involving initial 100 registered cases who were serologically confirmed dengue infection for a period of one year.Results: DF, DHF and DSS were found in 41%, 53% and 6% patients respectively. Most common presenting complaint and bleeding manifestation were fever and petechiae. Uncommonly altered sensorium and icterus were found in severe dengue infection. 6% patients had coagulopathy, 37 patients had hepatic involvement and 2 patients had deranged renal function who had DSS. Fever was present in (100%) cases of DF, DHF and DSS. 26% patients had their platelet count <50000/mm3.Conclusions: Dengue is a common disease in the India with wide spectrum of clinical presentations, affecting 5-15 years age group children commonly. It is one of the dreaded fevers but early diagnosis and management according to recent WHO guidelines can decrease case fatality rate significantly.


1999 ◽  
Vol 122 (1) ◽  
pp. 161-166 ◽  
Author(s):  
O. CHAREONSOOK ◽  
H. M. FOY ◽  
A. TEERARATKUL ◽  
N. SILARUG

Dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) are reportable diseases, the third most common causes for hospitalization of children in Thailand. Data collected from the Ministry of Public Health were analysed for trends. Rates of DHF increased in Thailand until 1987 when the largest epidemic ever, 325/100000 population, was recorded. Whereas the disease used to be confined to large cities, the rate is now higher in rural (102·2 per 100000) than urban areas (95·4 per 100000 in 1997). The age of highest incidence has increased, and the age group most severely affected is now those 5–9 years old (679/100000 in 1997). The case fatality rate has decreased with improved treatment and is now only 0·28%.


Author(s):  
Dong Miao ◽  
Ming-Jin Liu ◽  
Yi-Xing Wang ◽  
Xiang Ren ◽  
Qing-Bin Lu ◽  
...  

Abstract Background The growing epidemics of severe fever with thrombocytopenia syndrome (SFTS), an emerging tick-borne disease in East Asia, and its high case fatality rate have raised serious public health concerns. Methods Surveillance data on laboratory-confirmed SFTS cases in China were collected. The spatiotemporal dynamics and epidemiological features were explored. The socioeconomic and environmental drivers were identified for SFTS diffusion using survival analysis and for SFTS persistence using a two-stage generalized boosted regression tree model. Results During 2010‒2018, a total of 7721 laboratory-confirmed SFTS cases were reported in China, with an overall case fatality rate (CFR) of 10.5%. The average annual incidence increased &gt;20 times and endemic areas expanded from 27 to 1574 townships, whereas the CFR declined from 19% to 10% during this period. Four geographical clusters—the Changbai Mountain area, the Jiaodong Peninsula, the Taishan Mountain area, and the Huaiyangshan Mountain area—were identified. Diffusion and persistence of the disease were both driven by elevation, high coverages of woods, crops, and shrubs, and the vicinity of habitats of migratory birds but had different meteorological drivers. Residents ≥60 years old in rural areas with crop fields and tea farms were at increased risk to SFTS. Conclusions Surveillance of SFTS and intervention programs need to be targeted at areas ecologically suitability for vector ticks and in the vicinity of migratory birds to curb the growing epidemic.


1970 ◽  
Vol 37 (2) ◽  
pp. 66-70 ◽  
Author(s):  
A Pal ◽  
R Bhattacharyya ◽  
S Adhikari ◽  
A Roy ◽  
D Chakrabarty ◽  
...  

This cross sectional record based institutional study was conducted in the Department of Obstetrics & Gynaecology, Burdwan Medical College, Burdwan over ten years (1999-2008) aiming analysis of eclamptic mothers for evaluation of maternal and perinatal outcome with different anticonvulsant medications. Total 5991 pregnant mothers with eclampsia admitted in the inpatient department of the tertiary care teaching hospital were recruited for the study, irrespective of their previous antenatal check up history. Subjects with known seizure disorders were excluded from the study. The subjects were managed according to standard regimens (Menon, Ph-sodium, diazepam & magnesium sulphate) and results were documented in standardised format. Case fatality rate, mean induction delivery time & birth-weight, perinatal mortality rates were recorded. Study reveals that the incidence of eclampsia <20 years was 6.97% and majority (5.41%) came from rural areas. Eclampsia was noted primarily in primigravida (7.43%) and unbooked (6.41%) mothers. Ante partum eclampsia predominated (64%) and incidence of caesarean section was 22.25%.The overall case fatality rate was 6.05% and eclampsia contributed 27.85% of all maternal deaths during the last two years of the study period. The overall incidence of low birth weight baby was 26.96% and perinatal mortality was 30.33% (1411/4651).The incidence of perinatal mortality and low birth weight babies are lower in the last 4 years when compared to earlier studies. Proper socio-demographic assessment of pregnancy with eclampsia, planned delivery, shorter induction delivery interval, good control of convulsion by magnesium sulphate, intensive intranatal monitoring causes less maternal and perinatal morbidity and mortality. DOI: http://dx.doi.org/10.3329/bmrcb.v37i2.8437 BMRCB 2011; 37(2): 66-70


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