scholarly journals 34. Anatomical Pathology And Histopathological Changes Of Ascaridia Galli In Layer Chicken

2019 ◽  
Vol 13 (2) ◽  
Author(s):  
Muhammad Hambal ◽  
Rizki Efriyendi ◽  
Henni Vanda ◽  
Rusli Rusli

This study aimed to determine the anatomical pathology and histopathological, and their relationship of the ascaridiosis caused by Ascaridia galli worms infection that have been found in layer chickens after necropsy, thus facilitating the diagnosis, treatment, and prevention of ascaridiosis. This study used 1 dead chicken from the Lambaro traditional market, Ingin Jaya District, Aceh Besar Regency. The sample was taken to the Pathology Laboratory, Faculty of Veterinary Medicine, Syiah Kuala University for dissected and observed in anatomical pathology changes, then histopathological preparations were made to observe histopathological changes. Data were obtained then analyzed descriptively and presented in the form of images. The results of anatomical pathology examination in chickens infected with ascaridiosis were found the Ascaridia galli worms infestation in the intestinal lumen with moderate infestation rates and focal area of hemorrhage in the intestinal mucosa. Then, histopathological examination were found desquamation of villous epithelium, hemorrhage in the intestinal mucosa, inflammatory cell infiltration, and proliferation of cryptic cells caused by A. galli worms infection. Based on the results of the examination concluded that there is an association between anatomical and histopathological pathology findings, namely hemorrhage in the intestine.

e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Syendi Tanriono

Abstract: Cancer is a class of diseases characterized by uncontrolled cell division and the ability of these cells to invade other biological tissues, either by direct growth in adjacent tissue (invasion) or by migration of cells to distant sites (metastasis). There are several methods that can be used in diagnosis of cancer. But until now, the gold standard to diagnosis of cancer is histopathological examination. The examination can determine the type of both malignant and benign cancers. Currently, breast cancer is one of the most prevalent cancers in worldwide, and became the highest cause of death from the other cancers. That is why the research was conducted in order to find out an overview of breast cancer histopathology. This research is a descriptive retrospective survey method through data collection, analysis, and evaluation of the amount of histopathological examination of breast cancer patients in the Anatomical Pathology Laboratory Manado period January 2012- December 2012. Data collected through the analysis of 163 medical records description of breast cancer histopathological period of January 2012- December 2012 were selected from a total sampling methods. These results indicate that the description of breast cancer histopathology most commonly found in the Anatomical Pathology Laboratory Manado period January 2012- December 2012 were fibroadenomas were 62 cases ( 38.1 % ) and ductal invasive carcinoma followed by 49 cases ( 30.1 % ). Most women and the most common age group 40-49 years. Breast cancer histopathology most commonly found in the Anatomical Pathology Laboratory Manado period January 2012- December 2012 were fibroadenomas were 62 cases ( 38.1 % ) and ductal invasive carcinoma followed by 49 cases ( 30.1 % ).Key words: breast cancer, histopathology   Abstrak: Kanker merupakan segolongan penyakit yang ditandai dengan pembelahan sel yang tidak terkendali dan kemampuan sel-sel tersebut untuk menyerang jaringan biologis lainya , baik dengan pertumbuhan langsung di jaringan yang bersebelahan (Invasi) atau dengan migrasi sel ke tempat yang jauh (metastasis). Ada beberapa metode yang dapat digunakan dalam mendiagnosis kanker. Tetapi sampai sekarang yang menjadi gold standard dalam mendiagnosis kanker adalah pemeriksaan histopatologi. Dimana dalam pemeriksaan ini dapat menentukan jenis kanker baik ganas maupun jinak. Saat ini kanker payudara merupakan salah satu kanker yang paling banyak dijumpai diseluruh dunia, dan menjadi penyebab kematian tertinggi akibat kanker. Maka dari itulah penelitian ini dilakukan guna untuk mencari tahu gambaran histopatologi kanker payudara. Penelitian ini merupakan penelitian bersifat deskriptif dengan metode survey retrospektif melalui pengumpulan data, analisis, dan evaluasi jumlah hasil pemeriksaan histopatologi penderita kanker payudara di Laboratorium Patologi Anatomi Manado periode januari 2012-desember 2012. Pengumpulan data dilakukan melalui analisis pada 163 data rekam medis dari gambaran histopatologi kanker payudara periode januari 2012-desember 2012 yang dipilih dari metode total sampling. Hasil penelitian ini menunjukan bahwa gambaran histopatologi kanker payudara yang paling banyak ditemukan di Laboratorium Patologi Anatomi Manado periode januari 2012-desember 2012 adalah fibroadenoma sebanyak 62 kasus (38.1%) dan diikuti duktal karsinoma invasif sebanyak 49 kasus (30.1%). Terbanyak pada perempuan dan umur tersering golongan 40-49 tahun. Gambaran histopatologi kanker payudara terbanyak di Laboratorium Patologi Anatomi Manado periode januari 2012-desember 2012 adalah fibroadenoma sebanyak 62 kasus (38.1%) dan diikuti duktal karsinoma invasif sebanyak 49 kasus (30.1%). Kata kunci: kanker payudara, histopatologi


2020 ◽  
Vol 150 ◽  
Author(s):  
M. Michalczyk ◽  
R. Sokół ◽  
M. Gesek ◽  
M. Mączyński ◽  
D. Będzłowicz

The aim of this study was to analyze the parasitic fauna of dead white storks in nesting sites in different parts of Poland and the associated histopathological changes. Samples from thirty-eight white storks aged 3 weeks to 5 years were examined after their arrival at a stork sanctuary. The presence of Cathaemasia hians, Chaunocephalus ferox, Choanotaenia infundibulum, Railletina tetragona and Syngamus trachea was confirmed in 17 out of 38 (47.73 %) individuals. Cathaemasia hians and Chaunocephalus ferox flukes are not endemic to the studied area. The frequency of C. ferox was significantly higher in the youngest storks from group I (3–4 weeks old) compared to groups II (11–15 weeks old) and III (older than 2 years). Fluke eggs were only detected with sedimentation method in three samples (group III), while no adult flukes at all were found in the intestines. Chaunocephalus ferox was shown to be the most common pathogen in all storks studied when compared to other parasites. A histopathological examination of the jejunum and ileum revealed atherosclerotic changes in the muscular layer, lymphoid infiltration in the mucosa, the presence of adult flukes of C. hians and C. ferox in the intestinal lumen, and lymphoid infiltration in the muscular layer. Intense lymphoid infiltration in the mucosa was also observed in storks whose intestines were heavily infested with R. tetragona and C. infundibulum. Parasitic infections compromise the birds’ health status and affect the duration of flights, and they can increase the risk of other diseases.


Author(s):  
Hemant Nargawe ◽  
Sumeet Sisodiya

Background & Method: The study was conducted in the Department of Medicine Shyam Shah Medical College and Associated Sanjay Gandhi Memorial Hospital, Rewa (M.P). History was followed by a careful clinical examination i.e. cardiovascular, respiratory and gastrointestinal and nervous system. Investigations had done included routine haematological examination, Biochemical analysis, urine examination, ECG, 2 D. Echo & Histopathological examination was done. Result: ST-T changes were most common finding in Aluminium phosphide poisoning in relation to mortality. However hyperkalemia was the most ominous finding associated with 100% mortality, ECG finding in EDB was normal ECG. The most ominous finding was arrhythmia which was associated with 100% mortality. Survivors of ethylene dibromide poisoning echocardiography was normal in 11 (84.61%) followed by pericardial effusion in 2 (15.38%) patients. Conclusion: Noteworthy finding was absence of correlation between cardiovascular involvement, histopathological changes and ECG findings. It was seen that even if ECG showed normal pattern there were significant histopathological changes in heart. Keywords: electro-cardiographic, Aluminium phosphide, ethylene dibromide & poisoning.


2017 ◽  
Vol 23 (2) ◽  
Author(s):  
SHASHI KIRAN

The objective of this study was to determine the relationship of C. fasciolaris with common rats. Cysticercus fasciolaris is the larval stage of Taenia taeniaeformis . Development of metacestodes ( Cysticercus fasciolaris) occur in the liver of rodents. An urban and a sylvatic cycle occurs. A total of 40 liver specimens of rats were examined. Histopathological examination revealed the presence of multiple hepatic cysts, and the C. fasciolaris larva was surrounded by granulation tissue. Large and separated ûbroblasts in different orientations with some neoplastic changes were seen in advanced hepatic cysticercosis. The bladder involved the larva and large chamber containing the small chamber and opalescent fluid. The scolex of the mature larva is distinctly large, bearing four lateral distinct suckers, a rostellum armed with double, and alternating rows of hooks.


2011 ◽  
Vol 300 (1) ◽  
pp. G164-G169 ◽  
Author(s):  
Michelle R. Adams ◽  
Eddy Konaniah ◽  
James G. Cash ◽  
David Y. Hui

The importance of Niemann-Pick C1 Like-1 (NPC1L1) protein in intestinal absorption of dietary sterols, including both cholesterol and phytosterols, is well documented. However, the exact mechanism by which NPC1L1 facilitates cholesterol transport remains controversial. This study administered 22-( N(-7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-23,24-bisnor-5-cholen-3β-ol (NBD-cholesterol) and [3H]cholesterol to Npc1l1+/+ and Npc1l1−/− mice to determine whether NPC1L1 facilitates dietary sterol uptake by enterocytes and/or participates in intracellular sterol delivery to the endoplasmic reticulum (ER) for lipoprotein assembly before secretion into plasma circulation. Results showed that [3H]cholesterol absorption was reduced but not abolished in Npc1l1−/− mice compared with Npc1l1+/+ mice. In the presence of Pluronic L-81 to block pre-chylomicron exit from the ER, significant amounts of [3H]cholesterol were found to be associated with lipid droplets in the intestinal mucosa of both Npc1l1+/+ and Npc1l1−/− mice, and the intracellular [3H]cholesterol can be esterified to cholesteryl esters. These results provided evidence indicating that the main function of NPC1L1 is to promote cholesterol uptake from the intestinal lumen but that it is not necessary for intracellular cholesterol transport to the ER. Surprisingly, NBD-cholesterol was taken up by intestinal mucosa, esterified to NBD-cholesteryl esters, and transported to plasma circulation to similar extent between Npc1l1+/+ and Npc1l1−/− mice. Ezetimibe treatment also had no impact on NBD-cholesterol absorption by Npc1l1+/+ mice. Thus, NBD-cholesterol absorption proceeds through an NPC1L1-independent and ezetimibe-insensitive sterol absorption mechanism. Taken together, these results indicate that NBD-cholesterol can be used to trace the alternative cholesterol absorption pathway but is not suitable for tracking NPC1L1-mediated cholesterol absorption.


2018 ◽  
Vol 41 (2) ◽  
pp. 203-207
Author(s):  
Ivica Gjurovski ◽  
Monika Dovenska ◽  
Aleksandar Janevski ◽  
Trpe Ristoski

Abstract The illegal poisoning of dogs and other domestic and wild animals presents a worldwide problem causing animal suffering and R. Macedonia is not an exeption. The goal of this study is to make a comparison of the results from the histopathological examination conducted among poisoned dogs in the Republic of Macedonia. Morphological and histopathological changes in poisoned dogs were investigated for a period of 10 years. The examination was performed on 31 dogs, 13 of which were home kept, 7 were street dogs and 11 of unknown origin. The most significant necropsy findings concerned the inflammatory and necrotic processes of the gastrointestinal tract. The histopathological changes were mainly located in the kidneys, stomach, intestines and the lungs.


2021 ◽  
Vol 3 (1) ◽  
pp. 38-43
Author(s):  
Arin Dwi Afrida ◽  
Djoko Priyatno

Histopathological examination is a routine examination process for each tissue in the anatomic pathology laboratory. The stages in making histology preparations are fixation stages. The type of solution that can be used as a fixative solution other than 10% NBF is Carnoy's solution. Carnoy's solution is a fixative solution with a relatively fast fixation process of about 1-4 hours. The advantages of Carnoy's solution can lyse erythrocytes and dissolve lipids, have the ability to maintain cell nuclei, and retain glycogen. The purpose of this study was to determine the histology of the liver tissue preparations of mice (Mus Musculus) which were fixed using Carnoy's solution with time variations of 4 hours, 8 hours, and 12 hours. This is an observational research with descriptive research design criteria. The results of the histology of the liver tissue preparations of mice (Mus Musculus) which were fixed using the 10% NBF solution group obtained 100% good preparations. In the Carnoy solution group with a time of 4 hours, it gave 2.2% results of poor preparations and 97.78% of good preparations. While the treatment group with Carnoy's solution with a time of 8 hours obtained as many as 11.11% of preparations that were not good and 88.89% of good preparations. and in the Carnoy solution group with a time of 12 hours, there were 44.44% of the poor preparations and 55.56% of the good preparations.


1983 ◽  
Vol 61 (4) ◽  
pp. 349-355 ◽  
Author(s):  
Armin Wollin ◽  
Henri Navert

Diamine oxidase activity was measured in the intestinal mucosa, lymph, and in the serum of rats, to determine whether histamine, a substrate of diamine oxidase, liberates this enzyme from its mucosal storage site(s). Histamine induced a sharp rise in intestinal lymph flow, lymph protein, and lymph diamine oxidase, lasting less than 1 h after the histamine injection. The rise in lymph diamine oxidase activity was dose dependent over a narrow concentration range (0.05–0.2 mmol/kg, i.v. and 0.15–0.6 mmol/kg i.d.). It did not correlate with the dose dependent increase in lymph flow or lymph protein. A single maximal intraduodenal dose of histamine caused a 41.6-fold increase in the lymph diamine oxidase activity and a 2.4-fold increase in the serum enzyme level temporarily. A second injection of histamine, 2 h after the first, resulted in a comparatively smaller increase in the lymph enzyme. The extent of the reduction was dependent on the magnitude of the first injection. The results suggest that histamine causes a limited liberation of diamine oxidase from the intestinal mucosa. The function of this enzyme release may be a protective response by the mucosa to reduce toxic levels of free histamine, either liberated by the mucosal tissue or absorbed from the intestinal lumen.


2013 ◽  
Vol 3 (5) ◽  
pp. 356-360 ◽  
Author(s):  
S Gon ◽  
A Basu ◽  
B Majumdar ◽  
TK Das ◽  
M Sengupta ◽  
...  

Background: Fallopian tubes are common surgical specimen in the pathology laboratory; still there is a lack of data to describe the frequency of various histological fi ndings. The aim and objectives of this study was to describe the various histopathological fi ndings of fallopian tubes. Materials and Methods: Two thousand fi ve hundred and seventy fi ve cases where fallopian tubes were removed either separately or along with other female genital tract organs were studied retrospectively and their histopathological fi ndings documented. Results: Ectopic pregnancy comprised maximum number of cases closely followed by salpingitis. Primary neoplastic lesions were rare as compared to secondary malignancies. Serial sections of fallopian tube and sections from representative areas are essential for a pathologist so that the diagnosis of these pathological entities is not missed. Conclusion: Though the fallopian tubes remain unremarkable in majority of the surgical pathological specimens, it must be subjected for histopathological examination to demonstrate the pathological lesions. Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 356-360 DOI: http://dx.doi.org/10.3126/jpn.v3i5.7858


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