scholarly journals Potentially Inappropriate Prescribing in a Falls Clinic Using the STOPP & START Criteria

Author(s):  
Rosalind Chiam ◽  
Nor'izzati Saedon ◽  
Hui Min Khor ◽  
Sukanya A/P Subramaniam ◽  
Siti Sakinah binti Mohmad Nasir ◽  
...  

Abstract Background Potentially inappropriate prescribing which may lead to adverse drug events and linked to polypharmacy is becoming increasingly common in older patients. Objective This study applied the STOPP/START criteria to a clinical registry to determine the burden and profile of potentially inappropriate prescribing among patients attending a falls clinic. Setting University of Malaya Medical Centre Falls Clinic Method Data of individuals aged ≥ 65 years referred to the falls and syncope clinic were extracted from the falls registry. Potentially inappropriate prescribing was determined with the STOPP/START version 2 criteria. The relationship between potentially inappropriate prescribing with polypharmacy (≥ 5 medications), comorbidities and clinical variables were determined using Pearson’s chi-square and potential confounders adjusted for with multivariate regression. Main outcome measure Potentially inappropriate medicines and/or omitted medicines using STOPP/START criteria Results Data from 421 individuals, aged 77.8 ± 6.7 years and 53.4% women, were included. Potentially inappropriate prescribing was present in 311 (74%). Potentially inappropriate medicines use accounted for 84.6% of the 325 prescriptions. 361/659 instances (54.8%) were falls-risk-increasing drugs, with vasodilators (49.3%) being the main potentially inappropriate medicine identified. Of the 177/421 with polypharmacy, 169/177 (95.5%) were exposed to ≥ one potentially inappropriate medicine. 129 instances of potentially omitted medicines were observed in 109 prescriptions (25.9%). Conclusion STOPP/START criteria are useful to identify potentially inappropriate prescribing at the falls and syncope clinic. This finding has important implications for medication review strategies at falls clinic. Future research should determine whether identifying potentially inappropriate prescribing may reduce adverse falls outcomes among patients in this setting.

Author(s):  
Akram Farhat ◽  
Alice Panchaud ◽  
Amal Al-Hajje ◽  
Pierre-Olivier Lang ◽  
Chantal Csajka

Abstract Purpose Potentially inappropriate prescribing (PIP) is a source of preventable adverse drug events. The objective of this study was a comparative analysis (quantitative and qualitative) between two tools used to detect PIP, PIM-Check and STOPP/START. Methods First, a qualitative analysis (QAC) was conducted to evaluate the concordance between the criteria, which constitute PIM-Check and the gold standard STOPP/START. Second, a retrospective comparative and observational study was performed on the list of treatment at the admission of 50 older patients hospitalized in an acute geriatric ward of a university hospital in Switzerland in 2016 using both tools. Results The QAC has shown that 50% (57 criteria) of STOPP/START criteria are fully or partially concordant with those of PIM-Check. The retrospective study was performed on 50 patients aged 87 years, suffering from 5 co-morbidities (min–max 1–11) and treated by of 8 drugs (min–max 2–16), as medians. The prevalence of the detected PIP was 80% by PIM-Check and 90% by STOPP/START. Medication review shows that 4.2 PIP per patient were detected by PIM-Check and 3.5 PIP by STOPP/START among which 1.9 PIP was commonly detected by both tools, as means. PIM-Check detected more PIP related to cardiology, angiology, nephrology, and endocrinology in older patients but missed the PIP related to geriatric syndromes (e.g., fall, dementia, Alzheimer) detected by STOPP/START. Conclusions By using PIM-Check in geriatric settings, some PIP will not be detected. It is considered as a limitation for this tool in this frail population but brings a certain complementarity in other areas of therapy not covered by STOPP/START.


Author(s):  
James T. Hubbell ◽  
Kathleen M. Heide ◽  
Norair Khachatryan

Given recent U.S. Supreme Court rulings regarding the constitutionality of juveniles who received mandated life sentences, questions have arisen in the field of criminology regarding how these offenders will adjust if someday released. Risk scores were calculated for 59 male juvenile homicide offenders (JHOs) based upon the eight domains in the Youth Level of Supervision/Case Management Inventory (YLS/CMI) and used to examine recidivism among the 48 JHOs who were released. Sample subjects were charged as adults for murder and attempted murder in the 1980s, convicted, and sentenced to adult prison. Chi-square analyses were used to assess the relationship between risk score category and two measures of recidivism, which were general arrests and violent offenses. Results indicated risk scores failed to predict both general and violent recidivism. Implications of the findings and directions for future research are discussed.


2019 ◽  
Vol 39 (1) ◽  
pp. 92-94 ◽  
Author(s):  
Anunciación Gonzalez-Lopez ◽  
Alvaro Nava-Rebollo ◽  
Angel Chocarro-Martinez ◽  
Beatriz Andres-Martin ◽  
Henar Santana-Zapatero ◽  
...  

2021 ◽  
Vol 9 (Spl-1- GCSGD_2020) ◽  
pp. S187-S195
Author(s):  
Lai Yi Ying ◽  
◽  
Ambusam Subramaniam ◽  

The current study aimed to examine the association between music and motivation to do exercise among university students in Nilai, Negeri Sembilan, Malaysia. The demographics data, use of music during exercise, preferred type of music, and criteria to select music were assessed by a validated self-administered questionnaire. The motivation towards exercises was evaluated using the Behavioural Regulations in Exercise Questionnaire (BREQ-3) while the level of physical activity was assessed by Godin-Leisure Time Exercise Questionnaire (LTEQ). The demographics information, use of music during exercise, preferred type of music, and criteria to choose music were tabulated using descriptive statistics. A point-biserial correlation was used to analyze the relationship between music and motivation to do exercise while chi-square was utilized to determine the association between the use of music during exercise and physical activity level. The results of the current study showed that 80.3% of the participants listen to music during exercise. Energetic and rhythmic was the preferred type of music for exercise. Tempo/ speed/ bpm was the most popular factor to be considered during the exercise. Most of the participants prefer to listen to an individual music player during exercise rather than an open audio system.. Listening to music during exercise shown significant correlation with a motivation (p=0.006), external regulation (p=0.014), identified regulation (p=0.006), integrated regulation (p=0.002) and intrinsic regulation (p=0.015). There was a significant association between the use of music during exercise and physical activity level (p=0.003) in this study. Future research that involves the type of exercise performed with the music is encouraged to explore the significance of music as a motivational tool in exercise.


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Marisa Baré ◽  
Marina Lleal ◽  
Sara Ortonobes ◽  
Maria Queralt Gorgas ◽  
Daniel Sevilla-Sánchez ◽  
...  

Abstract Objectives The objectives of the present analyses are to estimate the frequency of potentially inappropriate prescribing (PIP) at admission according to STOPP/START criteria version 2 in older patients hospitalised due to chronic disease exacerbation as well as to identify risk factors associated to the most frequent active principles as potentially inappropriate medications (PIMs). Methods A multicentre, prospective cohort study including older patients (≥65) hospitalized due to chronic disease exacerbation at the internal medicine or geriatric services of 5 hospitals in Spain between September 2016 and December 2018 was conducted. Demographic and clinical data was collected, and a medication review process using STOPP/START criteria version 2 was performed, considering both PIMs and potential prescribing omissions (PPOs). Primary outcome was defined as the presence of any most frequent principles as PIMs, and secondary outcomes were the frequency of any PIM and PPO. Descriptive and bivariate analyses were conducted on all outcomes and multilevel logistic regression analysis, stratified by participating centre, was performed on the primary outcome. Results A total of 740 patients were included (mean age 84.1, 53.2% females), 93.8% of them presenting polypharmacy, with a median of 10 chronic prescriptions. Among all, 603 (81.5%) patients presented at least one PIP, 542 (73.2%) any PIM and 263 (35.5%) any PPO. Drugs prescribed without an evidence-based clinical indication were the most frequent PIM (33.8% of patients); vitamin D supplement in older people who are housebound or experiencing falls or with osteopenia was the most frequent PPO (10.3%). The most frequent active principles as PIMs were proton pump inhibitors (PPIs) and benzodiazepines (BZDs), present in 345 (46.6%) patients. This outcome was found significantly associated with age, polypharmacy and essential tremor in an explanatory model with 71% AUC. Conclusions PIMs at admission are highly prevalent in these patients, especially those involving PPIs or BZDs, which affected almost half of the patients. Therefore, these drugs may be considered as the starting point for medication review and deprescription. Trial registration number NCT02830425


2019 ◽  
Vol 34 (20) ◽  
pp. 4225-4253
Author(s):  
Billie-Jo Grant ◽  
Ryan T. Shields ◽  
Joan Tabachnick ◽  
Jenny Coleman

This study examines data from Stop It Now!’s Helpline in the United States primarily over a 5-year, 3-month period and offers insights into the needs of individuals and families confronting issues related to child sexual abuse (CSA). Stop It Now!’s Helpline serves the global community by providing support, information, and guidance to those in need, such as helping to identify and respond to warning signs of sexually abusive behaviors in adults, adolescents, or children. More than 7,000 ( N = 7,122) nonidentifiable user records are the subject of this inquiry and reflect individuals who contacted the Helpline between December 1, 2012, and March 7, 2018. The article also places this analysis in a larger context through an overview that includes total user count of this service since its inception in 1995 ( N = 21,030). Descriptive statistics revealed that the majority of Helpline users identified as bystanders, family members, or friends/acquaintances of an individual at risk to abuse. The majority of users knew both the person at risk to abuse (adult or youth) and the child at risk of being abused. Twelve percent of users had questions or concerns about their own feelings and/or behaviors that were or could be putting a child at risk of sexual abuse. Chi-square tests examined the relationship between Helpline contact type, level of assessment, and gender. Findings provide insights into this hidden population of individuals at risk to abuse, those who have abused, as well as their friends and families who are seeking support. Study findings also reinforce the importance of CSA prevention helplines that focus on reducing the isolation and secrecy that creates conditions which make children more vulnerable to abuse. Implications for future research and prevention programming are also discussed.


Author(s):  
Syamala Devi Bhoganadam ◽  
Dasaraju Srinivasa Rao ◽  
A. Mahesh Reddy ◽  
S. K. Malina

Employees are considered as real assets for any organization in the modern economy because modern organizations believe that due to globalization employee retention is a major problem hence employees are treated as real assets for the organizations. Once employees are satisfied with the organization then employee retention takes place. Employee satisfaction is linked with employee job satisfaction. So this study concentrates on factors determining employee job satisfaction at Balaji Agencies and Industries. The main objective of the study is to determine the factors influencing job satisfaction of employees at Balaji Agencies and Industries. The other objectives were to calculate the Job Satisfaction Index (JSI) and to find the relationship between the personal factors and job satisfaction of employees. Data were collected from 53 employees at Balaji Agencies and Industries at Nellore. Data were analyzed using chi square analysis. The findings of the study reveal that there is no relationship between age, gender, educational qualification of employee and experience to the job satisfaction. It may be in relation with some other factors which are included in the study considered for scope of future research.


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