scholarly journals Application of Mediastinal Drainage Tube in Intrathoracic Esophageal Anastomotic Leakage for Early Diagnosis and Effective Treatment: A Retrospective Study

2020 ◽  
Author(s):  
Hainong Ma ◽  
Xu Song ◽  
Jie Li ◽  
Guofang Zhao
Keyword(s):  
Early Diagnosis ◽  
Anastomotic Leakage ◽  
Esophageal Resection ◽  
Drainage Tube ◽  
Control Group ◽  
Common Symptom ◽  
Pleural Drainage ◽  
Significant Difference ◽  
Mediastinal Drainage ◽  
Almost All

Abstract Background: Intrathoracic esophageal anastomotic leakage (AL) is one of the most fatal complications after esophagectomy. In this study, we tried to place an additional drainage tube in esophagus bed and evaluate its effect in early diagnosis and treatment of AL.Methods: From January 2010 to August 2020, a total of 312 patients, who suffered from esophageal or cardia carcinoma, underwent esophageal resection with intrathoracic esophagogastric anastomosis. Among them, we identified 138 patients with only one pleural drainage tube as “Control Group” and 174 patients with a pleural drainage tube and an additional mediastinal drainage tube (MDT) as “Tube Group”. The incidence of postoperative AL, time to diagnosis, time to recovery, and patient outcome were analyzed.Results: There were no significant differences in the AL rate (P = 0.837) and postoperative pain between two groups. However, in the Tube Group, almost all the patients were definitely diagnosed prior to the appearance of hyperpyrexia, which was regarded as the earliest and most common symptom after AL. Moreover, in the Tube Group, there was significant decrease in the incidence of uncurable fistula, which required re-operation or variable treatments under gastroscopy, when compared to the Control Group (P = 0.032). Finally, patients in the Tube Group were associated with reduced post AL hospital day (P = 0.015) and lower mortality, although there was no significant difference (P = 0.188), than in the Control Group.Conclusions: Placement of a MDT can not prevent the AL, but it is an effective method to diagnose AL earlier and facilitate the fistula healing and patient recovery.

scholarly journals Application of mediastinal drainage tube in intrathoracic esophageal anastomotic leakage for early diagnosis and effective treatment: a retrospective study

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Hainong Ma ◽  
Xu Song ◽  
Jie Li ◽  
Guofang Zhao
Keyword(s):  
Early Diagnosis ◽  
Anastomotic Leakage ◽  
Esophageal Resection ◽  
Drainage Tube ◽  
Control Group ◽  
Common Symptom ◽  
Pleural Drainage ◽  
Mediastinal Drainage ◽  
Group A ◽  
Almost All

Abstract Background Intrathoracic esophageal anastomotic leakage (AL) is one of the most fatal complications after esophagectomy. In this study, we placed an additional drainage tube in the esophagus bed and evaluated its effect in early diagnosis and treatment of AL. Methods From January 2010 to August 2020, 312 patients with esophageal or cardia carcinoma underwent esophageal resection with intrathoracic esophagogastric anastomosis. A total of 138 patients with only one pleural drainage tube were divided into the “Control Group” and 174 patients with a pleural drainage tube and an additional mediastinal drainage tube (MDT) were divided into the “Tube Group”. For all patients, the incidence of postoperative AL, the time to diagnosis, time to recovery, and patient outcome were analyzed. Results No significant differences were observed in the AL rate (P = 0.837) and postoperative pain between two groups. However, in the Tube Group, almost all the patients were diagnosed prior to the appearance of hyperpyrexia, which was considered as the earliest and most common symptom after AL. In the Tube Group, a significant decrease was observed in the incidence of incurable fistula, which required re-operation or variable treatments under gastroscopy when compared to the Control Group (P = 0.032). Finally, patients in the Tube Group showed reduced post AL hospital day (P = 0.015) and a lower mortality, however, when compared to the Control Group, no significant differences were observed (P = 0.188). Conclusions Placement of an MDT does not prevent AL, but it is an effective approach for earlier diagnosis of AL and facilitates fistula healing and patient recovery.

scholarly journals Impact of child labor in stone quarries on his health status in El- Minia city

2016 ◽  
Vol 5 (2) ◽  
pp. 167
Author(s):  
Naglaa Saad Abd EL-Aty ◽  
Nazek Ibrahim Abd EL-Ghany ◽  
Farag Mohammed Moftah ◽  
Shokria Adly Labeeb ◽  
Awatef Abdel-Razak Mohammed
Keyword(s):  
Health Status ◽  
Child Labor ◽  
Family Income ◽  
Developed Countries ◽  
Control Group ◽  
Working Children ◽  
Significant Difference ◽  
Assessment Sheet ◽  
Almost All ◽  
Minia City

Background: Child labor today represents the largest single cause of child abuse across the global. Most of it takes place in economically less developed countries and much is hidden.Objectives: The aims of this study were to found out the nature and impact of child labor in the stone quarries on his health status and assess the work hazards associated with these concern.Methods Design: A descriptive comparative design was used .Setting: at stone quarries in El-Minia city and two Governmental schools (primary and preparatory).Sample: Study consisted sample of two groups: two hundred working children (studied group) and three hundred school children as control group.Tools: Three tools were developed and utilized. Socio-demographic characteristics, assessment sheet, and Observation check list.Results: It was found that the mean age studied group was 13.0± 1.2, compared to 12.0± 1.2for control group. More than half of studied group of studied group were working for the need to money and to share in family income. About two third of studied group exposed to different types of injuries during work in quarry. There was statistical significant difference between studied and control group groups regarding body mass index physical assessment and bad habits. Also the results of this study explored that most of studied group exposed to all items of work hazards.Conclusion: It can be concluded that almost all working children in stone quarries were facing much health complains and working hazards.Recommendations: Quarries owners should provide all working children with appropriate protective measures and trained them on methods of protecting themselves from work hazards.

scholarly journals Effect of Auricular Acupressure on Uremic Pruritus in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Cui-na Yan ◽  
Wei-guo Yao ◽  
Yi-jie Bao ◽  
Xiao-jing Shi ◽  
Hui Yu ◽  
...  
Keyword(s):  
Intervention Group ◽  
Maintenance Hemodialysis ◽  
Control Group ◽  
Common Symptom ◽  
Uremic Pruritus ◽  
Auricular Acupressure ◽  
Significant Difference ◽  
Vas Scores ◽  
And Control

Background. Uremic pruritus (UP) is a common symptom in patients undergoing maintenance hemodialysis for end-stage renal disease (ESRD).Objective. To determine the clinical efficacy of auricular acupressure therapy on pruritus in hemodialysis patients and to explore possible underlying mechanisms.Methods. Patients receiving maintenance hemodialysis at a referral medical center were recruited and assigned to intervention (n=32) and control (n=30) groups. The intervention group underwent auricular acupressure treatment three times a week for six weeks. Auricular acupressure was not applied to patients in the control group. However, tape withoutVaccariaseeds was applied to the same six auricular acupoints as the intervention group. Pruritus scores were assessed using VAS scores, and enzyme-linked immunosorbent assays (ELISA) were used to measure levels of other possible contributory biochemical factors.Results. There was a significant difference in mean VAS scores between the postintervention and control groups during follow-up (3.844 ± 1.687 versus 5.567 ± 2.285,F=22.32,P<0.0001). Compared to the control group, serum histamine levels in the postintervention group at the six-week follow-up had decreased significantly (F=5.01,P=0.0290).Conclusion. Our findings suggest that auricular acupressure may be a useful treatment in the multidisciplinary management of UP in ESRD patients.

scholarly journals Omega-3 Fatty Acids plus Vitamin E Cosupplementation versus Vitamin E in Fibrocystic Breast Patient with Mastalgia: A Randomized Controlled Trial

2021 ◽  
Vol 9 (B) ◽  
pp. 116-121
Author(s):  
Marwa Mostafa Ahmed ◽  
Eman Ahmed Rushdy ◽  
Dalia Ahmed Aboul Azm ◽  
Rehab Mohamed Sabry ◽  
Heba Galal El Nahas
Keyword(s):  
Randomized Controlled Trial ◽  
Vitamin E ◽  
Pain Score ◽  
Controlled Trial ◽  
Control Group ◽  
Common Symptom ◽  
Omega 3 ◽  
Negative Effects ◽  
Randomized Controlled ◽  
Significant Difference

BACKGROUND: Fibrocystic changes (FCCs) of the breast are a common breast condition. Mastalgia is the most common symptom of FCC; it usually causes fear of breast cancer and has negative effects on the quality of life. AIM: The objective of the research was to establish the effect of cosupplementation of omega-3 plus Vitamin E on mastalgia in FCC patients, to evaluate its effect with that of Vitamin E only, and to determine the effect of omega-3 plus Vitamin E versus Vitamin E only on the radiological findings in FCC patients. METHODS: This randomized controlled trial was conducted on 120 FCC patients with mastalgia. The participants were randomly assigned into three groups: Omega-3 plus Vitamin E group, Vitamin E only group, and control group. The new breast pain chart was used to assess the severity of mastalgia in the three groups before, through, and after intervention. Radiological assessment was done before and after the intervention. RESULTS: After 3 months of the intervention, there was a statistically significant difference between the three groups regarding radiological results with p > 0.05 and, after the 3rd month of interventions, there was a statistically significant difference between the groups regarding the new pain score with p > 0.001. The median of the new pain score premenstrual was 4.8, 2, and 2.5 in control, omega-3 plus Vitamin E, and Vitamin E only, respectively, but this difference was insignificant between the last two groups (p < 0.996). CONCLUSION: This study showed that Vitamin E and Vitamin E plus omega-3 were effective in relieving mastalgia in FCC patients. However, the addition of omega-3 was ineffective.

scholarly journals Triple-Blinded Randomized Study to Evaluate the Effect of Acetaminophen and Morphine Sulfate on Pain Relief in MI-patients

2021 ◽  
Author(s):  
Mohammad Hossein Bakhshaei ◽  
Shahram Homayounfar ◽  
Behzad Roozbahani ◽  
Melika Malekpour ◽  
Maryam Farhadian
Keyword(s):  
Intervention Group ◽  
Cardiac Performance ◽  
Repeated Measurements ◽  
Morphine Sulfate ◽  
Morphine Sulphate ◽  
Control Group ◽  
Case Group ◽  
Common Symptom ◽  
Significant Difference ◽  
And Control

Background: Myocardial infarction is considered to be the most common symptom of cardiovascular diseases. Regarding the limitation of access to Morphine sulphate as a special drug and complications followed, this study aims to compare the treatment effects of intravenous acetaminophen and morphine sulphate on the reduction of pain in MI patients and to improve the cardiac performance. Methods: The present study is a triple-blind randomized control trial in which 70 patients were divided into two separated groups and the pain was measured using Visual Analogue Scale. All analysis was done using SPSS Software at the significance level of 5 percent. Results: 42 patients were male (60%) of whom 20 were in case group and 22 in control group. There were no significant difference between intervention group and control group in terms of VAS score (p = 0.520). The index change of VAS over the time was statistically significant (p=0.001) in intervention and control groups (intra group change). The results of variance analysis with repeated measurements showed that mean differences of Ejection Fraction over time in both groups of intervention and control was not statistically significant (p=0.28). Conclusion: The findings of this study demonstrate that although Acetaminophen does not have an improved effect on pain control and cardiac performance than Morphine sulphate, it can be still an appropriate alternative for Morphine sulfate due to the lack of destructive effects and its availability.

scholarly journals The Effectiveness of Dialectical Behavior Therapy on Sleep Quality and Pain Management in Multiple Sclerosis

2020 ◽  
Vol 6 (4) ◽  
pp. 205-213
Author(s):  
Marie Abdolghaderi ◽  
◽  
Mohammad Narimani ◽  
Akbar Atadokht ◽  
Abbas Abolghasemi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Pain Management ◽  
Sleep Quality ◽  
Behavior Therapy ◽  
Dialectical Behavior Therapy ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Common Symptom ◽  
Significant Difference ◽  
And Control

Background: Pain can interfere with the daily functioning of patients with Multiple Sclerosis (MS). Furthermore, sleep disturbance is a common symptom of MS. The dialectical behavior therapy program is presented as a detailed structured treatment program that was demonstrated that has effects on the treatment of psychosomatic disorders such as pain and sleep disorders. Objectives: To investigate the effectiveness of dialectical behavior therapy on sleep quality and pain management in patients with MS. Materials & Methods: This research has been carried out as a quasi-experimental with pretest, posttest, and a control group. A total of 24 people were selected through a convenient sampling method from the patients of the MS-Society of Guilan Province, Iran. Then, they are randomly divided into 2 equal groups (experimental and control). The study data were collected through Pittsburgh sleep quality scale and pain self-efficacy questionnaires. The intervention process was performed for the experimental group as 8 training sessions of 90 minutes long. The obtained data were analyzed by univariate analysis of covariance and multivariate analysis of covariance in SPSS v. 24. Results: The results showed a significant difference between the experimental and control groups in terms of pain management (F=4.04) and sleep quality (F=5.64) (P<0.05) and dialectical behavior therapy had a significant statistical effect on sleep quality and pain management. Conclusion: Based on these findings, dialectical behavior therapy can be used to improve the quality of sleep and manage pain in patients with MS.

scholarly journals The Diagnostic Value of Cystatin C and Mild Hypothermia Therapy Based on Immunoturbidimetry Enhanced by Nanospheres in Asphyxia Neonate

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Xiaoping Dang ◽  
Xiaojian Hu ◽  
Yuancui Meng ◽  
Yan’e Yang ◽  
Lingfang Zheng ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Cystatin C ◽  
Renal Damage ◽  
Mild Hypothermia ◽  
Symptomatic Treatment ◽  
Diagnostic Value ◽  
Control Group ◽  
Serum Cystatin C ◽  
Hypothermia Treatment ◽  
Significant Difference

In order to evaluate the early diagnosis value of CysC and the influence of mild hypothermia on the renal damage of asphyxia neonates, the serum cystatin C (CysC) levels of asphyxia neonates and normal neonates were measured by the nanomicrosphere-enhanced immunoturbidimetric method. The treatment was carried out, and the influence of mild hypothermia treatment on the renal damage of asphyxia neonates was analyzed. The results showed that the indicators of the asphyxia group were significantly higher than those of the control group, and the severe asphyxia group was significantly higher than that of the mild asphyxia group, which was statistically significant p < 0.05 ; the heart rate of patients in the mild hypothermia treatment group decreased gradually with the decrease in body temperature. And compared with the control group, there was a significant difference ( p < 0.05 ); after symptomatic treatment, the two groups of ALT, AST, BUN, and SCR were improved to varying degrees, and the difference was statistically significant compared with before treatment ( p < 0.05 ). Studies have shown that serum CysC level can be used as an indicator to detect glomerular filtration function and early asphyxia newborns, and it is sensitive and specific for early diagnosis of kidney damage. At the same time, it can be used to monitor clinical renal function and determine the status of asphyxia newborns.

scholarly journals Effect of Sulfur Mustard Toxicity on FLT3-ITD Gene Mutation in Sulfur Mustard Veterans

2018 ◽  
Vol 12 (4) ◽  
pp. 1-4
Author(s):  
Hossein Ayatollahi ◽  
◽  
Ali Asgharzadeh ◽  
Mohammad Rafiee ◽  
Mohammad Reza Keramati ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Sulfur Mustard ◽  
Lymphoblastic Leukemia ◽  
Control Group ◽  
Control Groups ◽  
Hematopoietic System ◽  
Elapsed Time ◽  
Significant Difference ◽  
Pcr Products ◽  
Healthy Males

Background: Sulfur mustard (SM) is a chemical blistering warfare that affects different organs especially hematopoietic system. Prevalence of acute myeloblastic and lymphoblastic leukemia is increased by sulfur mustard exposure. FLT3-ITD mutation can be effective on leukemogenesis. Therefore, the aim of this study was to verify the frequency of FLT3-ITD mutation in the patients who exposed to SM. Methods: This study was implemented on 42 people poisoned by SM during Iraq-Iran war about three decades ago and is now resident in Mashhad, Iran. The control group included 30 healthy males that are relatives of the patients with first-degree. After DNA extraction, PCR was performed for FLT3-ITD analysis. Results: By analysis of PCR products, no FLT3-ITD mutation was detected in the patient or control groups. There was no significant difference in hematological factors between the two groups. Conclusion: Other mechanisms can lead to leukemia in SM exposed persons. Elapsed time after exposure to sulfur mustard can be effective on leukemogenesis, then future more study may be beneficial for early diagnosis of leukemia in SM exposed veterans.

Physical growth and development characteristics of children with Williams syndrome aged 0–24 months in Zhejiang Province

2019 ◽  
Vol 32 (3) ◽  
pp. 233-237 ◽  
Author(s):  
Dan Yao ◽  
Chai Ji ◽  
Weijun Chen ◽  
Mingyan Li ◽  
Zheng-Yan Zhao
Keyword(s):  
Birth Weight ◽  
Early Diagnosis ◽  
Williams Syndrome ◽  
Growth And Development ◽  
Physical Growth ◽  
Control Group ◽  
Healthy Children ◽  
Department Of Health ◽  
Significant Difference ◽  
Growth Assessment

Abstract Background The objective of this study was to evaluate the physical growth and development characteristics of children with Williams syndrome (WS) aged 0–24 months, and provide help for early diagnosis of WS. Methods A total of 32 cases of children (17 males and 15 females) aged 0–24 months who were diagnosed with WS were enrolled between 2008 and 2017. These children were divided into four different groups: 1–6 months (six cases), 7–12 months (eight cases), 12–18 months (nine cases) and 19–24 months (nine cases). Meanwhile, a total of 32 healthy children (17 males and 15 females) were enrolled in the study from the Department of Health Care for physical examination in our hospital as the control group and matched with each divided group. Weight and height were measured, and meanwhile birth weight and height were also asked and recorded. Results There was no statistically significant difference in birth height between the two groups (p>0.05), and birth weight and the height and weight of the children with WS in the four groups were significantly lower than those of the children in the normal control (NC) group (p>0.05). When the corresponding age of WS children was compared to the Nine City Growth Curve Standards in China, 97% of cases were lagging behind in physical growth and development. Conclusions WS children often have the features of early slow physical growth, which provides certain help for the early diagnosis of WS. Therefore, for younger children, facial features combined with an accurate and objective physical growth assessment and ultrasonic cardiogram can greatly improve the screening rate.

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