Investigation of Disease Spectrum and Analysis of Risk Factor for Digestive System Diseases of Chinese Army During a Field Training on The Midland of China

2021 ◽  
Author(s):  
Guanjun Zhang ◽  
Mingyang Li ◽  
Fan Lin ◽  
Yizhe Zhang ◽  
Haohui Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Military Service ◽  
Digestive System ◽  
Treatment Strategies ◽  
Training Time ◽  
Field Training ◽  
System Disease ◽  
Disease Spectrum ◽  
Digestive Diseases ◽  
Digestive System Diseases

Abstract Objective To investigate the digestive disease spectrum of Chinese army servicemen during a field training on the midland and to analyze risk factors of diseases in order to discuss the relative prevention and treatment strategies.Methods Seven troops during a field training on the midland of China were randomly selected by using stratified cluster random sampling methods, all soldiers in that received a questionnaire survey, and then we collected all questionnaires and summarized the soldiers’ digestive system disease spectrum, and discussed risk factors for diseases.Results 3055 valid questionnaires were finally collected,896 soldiers had digestive symptoms, and of all symptoms diarrhea was the most common,whose ratio was 29.3%; 507 soldiers suffered from digestive system diseases, including gastritis, enteritis,digestive ulcer, functional bowel disease, which were more common. By the logistic regression analysis, length of military service time, identity of army officer,length of a field training time,training pressure, chilled abdomen, and defiled food were possible risk factors for digestive diseases.Conclusions During a field training, a healthy and regular diet, the thermal outfit, appropriate decompression of negative emotions and reasonable training time may effectively decrease the risk of digestive diseases, so that to reduce attrition.

scholarly journals Investigation of Spectrum and Analysis of Risk Factor for Gastrointestinal Diseases of Chinese Army During a Field Training on the Midland of China in the New Era

2021 ◽  
Author(s):  
Guanjun Zhang ◽  
Mingyang Li ◽  
Fan Lin ◽  
Yizhe Zhang ◽  
Haohui Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Military Service ◽  
Digestive System ◽  
Treatment Strategies ◽  
Gastrointestinal Diseases ◽  
Training Time ◽  
Field Training ◽  
System Disease ◽  
Disease Spectrum ◽  
Digestive Diseases

Abstract Objective To investigate the digestive disease spectrum of Chinese army servicemen during a field training on the midland and to analyze risk factors of diseases in order to discuss the relative prevention and treatment strategies. Methods Seven troops during a field training on the midland of China were randomly selected by using stratified cluster random sampling methods,all soldiers in that received a questionnaire survey,and then we collected all questionnaires and summarized the soldiers’ digestive system disease spectrum, and discussed risk factors for diseases. Results 3055 valid questionnaires were finally collected,896 soldiers had digestive symptoms, and of all symptoms diarrhea was the most common,whose ratio was 29.3%; 507 soldiers suffered from digestive system diseases, including gastritis,enteritis,digestive ulcer,functional bowel disease, which were more common.By the logistic regression analysis, length of military service time,identity of army officer,length of a field training time,training pressure,chilled abdomen,and defiled food were possible risk factors for digestive diseases.Conclusions During a field training,a healthy and regular diet, the thermal outfit,appropriate decompression of negative emotions and reasonable training time may effectively decrease the risk of digestive diseases, so that to reduce attrition.

A Review of the Bioactive Ingredients, Pharmacological Functions and Mechanisms of Inonotus obliquus

2020 ◽  
Vol 17 ◽  
Author(s):  
Gulinigaer Anwaier ◽  
Cong Wen ◽  
Yi-ni Caoili ◽  
Rong Qi
Keyword(s):  
Digestive System ◽  
Treatment Strategies ◽  
Research Progress ◽  
Chemical Components ◽  
Separation And Purification ◽  
Active Components ◽  
Inonotus Obliquus ◽  
Global Issues ◽  
Medicinal Fungus ◽  
Digestive System Diseases

: As a medicinal fungus, Inonotus obliquus (IO) has been widely used in the treatment of cancer and digestive system diseases. Despite the progress that has been made in the studies of IO and its active compounds, their applications in other important clinical diseases, such as cardiovascular diseases, which are major global issues with limited treatment strategies, are seldom reported. This review summarizes the separation and purification methods of chemical components of IO, the advances in their applications, and research progress on the pharmacological effects and related mechanisms of IO in disease prevention. This review will help researchers and clinicians to further understand the pharmacological functions and mechanisms of IO and its active components, which may extend their medical applications in the prevention and treatment of other diseases in addition to tumors and digestive system diseases in the near future.

Risk factors for the development of digestive system diseases and prevalence of gastrointestinal symptoms in adolescents

2020 ◽  
pp. 41-47
Author(s):  
N. Komleva ◽  
V. Dolich ◽  
I. Zaikina ◽  
A. Danilov ◽  
A. Chekhonatskiy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Digestive System ◽  
Rating Scale ◽  
Gastrointestinal Symptoms ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Gastrointestinal Symptom Rating Scale ◽  
Digestive System Diseases

Digestive diseases are a very common pathology in children and adolescents. Analysis of risk factors for the development of diseases of the digestive system and prevalence of gastrointestinal symptoms in students of professional educational organizations are presented in the article. 265 students of vocational education organizations aged 15 to 18 years were examined. The study design was a one-time cross-sectional study (active screening). Standardized formalized maps were used (complaints, medical history, physical examination results, regime and nature of diets, lifestyle and social and economic aspects were studied) to assess frequency of gastrointestinal symptoms. Gastrointestinal Symptom Rating Scale (GSRS) – an internationally validated questionnaire for the study of quality of life developed by the Hassle Company (division of Astra) – was used to study gastrointestinal symptoms. Statistical data processing was carried out using «MS Excel 2002» program. The study was conducted in accordance with the requirements of bioethics, after receiving informed consent of adolescents and their parents. A number of adolescents who previously have been diagnosed with diseases of the digestive system are found; gastrointestinal symptoms are systematized and analyzed (symptom group according to the scales abdominal pain, reflux, dyspepsia diarrhoea, constipation) using the GSRS questionnaire; main risk factors for the development of digestive system diseases characteristic of adolescents are studied: (the nature and regime of diet, smoking, consumption of alcohol), awareness of students about the main factors of a healthy lifestyle were examined as results of the study. The results of the study must be taken into account when developing and implementing preventive and hygiene and educational measures that are aimed at maintaining health and improving the quality of life of the population and require an interdisciplinary approach.

scholarly journals CLINICAL AND LABORATORY MARKERS OF DIGESTIVE SYSTEM DISEASES IN HIV-INFECTED PATIENTS FOR FAMILY MEDICINE PRACTICE

2020 ◽  
Vol 73 (9) ◽  
pp. 1909-1914
Author(s):  
Olga A. Golubovska ◽  
Volodymyr I. Vysotskyi
Keyword(s):  
Antiretroviral Therapy ◽  
Hiv Infection ◽  
Digestive System ◽  
Gastrointestinal Disease ◽  
Medical Center ◽  
Clinical Stage ◽  
Blood Parameters ◽  
System Disease ◽  
Elevated Liver Enzymes ◽  
Digestive System Diseases

The aim: To identify clinical and laboratory signs of digestive system disease in HIV-infected patients for helping family physicians. Materials and methods: Research was conducted at five regional HIV / AIDS centers in Ukraine during 2017-2019. Randomly selected 342 adult HIV-infected patients were divided into two groups, with concomitant digestive system diseases and without concomitant digestive system disease. Statistical analysis was performed using the software package EZR 1.41 (Saitama Medical Center, Jichi Medical University, Japan). Results: The incidence of digestive system disease in patients with HIV clinical stages II, III and IV was significantly higher than in patients with HIV clinical stage I. Gastrointestinal disease was also significantly associated with the incidence of tuberculosis, candidiasis, kidney disease and HIV encephalopathy. Incidence of asthenic-vegetative and dyspeptic syndromes, weight loss, anemia and leukopenia, elevated liver enzymes, low CD4 counts and detectable viral load levels in patients on antiretroviral therapy were significantly more common in HIV-infected patients with gastrointestinal pathologies. HIV patients with digestive system disease significantly more often had changes to their therapy regiment, interruptions in treatment and more often experienced side effects. Conclusions: Digestive system disease becomes more common with the progression of HIV infection. Comorbidity of HIV infection and digestive system disease is characterized by changes in general clinical, biochemical and immunological blood parameters and patients with digestive system comorbidities more often have a poor virological response to antiretroviral therapy.

scholarly journals Conditional Cell Reprogramming in Modeling Digestive System Diseases

2021 ◽  
Vol 9 ◽  
Author(s):  
Ruihua Zhao ◽  
Rui Li ◽  
Tianqi An ◽  
Xuefeng Liu
Keyword(s):  
Digestive System ◽  
New Technologies ◽  
Profile Analysis ◽  
Human Cancer ◽  
Mouse Fibroblast ◽  
Precision Oncology ◽  
Rock Inhibitor ◽  
Treatment And Prevention ◽  
Digestive Diseases ◽  
Digestive System Diseases

Digestive diseases have become an important source of morbidity and mortality. The considerable financial and health burdens caused by digestive diseases confirm the importance of extensive research to better understand and treat these diseases. The development of reliable preclinical models is essential for understanding the pathogenesis of digestive diseases and developing treatment and prevention methods. However, traditional established cell lines and animal models still have many limitations in the study of the digestive system. Conditional reprogramming (CR) cell culture is a newly developed primary technology that uses irradiated Swiss-3T3-J2 mouse fibroblast cells and the Rho-associated kinase (ROCK) inhibitor Y-27632 to rapidly and efficiently generate many cells from diseased and normal tissues. CR cells (CRCs) can be reprogrammed to maintain a highly proliferative state and recapitulate the histological and genomic features of the original tissue. Moreover, after removing these conditions, the phenotype was completely reversible. Therefore, CR technology may represent an ideal model to study digestive system diseases, to test drug sensitivity, to perform gene profile analysis, and to undertake xenograft research and regenerative medicine. Indeed, together with organoid cultures, CR technology has been recognized as one of the key new technologies by NIH precision oncology and also used for NCI human cancer model initiatives (HCMI) program with ATCC. In this article, we review studies that use CR technology to conduct research on diseases of the digestive system.

Digestive system diseases associated with Turner's syndrome in 3 pediatric cases

2018 ◽  
Author(s):  
Lamia Gargouri ◽  
Faten Hadjkacem ◽  
Dorra Ghorbel ◽  
Faiza Safi ◽  
Manel Hsairi ◽  
...  
Keyword(s):  
Digestive System ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Digestive System Diseases

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH MYOCARDIAL INFARCTION AND CHRONIC INFLAMMATORY LUNG DISEASES

2020 ◽  
pp. 21-25
Author(s):  
Tupitsyn V.V. ◽  
Bataev Kh.M. ◽  
Men’shikova A.N. ◽  
Godina Z.N.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Digestive System ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Internal Organs ◽  
History Of

Relevance. Information about the cardiovascular diseases risk factors (CVD RF) for in men with chronic lung inflam-matory pathology (CLID) is contradictory and requires clarification. Aim. To evaluate the peculiarities of CVD RF in men under 60 years of age with CLID in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I myocardial infarction. Patients are divided into two age-comparable groups: I - the study group, with CLID - 142 patients; II - control, without it - 424 patients. A comparative analysis of the frequency of observation of the main and additional cardiovascular risk fac-tors in groups was performed. Results. In patients of the study group, more often than in the control group we observed: hereditary burden of is-chemic heart disease (40.8 and 31.6%, respectively; p = 0.0461) and arterial hypertension (54.2 and 44.6%; p = 0.0461), frequent colds (24.6 and 12.0%; p = 0.0003), a history of extrasystoles (19.7 and 12.7%; p = 0.04); chronic foci of infections of internal organs (75.4 and 29.5%; p˂0.0001), non-ulcer lesions of the digestive system (26.1 and 14.6%; p = 0.007), smoking (95.1 and 66.3%; p˂0.0001), MI in winter (40.8 and 25.9%; p = 0.006). Less commonly were observed: oral cavity infections (9.2 and 23.6%; p˂0.0001); hypodynamia (74.5 and 82.5%; p = 0.0358), over-weight (44.4 and 55.2%; p = 0.0136), a subjective relationship between the worsening of the course of coronary heart disease and the season of the year (43.7 and 55.2%; p = 0.0173) and MI - in the autumn (14.1 and 21.9%; p = 0.006) period. Conclusions. The structure of CVD RF in men under 60 years of age with CLID with MI is characterized by the pre-dominance of smoking, non-ulcer pathology of the digestive system, frequent pro-student diseases, meteorological dependence, a history of cardiac arrhythmias and foci of internal organ infections. It is advisable to use the listed factors when planning preventive measures in such patients.

Review of Chuna Manual Therapy for Adult Digestive System Disease

2018 ◽  
Vol 13 (2) ◽  
pp. 35-46
Author(s):  
Kyu-Jin Kim ◽  
Su-Cheol Choo ◽  
Jae-Won Lee ◽  
Eui-Hyoung Hwang
Keyword(s):  
Manual Therapy ◽  
Digestive System ◽  
System Disease

scholarly journals Overlap time is an independent risk factor of radiation pneumonitis for patients treated with simultaneous EGFR-TKI and thoracic radiotherapy

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Wenxiao Jia ◽  
Qianqian Gao ◽  
Min Wang ◽  
Ji Li ◽  
Wang Jing ◽  
...  
Keyword(s):  
Risk Factors ◽  
First Generation ◽  
Kinase Inhibitors ◽  
Radiation Pneumonitis ◽  
Cell Cancer ◽  
Treatment Strategies ◽  
Thoracic Radiotherapy ◽  
Ipsilateral Lung ◽  
Nsclc Patients ◽  
Egfr Tki

Abstract Background The exact rate and relevant risk factors of radiation pneumonitis (RP) for non-small-cell cancer (NSCLC) patients treated with the combination of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and thoracic radiotherapy have not been reported. Thus, this study aimed to investigate the rate and risk factors of RP for EGFR-positive NSCLC patients simultaneously treated with first-generation EGFR-TKI and TRT. Patients and methods We retrospectively evaluated NSCLC patients simultaneously treated with first-generation EGFR-TKI and thoracic radiotherapy between January 2012 and December 2019 at Shandong Cancer Hospital and Institute, Shandong, China. RP was diagnosed via computed tomography and was classified according to the Common Terminology Criteria for Adverse Events v5.0. The risk factors of RP were identified using uni- and multivariate analyses. Results Of the 67 patients included, 44.78% (30/67) developed grade ≥ 2 RP. Grade ≥ 2 RP occurred within a median of 3.48 (range 1.07–13.6) months. The EGFR-TKI icotinib, ipsilateral lung V30 > 34%, and overlap time of > 20 days between EGFR-TKI and thoracic radiotherapy were identified to be independent predictive factors of grade ≥ 2 RP. Conclusions Grade ≥ 2 RP is highly frequent in NSCLC patients simultaneous treated with first-generation EGFR-TKI and thoracic radiotherapy. Icotinib, ipsilateral lung V30 ≤ 34%, and overlap time of ≤ 20 days for EGFR-TKI and thoracic radiotherapy will be helpful to lower the risk of RP in these patients. The addition of thoracic radiotherapy should be cautious, and the treatment strategies can be optimized to reduce the rate of RP for patients treat with simultaneous EGFR-TKI and thoracic radiotherapy.

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