scholarly journals Effects of Short Term Omega-3 Supplementation on Body Composition, Food Intake, and Lipid Profile in Elite Athletes: A Double-blind Randomized Controlled Trial

2020 ◽  
Author(s):  
Sara Moradi ◽  
Mohamadreza Alivand ◽  
Yaser Khaje-Bishak ◽  
Mohamad Asghari-Jafarabadi ◽  
Maedeh Alipour ◽  
...  
Keyword(s):  
Body Composition ◽  
Placebo Group ◽  
Food Intake ◽  
Lipid Profile ◽  
Protein Intake ◽  
Elite Athletes ◽  
Controlled Trial ◽  
Fat Free Mass ◽  
Omega 3 ◽  
Anthropometric Measures

Abstract Background and Aims: animal studies consistently showed a key role for omega-3s in decreasing fat mass (FM). Also, previous studies have shown that increased omega-3 stimulates fat loss in individuals who experience obesity, diabetes and metabolic syndrome. However, it is not known whether omega-3 supplementation make similar effects in healthy individuals with low FM. This study aimed to investigate the effects of omega-3 on changes in body composition, food intake, and lipid profile in healthy athletes.Methods: 36 healthy men were allocated into either the supplement or the placebo group. Dietary intake assessed by the 24-hour food recall, before and after the intervention. Anthropometric measures, blood pressure, and lipid profile were measured at baseline and after 3-weeks.Results: The weight did not significantly change at the end of the study. Body fat percent decreased significantly at the end of the study in the omega-3 group (p= 0.003), but intergroup differences were not significant. FM decreased but fat free mass (FFM) increased in omega-3 groups (p<0.05). In Lipid profile indices just HDL-C increased (for omega-3 group p=0.001; for placebo group p=0.01; after adjustments p=0.78). Also, in the omega-3 group, energy intake (p=0.0007) and protein intake (p=0.04) after intervention increased, but after baseline adjustments they were not significant.Conclusion: 3-week omega-3 supplementation seems to be not effective in decreased FM, and increased HDL-C, and energy and protein intake in elite athletes. Further studies are recommended to determine the effect of different doses of omega-3 on adipose tissue in athletes with low FM.Clinical Trial Registration The present study was prospectively registered at the Iranian Registry of Clinical Studies on December 19, 2019 (ID: 20190625044008N1). https://en.irct.ir/trial/43332.

scholarly journals Effects of Short Term Omega-3 Supplementation on Body Composition, Food Intake, and Lipid Profile in Elite Athletes: A Double-Blind Randomized Controlled Trial.

2020 ◽  
pp. 1-15
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Food Intake ◽  
Lipid Profile ◽  
Controlled Trial ◽  
Fat Free Mass ◽  
Omega 3 ◽  
Double Blind ◽  
Clinical Trial Registration ◽  
Global Physical Activity Questionnaire

Abstract Previous studies consistently showed a key role for omega-3 fatty acids in decreasing fat mass (FM) in animal models. Also, increased omega-3 stimulates fat loss in individuals who experience obesity, diabetes and metabolic syndrome. However, it is not known whether omega-3 supplementation make similar effects in healthy individuals with low FM. This study aimed to investigate the effects of omega-3 on changes in body composition, food intake, and lipid profile in healthy athletes. In this double-blind placebo-controlled RCT, 36 healthy athletes were allocated into omega-3 or placebo groups. Physical activity (global physical activity questionnaire), dietary intake (24-h food recall), anthropometric status, and lipid profile were measured at baseline and after 3-weeks. 35 volunteers completed the trial. The weight did not significantly change at the end of the study. Body fat% decreased significantly at the end of the study in the omega-3 group (p=0.003), but intergroup differences were not significant (p=0.77). FM decreased and fat free mass (FFM) increased in omega-3 groups (p<0.05). HDL-C increased (omega-3 group p=0.001; placebo group p=0.01; after adjustment for baseline values p=0.78). Also, in the omega-3 group, energy intake (p=0.0007) and protein intake (p=0.04) increased after intervention, but after baseline adjustments they were not significant. In conclusion, 3-week omega-3 supplementation seems to be not effective in decreased FM, increased HDL-C, and energy and protein intakes in athletes. Further studies are recommended to determine the effect of different doses of omega-3 on adipose tissue and blood lipids in athletes with low FM. Clinical Trial Registration The present study was prospectively registered at the Iranian Registry of Clinical Studies on December 19, 2019 (ID: 20190625044008N1).

scholarly journals Raloxifene and body composition and muscle strength in postmenopausal women: a randomized, double-blind, placebo-controlled trial

2010 ◽  
Vol 162 (2) ◽  
pp. 371-376 ◽  
Author(s):  
Didy E Jacobsen ◽  
Monique M Samson ◽  
Marielle H Emmelot-Vonk ◽  
Harald J J Verhaar
Keyword(s):  
Body Composition ◽  
Placebo Group ◽  
Muscle Strength ◽  
Postmenopausal Women ◽  
Controlled Trial ◽  
Group Versus ◽  
The Body ◽  
Fat Free Mass ◽  
Double Blind ◽  
Double Blind Placebo

ObjectiveTo compare the effects of raloxifene and placebo on body composition and muscle strength.DesignRandomized, double-blind, placebo-controlled trial involving 198 healthy women aged 70 years or older conducted between July 2003 and January 2008 at the University Medical Centre, Utrecht, The Netherlands.MethodsParticipants were randomly assigned to receive raloxifene 60 mg or placebo daily for 12 months. Measurements were taken at baseline, 3, 6, and 12 months, and change from baseline was calculated. Main outcome measures were body composition (bioelectrical impedance analysis), muscle strength, and muscle power (maximum voluntary isometric knee extension strength, explosive leg extensor power, and handgrip strength).ResultsAt 12 months, the body composition of women taking raloxifene was significantly different from that of women taking placebo: fat-free mass (FFM) had increased by a mean of 0.83 (2.4) kg in the raloxifene group versus 0.03 (1.5) kg in the placebo group (P=0.05), and total body water had increased by a mean of 0.6 (1.8) litres in the raloxifene group versus a decrease of 0.06 (1.1) litres in the placebo group (P=0.02). Muscle strength and power were not significantly different.ConclusionRaloxifene significantly changed body composition (increased FFM; increased water content) compared with placebo in postmenopausal women.

scholarly journals The Effect of Protein Supplementation versus Carbohydrate Supplementation on Muscle Damage Markers and Soreness Following a 15-km Road Race: A Double-Blind Randomized Controlled Trial

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 858
Author(s):  
Dominique S. M. ten Haaf ◽  
Martin A. Flipsen ◽  
Astrid M. H. Horstman ◽  
Hans Timmerman ◽  
Monique A. H. Steegers ◽  
...  
Keyword(s):  
Placebo Group ◽  
Protein Intake ◽  
Muscle Soreness ◽  
Controlled Trial ◽  
Protein Supplementation ◽  
Group Differences ◽  
Double Blind ◽  
Carbohydrate Supplementation ◽  
Protein Group ◽  
Road Race

We assessed whether a protein supplementation protocol could attenuate running-induced muscle soreness and other muscle damage markers compared to iso-caloric placebo supplementation. A double-blind randomized controlled trial was performed among 323 recreational runners (age 44 ± 11 years, 56% men) participating in a 15-km road race. Participants received milk protein or carbohydrate supplementation, for three consecutive days post-race. Habitual protein intake was assessed using 24 h recalls. Race characteristics were determined and muscle soreness was assessed with the Brief Pain Inventory at baseline and 1–3 days post-race. In a subgroup (n = 149) muscle soreness was measured with a strain gauge algometer and creatine kinase (CK) and lactate dehydrogenase (LDH) concentrations were measured. At baseline, no group-differences were observed for habitual protein intake (protein group: 79.9 ± 26.5 g/d versus placebo group: 82.0 ± 26.8 g/d, p = 0.49) and muscle soreness (protein: 0.45 ± 1.08 versus placebo: 0.44 ± 1.14, p = 0.96). Subjects completed the race with a running speed of 12 ± 2 km/h. With the Intention-to-Treat analysis no between-group differences were observed in reported muscle soreness. With the per-protocol analysis, however, the protein group reported higher muscle soreness 24 h post-race compared to the placebo group (2.96 ± 2.27 versus 2.46 ± 2.38, p = 0.039) and a lower pressure muscle pain threshold in the protein group compared to the placebo group (71.8 ± 30.0 N versus 83.9 ± 27.9 N, p = 0.019). No differences were found in concentrations of CK and LDH post-race between groups. Post-exercise protein supplementation is not more preferable than carbohydrate supplementation to reduce muscle soreness or other damage markers in recreational athletes with mostly a sufficient baseline protein intake running a 15-km road race.

scholarly journals Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects

Endocrine ◽  
2021 ◽  
Author(s):  
Mariangela Rondanelli ◽  
Simone Perna ◽  
Zahra Ilyas ◽  
Gabriella Peroni ◽  
Philip Bazire ◽  
...  
Keyword(s):  
Body Composition ◽  
Visceral Fat ◽  
Mean Difference ◽  
Fat Free Mass ◽  
Class I ◽  
Omega 3 ◽  
Open Label ◽  
Metabolic Markers ◽  
High Loss ◽  
Class I Obesity

Abstract Purpose This study aims to evaluate the effects of a VLCKD combined with omega-3 supplementation (VLCKD diet only lasted for some weeks, and it was followed by a non-ketogenic LCD for the rest of the study period) on body composition, visceral fat, satiety hormones, inflammatory and metabolic markers. Methods It has been performed a pilot open label study lasted 90 days, in a cohort of 12 women with class I obesity aged 18 to 65 years. Data on body composition (evaluated by Dual X-Ray Absorptiometry—DXA), visceral fat, satiety hormones, inflammatory and metabolic markers were recorded. Results This study showed a body weight reduction mean difference over time of −13.7 kg and the waist circumference mean difference decrease of −13.3 cm. Also, the fat mass (FM) decreased—9.1 kg and visceral adipose tissue (VAT)—0.41 kg. No effects on fat-free mass (FFM) have been reported. Improvements were observed in the satiety hormones, with increased ghrelin and decreased leptin, and also in the metabolic profiles. Conclusions A VLCKD combined with omega-3 supplementation appears to be an effective strategy for promoting an high loss of FM with preservation of FFM in patients with class I obesity.

scholarly journals Obesity, smoking status and their relationships in selected population groups

2021 ◽  
pp. 291-299
Keyword(s):  
Body Composition ◽  
Lipid Profile ◽  
Fat Mass ◽  
Severe Obesity ◽  
Overweight And Obesity ◽  
Fat Free Mass ◽  
Chronic Obstructive ◽  
Average Value ◽  
Copd Patients ◽  
The Mean

Background. Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. Obesity is associated with many chronic diseases, including cardiovascular disease and diabetes, and recently the role of overweight and obesity in lung disease has received new interest. Chronic obstructive lung disease is the third-leading cause of death globally, and both obesity and diet appear to play roles in its pathophysiology. Cross-sectional studies have demonstrated an inverse association between obesity and the prevalence of chronic obstructive pulmonary disease (COPD). Objective. This study aims to evaluate the relationship between smoking, lipid profile and obesity (body composition changes) in a selected groups of population (30 non-smokers, 30 smokers and 60 COPD patients). Material and Methods. We evaluated fat mass, fat free mass, body mass index and lipid profile in a group of 120 randomly selected probands (60 COPD patients; 30 smokers without COPD; 30 non-smokers without COPD) to identify possible negative relationships of smoking to body composition. To the measurement of fat mass (FM) and fat free mass (FFM) was used a device Bodystat Quadscan 4000 (Bodystat Ltd, British Isles). The device works by using four-frequency bioelectrical impedance analysis. Laboratory parameters as total cholesterol (T-C), high-density cholesterol (HDL-C), low-density cholesterol (LDL-C) and triacylglycerols (TG) were investigated by automated clinical chemistry analyzer LISA 200th. The measured values were statistically processed and evaluated in a statistical program STATISTICA Cz. Version 7.1. (Kruskall-Wallis test). Results. A comparison of the mean fat mass we found statistically highly significant differences between the group of COPD patients and non-smokers (P <0.001) and insignificant differences (P ≥ 0.05) between the other groups of our experiment. A comparison of the mean fat mass values of all three groups of the experiment shows a steady increase in fat from non-smokers (17.66 ± 10.04 kg) to COPD patients with the highest mean value (25.08 ± 10.14 kg). In the group of COPD patients we recorded the lowest average value of FFM (51.76 ± 13.84 kg), in group of smokers the middle (56.06 ± 10.76 kg) and in non-smokers the highest average value of FFM (59.91 ± 9.90 kg) at relatively the same body weight in the groups. Based on calculated body mass index (BMI), we found in group of COPD patients overweight in 15 cases (25%), obesity in 7 patients (11.67%), severe obesity in 14 patients (23.3%) and morbid obesity in 2 patients (3.33%); in the group of smokers overweight in 16 cases (53.33%), obesity in 5 cases (16.6%) and severe obesity in 1 case (3.33%); in non-smokers we recording overweight in 14 cases (46.67%), obesity in 5 cases (16.67%) and severe obesity in 2 cases (6.67%). In the lipid profile of the monitored groups of probands, we observed statistically significant differences only for LDL cholesterol (LDL-C). There was a statistically significant difference (P <0.001) between the group with COPD and smokers, as well as between the group of smokers and non-smokers (P < 0.05). Conclusions. In the vast majority of patients with COPD, the lung damage that leads to COPD is caused by long-term cigarette smoking. The presence and absence of risk factors such as smoking, inappropriate lipid profile and obesity (amount of fat mass) in selected population groups were observed. Additional studies to explore both the quantitative and qualitative changes in body composition with disease process of COPD are required.

Comparing the effects of whey and casein supplementation on nutritional status and immune parameters in patients with chronic liver disease: a randomised double-blind controlled trial

2020 ◽  
pp. 1-12
Author(s):  
Y. G. G. Mizubuti ◽  
E. L. M. Vieira ◽  
T. A. Silva ◽  
M. O. d’Alessandro ◽  
S. V. Generoso ◽  
...  
Keyword(s):  
Body Composition ◽  
Liver Disease ◽  
Nutritional Status ◽  
Chronic Liver Disease ◽  
Neurotrophic Factor ◽  
Protein Intake ◽  
Controlled Trial ◽  
Protein Supplementation ◽  
Chronic Liver ◽  
Immune Parameters

Abstract Protein supplementation may be beneficial for patients with chronic liver disease (CLD). This study compared the effects of whey protein isolate (WP) and casein (CA) supplementation on nutritional status and immune parameters of CLD patients who were randomly assigned to take 20 g of WP or CA twice per d as a supplement for 15 d. Body composition, muscle functionality and plasmatic immunomarkers were assessed before and after supplementation. Patients were also classified according to the model for end-stage liver disease (MELD) into less (MELD < 15) and more (MELD ≥ 15) severe disease groups. Malnutrition, determined by the Subjective Global Assessment at baseline, was observed in 57·4 % and 54·2 % of patients in the WP and CA groups, respectively (P = 0·649). Protein intake was lower at baseline in the WP group than in the CA group (P = 0·035), with no difference after supplementation (P = 0·410). Both the WP and CA MELD < 15 groups increased protein intake after supplementation according to the intragroup analysis. No differences were observed in body composition, muscle functionality, most plasma cytokines (TNF, IL-6, IL-1β and interferon-γ), immunomodulatory proteins (sTNFR1, sTNFR2, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor) or immunomodulatory hormones (adiponectin, insulin and leptin) after supplementation in the WP groups at the two assessed moments. WP supplementation increased the levels of interferon-γ-induced protein-10/CXCL10 (P = 0·022), eotaxin-1/CCL11 (P = 0·031) and monocyte chemoattractant protein-1/CCL2 (P = 0·018) and decreased IL-5 (P = 0·027), including among those in the MELD ≥ 15 group, for whom IL-10 was also increased (P = 0·008). Thus, WP consumption by patients with CLD impacted the immunomodulatory responses when compared with CA with no impact on nutritional status.

Lutein supplementation combined with a low calorie diet in the middle-aged obese individuals: effects on anthropometric indices, body composition, and metabolic parameters

2020 ◽  
pp. 1-32
Author(s):  
Fatemeh Hajizadeh-Sharafabad ◽  
Ali Tarighat-Esfanjani ◽  
Zohreh Ghoreishi ◽  
Mehrnoosh Sarreshtedari
Keyword(s):  
Body Composition ◽  
Placebo Group ◽  
Lipid Profile ◽  
Glucose Homeostasis ◽  
Density Lipoprotein ◽  
Metabolic Parameters ◽  
Middle Aged ◽  
Anthropometric Indices ◽  
Low Calorie Diet ◽  
Calorie Diet

Abstract Lutein is considered as a major biologically active carotenoid, with potential benefits for obesity and cardiometabolic health. This double-blind, randomized controlled trial aimed to assess whether the consumption of lutein along with a low calorie diet (LCD) can influence anthropometric indices, body composition, and metabolic parameters in obese middle-aged individuals. After a 2-week run-in period with an LCD, 48 participants aged 45–65 y were randomly assigned to consume 20 mg/d lutein or placebo along with LCD for 10 weeks. Dietary intake, anthropometric indices, body composition, lipid profile, glucose homeostasis parameters, non-esterified fatty acids (NEFAs), and appetite sensations were assessed at the beginning and end of the study. After 10 weeks, body weight, and waist circumference significantly decreased in both groups, although between-group differences were not significant. There was a more decrease in the percentage of body fat in the lutein group vs. the placebo group. Moreover, the placebo group experienced a significant reduction in fat free mass (FFM), whereas lutein group preserved FFM during calorie restriction, although between-group difference did not reach statistical significance. Visceral fat and serum levels of total cholesterol (TC) and low-density lipoprotein-cholesterol were significantly decreased only in the lutein group, with a statistically significant difference between two arms only for TC. No significant changes were observed in the triglyceride, high-density lipoprotein-cholesterol, glucose homeostasis parameters, NEFAs, and appetite sensations. Lutein supplementation in combination with an LCD could improve body composition and lipid profile in obese middle-aged individuals.

scholarly journals Body composition and appetite: fat-free mass (but not fat mass or BMI) is positively associated with self-determined meal size and daily energy intake in humans

2011 ◽  
Vol 107 (3) ◽  
pp. 445-449 ◽  
Author(s):  
John E. Blundell ◽  
Phillipa Caudwell ◽  
Catherine Gibbons ◽  
Mark Hopkins ◽  
Erik Näslund ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Food Intake ◽  
Energy Intake ◽  
Fat Mass ◽  
Meal Size ◽  
Fat Free Mass ◽  
Daily Energy Intake ◽  
Molecular Control ◽  
Daily Energy

The idea of body weight regulation implies that a biological mechanism exerts control over energy expenditure and food intake. This is a central tenet of energy homeostasis. However, the source and identity of the controlling mechanism have not been identified, although it is often presumed to be some long-acting signal related to body fat, such as leptin. Using a comprehensive experimental platform, we have investigated the relationship between biological and behavioural variables in two separate studies over a 12-week intervention period in obese adults (totaln92). All variables have been measured objectively and with a similar degree of scientific control and precision, including anthropometric factors, body composition, RMR and accumulative energy consumed at individual meals across the whole day. Results showed that meal size and daily energy intake (EI) were significantly correlated with fat-free mass (FFM,Pvalues < 0·02–0·05) but not with fat mass (FM) or BMI (Pvalues 0·11–0·45) (study 1,n58). In study 2 (n34), FFM (but not FM or BMI) predicted meal size and daily EI under two distinct dietary conditions (high-fat and low-fat). These data appear to indicate that, under these circumstances, some signal associated with lean mass (but not FM) exerts a determining effect over self-selected food consumption. This signal may be postulated to interact with a separate class of signals generated by FM. This finding may have implications for investigations of the molecular control of food intake and body weight and for the management of obesity.

scholarly journals Are Body Composition Parameters Better than Conventional Anthropometric Measures in Predicting Pediatric Hypertension?

2020 ◽  
Vol 17 (16) ◽  
pp. 5771
Author(s):  
Chih-Yu Hsu ◽  
Rong-Ho Lin ◽  
Yu-Ching Lin ◽  
Jau-Yuan Chen ◽  
Wen-Cheng Li ◽  
...  
Keyword(s):  
Body Composition ◽  
Receiver Operating Characteristic Curve ◽  
Operating Characteristic ◽  
Characteristic Curve ◽  
Fat Free Mass ◽  
Z Score ◽  
Pediatric Hypertension ◽  
Anthropometric Measures ◽  
Operating Characteristic Curve ◽  
Better Than

Body composition (BC) parameters are associated with cardiometabolic diseases in children; however, the importance of BC parameters for predicting pediatric hypertension is inconclusive. This cross-sectional study aimed to compare the difference in predictive values of BC parameters and conventional anthropometric measures for pediatric hypertension in school-aged children. A total of 340 children (177 girls and 163 boys) with a mean age of 8.8 ± 1.7 years and mean body mass index (BMI) z-score of 0.50 ± 1.24 were enrolled (102 hypertensive children and 238 normotensive children). Significantly higher values of anthropometric measures (BMI, BMI z-score, BMI percentile, waist-to-height ratio) and BC parameters (body-fat percentage, muscle weight, fat mass, fat-free mass) were observed among the hypertensive subgroup compared to their normotensive counterparts. A prediction model combining fat mass ≥ 3.65 kg and fat-free mass ≥ 34.65 kg (area under the receiver operating characteristic curve = 0.688; sensitivity = 66.7%; specificity = 89.9%) performed better than BMI alone (area under the receiver operating characteristic curve = 0.649; sensitivity = 55.9%; specificity = 73.9%) in predicting hypertension. In conclusion, BC parameters are better than anthropometric measures in predicting pediatric hypertension. BC measuring is a reasonable approach for risk stratification in pediatric hypertension.

scholarly journals Effects of Sweet-Liking on Body Composition Depend on Age and Lifestyle: A Challenge to the Simple Sweet-Liking—Obesity Hypothesis

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2702
Author(s):  
Vasiliki Iatridi ◽  
Rhiannon M. Armitage ◽  
Martin R. Yeomans ◽  
John E. Hayes
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Weight Maintenance ◽  
Age Groups ◽  
Hierarchical Cluster ◽  
Food Choices ◽  
Fat Free Mass ◽  
Obesogenic Environment ◽  
Anthropometric Measures ◽  
The Uk

Taste hedonics drive food choices, and food choices affect weight maintenance. Despite this, the idea that hyper-palatability of sweet foods is linked to obesity development has been controversial for decades. Here, we investigate whether interpersonal differences in sweet-liking are related to body composition. Healthy adults aged 18–34 years from the UK (n = 148) and the US (n = 126) completed laboratory-based sensory tests (sucrose taste tests) and anthropometric measures (body mass index; BMI, body fat; fat-free mass; FFM, waist/hips circumferences). Habitual beverage intake and lifestyle and behavioural characteristics were also assessed. Using hierarchical cluster analysis, we classified participants into three phenotypes: sweet liker (SL), sweet disliker (SD), and inverted-U (liking for moderate sweetness). Being a SD was linked to higher body fat among those younger than 21 years old, while in the older group, SLs had the highest BMI and FFM; age groups reflected different levels of exposure to the obesogenic environment. FFM emerged as a better predictor of sweet-liking than BMI and body fat. In the older group, sweetened beverage intake partially explained the phenotype–anthropometry associations. Collectively, our findings implicate underlying energy needs as an explanation for the variation in sweet-liking; the moderating roles of age and obesogenic environment require additional consideration.

Sign in / Sign up

Export Citation Format

Share Document