scholarly journals The Effect of Periodic Ketogenic Diet on Newly Diagnosed Overweight or Obese Patients with Type 2 Diabetes

2020 ◽  
Author(s):  
Sumei Li ◽  
Guoxin Lin ◽  
Jinxing Chen ◽  
Zhenxin Chen ◽  
Feipeng Xu ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Ketogenic Diet ◽  
Blood Lipid ◽  
Diet Group ◽  
Control Group ◽  
Obese Patients ◽  
Newly Diagnosed ◽  
Diet Control

Abstract BackgroundTo observe the effect of periodic ketogenic diet intervention on newly diagnosed overweight or obese patients with type 2 diabetes.Methods60 overweight or obese T2DM patients were randomly divided into ketogenic diet group and diabetes diet control group, 30 patients in each group. The changes and significance of blood glucose, blood lipid, body weight, insulin, uric acid and other indicators before and after the intervention were observed.ResultsThe Weight, BMI, Waist, TG, TC, LDL, HDL, FBG, FINS, HbA1c of the two groups decreased significantly compared with the previous period (P < 0.05). However, UA showed an increasing trend in the ketogenic diet group and no significant change in UA in the diabetic diet control group (P > 0.05). Long-term adherence to the ketogenic diet was not as strong as that of the diabetic diet.ConclusionThe phased-ketogenic diet can control not only weight but also blood glucose and blood lipid in patients with overweight or obese T2DM. But long-term persistence is difficult.

scholarly journals The Effect of Periodic Ketogenic Diet on Newly Diagnosed Overweight or Obese Patients with Type 2 Diabetes

2020 ◽  
Author(s):  
Sumei Li ◽  
Guoxin Lin ◽  
Jinxing Chen ◽  
Zhenxin Chen ◽  
Feipeng Xu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Ketogenic Diet ◽  
Blood Lipid ◽  
Diet Group ◽  
Control Group ◽  
Obese Patients ◽  
Newly Diagnosed ◽  
Diet Control

Abstract Background To observe the effect of periodic ketogenic diet intervention on newly diagnosed overweight or obese patients with type 2 diabetes.Methods 60 overweight or obese T2DM patients were randomly divided into ketogenic diet group and diabetes diet control group, 30 patients in each group. The changes and significance of blood glucose, blood lipid, body weight, insulin, uric acid and other indicators before and after the intervention were observed.Results The Weight, BMI, Waist, TG, TC, LDL, HDL, FBG, FINS, HbA1c of the two groups decreased significantly compared with the previous period (P < 0.05). However, UA showed an increasing trend in the ketogenic diet group and no significant change in UA in the diabetic diet control group (P > 0.05). Long-term adherence to the ketogenic diet was not as strong as that of the diabetic diet.Conclusion The phased-ketogenic diet can control not only weight but also blood glucose and blood lipid in patients with overweight or obese T2DM. But long-term persistence is difficult.

Effect of finger millet (Eleusine coracana) buns supplementation on serum glucose and serum lipids level in type 2 diabetics

2017 ◽  
Vol 36 (04) ◽  
Author(s):  
Neha Tiwari ◽  
D. M. Shere
Keyword(s):  
Blood Glucose ◽  
Finger Millet ◽  
Serum Glucose ◽  
Eleusine Coracana ◽  
Control Group ◽  
Serum Triglycerides ◽  
Type 2 Diabetics ◽  
Experimental Group

The present study was conducted to show the long term effect of low glycemic index (GI) finger millet (Eleusine coracana) buns (GI = 36.57) on diabetics. This case control clinical trial was conducted on 30 type 2 diabetic subjects who were equally divided into 2 groups: experimental group (EG) and control group (CG). The EG patients were supplemented with four (200 g) finger millet flour buns for 60 days in comparison to control group without having any buns supplementation. All the samples supplemented to experimental group provided 23-25g of total dietary fibre per day. The metabolic parameters studied were serum glucose, serum cholesterol, serum LDL, serum HDL, serum triglycerides and serum VLDL. Blood glucose levels (both fasting and post prandial) and lipid profile (at fasting) of the subjects were assessed at baseline and after 60 days of supplementation. Significant reduction was recorded in fasting blood glucose (13.75%), post prandial blood glucose (14.43%), serum cholesterol (4.41%) and serum LDL (11.22%) and also a decrease in serum triglycerides (5.11%) and VLDL (4.74%). Serum HDL increased significantly by 14.98 per cent. Thus, it is concluded that finger millet as a low GI food product leads to modest improvement in long-term glycemic and lipidemic control in type 2 diabetics.

scholarly journals Long-term effect of metformin on blood glucose control in non-obese patients with type 2 diabetes mellitus

2010 ◽  
Vol 7 (1) ◽  
pp. 83 ◽  
Author(s):  
Hiroyuki Ito ◽  
Hidenori Ishida ◽  
Yuichiro Takeuchi ◽  
Shinichi Antoku ◽  
Mariko Abe ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Control ◽  
Term Effect ◽  
Obese Patients ◽  
Long Term Effect

scholarly journals Individualized Meal Replacement Therapy Improves Clinically Relevant Long-Term Glycemic Control in Poorly Controlled Type 2 Diabetes Patients

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1022 ◽  
Author(s):  
Kerstin Kempf ◽  
Martin Röhling ◽  
Katja Niedermeier ◽  
Babette Gärtner ◽  
Stephan Martin
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Glycemic Control ◽  
Control Group ◽  
Meal Replacement ◽  
Low Carbohydrate ◽  
Meal Replacements

Background Formula diets can improve glycemic control or can even induce remission in type 2 diabetes. We hypothesized that especially an individualized intense meal replacement by a low-carbohydrate formula diet with accompanied self-monitoring of blood glucose (SMBG) contributes to long-term improvements in HbA1c, weight, and cardiometabolic risk factors in poorly controlled type 2 diabetes. Methods Type 2 diabetes patients were randomized into either a moderate group (M-group) with two meal replacements/day (n = 160) or a stringent group (S-group) with three meal replacements/day (n = 149) during the first week of intervention (1300–1500 kcal/day). Subsequently, both groups reintroduced a low-carbohydrate lunch based on individual adaption due to SMBG in weeks 2–4. After week 4, breakfast was reintroduced until week 12. During the follow-up period, all of the participants were asked to continue replacing one meal per day until the 52-weeks follow-up. Additionally, an observational control group (n = 100) remained in routine care. Parameters were compared at baseline, after 12 and 52 weeks within and between all of the groups. Results 321 participants (83%) completed the acute meal replacement phase after 12 weeks and 279 participants (72%) the whole intervention after 52 weeks. Both intervention groups achieved improvements in HbA1c, fasting blood glucose, blood pressure, and weight (all p < 0.001) within 12 weeks. However, these results were not significantly different between both of the intervention groups. The estimated treatment difference in HbA1c reduction was (mean (95% confidence interval [CI]) -0.10% with 95% CI [−0.40; 0.21] also (p > 0.05) (S-group vs. M-group) not statistically different after 12 weeks. However, only the S-group showed a clinically relevant improvement in HbA1c of −0.81% [−1.06; −0.55] (p < 0.001) after 52 weeks of follow-up, whereas HbA1c was not statistically different between the M- and control group. Conclusion Individualized meal replacement with SMBG demonstrated beneficial effects on HbA1c and cardiometabolic parameters in type 2 diabetes. Furthermore, the initiation of a weight loss program with one week of full meal replacement (three meals per day) resulted in a clinically relevant long-term HbA1c reduction, as compared to an observational control group that had standard care.

scholarly journals EFFECT OF SGLT-2 INHIBITOR ON BONE TURNOVER IN OVERWEIGHT AND OBESE PATIENTS WITH TYPE 2 DIABETES

2021 ◽  
Author(s):  
WEN-TAO LV ◽  
QIU-MEI ZHANG ◽  
XIANG-WEN MENG
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Bone Turnover ◽  
Hypoglycemic Agents ◽  
Control Group ◽  
Obese Patients ◽  
Oral Hypoglycemic Agents ◽  
Significant Difference ◽  
Experimental Group

To investigate the effect of sodium glucose cotransporter 2 inhibitor (SGLT-2I) on bone turnover markers in overweight and obese patients with type 2 diabetes mellitus. Methods: according to the criteria of selection and exclusion, 42 patients with overweight and obese type 2 diabetes (BMI≥25kg/m2) were selected from October 2019 to May 2020. The patients were randomly divided into experimental group and control group, there were 18 cases in the experimental group and 24 cases in the control group. The experimental group was treated with SGLT-2I, and other oral hypoglycemic agents (or insulin) were added according to the blood glucose situation. The control group received oral hypoglycemic agents (non-SGLT-2I) and/or insulin and/or glucagon-like peptide-1 receptor agonist (GLP-1 RA). Every 28 days of follow-up, medication regimen was adjusted according to blood glucose and adverse reactions of patients. Fasting venous serum of the patients was collected at the beginning and again 24 weeks later and the levels of PINP and β-CTX were detected uniformly. SPSS 21.0 was used to compare the changes of clinical indexes before and after the treatment. Results: 1. In the experimental group, PINP, HbA1c, FPG and BMI decreased (p<0.05). 2. In the control group, HbA1c, FPG and PINP decreased (p<0.05). 3. Comparison between groups after 24 weeks of treatment: there was significant difference in BMI (p<0.05).

scholarly journals Long-Term Assessment of Rehabilitation Treatment of Sports through Artificial Intelligence Research

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Chaofan Zeng ◽  
Ying Huang ◽  
Longer Yu ◽  
Qingmei Zeng ◽  
Bijun Wang ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Blood Pressure ◽  
Blood Glucose ◽  
Health Management ◽  
Blood Lipid ◽  
Practical Significance ◽  
Control Group ◽  
Management Service ◽  
Observation Group

Background. Artificial intelligence (AI) technology has been incorporated into all walks of life, especially the integration of machine learning and health management has achieved very significant progress and results. It is very necessary to analyze personalized sports health management services and long-term assessment of health issues in the era of AI. Methods. This paper explores AI + personalized sports management service system design ideas, system operation process, management stage design, taking common chronic diseases, and diabetes as examples. 150 patients were divided into an observation group and a control group, and the blood glucose, blood pressure, blood lipid, and knowledge awareness rate were compared. Results. The blood glucose, blood pressure, and blood lipid levels of the observation group all reduced, and the awareness rate of diabetes knowledge increased, which proved that the AI research has great value in sports rehabilitation research coupled with long term health assessment and is worth further research. Conclusion. The AI research proposed in this paper is of far-reaching practical significance in helping the transformation and upgrading of the sports health management service industry, promoting the innovative development of sports health management service supply, and promoting national fitness and national health.

scholarly journals Clinical Observation of Miglitol Combined with Insulin in Newly Diagnosed Type 2 Diabetes Mellitus

2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Shengting Huang ◽  
Shiying Huang
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Insulin Glargine ◽  
Adverse Reactions ◽  
Fasting Blood Glucose ◽  
Postprandial Blood Glucose ◽  
Control Group ◽  
Observation Group ◽  
Newly Diagnosed

Objective — To study the clinical efficacy of miglitol combined with insulin in the treatment of newly diagnosed type 2 diabetes mellitus. Methods — 96 newly diagnosed type 2 diabetes patients admitted to our hospital from January 2021 to September 2021 were selected as the subjects of this study. They were randomly divided into two groups by drawing lots. The control group was treated with acarbose combined with insulin glargine, and the observation group was treated with miglitol combined with insulin glargine. Fasting blood glucose, 2h postprandial blood glucose, glycosylated hemoglobin (HbA1c), blood glucose compliance time, occurrence of adverse reactions and quality of life score of 2 groups were measured before and after treatment. Results — After treatment, fasting blood glucose, 2h postprandial blood glucose and HbA1c in both groups were lower than before (P < 0.05), and there was no statistical significance in the difference between the two groups and the time of blood glucose reaching the standard (P > 0.05). The incidence of adverse reactions in observation group was lower than that in control group, and the quality of life score in observation group was better than that in control group (P < 0.05). Conclusions — Miglitol or acarbose combined with insulin glargine can effectively control blood glucose in patients with newly diagnosed type 2 diabetes, but miglitol combined with insulin glargine has fewer adverse reactions, which can be used as the first choice for clinical treatment of newly diagnosed type 2 diabetes.

scholarly journals Long-term effects of daily postprandial physical activity on blood glucose: a randomized controlled trial

2017 ◽  
Vol 42 (4) ◽  
pp. 430-437
Author(s):  
Håvard Nygaard ◽  
Eirik Grindaker ◽  
Bent Ronny Rønnestad ◽  
Gerd Holmboe-Ottesen ◽  
Arne Torbjørn Høstmark
Keyword(s):  
Physical Activity ◽  
Blood Glucose ◽  
High Risk ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Long Term Effects ◽  
Post Test

Previous studies have shown that a bout of moderate or light postprandial physical activity effectively blunts the postprandial increase in blood glucose. The objective of this study was to test whether regular light postprandial physical activity can improve glycemia in persons with hyperglycemia or with a high risk of hyperglycemia. We randomized 56 participants to an intervention or a control group. They were diagnosed as hyperglycemic, not using antidiabetics, or were categorized as high-risk individuals for type 2 diabetes. The intervention group was instructed to undertake a minimum 30 min of daily light physical activity, starting a maximum of 30 min after a meal in addition to their usual physical activity for 12 weeks. The control group maintained their usual lifestyle. Blood samples were taken pre- and post-test. Forty participants completed the study and are included in the results. The self-reported increase in daily physical activity from before to within the study period was higher in the intervention group compared with control (41 ± 25 vs. 2 ± 16 min, p < 0.001). Activity diaries and accelerometer recordings supported this observation. The activity in the intervention group started earlier after the last meal compared with control (30 ± 13 vs. 100 ± 57 min, p = 0.001). There were no within- or between-group differences in any glycemic variable from pre- to post-test. In conclusion, the present study does not seem to support the notion that regular light postprandial physical activity improves blood glucose in the long term in persons with hyperglycemia or with high risk of hyperglycemia.

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