scholarly journals Prevalence of Generalized Joint Hypermobility in Children with Anxiety Disorders

2020 ◽  
Author(s):  
vadood javadi ◽  
Shadi alsadat Modarres ◽  
Ghazal Zahed ◽  
Reza Shiari ◽  
Khosro Rahmani
Keyword(s):  
Anxiety Disorders ◽  
Joint Hypermobility ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Hypermobility Syndrome ◽  
Generalized Joint Hypermobility ◽  
High Prevalence ◽  
And Control ◽  
Control Study

Abstract Background: Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the association of hypermobility with anxiety disorders in children. Methods: In this case-control study, 93 children ages 8-15 years with anxiety disorders referring to the Child and Adolescent Psychiatry Clinic of Mofid Children’s Hospital, Tehran, Iran, during 2018, were enrolled. The control group consisted of 100 age and sex-matched children without anxiety disorders. Anxiety was evaluated using the Spence Children Anxiety Scale (SCAS). The diagnosis of generalized joint hypermobility was done based on Beighton and Shiari-Javadi criteria. Results: Based on Beighton’s diagnostic criteria 52.7% of the children in the case group and 16% of the children in the control group had generalized joint hypermobility. Moreover, based on Shiari-Javadi criteria, 49.5% and 13% of the children in the case and control groups had generalized joint hypermobility, respectively. Moreover, the internal correlation between the two criteria was 0.91 showing almost complete compatibility between the two (P<0.001). Age was a risk factor that could predict hypermobility in these children. Other variables such as sex, severity, and type of anxiety disorders, and ADHD, were not predictors of hypermobility syndrome. Conclusion: The prevalence of hypermobility was three times higher in children with anxiety disorders and only age was a predictor for the possibility to suffer from generalized joint hypermobility in these children.

Prevalence of Generalized Joint Hypermobility in Children with Anxiety Disorders

2020 ◽  
Author(s):  
vadood javadi ◽  
Shadi Sadat Modarres ◽  
Ghazal Zahed ◽  
Reza Shiari ◽  
Khosro Rahmani
Keyword(s):  
Anxiety Disorders ◽  
Joint Hypermobility ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Generalized Joint Hypermobility ◽  
High Prevalence ◽  
And Control ◽  
The Relationship ◽  
Control Study

Abstract Background Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the relationship between the prevalence of hypermobility and anxiety disorders in children. MethodsIn this case-control study, 93 children ages 8-15 years with anxiety disorders referring to the Child and Adolescent Psychiatry Clinic of Mofid Children’s Hospital, Tehran, Iran, during 2018, were enrolled. The control group consisted of 100 age and sex-matched children without anxiety disorders. Anxiety was evaluated using the Spence Children Anxiety Scale (SCAS). The diagnosis of generalized joint hypermobility was done based on Beighton and Shiari-Javadi criteria. Results Based on Beighton’s diagnostic criteria 52.7% of the children in the case group and 16% of the children in the control group had generalized joint hypermobility. Moreover, based on Shiari-Javadi criteria, 49.5% and 13% of the children in the case and control groups had generalized joint hypermobility, respectively. Moreover, the internal correlation between the two criteria was 0.91 showing almost complete compatibility between the two (P<0.001). Age was a risk factor that could predict hypermobility in these children. Other variables such as sex, severity, and type of anxiety disorders, and ADHD, were not predictors of hypermobility syndrome. Conclusion The prevalence of hypermobility was three times higher in children with anxiety disorders and only age was a predictor for the possibility to suffer from generalized joint hypermobility in these children.

Prolonged rooming-in in infancy is associated with generalized anxiety disorder in the adolescent period

2015 ◽  
Vol 27 (4) ◽  
pp. 383-389 ◽  
Author(s):  
Nazan Kaymaz ◽  
Emel Sarı Gökten ◽  
Mehmet Erdem Uzun ◽  
Şule Yıldırım ◽  
Mustafa Tekin ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Generalized Anxiety Disorder ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Generalized Anxiety ◽  
Bed Sharing ◽  
Self Confidence ◽  
Long Time

Abstract Objective: This study aims to investigate whether anxiety disorders in adolescents have a link with the separation time of bed/bedroom sharing with parents. It also aims to raise awareness in society about the issue of minimizing anxiety disorders in childhood. Methods: A case-control study was conducted in Şevket Yılmaz Training and Research Hospital between June 2013 and May 2014. The participants included 51 adolescents who were diagnosed as generalized anxiety disorder (GAD) with no-comorbidity and 71 healthy adolescents as the control group, who were chosen randomly. Diagnosis of GAD was based on the criteria from the Diagnostic and Statistical Manual of Mental Disorders (4th ed) by child and adolescent psychiatry doctors. The Turkish version of the State-Trait Anxiety Inventory (STAI) was used for the control group. A special survey about demographics and bed-sharing statements was constructed for the purpose of the study. The groups were analyzed in terms of duration of co-sleeping (bed-sharing) and rooming-in (keeping the mother and the baby in same room) with parents during infancy and the development of anxiety disorders in later period. Results: Mean duration of rooming-in was significantly longer in the case group than in the control group (p=0.009). Similarly, mean duration of co-sleeping in the case group was longer than that of the control group. However, this difference was not statistically significant (p=0.529). Conclusion: Sleeping in the same room with children for a long time may result in anxiety disorders in later period due to possible difficulties in bonding and/or less self-confidence.

A Case-Control Study on the p73 G4A Gene Polymorphism and Susceptibility to Breast Cancer in an Iranian Population

2020 ◽  
Author(s):  
Zeinab TAVAKKOL AFSHARI ◽  
Zahra GHOLIZADEH ◽  
Amin Reza NIKPOOR ◽  
Jalil TAVAKKOL AFSHARI ◽  
Rashin GANJALI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Iranian Population ◽  
Control Group ◽  
Case Group ◽  
Medical Sciences ◽  
Control Groups ◽  
And Control ◽  
Control Study

Background: The tumor protein p73 (TP73) is a homolog of TP53 family. Ectopic p73 overexpression largely mimics p53 activities as a tumor suppressor and activates the transcription of p53-responsive genes and as a result induce apoptosis. This study aimed to investigate the association between p73 G4A polymorphism and the risk of breast cancer in a northeastern Iranian population. Methods: This case-control study was performed on 105 patients who admitted in educational hospitals of Mashhad University of Medical Sciences, Iran during 2013-2015, with breast cancer as case group and 120 healthy women as the control group. PCR-CTPP method was used to investigate the relationship between the p73 G4A polymorphism and the risk of breast cancer. Results: There was no significant association between the AA genotype of the p73 G4A polymorphism and breast cancer in case and control groups. Although G allele frequency was higher in the case group, the abundance of this allele between case and control groups was not statistically meaningful and, as a result, not associated with the risk of breast cancer in this study group. Conclusion: There was no association between G4A p73 polymorphism and the risk of breast cancer in a northeastern Iranian population.  

scholarly journals Relationship between small for gestational age and aortic intima-media thickness in newborns

2014 ◽  
Vol 54 (1) ◽  
pp. 57 ◽  
Author(s):  
Ahmad Bayu Alfarizi ◽  
Ria Nova ◽  
Julniar Mawardi Tasli ◽  
Theodorus Theodorus
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Intima Media Thickness ◽  
Control Group ◽  
Case Group ◽  
Media Thickness ◽  
And Control ◽  
Aortic Intima ◽  
The Relationship ◽  
Control Study

Background Small for gestational age (SGA) has been associatedwith adult cardiovascular disease. Small for gestational agenewborns may undergo early aortic wall intima-media thickening(aIMT) in utero.Objective To determine the relationship between SGA as a riskfactor for increased aIMT, as a sign of atherosclerosis onset.Methods We conducted a case-control study in the Neonatal Wardand Rooming-in Nursery at Dr. Mohammad Hoesin Hospital,Palembang, between April to June 2012. Subjects were allocatedto either the case group (aIMT 2: 0.9 mm) or to the controlgroup (aIMT <0.9 mm). Newborns were classified as SGA iftheir birthweight (BW) was < l O'h percentile, and appropriatefor gestational age (AGA) if their BW was between lQth - 90'hpercentile, according to the Lubchenco curve. Abdominal aorticintima-media thickness was measured by echocardiographyexamination.Results The case and control groups consisted of 30 n ewbornseach. The proportion of SGA newborns was higher in the casegroup than the control group. The likelihood of infants in the casegroup being SGA was significantly higher compared to the controlgroup, with odds ratio of 10.8 (95%CI 3,26 to 35, 72) . The meanaIMT was significantly higher in SGA than in AGA infants, 0.9(SD 0.16) mm vs. 0.8 (SD 0.13) mm, respectively, with a meandifference of 0, 13 (9 5% CI 0, 050 to 0,209 mm; P"" 0,02).Conclusion Increased aIMT is more likely found in SGA newborns.

scholarly journals The study of Effective Factors on Breast Cancer in Ardabil

2021 ◽  
Vol 15 (7) ◽  
pp. 1991-1993
Author(s):  
Davoud Adham ◽  
Eslam Moradi-Asl, Malek Abazari
Keyword(s):  
Breast Cancer ◽  
Classification Tree ◽  
Control Group ◽  
Case Group ◽  
Effective Factors ◽  
Cancer Breast ◽  
High Prevalence ◽  
Tree Models ◽  
Keywords Cancer ◽  
And Control

Background: The prevalence of breast cancer is about one third of all cancers in women constitute the second most common cancer after lung cancer and the most common cause of cancer death among women. Because of high prevalence, study of effective factors on breast cancer in Ardabil area is a very important. Method: In this case-control study, 100 women were selected from the breast cancer clinic that referred to hospitals in the Ardabil city in 2014 year. In addition, 100 healthy women were that referred to health centers in Ardabil city, selected for cluster and were considered as the control group. For statistical analysis and investigation of the influencing factors on breast cancer used to classification tree models. Results: The analyses indicated that, 83 women from case group and 80 women from control group were married. The most common age for patients whit breast cancer was 15-49 years old with average 32/8 year and (SD= 8.3).40% of women whit breast cancer were less than 30 years. None of the women did not have breast secretions in the control groups but 43 women in case groups have breast secretions. Conclusion: The identification of risk factors in this study can be programmed to prevent and control breast cancer. Keywords: Cancer, Breast, Ardabil

scholarly journals Comparison of Maternal Functioning between Iranian Mothers with and without Depressive Symptoms: A Case-Control Study

2020 ◽  
Vol 17 (10) ◽  
pp. 3350
Author(s):  
Fatemeh Karami Chamgurdani ◽  
Jennifer L. Barkin ◽  
Carolann L. Curry ◽  
Mojgan Mirghafourvand
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Case Control Study ◽  
Pearson Correlation ◽  
Control Group ◽  
Case Group ◽  
Maternal Functioning ◽  
The Mean ◽  
And Control ◽  
Control Study

Postpartum depression (PPD) has adverse effects on the mother’s ability to work, her relationships, performance in other roles, and caregiving ability. The aim of this study was to compare levels of maternal functioning between mothers with depression symptoms and those without. The participants of this case-control study included 80 postpartum women (n = 40 with depressive symptoms and n = 40 with no depressive symptoms) referred to health centers in Tabriz, Iran, in 2018–2019. The case and control groups were matched for the number of deliveries (first or second deliveries) and the type of delivery (vaginal or cesarean section). A sociodemographic questionnaire, Edinburgh Postpartum Depression Scale (EPDS), and Barkin Index of Maternal Functioning (BIMF) were used for data collection. The relationship between maternal functioning and depression was assessed by conducting independent t-tests and Pearson correlation tests in bivariate analysis and applying the general linear model (GLM) in a multivariate analysis. There was no statistically significant difference between the two groups in terms of sociodemographic information. The mean (SD) total scores of maternal functioning in the case (depressed) and control (non-depressed) groups were 63.4 (12.2) and 93.3 (13.0), respectively. According to the independent t-test, this value in the control group was significantly higher than that of the case group (mean difference: −30.0; 95% confidence interval: −35.6 to −24.3; p < 0.001). In terms of the domains of the BIMF, based on the independent t-test, the mean score of all domains in the control group was significantly higher than that of the case group, except for the mother-child interaction dimension (p = 0.219). Based on the Pearson correlation test, there was significant negative correlation between the PPD score and total score of BIMF (r = −0.79, p < 0.001) and its domains (r = −0.81 to −0.54, p < 0.001). In addition, based on the GLM with adjusting the sociodemographic and obstetrics characteristics, the score of maternal functioning was significantly lower in the case group compared to the control group [β = −30.1; 95% CI: −36.8 to −23.4; p = 0.001]. The results of this study indicate that women with depressive symptoms have lower maternal functioning. Depressed women may find it difficult to perform their maternal duties and take care of themselves and other family members due to the burden of the depressive symptoms. Therefore, early diagnosis and treatment of postpartum depression can play an important role in improving daily maternal functioning.

Zinc deficiency is an independent risk factor for prehypertension in healthy subjects

2019 ◽  
pp. 1-6 ◽  
Author(s):  
Sara C. Nevárez-López ◽  
Luis E. Simental-Mendía ◽  
Fernando Guerrero-Romero ◽  
Jorge A. Burciaga-Nava
Keyword(s):  
Blood Pressure ◽  
Zinc Deficiency ◽  
Healthy Subjects ◽  
Serum Zinc ◽  
Control Group ◽  
Case Group ◽  
Zinc Levels ◽  
And Control ◽  
Control Study ◽  
Apparently Healthy

Abstract. Objective: To assess whether zinc deficiency is associated with prehypertension (preHTN) in apparently healthy subjects. Design: Apparently healthy women and men, aged 20 to 60 years were enrolled into a case-control study. Individuals with and without preHTN were allocated into the case and control groups, respectively. Hypertension, liver disease, renal disease, smoking, pregnancy, diabetes, malignancy, hypernatremia, hypomagnesemia, medical treatment, and use of supplements containing zinc were exclusion criteria. PreHTN was defined by systolic blood pressure (SBP) and/or diastolic blood pressure (DBP) of 120–139 mmHg and/or of 80–89 mmHg, respectively, and the zinc deficiency by serum zinc levels < 74 μg/dL in men and < 70 μg/dL in women. Results: In total, 142 subjects (90 women and 52 men) were enrolled and allocated in the case (n = 71) and control (n = 71) groups. In the overall population, the frequency of zinc deficiency was 11.1%; individuals in the case group showed significant higher frequency of zinc deficiency as compared with the control group (16.9% vs 5.5%, p = 0.04). The logistic regression analysis showed a significant association between zinc deficiency and preHTN (OR = 4.61; 95% CI: 1.24–17.12, p = 0.02). Conclusion: Our results suggest that zinc deficiency is associated with the presence of preHTN in apparently healthy subjects.

scholarly journals Efficacy of Operculectomy in the Treatment of 145 Cases with Unerupted Second Molars: A Retrospective Case–Control Study

2020 ◽  
Vol 8 (3) ◽  
pp. 65 ◽  
Author(s):  
Andrea Abate ◽  
Davide Cavagnetto ◽  
Andrea Fama ◽  
Marco Matarese ◽  
Francesca Bellincioni ◽  
...  
Keyword(s):  
Control Group ◽  
Case Group ◽  
Inclusion Criteria ◽  
Control Groups ◽  
Retrospective Case ◽  
Second Molar ◽  
One Year ◽  
And Control ◽  
Lower Arch ◽  
Control Study

The aim of this study is to assess whether operculectomy in patients with retained second molars eases spontaneous tooth eruption in respect to untreated controls. Two hundred and twenty-two patients with delayed eruption of at least one second molar were selected from the archives of the Department of Orthodontics, Milan, Italy. Eighty-eight patients, 40 males and 48 females (mean age 14.8 ± 1.3 years), met the inclusion criteria. Records were then divided into case and control groups. The case group consisted of patients that underwent removal of the overlaying mucosa over second molars (i.e., operculectomy) and the control group consisted of subjects who retained their operculum over an unerupted second molar and were followed for one year without performing any treatment. A total of 145 impacted second molars were considered (75 cases, 70 controls). A risk ratio with 95% confidence interval was used to compare the prevalence of eruption in the two groups. Spontaneous eruption occurred in 93.3% of cases in the operculectomy group (70/75), while in the control group, 10% teeth erupted spontaneously (7/70). Spontaneous eruption in the upper arch occurred in 95.2% of cases among treated patients (40 out of 42), while in the lower arch, spontaneous eruption occurred in 90.9% of cases (30 out of 33). Spontaneous eruption of the upper second molars in the control group occurred in 8.5% of cases (3 out of 35), while in the lower arch, it occurred in 8.5% (3 out of 35). Operculectomy can ease the spontaneous eruption of retained second molars and reduce the chances of inclusion.

scholarly journals Depression and Anxiety Disorders among Patients with Psoriasis: A Hospital-Based Case-Control Study

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Masoud Golpour ◽  
Seyed Hamzeh Hosseini ◽  
Mohammad Khademloo ◽  
Maryam Ghasemi ◽  
Aghdas Ebadi ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Trait Anxiety ◽  
Case Control Study ◽  
Case Control ◽  
Anxiety Scale ◽  
Control Group ◽  
Depression And Anxiety ◽  
Dermatology Department ◽  
And Control ◽  
Control Study

Background. Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. Psychological stress can exacerbate the disease. This study sought to investigate the depression and anxiety disorders among patients with psoriasis and control group.Method. In this hospital-based case-control study, One hundred patients with psoriasis (case) referred to the dermatology department and 100 patients with otolaryngology problems and dermatological healthy volunteers (control) who referred to the Otolaryngology Department of Bouali Sina Hospital in Sari, Iran, in 2007 were studied. Demographic characteristics were recorded. Beck Depression Inventory and Spielberger State-Trait Anxiety Scale I-II were administered to the patients in both groups. Data were analyzed using SPSS statistical software and descriptive statistical tests.Results. From One-hundred patients in each group, 44 (45%) were men. Depression score was 67% and 12% in psoriatic patients and control, respectively. The Beck depression scores of patients with psoriasis were significantly higher than scores of the control group (P<0.05). Based on Spielberger State-Trait Anxiety Scale, anxiety was found in 45% of patients in case group and 18% of controls.Conclusion. The results revealed that psoriatic patients reported significantly higher degrees of depression and anxiety than controls. In addition, psoriatic women were more depressed than psoriatic men.

scholarly journals Bio-physicochemical markers of the Aedes aegypti breeding water in endemic and non-endemic area

2019 ◽  
Vol 8 (2) ◽  
pp. 151
Author(s):  
Nurul Hidayah ◽  
Dwi Rahmawati
Keyword(s):  
Aedes Aegypti ◽  
Endemic Area ◽  
Sampling Technique ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
Breeding Sites ◽  
Endemic Areas ◽  
And Control ◽  
Control Study

The survival of <em>Aedes aegypti</em> larvae is inseparable from the adequacy of food, including organic substances available in the breeding water. It is very dependent on the level of water markers such as temperature, salinity, Dissolved Oxygen, and pH. The study used quantitative observational analytic with a case-control study design. Case group has consisted of breeding water in endemic area and control group was in non-endemic area. The sample size was 43 samples for each group, collected by purposive sampling technique. Data were analyzed by Chi-square and Mann-Whitney test. Larvae mostly presence in endemic area (68.3%) and mostly absent in non-endemic area (85.4%) (<em>p</em>-value = 0.002). Temperature in endemic area mostly in 27-30<sup>o</sup>C (86%) and non-endemic area mostly in &lt;27<sup>o</sup>C or &gt;30<sup>o</sup>C (72.1%) (<em>p</em>-value = 0.000). Salinity in endemic and non-endemic areas has no difference (<em>p</em>-value = 0.266). DO in endemic areas were mostly in 5.02-7.82 mg/l (76.7%). While DO in non-endemic area was mostly in &lt;5.02 mg/l or &gt;7.82 mg/l (95.3%) (<em>p</em>-value = 0.001). The pH &lt;6 or &gt;7.8 is mostly in non-endemic areas (87.8%) and pH 6-7.8 is mostly in endemic areas (63.4%) (<em>p</em>-value = 0.000). Bio-physicochemical markers of breeding sites water have differences between endemic and non-endemic area except salinity. The temperature, salinity, DO, and pH affected the presence of larvae and the most affected is DO marker. While the marker that affected the presence of larvae in the non-endemic area is pH.

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