scholarly journals Reconstruction of Aesthetic Stomatognathic Function After a High-energy Maxillo-orofacial Fracture: a Case Report

2020 ◽  
Author(s):  
Toshiyuki Kataoka ◽  
Kei Amemiya ◽  
Gen Udagawa ◽  
Yuichi Akagi ◽  
Chie Kagawa ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Maxillofacial Surgery ◽  
High Energy ◽  
Good Prognosis ◽  
Osseointegrated Implants ◽  
Maxillofacial Fractures ◽  
Jaw Fractures ◽  
Treatment Plans ◽  
Oral And Maxillofacial Surgeon ◽  
And Function

Abstract Background: High-energy injury patients with head trauma often present with pan-jaw fractures involving loss of teeth and alveolar bone. They experience a significant decrease in their quality of life due to masticatory disorders, dysarthria, and poor aesthetics. In most cases, they are treated separately by a medical team and a prosthodontist. Moreover, removable dentures provide little satisfaction to the patients.Case presentation: A 29-year-old young woman suffered a high-energy trauma from a fall accident. Following surgery for a jaw fracture, she underwent occlusal reconstruction with osseointegrated implants. The same team performed maxillofacial surgery and prosthetic treatments, and the series of treatment plans included bone grafting and periodontal plastic surgery.Conclusions: The treatment proved successful after more than two years with no signs of peri-implantitis. The patient was highly satisfied with the results. Early intervention by an oral and maxillofacial surgeon in such patients is essential for a good prognosis. Surgeons and prosthodontists who belong to the same team could complete the treatment with fewer surgical procedures. Furthermore, implant treatment in a patient with oral and maxillofacial fractures might improve aesthetics and function.

Tissue engineering in periodontics- A demystifing review

2021 ◽  
pp. 1-5
Author(s):  
Shivani Sachdeva ◽  
Harish Saluja ◽  
Amit Mani ◽  
M.B. Phadnaik
Keyword(s):  
Tissue Engineering ◽  
Tissue Regeneration ◽  
Cell Biology ◽  
Alveolar Bone ◽  
Complete Recovery ◽  
Medical Sciences ◽  
Alternative Approach ◽  
Periodontal Tissue Regeneration ◽  
Novel Concept ◽  
And Function

INTRODUCTION: Novel concept known as tissue engineering is for the betterment of human. The use of much advanced molecular science and cell biology in processing the tissues to regenerate even after the loss of inborn tendency of pluripotent cells to multiply is possible by this new therapy. CONTENT: Periodontal tissue regeneration in both height and function is attributed to a complete recovery of the periodontal structures, that is, the formation of alveolar bone, a new connective attachment through collagen fibers as well as functionally oriented on the newly formed cementum is regeneration. Cell based therapies including tissue regeneration is an alternative approach for the regeneration of tissues damaged by disease or trauma. SUMMARY: Though tissue engineering requires the fundamentals of all the three keys namely genomics, proteomics and biometrics to give the solutions to biological problems appearing in dentistry as well as medical sciences.

scholarly journals A retrospective cohort study of how alveolar ridge preservation affects the need of alveolar ridge augmentation at posterior tooth implant sites

2021 ◽  
Author(s):  
Kai-Fang Hu ◽  
Ying-Chu Lin ◽  
Yu-Ting Huang ◽  
Yu-Hsiang Chou
Keyword(s):  
Treatment Modality ◽  
Alveolar Bone ◽  
Dental Treatment ◽  
Ridge Preservation ◽  
Alveolar Ridge ◽  
Ridge Augmentation ◽  
Posterior Tooth ◽  
Alveolar Ridge Preservation ◽  
Study Results ◽  
Treatment Plans

Abstract Objectives The aim of this study was to assess whether alveolar ridge preservation (ARP) can reduce the need of ridge augmentation at posterior tooth sites. Material and methods This study enrolled patients who received dental implants at posterior tooth sites during 2013–2019. Demographic data and dental treatment histories were collected. Based on healing patterns after tooth extraction, patients were divided into ARP and spontaneous healing (SH) groups. Three surgical treatment plans were devised according to the alveolar bone volume on cone-beam computed tomography (CBCT). The three treatment plans were to perform implant alone, simultaneous guided bone regeneration (GBR) and implantation, and staged GBR before implantation. Statistical analyses were performed to determine relationships. Results There were 92 implant records in the ARP group and 249 implant records in the SH group. A significant intergroup difference was observed regarding the frequency distribution of the treatment modality of staged GBR before implant (χ2 = 15.07, p = 0.0005). Based on the implant alone treatment modality and simple logistic regression, the SH pattern was related to staged GBR before implant (SH vs. ARP: crude odds ratio (OR) = 4.65, 95% confidence interval (CI) = 2.15–11.61, p = 0.0003). After adjusting confounding factors, the risk was still significant (adjusted OR = 5.02, 95% CI = 2.26–12.85, p = 0.0002). Conclusions The study results suggested that ARP is more likely to lead to the treatment modality of implant alone and reduce the need for staged GBR before implantation. Clinical relevance This study describes ARP capable of minimizing the need for staged GBR before implantation and shortening the treatment duration.

Patterns of Pediatric Facial Fractures

2021 ◽  
pp. 194338752199173
Author(s):  
Kevin Hong ◽  
James Jeong ◽  
Yehudah N. Susson ◽  
Shelly Abramowicz
Keyword(s):  
Motor Vehicle ◽  
Maxillofacial Surgery ◽  
Maxillofacial Trauma ◽  
Oral And Maxillofacial Surgery ◽  
Facial Fractures ◽  
Inclusion Criteria ◽  
Motor Vehicle Collisions ◽  
Vehicle Collisions ◽  
Peak Incidence ◽  
Maxillofacial Fractures

Objective: The aim of this study was to assess patterns of maxillofacial trauma in the pediatric population in Atlanta. This information is important to help guide management and allocate resources for treatment of maxillofacial injuries at Children’s Healthcare of Atlanta (CHOA). Methods: This study was a retrospective chart review of children who presented from 2006 to 2015. Inclusion criteria were: (1) age 18 years old or younger, (2) presentation to emergency department, (3) diagnosis of maxillofacial fractures, and (4) evaluation by Oral and Maxillofacial Surgery, Otolaryngology, or Plastic Surgery services. Medical records were reviewed to record demographic, mechanism of injury, fracture location, and yearly incidence of injury. Descriptive statistics were computed to summarize findings and overall trends. Results: During the study period, 39,833 patients were identified. Of them, 1995 met the inclusion criteria. The majority were male (n = 1359, 68%) with an average age of 9.4 years old (range of 1 month to 18 years old). Mechanisms of injury were motor vehicle collisions (MVC) (n = 597, 29.9%), fall (n = 565, 28.3%), sports injury (n = 317, 15.9%), pedestrian struck (n = 215, 10.8%), assault/abuse (n = 204, 10.2%), other (n = 81, 4.1%), or gunshot wound (n = 16, 0.8%). Fracture sites were mandible (n = 519, 26%), complex (n = 479, 24%), nasal (n = 419, 21%), dentoalveolar (n = 279, 14%), orbital (n = 259, 13%), and maxilla (n = 40, 2%). Males had a higher incidence of assault than females (n = 185, 91% of assaults). The incidence of maxillofacial trauma increased with age with a peak incidence in 13 to 16-year-olds (n = 566, 28.3%). During the years examined, there was an upward trend in MVCs as the etiology with a peak incidence of facial fractures due to MVCs occurring in 2015. All other mechanisms remained constant during this time period. Conclusions: There was an increase in pediatric facial fractures secondary to motor vehicle collisions from 2007 to 2015 despite improvements in regulations, traffic safety, and technology.

Outcomes Following Surgical Treatment of Hamate Arthrosis Lunotriquetral Ligament Injuries

Hand ◽  
2021 ◽  
pp. 155894472110432
Author(s):  
Jesse Meaike ◽  
Joshua Meaike ◽  
Sanjeev Kakar
Keyword(s):  
Surgical Treatment ◽  
Treatment Group ◽  
Combined Treatment ◽  
Additional Treatment ◽  
Ligament Injuries ◽  
Interosseous Ligament ◽  
Institutional Review ◽  
Lunotriquetral Ligament ◽  
Treatment Plans ◽  
And Function

Background: An institutional review board–approved study of the functional outcomes of patients after surgical treatment of hamate arthrosis lunotriquetral ligament tear (HALT) lesions was conducted. Methods: In all, 21 wrists in 19 patients underwent arthroscopic, open, or combined treatment of HALT lesions. Seven patients underwent isolated hamate debridement and 14 had concomitant procedures to address lunotriquetral pathology. Nineteen wrists underwent procedures to address additional pathology, including triangular fibrocartilage complex, ulnotriquetral ligament split, and scapholunate ligament injuries. Results: Mayo wrist scores increased from 54 to 71. Sixteen patients had no or mild pain postoperatively, compared with none preoperatively. When stratified by lunotriquetral interosseous ligament management, 75% of the limited treatment group (none or debridement) and 78% of the additional treatment group reported improved pain. Three patients underwent additional surgeries for persistent pain. Conclusion: Resection of the proximal pole of the hamate can improve pain and function for patients with ulnar-sided wrist pain secondary to a HALT lesion. Concomitant wrist pathologies should be considered when determining treatment plans.

Developments and controversies in maxillofacial trauma: Repair of facial injuries

2010 ◽  
Vol 1 (1) ◽  
pp. 20-25 ◽  
Author(s):  
Michael Perry
Keyword(s):  
Functional Disability ◽  
Motor Vehicle ◽  
Sports Injuries ◽  
High Energy ◽  
Aetiological Factor ◽  
Rigid Fixation ◽  
Form And Function ◽  
Improved Outcomes ◽  
The Uk ◽  
And Function

Craniofacial trauma remains a common health problem throughout many areas of the UK. Although the ‘combination of alcohol and testosterone’ is often regarded as a major aetiological factor, a significant number of injuries are not related to either. Motor vehicle collisions and equine-related sports injuries in particular can result in devastating injuries to the skull and face and are frequently seen.Over the last few decades, management has moved away from closed methods to open exposure, anatomical reduction and internal ‘rigid’ fixation of facial fractures, with significant improvements in outcomes. Nevertheless, current management of ‘high energy’ or complex fractures can still result in residual functional disability and cosmetic deformity.Today’s challenge is to restore patients back to their pre-injury form and function, consistently, but this is not always possible. Greater understanding and a number of developments have significantly improved outcomes, although controversy still exists in some areas. Some of these will be discussed.

scholarly journals The Multifarious Functions of Pyruvate Kinase M2 in Oral Cancer Cells

2018 ◽  
Vol 19 (10) ◽  
pp. 2907 ◽  
Author(s):  
Miyako Kurihara-Shimomura ◽  
Tomonori Sasahira ◽  
Chie Nakashima ◽  
Hiroki Kuniyasu ◽  
Hiroyuki Shimomura ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Pyruvate Kinase ◽  
Energy Flow ◽  
Aerobic Glycolysis ◽  
High Energy ◽  
Strongly Correlated ◽  
Mucosal Cells ◽  
Oral Cancer Cells ◽  
And Function

Head and neck cancers, including oral squamous cell carcinoma (OSCC), are the sixth most common malignancies worldwide. OSCC frequently leads to oral dysfunction, which worsens a patient’s quality of life. Moreover, its prognosis remains poor. Unlike normal cells, tumor cells preferentially metabolize glucose by aerobic glycolysis. Pyruvate kinase (PK) catalyzes the final step in glycolysis, and the transition from PKM1 to PKM2 is observed in many cancer cells. However, little is known about PKM expression and function in OSCC. In this study, we investigated the expression of PKM in OSCC specimens and performed a functional analysis of human OSCC cells. We found that the PKM2/PKM1 ratio was higher in OSCC cells than in adjacent normal mucosal cells and in samples obtained from dysplasia patients. Furthermore, PKM2 expression was strongly correlated with OSCC tumor progression on immunohistochemistry. PKM2 expression was higher during cell growth, invasion, and apoptosis in HSC3 cells, which show a high energy flow and whose metabolism depends on aerobic glycolysis and oxidative phosphorylation. PKM2 expression was also associated with the production of reactive oxygen species (ROS) and integration of glutamine into lactate. Our results suggested that PKM2 has a variety of tumor progressive functions in OSCC cells.

scholarly journals Atrophic jaw fracture and predictability in oral rehabilitation: case report

2020 ◽  
Vol 23 (3) ◽  
Author(s):  
João Pedro Miola Siqueira de Oliveira ◽  
Paola Fernanda Cotait de Lucas Corso ◽  
Gilson Cristiano De Oliveira ◽  
Rafaela Scariot ◽  
Davani Latarullo Costa
Keyword(s):  
Case Report ◽  
Dental Implants ◽  
Correct Diagnosis ◽  
Functional Results ◽  
Normal Function ◽  
Oral Rehabilitation ◽  
Osseointegrated Implants ◽  
Fixation Techniques ◽  
Mandibular Body ◽  
Jaw Fractures

Introduction: The treatment of atrophic jaw fractures requires extensive knowledge by the maxillofacial surgeon. The correct diagnosis and planning optimize the possibility of oral rehabilitation towards many possible alternatives. The difficulty in repairing these fractures makes the treatment complex, in which normally invasive techniques are used. However; which give us satisfactory and predictable aesthetic-functional results. Objective: The objective of this work is to report an atrophic jaw fracture and posterior dental implants rehabilitation. Case report: A 53 years old female patient, victim of in face aggression referred to the emergency care. At the clinical examination, the patient had laceration in the upper lip region and the left side of the mandibular area, with bilateral mobility and paresis. In the oral examination, total lower and partial upper edentulism. After tomographic evaluation, a bilateral fracture of the mandibular body was confirmed, with significant bone fragments uneven. Surgery was performed with total transcervical access and use of reconstruction plate. After 90 days of follow-up, the oral rehabilitation with osseointegrated implants was performed. Conclusion: Complex atrophic mandible fractures in total edentulous patients can be treated with open reduction and stable fixation, allowing a faster return to normal function, improve of quality of life and assists in increasing safety for implant installation.KeywordsEdentulous jaw; Jaw fixation techniques; Dental implants.

scholarly journals Detachable Lip and Cheek Plumper for Rehabilitation of Facial Disfigurement

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Nada Fathalla Abdelbagi ◽  
Ibrahim Ahmed Ismail ◽  
Fadia Awadalkreem ◽  
Mohammed Nasser Alhajj
Keyword(s):  
Social Life ◽  
Alveolar Bone ◽  
Treatment Plan ◽  
Young Male ◽  
Cost Effective ◽  
Surgical Removal ◽  
Individual Character ◽  
Swallowing Difficulties ◽  
Oroantral Communication ◽  
And Function

Background. Hemimaxillectomy of acquired palatal defects may predispose the patient to hypernasal speech, leakage of fluids into the nasal cavity, impaired masticatory function, and swallowing difficulties leading to a detrimental impact on the quality of life. Sequentially, it can also affect individual character and trust in social life, leading to social phobia and anxiety. This article presents prosthodontic management of a young male patient with deformation of the entire right half of the face due to surgical removal of odontogenic myxoma. It describes a method where the clinician utilized a simple, noninvasive, and cost-effective technique to cut the weight of the obturator and to attain aesthetics, utilizing a detachable lip and cheek plumper. Case Presentation. A 19-year-old male attended the Prosthodontic Clinics at Faculty of Dentistry, the University of Khartoum, eight months after the surgical removal of a tumor. The chief complaint was difficulty eating or drinking. Furthermore, he dropped out of school because of his facial deformity and his indistinct voice. Medical and dental history revealed surgical resection of the entire right half of the maxillary alveolar bone due to myxoma. Intraoral examination revealed a well-healed surgical defect in the maxillary right buccal vestibule creating an oroantral communication. A treatment plan was formulated, keeping the patient’s demand in mind. The decision was made to treat the patient with a maxillary obturator that would gain its support from the remaining teeth and tissues with a detachable cheek and lip plumper. The use of dental magnets as a means of attachment was elected. Conclusion. This article has described a simple, noninvasive, and cost-effective method to improve facial appearance in patients with hollow faces. The plumper prosthesis successfully improved the patient’s appearance to the extent that comfort and function would permit and encourage self-esteem.

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