Cross Cultural Adaptation and Validation of Nigerian (Igbo) Version of the Older People’s Quality of Life Questionnaire (OPQOL-35): a Validation Study

Abstract Background Quality of life (QoL) has been revealed to determine an older adult’s assessment of successful and active ageing; and to evaluate various range of health and social care interventions. Most QoL assessment tools were developed for use in developed countries. This may not be suitable for developing nations such as Nigeria. There is need for availability of culture- and environment- specific tools for assessment of QoL. This study was therefore designed to cross-culturally adapt the OPQOL-35 into Igbo language, and determine its reliability and validity. Methods The original English OPQOL-35 (E-OPQOL-35) was translated into Igbo language, synthesized, back translated, and subsequently subjected to expert panel review, pre-testing and cognitive debriefing interview, following the American Academy of Orthopaedic Surgeons’ guideline. The final Igbo version (I-OPQOL-35) was tested for internal consistency, concurrent and structural validities in a cross-sectional study of 115 consenting apparently healthy older adults (54.8% females) that were recruited from conveniently selected local government areas in Enugu State, at 0.05 level of significance. Results The OPQOL-35 was cross-culturally adapted to Igbo with all its 35 items retained. The Spearman correlation coefficients between the participants’ domain and total scores on the I-OPQOL-35 and E-OPQOL-35 (rho = 0.92-1.00) were excellent. The Mann Whitney-U test revealed no significant difference between corresponding scores in the E-OPQOL-35 and I-OPQOL-35 (p = 0.65-0.94). The internal consistency coefficient of the I-OPQOL-35 was 0.78. Conclusions The I-OPQOL-35 is therefore a valid and reliable instrument for the assessment of QoL among Igbo older adults in Nigeria.

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Translation and Validation of the Thai Version of the Wisconsin Quality of Life Questionnaire (TH WISQoL) for Kidney Stone Patients

Journal of the Medical Association of Thailand ◽

10.35755/jmedassocthai.2020.11.11450 ◽

2020 ◽

Vol 103 (11) ◽

pp. 1194-1199

Keyword(s):

Quality Of Life ◽

Internal Consistency ◽

Kidney Stone ◽

Convergent Validity ◽

Large Scale ◽

Short Form ◽

Outcome Measurement ◽

Life Questionnaire ◽

Sf 36

Objective: To develop and validate a Thai version of the Wisconsin Quality of Life (TH WISQoL) Questionnaire. Materials and Methods: The authors developed the TH WISQoL Questionnaire based on a standard multi-step process. Subsequently, the authors recruited patients with kidney stone and requested them to complete the TH WISQoL and a validated Thai version of the 36-Item Short Form Survey (TH SF-36). The authors calculated the internal consistency and interdomain correlation of TH WISQoL and compared the convergent validity between the two instruments. Results: Thirty kidney stone patients completed the TH WISQoL and the TH SF-36. The TH WISQoL showed acceptable internal consistency for all domains (Cronbach’s alpha 0.768 to 0.909). Interdomain correlation was high for most domains (r=0.698 to 0.779), except for the correlation between Vitality and Disease domains, which showed a moderate correlation (r=0.575). For convergent validity, TH WISQoL demonstrated a good overall correlation to TH SF-36, (r=0.796, p<0.05). Conclusion: The TH WISQoL is valid and reliable for evaluating the quality of life of Thai patients with kidney stone. A further large-scale multi-center study is warranted to confirm its applicability in Thailand. Keywords: Quality of life, Kidney stone, Validation, Outcome measurement

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COMPARISON OF THE QUALITY OF LIFE OF PATIENTS IN THE LOCALY ADVANCED BREAST CANCER FORMS AFTER SYSTEM AND INTRALYMPHATIC POLYCHEMOTHERAPY

EUREKA Health Sciences ◽

10.21303/2504-5679.2018.00693 ◽

2018 ◽

Vol 4 ◽

pp. 3-13

Author(s):

Yuriy Dumanskiy ◽

Oleksandr Bondar ◽

Oleksandr Tkachenko ◽

Evhenii Stoliachuk ◽

Vasilii Ermakov

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Locally Advanced ◽

Developed Countries ◽

Control Group ◽

Preoperative Treatment ◽

Discrete Elements ◽

Important Indicator ◽

Significant Difference

In recent years, breast cancer (BC) is the most common cancer pathology and the most common cause of disability among women in developed countries. Finding the most effective ways of interaction between the patient and the doctor creates the preconditions for the necessary analysis of the treatment process from an objective and subjective point of view. Therefore, an important indicator to be taken into account is the quality of life of a patient. To compare the indicators of a comprehensive assessment of the quality of life of patients to the adverse locally advanced forms (LA) of breast cancer before and after systemic intravenous polychemotherapy (SPCTx) and selective endolymphatic polychemotherapy (ELPCTx) in neoadjuvant mode. The study was conducted on the basis of a random analysis of outpatient cards from 112 patients with LA BC T4A-DN0-3M0 who received a comprehensive antitumor treatment on the basis of the Donetsk regional antitumor center and the University Clinic of the Odessa National Medical University from 2000 to 2017, which was proposed a questionnaire at various stages of preoperative treatment. The first (control) group consisted of 65 patients (58 %) with inoperable forms of LA BC, which was performed in neoadjuvant mode by SPCTx. The second (study group) included 47 patients (42 %) with inoperable forms of LA BC, which was performed as a neoadjuvant course ELPCTx. According to the integral indicators of quality of life and quality of health between patients in the control and study groups, there was no statistically significant difference. In a detailed analysis of the indicators of symptomatic scales, the difference between the groups did not exceed the critical. Based on the results of a study conducted among patients receiving endolymphatic chemotherapy in a neoadjuvant mode, the subjective evaluations of treatment in absolute numbers have better reference values without statistical superiority. The study of the integrative indicator of quality of life and its discrete elements is an ergonomic and economical means of heuristic assessment of the health of patients in order to further develop more rational and convenient ways of solving urgent issues of modern oncology by increasing compliance and finding a compromise between the physician and the patient.

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Evaluation of the efficacy of hearing aids in older adults: a multiparametric longitudinal study protocol

BMC Geriatrics ◽

10.1186/s12877-021-02033-z ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Domenico Cuda ◽

Sara Ghiselli ◽

Alessandra Murri

Keyword(s):

Quality Of Life ◽

Older Adults ◽

Speech Perception ◽

Hearing Aids ◽

Assessment Tools ◽

Elderly Subjects ◽

Single Subject ◽

Measurement Tools ◽

First Time

Abstract Background Prevalence of hearing loss increases with age. Its estimated prevalence is 40–50 % in people over 75 years of age. Recent studies agree that declinein hearing threshold contribute to deterioration in sociality, sensitivity, cognition, and quality of life for elderly subjects. The aim of the study presented in this paper is to verify whether or not rehabilitation using first time applied Hearing Aids (HA) in a cohort of old people with hearing impairment improves both speech perception in a noisy environment over time and the overall health-related quality of life. Methods The monocentric, prospective, repeated measurements, single-subject, clinical observational study is to recruit 100 older adults, first-time HA recipients (≥ 65 years).The evaluation protocol is designed to analyze changes in specific measurement tools a year after the first HA usage in comparison with the evaluation before HA fitting. Evaluations will consist of multiparametric details collected through self-report questionnaires completed by the recipients and a series of commonly used audiometric measures and geriatric assessment tools. The primary indicator of changes in speech perception in noise to be used is the Italian version of Oldenburg Satz (OLSA) test whereas the indicator of changes in overall quality of life will be the Assessment of Quality of Life (AQoL) and Hearing Handicap Inventory for the Elderly (HHIE) questionnaires. The Montreal Cognitive Assessment (MoCA) will help in screening the cognitive state of the subjects. Discussion The protocol is designed to make use of measurement tools that have already been applied to the hearing-impaired population in order to compare the effects of HA rehabilitation in the older adults immediately before first HA usage (Pre) and after 1 year of experience (Post). This broad approach will lead to a greater understanding of how useful hearing influences the quality of life in older individuals, and therefore improves potentials for healthy aging. The data is to be analyzed by using an intrasubject endpoint comparison. Outcomes will be described and analyzed in detail. Trial registration This research was retrospectively registered underno. NCT04333043at ClinicalTrials.gov (http://www.clinicaltrials.gov/) on the 26 March 2020. This research has been registered with the Ethics Committee of the Area Vasta Emilia Nord under number 104, date of approval 17/07/2017.

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Polish Adaptation of the Italian Spine Youth Quality of Life Questionnaire

Journal of Clinical Medicine ◽

10.3390/jcm10102081 ◽

2021 ◽

Vol 10 (10) ◽

pp. 2081

Author(s):

Edyta Kinel ◽

Krzysztof Korbel ◽

Piotr Janusz ◽

Mateusz Kozinoga ◽

Dariusz Czaprowski ◽

...

Keyword(s):

Quality Of Life ◽

Internal Consistency ◽

Spinal Deformity ◽

Cultural Adaptation ◽

Life Questionnaire ◽

Alpha Coefficient ◽

Cronbach’S Alpha ◽

Quality Of Life Questionnaire ◽

Cronbach's Alpha

The study aimed to carry on the process of the cultural adaptation of the Italian Spine Youth Quality of Life Questionnaire (ISYQOL) into Polish (ISYQOL-PL). The a priori hypothesis was: the ISYQOL-PL questionnaire is reliable and appropriate for adolescents with a spinal deformity. Fifty-six adolescents (mean age 13.8 ± 1.9) with idiopathic scoliosis (AIS) with a mean Cobb angle 29.1 (±9.7) and two with Scheuermann juvenile kyphosis (SJK) with a kyphosis angle 67.5 (±17.7) degrees were enrolled. All patients had been wearing a corrective TLSO brace for an average duration of 2.3 (±1.8) years. The Institutional Review Board approved the study. The cross-cultural adaptation of the ISYQOL-PL was performed following the guidelines set up by the International Quality of Life Assessment Project. The reliability was assessed using internal consistency (the Cronbach’s alpha coefficient) and test–retest reliability (intraclass correlation coefficient ICC2.1, CI = 95%); moreover, floor and ceiling effects were calculated. The internal consistency was satisfactory (Cronbach’s alpha coefficient 0.8). The test–retest revealed high reliability with the value of ICC2.1 for the entire group 0.90, CI (0.84 to 0.94). There was neither floor nor ceiling effect for the ISYQOL-PL overall score. The ISYQOL-PL is reliable and can be used in adolescents with spinal deformity.

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Effectiveness analysis of the new method of antireflux surgery in patients with hiatal hernia

Acta Medica Leopoliensia ◽

10.25040/aml2020.04.050 ◽

2020 ◽

Vol 26 (4) ◽

pp. 50-55

Author(s):

A.R. Stasyshyn ◽

◽

A.A. Hurayevskyy ◽

Yu.Y. Holyk ◽

◽

...

Keyword(s):

Quality Of Life ◽

Los Angeles ◽

Hiatal Hernia ◽

Antireflux Surgery ◽

New Method ◽

Life Questionnaire ◽

Post Surgery ◽

Group I ◽

Significant Difference

Aim. To analyze the effectiveness of a new method of antireflux surgery in patients with hiatal hernia. Materials and Methods. The results of treatment of 157 patients with hiatal hernia from 2016 to 2020 are analyzed. The patients were divided into 3 groups: group I, N=59, underwent laparoscopic antireflux operation modified by the authors (Patent of Ukraine № 59772); group II (N=77), underwent laparoscopic Nissen fundoplication; and group III (N=21) - laparoscopic Toupet fundoplication. Results and Discussion. At 36 months post-surgery follow-up, there was a statistically significant difference in favor of group I on the average scores of the visual analog scale for reflux symptoms, dysphagia and extraesophageal symptoms; the average quality of life questionnaire scores; the average DeMeester index; distribution of the patients by satisfaction; distribution of the patients by degree of reflux esophagitis according to the Los Angeles classification; and distribution by gas-bloat syndrome. Conclusions. Clinical application of the developed new method of laparoscopic surgery for hiatal hernia reduces the number of relapses and complications after surgery, and improves the quality of life of patients. Key words: hiatal hernia, antireflux surgery, new methods of treatment

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Visitation and quality of life among older adults in jail

International Journal of Prisoner Health ◽

10.1108/ijph-06-2021-0058 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Stephanie Grace Prost ◽

Meghan A. Novisky

Keyword(s):

Quality Of Life ◽

Older Adults ◽

Social Relationships ◽

Developmental Theory ◽

Cross Sectional ◽

Younger Adults ◽

Content Type ◽

Significant Difference ◽

The Relationship

Purpose The purpose of this paper aims to examine differences in measures of and relationships between visitation and quality of life (QOL) among older and younger jailed adults. The authors also explored the contribution of visitation to QOL among adults in this setting. The authors anticipated fewer visits and lower QOL among older adults. Framed by psychosocial developmental theory, the authors also anticipated a larger effect in the relationship between visitation and QOL among older rather than younger adults and that visitation would contribute most readily to psychological QOL. Design/methodology/approach Cross-sectional data from a large US jail were used (n = 264). The authors described the sample regarding visitation and QOL measures among older (≥45) and younger adults (≤44) and examined differences in measures of and relationships between visitation and QOL using independent sample t-tests and bivariate analyses. The authors explored the contribution of visitation to psychological, social relationships, physical and environmental QOL among jailed adults using hierarchical multiple linear regression. Findings Older adults had fewer family visits and lower physical QOL than younger adults, disparities were moderate in effect (d range = 0.33–0.35). A significant difference also emerged between groups regarding the visitation and environmental QOL relationship (z = 1.66, p <0.05). Visitation contributed to variation in physical and social relationships QOL among jailed adults (Beta range = 0.19–0.24). Originality/value Limited research exists among jailed older adults and scholars have yet to examine the relationship between visitation and QOL among persons in these settings.

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The Development of a Quality of Life Scale for Informal Carers for Older Adults

Gerontology and Geriatric Medicine ◽

10.1177/2333721420920424 ◽

2020 ◽

Vol 6 ◽

pp. 233372142092042

Author(s):

John Maltby ◽

Eef Hogervorst ◽

Blossom Stephan ◽

Xu Sun ◽

Pinyan Tang ◽

...

Keyword(s):

Quality Of Life ◽

Older Adults ◽

Informal Care ◽

Personal Growth ◽

Life Questionnaire ◽

Confirmatory Factor Analyses ◽

Quality Of Life Scale ◽

Life Scale ◽

Informal Carers

Background: The aim of the study was to develop a multidimensional quality of life instrument suitable for use among individuals across cultures who have an informal care role for older persons. Methods: Participants were informal carers of older adults in the United Kingdom ( n = 308), United States ( n = 164), and China ( n = 131). We carried out exploratory and confirmatory factor analyses of 61 items derived from the eight-factor Adult Carers Quality of Life Questionnaire with newly added items to define both traditional and nontraditional informal care roles. Results: Findings suggest a 24-item quality of life scale with a six-factor structure to caring for older adults that assesses (a) exhaustion, (b) adoption of a traditional carer role, (c) personal growth, (d) management and performance, (e) level of support, and (f) financial matters. Conclusion: We present a new scale to assess the multidimensional aspects of quality of life among those caring for older adults.

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Validation of the French version of the Wisconsin Quality of Life (WISQOL) questionnaire for patients with urolithiasis

Canadian Urological Association Journal ◽

10.5489/cuaj.6552 ◽

2020 ◽

Vol 15 (4) ◽

Author(s):

Naeem Bhojani ◽

Ghizlane Moussaoui ◽

David-Dan Nguyen ◽

Mei Juan Trudel ◽

Garo-Shant Topouzian ◽

...

Keyword(s):

Quality Of Life ◽

Internal Consistency ◽

Tertiary Care ◽

Rank Correlation ◽

French Version ◽

Spearman’S Rank Correlation ◽

Significant Difference ◽

Back Translation ◽

One Way Anova

Introduction: The Wisconsin Stone Quality of Life (WISQOL) questionnaire has been recently developed to objectively assess QOL in patients with urolithiasis. However, French version of the questionnaire was lacking. Therefore, the aim of the present study was to develop and validate the French version of this tool. Methods: The French version of the WISQOL (F-WISQOL) was developed in a multi-step process involving primary translation, back-translation and pilot testing amongst a group of patients (n=12). Urolithiasis patients from two tertiary care institutions were recruited into this study and completed 3 questionnaires: Perceived Stress Scale-10, medical history form and either the WISQOL or F-WISQOL. Internal consistency was assessed using Cronbach’s α and inter-domain associations were evaluated using Spearman’s rank correlation (r). One-way ANOVA was used to compare scores from the two groups (WISQOL and F-WISQOL). Results: A total of 210 patients were enrolled in this study; 68 in the WISQOL group and 148 in the F-WISQOL group. Internal consistency was high for all domains in both groups (F-WISQOL: 0.924-0.970; WISQOL: 0.888-0.965). No statistically significant difference was found between the two groups’ scores. Inter-domain association, measured by Spearman correlation, was moderate to very strong between all of the domains in the F-WISQOL. Values ranged from r=0.676-0.915, with acceptable correlation between D1, D2 and D3, but weaker correlation between D4 (vitality) and the 3 other domains r=0.676-0.729. Conclusions: In the present study, the French version of the WISQOL questionnaire (F-WISQOL) was validated at two academic institutions.

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Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer.

Journal of Clinical Oncology ◽

10.1200/jco.1995.13.9.2317 ◽

1995 ◽

Vol 13 (9) ◽

pp. 2317-2323 ◽

Cited By ~ 55

Author(s):

M Hill ◽

A Norman ◽

D Cunningham ◽

M Findlay ◽

M Watson ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Advanced Colorectal Cancer ◽

Symptomatic Improvement ◽

Interferon Alfa ◽

Life Questionnaire ◽

European Organization ◽

Significant Difference ◽

Venous Infusion

PURPOSE The aim of this study was to investigate the effects of adding interferon alfa-2b (IFN) to protracted venous infusion fluorouracil (PVI 5-FU) from the start of treatment in patients with advanced colorectal cancer. PATIENTS AND METHODS Patients who attended our unit with histologically confirmed advanced colorectal cancer were randomized to receive either PVI 5-FU 300 mg/m2/d via Hickman line, and IFN 5 MU subcutaneously three times weekly, or PVI 5-FU alone. Treatment was given for a maximum of two 10-week blocks, with a 2-week gap for reassessment of all parameters. Quality of life (QL) was measured by the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30) pretreatment and every 6 weeks thereafter. RESULTS A total of 160 patients were randomized, with 155 eligible for assessment. Radiologic response was observed in 43 patients (28%): 17 of 77 (22%) in the 5-FU-plus-IFN arm (all partial responses [PRs]) and 26 of 78 (33%) in the 5-FU-alone group (complete responses [CRs] and 22 PRs) (difference not significant). Symptomatic improvement occurred in the majority of patients, and equally in both arms: 61% to 80% depending on the symptom. There was no significant difference between the two groups in failure-free survival (median, 161 v 193 days) or overall survival (median, 328 v 357 days). However, patients who received IFN did experience significantly more toxicity in the form of leukopenia (P = .001), neutropenia (P = .04), mucositis (P = .008), and alopecia (P = .0002). There were no toxic deaths and few notable differences in QL between the two arms. CONCLUSION This study confirms that PVI 5-FU is effective in treating the symptoms associated with metastatic colorectal carcinoma, with only mild to moderate toxicity and maintenance of QL. IFN 5 MU three times weekly does not enhance these palliative benefits.

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Prolonged clinical remission and low disease activity statuses are associated with better quality of life in systemic lupus erythematosus

Lupus ◽

10.1177/0961203319862614 ◽

2019 ◽

Vol 28 (10) ◽

pp. 1189-1196 ◽

Cited By ~ 5

Author(s):

N Poomsalood ◽

P Narongroeknawin ◽

S Chaiamnuay ◽

P Asavatanabodee ◽

R Pakchotanon

Keyword(s):

Quality Of Life ◽

Systemic Lupus Erythematosus ◽

Disease Activity ◽

Lupus Erythematosus ◽

Clinical Remission ◽

Life Questionnaire ◽

Systemic Lupus ◽

Low Disease Activity ◽

Significant Difference

Objective The objective of this study was to determine the association between disease activity status and health-related quality of life (HRQoL) in systemic lupus erythematosus (SLE) patients. Methods SLE patients in an out-patient clinic during the previous 12 months were included in the study. The Systemic Lupus Erythematosus-specific Quality-of-Life questionnaire (SLEQoL) was administered at the last visit. Disease activity status was determined retrospectively during the previous year. The categories of disease activity status were defined as: clinical remission (CR): clinical quiescent disease according to Systemic Lupus Erythematosus Disease Activity Index 2000, prednisolone ≤ 5 mg/day; low disease activity (LDA): SLEDAI-2K (without serological domain) ≤ 2, prednisolone ≤ 7.5 mg/day; and non-optimally controlled status: for those who were not in CR/LDA. Immunosuppressive drugs (maintenance dose) and antimalarials were allowed. Prolonged CR or LDA was defined as those with sustained CR or LDA for at least one year. The association between disease activity status and HRQoL was assessed by using regression analysis adjusting for other covariates. Results Of 237 SLE patients, 100 patients (42.2%) achieved prolonged CR, 46 patients (19.4%) achieved prolonged LDA and 91 patients (38.4%) were not in CR/LDA. Non-CR/LDA patients had significantly higher total SLEQoL score and in all domains compared to CR/LDA patients. No significant difference in SLEQoL domain scores was found between CR and LDA groups. Multivariable analysis revealed that non-CR/LDA was positively associated with SLEQoL score compared with CR/LDA (β 20.02, 95% confidence interval (CI) 6.81–33.23, p < 0.003). Moreover, non-CR/LDA was at a higher risk of impaired QoL (SLEQoL score > 80) compared with CR (hazard ratio 3.8; 95% CI 1.82–7.95; p < 0.001). However, there was no significant difference between CR and LDA in terms of SLEQoL score or impaired QoL. Other factors associated with higher SLEQoL score were damage index (β 9.51, 95% CI 3.52–15.49, p = 0.002) and anemia (β 24.99, 95% CI 5.71–44.27, p = 0.01). Conclusion Prolonged CR and LDA are associated with better HRQoL in SLE patients and have a comparable effect. Prolonged CR or optional LDA may be used as the treatment goal of a treat to target approach in SLE.

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