scholarly journals Ambient sulfur dioxide could have an impact on testicular volume from an observational study on a population of infertile male

2020 ◽  
Author(s):  
Yuan Chen ◽  
Yi-Kai Chang ◽  
Yann-Rong Su ◽  
Hong Chiang Chang
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Testicular Volume ◽  
University Hospital ◽  
Semen Parameters ◽  
Sperm Cells ◽  
Infertile Male ◽  
Negatively Associated ◽  
The Impact

Abstract Background The present retrospective study investigates the effect of environmental pollutants on male reproductive health. Methods Male patients with primary infertility (n = 282) from a single center (National Taiwan University Hospital, Taipei, Taiwan), between January 2016 and December 2017, were identified. Patients were physically examined for the presence of varicocele, and the volume of both testicles. Semen quality was measured in terms of total sperm count (millions), sperm concentration (millions/ml), and the percentage of motile sperm cells and the sperm cells with normal morphology. Data on the concentration of SO 2 (ppb), O3 (ppb), NO and NO 2 (ppb), and PM2.5 concentrations (μg/m3), measured on daily and hourly basis, were acquired from the Environmental Protection Administration Executive Yuan, Taiwan. Individual exposure to pollutants was estimated based on the reported residential address of patients. Statistical analysis indicated the impact of each pollutant on the testicular volume and semen parameters. Results Mean ± SD of age was 36.7 ± 7.3 years. The average sperm count and concentration was 41.9 million/ml and 34.1 million/ml, respectively. Except for PM2.5, the mean concentration of all the particulate matters were within the reference value. NO2 and SO2 exposure were negatively associated with the sperm concentration and motility, and testicular volume, respectively. Conclusions NO2 and SO 2 exposure were negatively associated with the sperm concentration and motility, and testicular volume, respectively, in a population of infertile male. Nevertheless, studies are needed to ascertain the impact of different exposure levels of pollutants on the semen parameters.

scholarly journals Ambient sulfur dioxide could have an impact on testicular volume from a observational study on a population of infertile male

BMC Urology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yu-An Chen ◽  
Yi-Kai Chang ◽  
Yann-Rong Su ◽  
Hong-Chiang Chang
Keyword(s):  
Sulfur Dioxide ◽  
Semen Quality ◽  
Sperm Count ◽  
Environmental Pollutants ◽  
Sperm Concentration ◽  
Serum Testosterone ◽  
Testicular Volume ◽  
Semen Parameters ◽  
Negatively Associated ◽  
The Mean

Abstract Background The effect of ambient pollutants on the male reproductive system is controversial. This retrospective study investigated the effect of environmental pollutants on male reproductive health. Methods Male patients with primary infertility (n = 282) were identified from a single center between January 2016 and December 2017. Patients were physically examined for the presence of varicocele and for the volume of both testicles. Semen quality was measured in terms of the total sperm count, sperm concentration, and the percentage of sperm cells with motility and normal morphology. Data were acquired on the concentration of ambient pollutants, namely particulate matters of diameter < 2.5 μm, sulfur dioxide (SO2), nitrogen oxides (NOx), and ozone (O3), measured on daily and hourly basis, from the Environmental Protection Administration Executive Yuan, Taiwan. Individual exposure to pollutants was estimated based on the reported residential address of each participant. Statistical analysis indicated the effect of each pollutant on the testicular volume, sex hormone profile, and semen parameters. Results The mean ± standard deviation of age was 36.7 ± 7.3 years. The average sperm count and concentration were 41.9 million/mL and 34.1 million/mL, respectively. The mean levels of serum testosterone, follicle-stimulating hormone, and luteinizing hormone were 3.57 ± 1.68 ng/mL, 7.59 ± 6.3 IU/L, and 4.68 ± 3.49 IU/L, respectively. According to the multivariate linear regression model, NOx exposure was a risk factor for decreased sperm concentration and motility (p = 0.043 and 0.032). Furthermore, SO2 exposure was negatively associated and testicular volume (p < 0.01). Conclusions NO2 and SO2 exposure were negatively associated with the seminal parameter and decreased testicular volume, respectively, in a population of men with infertility. However, additional prospective studies are needed to ascertain the cause–effect relation of current results.

scholarly journals What Is the Impact of Excessive Iodine and Semen Quality in Fertile Men of China: An Association Study 

2021 ◽  
Author(s):  
Ning Wang ◽  
Fang Lv ◽  
Ge Yu ◽  
Cuige Shi ◽  
Shangming Wang ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Male Reproduction ◽  
Semen Parameters ◽  
Human Thyroid ◽  
Urinary Iodine Concentration ◽  
The Impact

Abstract Background: Iodine is an essential element for hormones synthesized by the human thyroid gland. Thyroid hormone deficiency affects all body tissues, including multiple endocrine changes that alter growth hormones, corticotrophin, glucocorticoids, and gonadal function. In many countries, subfertility is an important problem affecting about 10–15% of all couples trying to conceive. Male subfertile factors have accounted for 25–30% of all cases in their studies. The aim of this study was to study the correlation between urinary iodine concentration (UIC) and semen quality of fertile male in China.Methods: semen and urine samples were collected from males who attended a survey for the reproductive physiological constants of male and female in China. All participants were fertile and they should be free from diseases of male reproductive system and thyroid related diseases. We studied the correlation between UIC and semen quality parameters in fertile males and the effect of iodine concentration on male reproduction. Participants were divided into six groups based on UIC. We measured semen parameters and UIC. Semen parameters or time-to-pregnancy (TTP) were analyzed by Spearman correlation, linear regression and multivariable logistic regression. Results: 1089 men were recruited in the study. The mean and median age of participants were 27.46±0.12 and 27±3.88 years, respectively. UIC of 274 (25.16%) men was lower than the UIC of WHO recommended. UIC of 405 men located in the region of WHO recommended. 62.35% of them were not located in the optimal region. Semen concentration and total sperm count were found to decrease when UIC increases when the UIC≥100 ug/L. Conclusions: A male with deficient UIC or excessive UIC has more risk of lower semen quality such as sperm concentration and total sperm count. In addition, if a male with deficient UIC or excessive UIC, his wife has longer TTP than the males who had normal UIC. Deficient UIC associated with lower semen quality and TTP than excessive UIC.

Effect of a phytoestrogen food supplement on reproductive health in normal males

2001 ◽  
Vol 100 (6) ◽  
pp. 613-618 ◽  
Author(s):  
Julie H. MITCHELL ◽  
Elizabeth CAWOOD ◽  
David KINNIBURGH ◽  
Anne PROVAN ◽  
Andrew R. COLLINS ◽  
...  
Keyword(s):  
Reproductive Health ◽  
Reproductive Tract ◽  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Human Sperm ◽  
Food Supplement ◽  
Testicular Volume ◽  
Semen Parameters

Animal studies and human intervention trials have demonstrated the cancer chemopreventive properties of plant phytoestrogens, and phytoestrogen supplements are now widely available ‘over-the-counter’. However, consumption of phytoestrogen-rich diets can cause impaired fertility and reproductive tract disorders in some animals and the apparent decline in human sperm quality over recent decades may be related to increased exposure to environmental endocrine disruptors. The present study determines the effects of a short-term phytoestrogen supplement on semen quality and serum sex steroid and gonadotrophin levels in human males. Healthy volunteers took a supplement containing 40 mg of isoflavones daily for 2 months and donated blood and semen samples monthly for 2 months before and 4 months after supplementation. Semen samples were analysed for ejaculate volume, sperm concentration, total sperm count, motility and morphology. Blood samples were analysed for sex hormone and gonadotrophin levels and phytoestrogen concentrations, and testicular volume was measured using an orchidometer. The phytoestrogen supplement increased plasma genistein and daidzein concentrations to approx. 1 µM and 0.5 µM respectively; yet, there was no observable effect on endocrine measurements, testicular volume or semen parameters over the study period. This is the first study to examine the effects of a phytoestrogen supplement on reproductive health in males. We conclude that the phytoestrogen dose consumed had no effect on semen quality.

scholarly journals Relation between BMI and Semen parameters in male infertility patients in west of Algeria

2020 ◽  
Vol 10 (2-s) ◽  
pp. 64-67
Author(s):  
Dalila Ferrag ◽  
Abbassia Demmouche ◽  
Charaf Khalloua Zine
Keyword(s):  
Body Mass Index ◽  
Male Infertility ◽  
Body Mass ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Infertile Men ◽  
The Mean ◽  
The Impact

Introduction: Body mass index BMI is a risk factor that influences semen quality and reduces male fertility. The aim of this study was to determine the impact of body mass index (BMI) on semen parameters in infertile men. Subject and method: A total of 446 infertile men, the study population was divided into four groups depending on their BMI , underweight (<18.5 kg/), normal weight (18.5-24.99 kg/m2 ), overweight 25-29.99 kg/m2), and obese >30.0 kg/.semen parameters (PH, volume, concentration ,total semen count ,vitality, morphology and motility ) were compared across the four BMI groups. Results: The mean of age was 41.91±6.39, the mean infertility duration was 4.92±3.28, 351(78.7٪) had primary infertility and 95(21.3٪) had secondary infertility. The mean BMI was 29.38± 4.85 and the most of patients 45.2٪ were obese. Conclusion: This study has found evidence of an association between BMI and semen parameters (Sperm concentration, Total sperm count, motility, and vitality) and no correlation between Semen volume, morphology and BMI. Keywords: Body mass index, male infertility, semen quality, west of Algeria

scholarly journals What is The Impact of Excessive Iodine and Semen Quality in Fertile Men of China: An Association Study

2021 ◽  
Author(s):  
Ning Wang ◽  
Fang Lv ◽  
Ge Yu ◽  
Cuige Shi ◽  
Shangming Wang ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Male Reproduction ◽  
Semen Parameters ◽  
Human Thyroid ◽  
Urinary Iodine Concentration ◽  
The Impact

Abstract Background: Iodine is an essential element for hormones synthesized by the human thyroid gland. Thyroid hormone deficiency affects all body tissues, including multiple endocrine changes that alter growth hormones, corticotrophin, glucocorticoids, and gonadal function. In many countries, subfertility is an important problem affecting about 10–15% of all couples trying to conceive. Male subfertile factors have accounted for 25–30% of all cases in their studies. The aim of this study was to study the correlation between urinary iodine concentration (UIC) and semen quality of fertile male in China.Methods: semen and urine samples were collected from males who attended a survey for the reproductive physiological constants of male and female in China. All participants were fertile and they should be free from diseases of male reproductive system and thyroid related diseases. We studied the correlation between UIC and semen quality parameters in fertile males and the effect of iodine concentration on male reproduction. Participants were divided into six groups based on UIC. We measured semen parameters and UIC. Semen parameters or time-to-pregnancy (TTP) were analyzed by Spearman correlation, linear regression and multivariable logistic regression. Results: 1089 men were recruited in the study. The mean and median age of participants were 27.46±0.12 and 27±3.88 years, respectively. UIC of 274 (25.16%) men was lower than the UIC of WHO recommended. UIC of 405 men located in the region of WHO recommended. 62.35% of them were not located in the optimal region. Semen concentration and total sperm count were found to decrease when UIC increases when the UIC≥100 ug/L. Conclusions: A male with deficient UIC or excessive UIC has more risk of lower semen quality such as sperm concentration and total sperm count. In addition, if a male with deficient UIC or excessive UIC, his wife has longer TTP than the males who had normal UIC. Deficient UIC associated with lower semen quality and TTP than excessive UIC.

scholarly journals Study of hormone levels and semen parameters in infertile patients and fertile controls from Batna

2017 ◽  
Vol 1 (2) ◽  
pp. 39-40
Author(s):  
Nour El Houda Bousnane ◽  
Ali Chennaf ◽  
Mouloud Yahia
Keyword(s):  
Male Infertility ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Public Health Problem ◽  
University Hospital ◽  
Semen Parameters ◽  
Endocrine Disorders ◽  
Major Public Health Problem ◽  
Infertile Men ◽  
The Impact

Background: Male infertility or the inability of a man to procreate is a major public health problem and is a leading cause of marital discord in countries such as Algeria. Endocrine disorders that can be associated with significant medical pathology remain an important factor to be considered in the etiology of male infertility, and those disorders are usually associated with alteration of sperm count or in severe cases with azoospermia. In this study, we are evaluating semen parameters and hormonal levels of patients with idiopathic male infertility and comparing their results with healthy fertile controls. Methods: We aim to study the impact of hormones; follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T) and prolactin (PRL) on idiopathic male fertility and their impact on semen parameters, we conducted a study on 71 male subjects with 39 infertile men and 32 fertile controls from the city of Batna (Algeria). Our study lasted six months and was conducted at the University Hospital of Batna and a private analysis laboratory. Results: The results of semen analysis allowed us to determine that the most common pathology in our population is OANTS with a percentage of 21.05% followed by NS and NT with 13.16%; results of the permocytogramme show a predominance of atypical forms of the head with a frequency of 39.21%. Regarding the hormone dosage, prolactin was the most disturbed hormone with an average value of (18 ± 6.221 ng/ml), which is almost pathologic; the other hormones showed some disturbances but to a lesser degree. The results of spermiologique parameters of infertile men compared with fertile controls showed highly significant differences (P≤O.OOO1) regarding motility, concentration vitality, and spermatozoa morphology. The comparison of results of hormones between the two groups revealed differences in LH and prolactin levels; no differences were found regarding FSH and testosterones. Concerning the relationship between hormones and spermiologiques parameters, positive correlations were found between (LH and sperm concentration) (testosterone and sperm concentration), and, finally, a strong correlation was found between the levels of prolactin and the anomalies of intermediate piece of spermatozoa. Conclusion: This study showed that hormonal disorders are not a common cause of male infertility in our study population. It further showed the relative frequencies of the various semen abnormalities during the study period. Also, we found associations between altered semen parameters and pathological levels of some hormones; however, a complementary study with a more subjects is needed.

scholarly journals Semen quality pattern and age threshold: a retrospective cross-sectional study of 71,623 infertile men in China, between 2011 and 2017

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
W. N. Li ◽  
M. M. Jia ◽  
Y. Q. Peng ◽  
R. Ding ◽  
L. Q. Fan ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Cross Sectional Study ◽  
Semen Parameters ◽  
Sectional Study ◽  
Joinpoint Regression ◽  
Cross Sectional ◽  
Progressive Motility ◽  
Infertile Men

Abstract Background The aim of this study was to provide information on the semen quality pattern of infertile men and age thresholds for semen parameters in China. Methods This was a retrospective cross-sectional study investigating 71,623 infertile men from the Reproductive and Genetic Hospital of CITIC Xiangya in Hunan, China, from 2011 to 2017. The Kruskal-Wallis test, Mann-Kendall test, linear regression model and joinpoint regression were used. Results Although erratic changes were observed in the median semen parameters (sperm concentration 40.1–52.1 × 106/ml, total sperm count 117.8–153.1 × 106, sperm progressive motility 33.4–38.1%) during the 7 years of observation, no significant decrease in semen quality was found, and 47.88% of infertile men showed normal semen parameters according to the World Health Organization (WHO) criteria. According to the joinpoint regression analysis, sperm progressive motility appeared to decrease earlier than the sperm concentration and total sperm count (at 28, 58, and 42 years of age, respectively). Conclusions There is no evidence of a deterioration in semen quality among infertile men in Hunan, China. Semen parameters decreased with increasing age, with turning points noted at different ages. Semen parameters are not absolute evidence for the assessment of male fertility potential. Therefore, we believe that, among semen parameters, the sperm concentration is the best predictor of fertility for ART, followed by motility. Decreased sperm motility may affect natural pregnancy, but it is not necessary for successful IVF.

scholarly journals The Association Between Abstinence Period and Semen Parameters: Results in Normal Samples and Different Sperm Pathology

2021 ◽  
Author(s):  
Min Xie ◽  
Silvan Hämmerli ◽  
Kerstin Blickenstorfer ◽  
Brigitte Leeners
Keyword(s):  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Sexual Abstinence ◽  
Normal Morphology ◽  
Few Data ◽  
Total Motile Sperm Count ◽  
Abstinence Period

Abstract Purpose: The length of sexual abstinence seems to influence sperm quality. However, few data on the relevance of abstinence time in pathological sperm samples are available. With our study, we look for associations of abstinence length and semen quality. Methods: We studied semen samples from 4423 men undergoing fertility evaluation. Sperm concentration, percentage of progressively motile spermatozoa, total motile sperm count, percentage of spermatozoa with normal morphology, were compared after each day and 0-2, 3-7 and >7 days of abstinence. Results: We found that a longer abstinence time was related to higher sperm concentration in normal semen samples (P<0.001) and in semen samples with any sperm pathology (P<0.001, P=0.004) with the exception of oligozoospermia (P=0.125). Longer abstinence time was also associated with significantly reduced progressive motility in normal samples (P<0.001) and in cases of teratozoospermia (P<0.001). In normal samples a higher percentage of sperm were morphologically normal after a shorter abstinence period (P=0.03); in oligoasthenoteratozoospermia (OAT) samples, this was the case after a longer abstinence period (P=0.013). Conclusion: A longer abstinence time is associated with higher sperm concentration, whereas sperm motility is optimal after shorter abstinence times; results on morphology are controversial. The recommendation on abstinence time needs to be adjusted in relation to the parameter that needs to be improved.

scholarly journals The Impact of Radiofrequency Waves on Male Infertility: A Systematic Review

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Leili Darvish ◽  
Azadeh Amraee ◽  
Marjan Akhavan Amjadi ◽  
Zahra Atarodi Kashani ◽  
Masoumeh Ghazanfarpour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Male Infertility ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Membrane Integrity ◽  
Semen Parameters ◽  
Cochrane Library ◽  
Negative Effects ◽  
The Impact

Context: As the use of cellphones and other electronic devices increases, concerns about the possible effect of radiofrequency waves on health are growing. Long-term use of the cellphone may have negative effects on sperm quality. Objectives: The purpose of this research was to examine men's infertility due to the effect of radiofrequency waves. Methods: In this systematic review, language restrictions were not considered in searching the databases. Cochrane Library, Google Scholar, PubMed, EMBASE, ProQuest, CINAHL, Science Direct, MEDLINE, and Scopus were used to obtain the data from them. All data were scanned from the year 2000 until 2019. Papers selected for retrieval were evaluated by the Newcastle-Ottawa and CONSORT scales. Results: A total of 14 articles that met the inclusion criteria were ultimately assessed. Motile sperm, sperm vitality and membrane integrity, morphology, volume, total sperm count, sperm concentration, and sperm fertility were found to be influenced by radiofrequency waves. Conclusions: The results showed that RF has detrimental effects on semen parameters and due to an increase in RF wave use currently and its role in male infertility, giving information to men about adverse complications of RF is necessary. Further studies are needed to design the less harmful devices.

scholarly journals The Impact of Intense Exercise on Semen Quality

2016 ◽  
Vol 11 (3) ◽  
pp. 654-662 ◽  
Author(s):  
Paweł Jóźków ◽  
Marco Rossato
Keyword(s):  
Physical Activity ◽  
Semen Quality ◽  
Sperm Count ◽  
Semen Analysis ◽  
Semen Parameters ◽  
Male Factor ◽  
Recreational Athletes ◽  
Increasing Demand ◽  
Male Reproductive Health ◽  
The Impact

With expanding knowledge on the health benefits of exercise, there is an increasing demand for information on the andrological consequences of participating in sports. These consequences are especially important in the context of infertility problems worldwide. The so-called “male factor” is reported in up to 50% of couples having trouble with conception. The answer to the question, “Is physical activity good for male reproductive health?” is not straightforward. A number of studies have suggested that significant changes in semen parameters may occur due to sports training of certain types, intensities, and durations. The changes to these parameters vary in scope, direction, and magnitude. Findings in recreational athletes have also differed from those in professional athletes. This review of the current literature suggests that intense physical activity may affect the semen concentration, as well as the number of motile and morphologically normal spermatozoa. Training at higher intensities and with increased loads seems to be associated with more profound changes in semen quality. In recreational athletes, exercise has either a positive or neutral effect on semen parameters. Due to many limitations (e.g., global sperm count trends, concerns about the quality control of sperm evaluations, and new standards for semen analysis), comparisons among historical data and their interpretation are difficult.

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