Clinicopathological analysis of 55 cases of ossifying fibroma of the jaw

Abstract Objective : The purpose of this study was to investigate 55 cases of ossifying fibroma to analyze their clinical and pathological data. Methods : The clinical data, age, imaging performance, serology and their prognosis of 55 cases were analyzed and also Chi-square Test for statistical analysis were made. Results : The COF took up 70.9%, JPOF took up 20.0%, and JTOF took up 5.5%. 62.5% COF were the females, 75% JPOF concentrated in females, 66.7% JTOF concentrated in males. 66.7% COF located in the mandible. 54.5% JPOF were in the maxilla, in which 4 cases (4/11,36.4%) involved the para-nasal sinus. JTOF mainly concentrated in the mandible (66.7%). 2 cases (3.6%) exhibited multi-lesions. 7 cases (12.7%) were found the level of serum ALP up-regulated, and the up-regulation concentrated in younger patients (0~29 years) ( P <0.05). In radiographic presenting, only 7.3% displayed unclear borderline, and 87.3% exhibited mixed lesions, 7.3% was X-ray transparent, 5.5% was X-ray opaque. 29.1% had thinning bone cortex and 1 cases was found the bone cortex destructed (1/55,1.8%).18.2% OF appeared tooth displacement, and 9.1% displayed the amputated-like absorption of tooth root. 32 cases were followed up, 31.3% underwent conservative treatment suffered relapse, there was significant differences between the conservative and radical treatment ( P <0.05). Conclusions: The main subtype of OF was COF, JPOF and JTOF were relatively less. The majority of sporadic OF was single lesion, multi-lesions were rare. COF occurred with the female predilection in mandible, while JPOF occurred with the female predilection in maxilla; JTOF was the youngest, most occurred in adolescent males in mandible. Tooth displacement was often seen, and the root appeared as an amputated-like resorption. Younger patients were more likely to have elevated ALP. The patients underwent conservative curettage had relatively higher rate of relapse, the lesion should be resected radically to prevent relapse. Keywords: ossifying fibroma, clinical, pathological, jaw

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Hubungan antara Luas Lesi pada Foto Toraks Penderita TB Paru Dewasa yang Memiliki Riwayat Diabetes Melitus dengan Indeks Massa Tubuh di Rumah Sakit Hasan Sadikin Bandung

Jurnal Radiologi Indonesia ◽

10.33748/jradidn.v1i3.18 ◽

2016 ◽

Vol 1 (3) ◽

pp. 138-144

Author(s):

Ina Edwina ◽

Rista D Soetikno ◽

Irma H Hikmat

Keyword(s):

Chest Radiograph ◽

Chi Square ◽

Pulmonary Tb ◽

X Ray ◽

Consecutive Sampling ◽

Close Relationship ◽

Chi Square Test ◽

Chest X Ray ◽

The Relationship ◽

Diabetes Melitus

Background: Tuberculosis (TB) and diabetes mellitus (DM) prevalence rates are increasing rapidly, especially in developing countries like Indonesia. There is a relationship between TB and DM that are very prominent, which is the prevalence of pulmonary TB with DM increased by 20 times compared with pulmonary TB without diabetes. Chest X-ray picture of TB patients with DM is atypical lesion. However, there are contradictories of pulmonary TB lesion on chest radiograph of DM patients. Nutritional status has a close relationship with the morbidity of DM, as well as TB.Objectives: The purpose of this study was to determine the relationship between the lesions of TB on the chest radiograph of patients who su?er from DM with their Body Mass Index (BMI) in Hasan Sadikin Hospital Bandung.Material and Methods: The study was conducted in Department of Radiology RSHS Bandung between October 2014 - February 2015. We did a consecutive sampling of chest radiograph and IMT of DM patients with clinical diagnosis of TB, then the data was analysed by Chi Square test to determine the relationship between degree of lesions on chest radiograph of pulmonary TB on patients who have DM with their BMI.Results: The results showed that adult patients with active pulmonary TB with DM mostly in the range of age 51-70 years old, equal to 62.22%, with the highest gender in men, equal to 60%. Chest radiograph of TB in patients with DM are mostly seen in people who are obese, which is 40% and the vast majority of lesions are minimal lesions that is equal to 40%.Conclusions: There is a signifcant association between pulmonary TB lesion degree with BMI, with p = 0.03

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The prevalence of olfactory dysfunction and its associated factors in patients with COVID-19 infection

10.1101/2021.01.27.21250153 ◽

2021 ◽

Author(s):

Md Mehedi Hasan ◽

Naima Ahmed Tamanna ◽

Mohammad Nasimul Jamal ◽

Md Jamal Uddin

Keyword(s):

Associated Factors ◽

Smoking Status ◽

Age Groups ◽

Olfactory Dysfunction ◽

Test Results ◽

Chi Square ◽

Younger Patients ◽

Regular Screening ◽

Chi Square Test ◽

Observational Cohort

AbstractObjectiveTo determine the prevalence of olfactory dysfunctions, mainly, anosmia and to identify its associated factors in patients with COVID-19 infection.Study designA hospital-based prospective observational cohort studySettingA COVID dedicated hospital, Square Hospitals Ltd., Dhaka, Bangladesh.MethodsWe collected patients’ information including laboratory-confirmed COVID-19 test results. We used Pearson Chi-square test and logistic regression model to assess the associations between demographic and clinical characteristics and olfactory outcomes.ResultsOut of 600 COVID-19 positive patients, 38.7% were diagnosed with olfactory dysfunction. Our analyses showed that patients’ age, smoking status, cough, dyspnea, sore throat, asthenia, and nausea or vomiting were significantly associated with the anosmia. We observed the risk of developing anosmia was greater in younger patients than in older patients, and this risk decreased as age increased [odds ratio (OR) range for different age groups: 1.26 to 1.08]. Smoking patients were 1.73 times more likely to experience anosmia than non-smoking patients [OR=1.73, 95% confidence interval (CI) = 1.01-2.98]. In addition, patients complained asthenia had a significantly double risk of developing the anosmia [OR = 1.96, CI = 1.23-3.06].ConclusionsOur study shows that about 39% of patients diagnosed with olfactory dysfunction. Patients’ age, smoking status, and asthenia are significantly positively associated with the anosmia. Since anosmia can be a significant marker for the diagnosis of COVID-19, we suggest regular screening of olfactory dysfunction in patients with early symptoms of COVID-19, particularly younger patients, smoker, and complained asthenia.

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184 EFFECTS OF X-RAY ELECTROMAGNETIC RADIATION ON BOVINE OOCYTE DEVELOPMENT

Reproduction Fertility and Development ◽

10.1071/rdv22n1ab184 ◽

2010 ◽

Vol 22 (1) ◽

pp. 250

Author(s):

W. E. Snyder ◽

J. T. Aaltonen ◽

H. D. Sigal ◽

N. M. Loskutoff

Keyword(s):

Electromagnetic Radiation ◽

High Energy ◽

X Rays ◽

Embryo Production ◽

Chi Square ◽

X Ray ◽

Chi Square Test ◽

Bovine Oocytes ◽

Experimental Group

This study examined the effects of X-rays on bovine oocytes used for in vitro embryo production. In recent years, airport security has become more stringent and the use of X-ray screening may be required for all items, which could be problematic when transporting oocytes. Ionizing radiation such as X-rays are high-energy particles that can penetrate into the nucleus of a cell and cause single and double-strand breaks in the DNA chain. Oocytes exposed to X-ray radiation may have DNA damage affecting maturation, fertilization, and embryonic development. Bovine ovaries obtained from a local abattoir were used to collect immature oocytes by follicular aspiration. The oocytes were divided into a control group and an experimental group then placed in maturation medium. The oocytes in the experimental group were placed in a hospital X-ray machine with a single exposure of 100 mA, 120 kVp for 0.3 s. This exposure challenged the oocytes with a comparable, calculated amount of mrems equivalent to a single screening from an airport X-ray machine (30 mrems). After X-ray exposure, the experimental group was cultured with the control at 37°C and 5% CO2. After 18 h, cryopreserved bovine sperm were thawed and processed using BoviPure (Nidacon International, Mölndal, Sweden) density gradient centrifugation and the oocytes were inseminated with 1 × 106 sperm in fertilization medium at 37°C and 5% CO2. After 24 h, both groups were transferred to 50-μL droplets of G1 medium (Vitrolife, Göteborg, Sweden) at 37°C and 6% CO2 and both were transferred into G2 medium after 72 h. Development of the oocytes was scored after an additional 72 h. Results were based on 2 criteria: the percent cleaved (presumptive fertilization) and the percent cleaved that developed to morula and blastocyst stages. The results indicated no significant difference in the percentages of oocytes cleaving after insemination for the control and experimental groups (P = 0.403, chi-square test). However, there was a significant increase (P = 0.037, chi-square test) in the percentages of morulae and blastocysts developing in the control (non-irradiated) v. experimental (X-rayed) groups. The outcome of this study cautions on the potential damage caused to bovine oocytes used for embryo production in vitro when exposed to X-ray electromagnetic radiation during routine air transport screening operations. Table 1.

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A Comparison Of Acute Myelogenous Leukemia Induction Therapies: High Dose Daunorubicin Vs Idarubicin

Blood ◽

10.1182/blood.v122.21.3951.3951 ◽

2013 ◽

Vol 122 (21) ◽

pp. 3951-3951

Author(s):

Viet Q. Ho ◽

Robert Cade ◽

Gene A. Wetzstein ◽

Van D Hoang ◽

Alan List ◽

...

Keyword(s):

Overall Survival ◽

Stem Cell ◽

Induction Chemotherapy ◽

Cox Regression ◽

Myelogenous Leukemia ◽

High Dose ◽

Consolidation Chemotherapy ◽

Chi Square ◽

Younger Patients ◽

Chi Square Test

Abstract Background The optimal induction regimen for patients with acute myeloid leukemia (AML) remains unclear. Intensification of daunorubicin (DNR) dose during induction chemotherapy (90 mg/m2) in younger patients with AML has yielded improved complete remission (CR) rates and overall survival (OS) compared to 45 mg/m2. To date, daunorubicin 90 mg/m2 has not been compared to idarubicin for induction in younger patients. Herein, we compare induction outcomes using cytarabine plus either IDA or DNR 90 mg/m2 as induction chemotherapy in patients less than 65 years of age. Methods This is a single institution case controlled retrospective study evaluating patients aged 18 to 65 years who received induction chemotherapy for AML with either cytarabine 100 mg/m2 x 7 days and DNR 90 mg/m2 x 3 days or cytarabine 200 mg/m2 x 7 days and IDA 12 mg/m2 x 3 days at Moffitt Cancer Center (MCC). Patients who achieved CR were offered consolidation chemotherapy and/or allogeneic transplant as per standard guidelines. Clinical endpoints that were measured and compared include CR, OS and leukemia free survival (LFS). Patients were censored at time of transplant. Categorical variables were compared using Chi square test, and t- test for continuous variables. Cox regression was used for multivariate analysis. Remission rate were compared using Chi square test. Kaplan-Meier estimates were used for OS and LFS and Log Rank test was used to compare groups. All analyses were conducted using SPSS version 21. Results Between January 2005 and April 2013, 175 patients<= 65 years with newly diagnosed AML were included; 84 patients received induction chemotherapy at MCC with high dose DNR and 91 patients received IDA as described above. Baseline characteristics were similar between the two groups (Table 1). The median duration of follow up was 25.9 months. CR rates were similar between the DNR and IDA (74% vs 76%, p = 0.95). Rates of CR after first induction were also similar (61% vs 62%, p = 0.33). The median LFS was 10.2 months with DNR compared to 6.4 months with IDA (p=0.476) (Figure 1). Median OS was not reached in the DNR arm compared to the 18.4 months in the IDA arm (p=0.107) (Figure 2). No significant differences were observed in the number of patients receiving consolidation chemotherapy (70% vs 66%, p = 0.54) or allogeneic stem cell transplant (23% vs 25%, p = 0.68). There was no difference in 60 day mortality during induction chemotherapy (4.8% vs 5.5%, p = 1.00). In multivariate cox regression analysis anthracycline selection did not affect OS after adjusting for cytogenetic and molecular profile, CR, consolidation received or stem cell transplantation (hazard ratio, 1.25; 95% CI, 0.74-2.09; p = 0.402). Conclusion In younger adults with AML, induction chemotherapy with either IDA or DNR yielded similar rates of CR and LFS and OS. However, a trend towards increased overall survival was observed in the DNR cohort, adding further support to the use of high-dose daunorubicin as standard induction for AML. Disclosures: No relevant conflicts of interest to declare.

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The prediction of impacted versus spontaneously erupted mandibular third molars

Progress in Orthodontics ◽

10.1186/s40510-021-00376-2 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Amanda Silva De Sousa ◽

José Valladares - Neto ◽

David Normando

Keyword(s):

Kappa Statistics ◽

X Rays ◽

Third Molars ◽

Accuracy Rate ◽

Predictive Capacity ◽

Chi Square ◽

X Ray ◽

Prognostic Accuracy ◽

Chi Square Test ◽

Mandibular Third Molars

Abstract Background To evaluate the predictive capacity of orthodontists and oral maxillofacial surgeons (OMFSs) in anticipating the process of impaction or eruption of lower third molars (L3Ms) through the examination of serial panoramic radiographs. Methods Sixty-eight lower third molars (L3Ms) were analyzed in 34 orthodontically treated patients without extraction. Twenty-seven OMFSs and 27 orthodontists were randomized in order to analyze the radiographs. Initially, the evaluators issued the prognosis for the L3Ms in XR1, a posterior for the XR1 + XR2. Concordance of the diagnosis was examined using Kappa statistics, and the differences between the groups of evaluators were examined using the chi-square test at p<0.05. Results When examining XR1 in cases where the teeth erupted spontaneously, the prognostic accuracy rate for OMFSs and orthodontists was similar, 63 and 65.7%, respectively (p=0.19). When evaluating XR1 + XR2, the accuracy among orthodontists (60%) was similar to that reported for XR1 (p=0.19), while OMFSs presented a reduction in the accuracy (55.3%, p<0.0001). When the L3Ms remained impacted, accuracy in XR1 was lower than in spontaneously erupting L3Ms, although similar between OMFSs (50.1%) and orthodontists (49.1%). Furthermore, for impacted L3Ms, when examining XR1 + XR2, the OMFSs presented a significant higher accuracy (71.8%, p <0.0001). Conclusions Orthodontists and OMFSs seem unable to predict spontaneous eruption or impaction of the lower third molars from single or longitudinal x-rays. When adding a second longitudinal x-ray, orthodontists and more significantly OMFSs tend to indicate more extractions.

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Assessment of breast arteries and lymph nodes by 3D MR angiography enhancement imaging: feasibility and pilot clinical results

BMC Medical Imaging ◽

10.1186/s12880-021-00629-w ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yang Liu ◽

Jiaxin Hou ◽

Zhijun Zhu ◽

Bingguang Liu ◽

Manrui Cao ◽

...

Keyword(s):

Lymph Nodes ◽

Clinical Results ◽

Average Score ◽

Imaging Method ◽

Chi Square ◽

Lateral Thoracic Artery ◽

Good Imaging ◽

Chi Square Test ◽

The Difference ◽

Imaging Performance

Abstract Background Conventional dynamic contrast enhanced (DCE) magnetic resonance (MR) hardly achieves a good imaging performance of arteries and lymph nodes in the breast area. Therefore, a new imaging method is needed for the assessment of breast arteries and lymph nodes. Methods We performed prospective research. The research included 52 patients aged from 25 to 64 between June 2019 and April 2020. The isotropic e-THRIVE sequence scanned in the coronal direction after DCE-THRIVE. Reconstructed images obtained by DCE-THRIVE and the coronal e-THRIVE were compared mainly in terms of the completeness of the lateral thoracic artery, thoracodorsal artery, and lymph nodes. We proposed a criterion for evaluating image quality. According to the criterion, images were assigned a score from 1 to 5 according to the grade from low to high. Two board-certified doctors evaluated images individually, and their average score was taken as the final result. The chi-square test was used to assess the difference. Results The coronal e-THRIVE score is 4.60, which is higher than the DCE-THRIVE score of 3.48, there are significant differences between the images obtained by two sequences (P = 1.2712e−8). According to the score of images, 44 patients (84.61%) had high-quality images on the bilateral breast. Only 3 patients’ (5.77%) images were not ideal on both sides. The improved method is effective for most patients to get better images. Conclusions The proposed coronal e-THRIVE scan can get higher quality reconstruction images than the conventional method to visualize the course of arteries and the distribution of lymph nodes in most patients, which will be helpful for the clinical follow-up treatment.

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A comparative evaluation of clinical features of a restorative material packed in blisters

Nowa Stomatologia ◽

10.25121/ns.2018.23.4.148 ◽

2018 ◽

Vol 23 (4) ◽

Author(s):

Alicja Porenczuk ◽

Bartłomiej Górski ◽

Wioletta Bielas ◽

Dariusz Gozdowski ◽

Agnieszka Mielczarek

Keyword(s):

Clinical Features ◽

Clinical Work ◽

Cross Infection ◽

The Other ◽

Survey Study ◽

Restorative Material ◽

Chi Square ◽

Chi Square Test ◽

Single Lesion ◽

Indications For Use

Introduction. Vast indications for use of the polymer resins in cavity reconstruction result from a progress in manufacturing process. A new group of cross-infection control restoratives provide sterility of the treatment together with fulfillment of both the patients and the dentists requirements. A disposable packaging enables usage of the material’s portion to restore a single lesion and prevents its further re-use. Aim. The aim of the study was to compare clinical features, such as application, modelling, polishing and esthetics, of a restorative material packed in blisters to other polymer restorative materials. Material and methods. A survey study was conducted among 56 students of dentistry. They were given a blister of the material and asked to use it for restoration of a chosen cavity. Afterwards, they were asked to fill in a questionnaire concerning the clinical work with the material. All returned data was analyzed with chi-square test at p < 0.05. Results. The overall responsive rate was 44.6%. Taking the material from the blister was comfortable for 84%. The material’s application in the cavity was estimated well by 92% of the respondents. 72% believed its application and polishing was significantly easier than the other materials. 72% of the students claimed the material was more esthetic than the other restoratives. Conclusions. The restorative material packed in blisters is comfortable to apply in the cavity, can be easily modelled and polished. Blisters are comfortable to use by the dentist and the assistant. Due to high esthetics, it is dedicated for esthetic restorations.

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Cervical spondylosis: a common finding in vertigo patients

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20185055 ◽

2018 ◽

Vol 5 (1) ◽

pp. 33

Author(s):

Santosh Uttarkar Pandurangarao ◽

Shraddha Subhash Bhoyar ◽

Aravind Darga Ramchandra ◽

Sridurga Janarthanan

Keyword(s):

Cervical Spine ◽

Cervical Spondylosis ◽

Lateral View ◽

Common Finding ◽

Common Symptom ◽

Chi Square ◽

X Ray ◽

Common Causes ◽

Chi Square Test ◽

Male Patients

Background: Vertigo or giddiness is a common symptom seen in patients attending ENT OPD. Vestibular and neurological pathologies being the known common causes. Cervical spondylosis is being established as a common condition leading to vertigo. Our aim is to evaluate the significance of cervical spondylosis as a cause in patients with vertigo.Methods: Hundred patients of either sex, between the age group of 23-64 years, with vertigo were evaluated with complete history and clinical examination followed by PTA and impedance audiometry. All common causes of vertigo were ruled out and these patients were screened with digital x-ray cervical spine in lateral view to rule out cervical spondylosis. The results were analysed statistically using Chi square test and inference was drawn. Results: Out of 100 (100%) patients evaluated, 58 (58%) were female patients and 42 (42%) male patients. Cervical spondylosis was found to be present in 47 (47%) patients.Conclusions: Cervical spondylosis was found as a common finding in patients with vertigo. It can be ruled out easily using a simple investigation of cervical spine x-ray, in patients where other commoner causes cannot be established.

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Prevalence of pneumonia by chest x-ray, associated demographic characteristics and health risk factors among COVID-19 patients in Ghana

Ghana Medical Journal ◽

10.4314/gmj.v55i2s.4 ◽

2021 ◽

Vol 55 (2) ◽

pp. 21-28

Author(s):

Joseph A. Oliver-Commey ◽

Peter Puplampu ◽

Christian Owoo ◽

Kwame Asare-Boateng ◽

Anita O. Yawson ◽

...

Keyword(s):

Data Extraction ◽

Personal Characteristics ◽

International Travel ◽

Contact Tracing ◽

P Value ◽

Chi Square ◽

X Ray ◽

Discharge Plan ◽

Chi Square Test ◽

Chest X Ray

Objective: The study was conducted to determine the prevalence of radiologically diagnosed pneumonia among COVID-19 patients and associated factors.Design, setting, and participants: A retrospective manual data extraction of 275 medical records of COVID-19 patients was conducted at two COVID-19 national treatment centres in Accra from March to May 2020. All patients had a chest x-ray done.Main outcome and analysis: The main outcome was the presence of pneumonia. Descriptive statistics and Chi-square test of independence were employed to determine the associations between independent variables and the presence of pneumonia. All analysis was performed using Stata 16, and a p-value ≤ 0.05 was deemed significantResults: The prevalence of pneumonia was 44%(95%CI) =38.2-50.0). Chi-square independent test indicated that pneumonia in the COVID-19 patients was associated with educational level, history of domestic and international travel, mass gathering in the past 14 days before diagnosis, and discharge plan (p-value< 0.05). Patients classified as secondary cases (61.5%) and those discharged as fully recovered from the health facility (61.2%) had a higher prevalence of pneumonia. In addition, COVID-19 patients with hypertension (32.1%) and asthma (5.2%) had a significantly higher prevalence of pneumonia.Conclusion: Overall, the prevalence of pneumonia was 44% and was associated with the demographic and personal characteristics of the patients. Early detection through contact tracing and community surveillance should be intensified to pick up more asymptomatic cases. The role of the chest x-ray for triaging patients and for clinical management of symptomatic patients remains key.

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COVID-19 Pandemic-Adapted Radiotherapy Guidelines: Are They Really Followed?

Current Oncology ◽

10.3390/curroncol28050288 ◽

2021 ◽

Vol 28 (5) ◽

pp. 3323-3330

Author(s):

Elena Galofaro ◽

Claudio Malizia ◽

Ilario Ammendolia ◽

Andrea Galuppi ◽

Alessandra Guido ◽

...

Keyword(s):

Hospital Environment ◽

Data Collection Form ◽

Chi Square ◽

Age And Gender ◽

Younger Patients ◽

High Compliance ◽

Lower Treatment ◽

Chi Square Test ◽

And Gender ◽

Collection Form

Background: In our department, we provided guidelines to the radiation oncologists (ROs) regarding the omission, delay, or shortening of radiotherapy (RT). The purpose was to reduce the patients’ exposure to the hospital environment and to minimize the departmental overcrowding. The aim was to evaluate the ROs’ compliance to these guidelines. Methods: ROs were asked to fill out a data collection form during patients’ first visits in May and June 2020. The collected data included the ROs’ age and gender, patient age and residence, RT purpose, treated tumor, the dose and fractionation that would have been prescribed, and RT changes. The chi-square test and binomial logistic regression were used to analyze the correlation between the treatment prescription and the collected parameters. Results: One hundred and twenty-six out of 205 prescribed treatments were included in this analysis. Treatment was modified in 61.1% of cases. More specifically, the treatment was omitted, delayed, or shortened in 7.9, 15.9, and 37.3% of patients, respectively. The number of delivered fractions was reduced by 27.9%. A statistically significant correlation (p = 0.028) between younger patients’ age and lower treatment modifications rate was recorded. Conclusion: Our analysis showed a reasonably high compliance of ROs to the pandemic-adapted guidelines. The adopted strategy was effective in reducing the number of admissions to our department.

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