scholarly journals Short and mid-term results of thoracoscopic surgery for esophageal atresia in low birth weight infants:A single-center clinical experience

Author(s):  
Lei Yan ◽  
MingKun Liu ◽  
Bing Zhang ◽  
Yu Lin ◽  
Dianming Wu ◽  
...  

Abstract Purpose: To evaluate the short-term safety and long-term efficacy of thoracoscopic surgery for esophageal atresia(EA) in low birth weight infants. Methods: From January 2011 to December 2019,a retrospective analysis on clinical data of 48 cases of low birth weight infants of EA. The clinical data were divided according to surgical methods: Thoracoscopy group A and thoracotomy group B. Variables of intra-operation, postoperative complications and mid-term postoperative complications were compared between the two groups.Results: 3 were discharged due to treatment abandoning. there were 17 cases in thoracoscopy group A and 28 cases in thoracotomy group B. The operation time of group A(172.41±20.00min)was longer than B(149.82±13.91min),the difference was statistically significant (P<0.05).the intraoperative blood loss of group A(7.41±2.83ml) was less than B(18.61±3.60ml),the difference was statistically significant (P<0.05).postoperative mechanical ventilation time, thoracic drainage time, hospital stay were not significantly different between the two groups. the incidence of anastomotic stenosis in group B(58.82%) was higher than in A(28.57%),the difference was statistically significant (P=0.045).There was no significant difference in the incidence of esophageal anastomotic fistula and recurrent tracheoesophageal fistula. After 3 years of follow-up, the incidence of thoracic deformity in group B(25%) was higher than in A(0%).The difference was significant(P=0.034).However, no significant difference was observed among the gastroesophageal reflux, symptomatic stenosis, tracheomalacia. Conclusion: Compared with thoracotomy, thoracoscopy in low weight infants with EA has the advantages of smaller incision, fewer intraoperative bleeding, and less incidence of thoracic deformities. Thoracoscopy might be a feasible surgical option for low weight infants when performed by a surgeon who has rich experience. The major mid-term complications after surgery are esophageal stenosis, gastroesophageal reflux and tracheomalacia.

2021 ◽  
Vol 4 (35) ◽  
pp. 357-363
Author(s):  
Daniela Alencar Moreira ◽  
Neyla Edelwais Silva ◽  
Cervantes Caporossi

Introduction: Monitoring of parenteral nutrition therapy (NPT) in critical neonates is essential for clinical outcome, and it is indispensable to quantify the infused NPT compared to the prescribed and prepared amount. The purpose of this study is to account for monetary losses due to unmanaged NPT disposal. Methods: Neonates were stratified into two groups. Group A (n = 6): low birth weight preterm infants; Group B (n = 6): preterm infants of very low weight and extreme low weight <1,000 g, followed by 167 days of NPT, compared to the percentage differences in volumes, calories and average monetary losses of the despised volumes. Results: The percentage difference between volume prescribed and prepared for group A was 42.49 ± 18.27% and for group B it was 86.82 ± 63.52% (p = 0.003). Between volume prepared and infused, the difference was 63.15 ± 15.11% for group A and 47.98 ± 17.25% for group B (p = 0.003). Among prescribed and infused calories, the difference was 22.61 ± 8.69% for group A and 13.92 ± 3.45% for group B (p = 0.04). The average monetary losses of the despised volumes were R$ 992.68 and R$ 1,296.81 (p = 0.0129), respectively. Conclusion: Infused NPT was lower than prescribed, resulting in lower caloric intake for neonates and significant financial losses associated with NPT disposal.


1970 ◽  
Vol 10 (3) ◽  
pp. 177-180
Author(s):  
B Mahamuda ◽  
S Tanira ◽  
W Feroza ◽  
HA Perven ◽  
A Shamim

Context: Anaemia is a common pregnancy related disorder in Bangladesh that causes various maternal and fetal problems. A prospective study was designed to see the associated maternal factors and fetal outcome in different categories of anaemia and to compare with that of normal pregnancy. Methods: The study was carried out on 60 Bangladeshi women within 35-40 weeks of gestation. Among them, 20 with normal uncomplicated pregnancies were considered as control group or group A, another 27 having pregnancies with mild anaemia were considered as group B, and 13 having pregnancies with moderate anaemia were considered as group C. Severe anaemic mothers were considered as group D, but not found during the period of collection of data for this study. The mothers were selected as who were suffering from antenatal anaemia i.e. having heamoglobin level <10 gm/dl (mild, if <10 gm/dl; moderate, if <8 gm/dl; and severe, if <6 gm/dl) and control i.e. having heamoglobin level ≥10 gm/dl. The foetal outcome was observed and recorded after delivery. Results: The mean age of the mother was 23.65±3.83 years, 27.26±4.93 years and 25.85±4.62 years and the mean number of gravidity was 1.65±0.67, 2.15±0.72 and 2.69±1.03 in group A, group B and group C respectively. The difference was statistically highly significant in between A and C (p<0.001) and also significant in between A & B and B & C (p<0.05). The mean gestational age of the mother was 38.65±0.88 weeks, 37.37±1.01 weeks and 37.15±1.28 weeks in group A, group B and group C respectively and the difference was statistically significant between A & B and A & C (p<0.001). The mean birth weight of the neonate was 3.09±0.30 Kg., 2.99±0.16 Kg. and 2.95±0.21 Kg., while the mean APGAR score of the neonate at first minute of birth was 8.90±1.07, 8.11±0.89 and 7.69±0.48 in group A, group B and group C respectively. No significant difference was found in birth weight of the newborn babies in between the groups of the mothers. However, the difference was found significant in between A & B (p<0.01) and A & C (p<0.001), in case of APGAR score. Key words: Maternal anaemia, gestational age, neonatal outcome, birth weight, APGAR score. DOI: http://dx.doi.org/10.3329/bjms.v10i3.8361 BJMS 2011; 10(3): 177-180


2021 ◽  
pp. 112067212110233
Author(s):  
Marcelina Sobczak ◽  
Magdalena Asejczyk ◽  
Malwina Geniusz

Objectives: The main goal of this research was to determine the differences between the values of intraocular pressure (IOP) in the supine and sitting positions, and to assess the effect of age and cardiovascular parameters. Methods: Seventy-two healthy adults were enrolled and classified into age groups: 20–30 years (group A), 31–40 years (group B), and 41–71 years (group C). Corneal biometry and cardiovascular parameters, such as heart rate (HR), were measured. IOP measurements were taken in the sitting position (IOPS) and in the supine position (IOPL) using the iCare® Pro tonometer. Results: A significant difference between the IOPS and IOPL in the entire cohort was found ( p < 0.001). Regarding the age subgroups, a significant difference ( p < 0.001) between the IOPS and IOPL was obtained in group A (2.6 ± 1.6 mmHg) and group C (1.5 ± 1.3 mmHg). There were no significant differences in the IOPS between groups. The highest IOP values were obtained for group A. The correlations between HR and IOPS are statistically significant for group A and group B, and for HR and IOPL-S for group B only. Multivariate analysis showed that HR has a significant influence on the difference in IOP in the two body positions. Conclusion: A statistically significant difference between the effect of age and the values of IOPS and IOPL was shown. Cardiovascular parameters showed some relevant statistical dependencies, but with a rather marginal significance in young people. The influence of body position for the measurement of IOP for healthy subjects does not seem to matter, despite the fact that there are some dependencies that are statistically significant.


2011 ◽  
Vol 14 (3) ◽  
pp. 193-198 ◽  
Author(s):  
Qori’Ila Saidah ◽  
Yeni Rustina ◽  
Nani Nurhaeni

AbstrakKondisi klinis dan perawatan di ruang rawat intensif pada Bayi Berat Lahir Rendah (BBLR) mempengaruhi status banguntidurnyadan menyebabkan kecemasan pada ibu. Tujuan penelitian ini mengidentifikasi pengaruh perawatan metode kanguruterhadap kecemasan ibu dan status bangun-tidur BBLR. Rancangan penelitian one group pretest posttest design dengan sampel16 ibu dan BBLR di sebuah rumah sakit Surabaya secara consecutive sampling. Kecemasan ibu diukur dengan PSS: NICU danstatus bangun tidur dengan modifikasi skala Brazelton oleh Priya. Hasil analisis uji statistik menggunakan Wilcoxon Sign RankTest dan uji Friedman menunjukkan ada perbedaan bermakna (p= 0,000; α= 0,05). PMK mempunyai pengaruh signifikanterhadap perubahan kecemasan ibu dan status bangun-tidur BBLR. Tenaga kesehatan disarankan mengembangkan PMK untukpeningkatan status kesehatan ibu, juga tumbuh kembang bayi yang optimal.Kata kunci: kecemasan ibu, perawatan metode kangguru, status bangun-tidur BBLR.AbstractClinical condition and treatment at Low Birth Weight Infants (LBW) in the intensive care unit affects sleep-wake status andcauses anxiety for the mother. The aims of this study is to identify the influence of methods of kangaroo care on maternalanxiety and sleep-wake status of LBW. The design of this study was one group pretest posttest design with sample of 16 mothersand low birth weight in a hospital in Surabaya by consecutive sampling. Maternal anxiety was measured with the PSS: NICUand sleep-wake status with Brazelton scale modified by Priya. The result of statistical analysis test using Wilcoxon Sign RankTest and Friedman test showed there are significant difference (p= 0.000; α= 0.05). KMC has a significant influence onchanges in maternal anxiety and sleep-wake status of LBW. Health care provider are recommended to develop KMC forimprovement of maternal health status, as well as the optimal infant growth and development.Keywords: maternal anxiety, kangaroo mother care, sleep-wake state in low birth weight baby


Jurnal NERS ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 111
Author(s):  
Desriati Devi ◽  
Yeni Rustina ◽  
Defi Efendi

Introduction: Low birth weight (LBW) infants who have been hospitalized are exposed to various conditions that provoke discomfort, which could trigger a stress response and growth disorders. This study aimed to identify the effects of auditory stimuli from Murottal Quran when it comes to the comfort and weight of LBW infants.Methods: This study used a clinical randomized controlled trial design involving 52 low birth weight infants. The infants were randomly assigned to either the intervention group (n=26) or the control (n=26). The intervention of Murottal Quran was given using a speaker 4 times a day for 20 minutes every 3 hours. This intervention was conducted for three days.Results: The results of this study show that there is a significant difference in the comfort of  low birth weight infants after Murottal Qur’an on the first, second, and third days between the intervention and control groups (p=0.014; <0.001; <0.001). There was no significant difference in the weight between the intervention and control groups in the first, second, and third days (p=0.481; 0.481; 0.464).Conclusion: The auditory stimuli of Murottal Quran can help to improve the comfort level of low birth weight infants during hospitalization. It can therefore be used as a supportive therapy to facilitate low birth weight infant and premature infant development.


2021 ◽  
Vol 15 (10) ◽  
pp. 3423-3425
Author(s):  
Amna Najam ◽  
Samreen Fakeer Muhammad ◽  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Maria Anwar

Objective: The aim of this study is to compare the fetal and maternal outcomes in between asymptomatic and symptomatic COVID positive pregnant women. Study Design: Retrospective cohort study Place and Duration: The study was conducted at Gynae and Obs department of Sandeman Provincial Hospital, Quetta for duration of six months from November 2020 to April 2021. Methods: One hundred and ten pregnant women with ages 18-45 years had corona virus disease were presented. Informed written consent was taken from all patients for detailed demographics. COVID -19 was diagnosed by PCR. 55 patients had symptoms of coronavirus were included in group A and 55 patients did not show symptoms were included in group B. Frequency of pre-eclampsia, gestational diabetes mellitus and post-partum haemorrhage were calculated. Maternal adverse outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor, hypertensive disorder) were calculated among both groups. Fetal outcomes perinatal mortality, Low birth weight, Low Apgar score and NICU admission were observed. SPSS 20.0 version was used to analyze all data. Results: Mean age of the patients in group A was 28.47±3.18 years with mean BMI 24.03±5.24 Kg/m2 and in group B mean age was 27.99±4.17 years with mean BMI 24.44±6.41 Kg/m2. Maternal outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor,) in symptomatic group were significantly higher than that of asymptomatic group. Fetal outcomes, perinatal mortality in group A 9 (16.4%) and in group B was 5 (9.1%), low birth weight in group A was among 21 (38.2%) and in group B was 10 (18.2%), low apgar score in group A was 11 (20%) and in group B was 8 (14.4%), 15 (27.3%) in group A went to NICU admission and 3 (5.5%) patient in group II admitted to NICU. Conclusion: In this study we concluded that adverse outcomes among symptomatic COVID pregnant women were higher than that of asymptomatic coronavirus pregnant women in terms maternal and perinatal outcomes. Keywords: Pregnant women, Coronavirus, Symptomatic, Asymptomatic, Adverse Outcomes


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yi Jiang ◽  
Weihua Pan ◽  
Wenjie Wu ◽  
Weipeng Wang ◽  
Suna Sun ◽  
...  

Abstract Background In the last century, meconium peritonitis(MP)was once a highly fatal gastrointestinal. disease With the development of fetal radiological technology, abnormal signs, such as pseudocysts, can. be detected during the fetal period so that more patients can be diagnosed prenatally and receive surgery. in the early stage of life. The survival rate of MP has increased up to 80% in recent years. According to. a review of the treatment and outcomes of patients diagnosed with MP, we evaluated the influence of. early operation on survival rate and discussed the risk factors of prognosis. Methods We collected 79 cases of patients diagnosed with MP who were treated in our department. from October 2001 to December 2017. They were divided into 2 groups. Patients in group A were born. in our hospital. Patients in group B were born in a local hospital with suspicion of MP and then transferred. to our department. Results The birth weight (BW) and gestational age (GA) of patients were higher in group A than in. group B. There was no significant difference in the proportion of premature and low birth weight (LBW). patients between the two groups (p = 0.422, p = 0.970). Their age at the time of surgery was younger in. group A than in group B (1.4 ± 2.0 vs. 6.9 ± 14.9, p < 0.001). The overall survival rate of group A was higher. than that of group B (95.0% vs. 79.5%, p = 0.038). The prognosis of premature patients was worse than. that of full-term infants for both groups (p = 0.012). Conclusions Prematurity is a significant risk factor related to death for MP patients. The survival rate. of MP patients can be improved by early operation during the neonatal period.


Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1256 ◽  
Author(s):  
Stefan Kurath-Koller ◽  
Charlotte Neumann ◽  
Christine Moissl-Eichinger ◽  
Raimund Kraschl ◽  
Claudia Kanduth ◽  
...  

Background: It is unknown to what extent the microbiome of preterm infants is influenced by hospital regimens including the use of different probiotics when it comes to the prevention of necrotizing enterocolitis (NEC). Methods: Prospective controlled multicenter cohort study including very low birth weight infants from three neonatal intensive care units (NICUs) between October 2015 and March 2017. During this time span, stool was sampled every other day during the first two weeks and samples were subjected to amplicon-based microbiome analyses. Out of these, seventeen negative controls were processed (German Registry of Clinical Trials (No.: DRKS00009290)). Results: The groups (3 × 18 infants) showed no statistically significant difference regarding gestational age, birth weight, APGAR scores and oxygen demand. 2029 different taxa were detected, including Enterococcus and Staphylococcus, as well as the probiotic genera Lactobacillus and Bifidobacterium predominating. The bacterial load was found to increase earlier on when probiotics were used. Without probiotics administration, Lactobacillus and Bifidobacterium contributed only marginally to the fecal microbiome. Some infants did not respond to probiotic administration. The samples from all centers participating reached a very similar diversity after two weeks while the microbiome samples from all three centers clustered significantly yet varied from each other. Conclusion: Probiotics proved to be safe and initiated an earlier increase of bacterial load (with marked individual divergences), which might play a crucial role in the prevention of neonatal morbidities. Meconium was found not to be free of bacterial DNA, and oral antibiotics did not influence the fecal microbiome development negatively, and hospital regimes led to a center-specific, distinct cluster formation.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Maryam Sabbaghchi ◽  
Rostam Jalali ◽  
Masoud Mohammadi

Background. Low birth weight is a significant index for survival, intrauterine growth, and mortality in infants. Thus, this study is aimed at determining the prevalence of low birth weight in Iranian infants through a systematic review and meta-analysis. Methods. This study was performed by meta-analysis from January 2000 to December 2019. The studies relevant to the topic have been obtained through search in databases of Scopus, ScienceDirect, SID, Magiran, Barakat Knowledge Network System, Medline (PubMed), and Google Scholar. Heterogeneity of the studies has been assessed by the I 2 index, and data analysis was done using Comprehensive Meta-Analysis software. Results. By investigating 14 articles and 93924 infants, the total prevalence of low birth weight in infants in Iran was achieved at 8.5% (95% CI: 7.3-9.9%) according to the meta-analysis; the most prevalence of low birth weight was in infants in Hamedan at 19.1% (95% CI: 21.2-17.2%) in 2007, and the lowest prevalence of low birth weight was in infants in Tonekabon at 4.2% (95% CI: 3.4-5.2%) in 2005, and also, by increasing the sample size, the prevalence of low birth weight increases, by which the difference is statistically significant ( P < 0.05 ). Conclusion. Due to the high prevalence of low birth weight in infants in Iran, health policy-makers must take effective attempts in order to reduce it in infants.


Jurnal NERS ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 111
Author(s):  
Desriati Devi ◽  
Yeni Rustina ◽  
Defi Efendi

Introduction: Low birth weight (LBW) infants who have been hospitalized are exposed to various conditions that provoke discomfort, which could trigger a stress response and growth disorders. This study aimed to identify the effects of auditory stimuli from Murottal Quran when it comes to the comfort and weight of LBW infants.Methods: This study used a clinical randomized controlled trial design involving 52 low birth weight infants. The infants were randomly assigned to either the intervention group (n=26) or the control (n=26). The intervention of Murottal Quran was given using a speaker 4 times a day for 20 minutes every 3 hours. This intervention was conducted for three days.Results: The results of this study show that there is a significant difference in the comfort of  low birth weight infants after Murottal Qur’an on the first, second, and third days between the intervention and control groups (p=0.014; <0.001; <0.001). There was no significant difference in the weight between the intervention and control groups in the first, second, and third days (p=0.481; 0.481; 0.464).Conclusion: The auditory stimuli of Murottal Quran can help to improve the comfort level of low birth weight infants during hospitalization. It can therefore be used as a supportive therapy to facilitate low birth weight infant and premature infant development.


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