scholarly journals Chronic sclerosing sialadenitis: report of a rare and atypical case

2021 ◽  
Vol 10 (6) ◽  
pp. 917-920
Author(s):  
Rafaela Savio Melzer ◽  
Cintia Mussi Milani ◽  
Fernanda Noguez Sum ◽  
Rui Cesar de Bittencourt Druszcz ◽  
Juliana Lucena Schussel
Keyword(s):  
Complete Resolution ◽  
Clinical Characteristics ◽  
Clinical Case ◽  
Benign Lesion ◽  
Surgical Excision ◽  
Malignant Neoplasms ◽  
Atypical Case ◽  
Chronic Sclerosing Sialadenitis ◽  
Recommended Treatment ◽  
Male Patients

A Chronic Sclerosing Sialodenitis is a rare and benign lesion that preferentially affects a submandibular gland of male patients. Although its etiology is considered unknown, it is suggested that the secretion of IgG4 immunoglobulin may be useful for its manifestation. This pathology has specific clinical characteristics for malignant neoplasms of the salivary glands, where the recommended treatment is a surgical excision. The present study presents an atypical case of chronic sclerosing sialodenitis that involves a woman's soft palate, where there was a complete resolution of the clinical case, in which the conservative treatment was chosen by the use of medications.

scholarly journals Verruciform xanthoma: case report

2016 ◽  
Vol 64 (1) ◽  
pp. 79-82
Author(s):  
Maria Carolina de Lima Jacy MONTEIRO ◽  
Cristiane FURUSE ◽  
Larissa Cunha CÊ ◽  
Alexandre Freitas SANTANA ◽  
Vera Cavalcanti de ARAÚJO
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Benign Lesion ◽  
Viral Origin ◽  
Pathogenic Mechanisms ◽  
Verruciform Xanthoma ◽  
Local Trauma

ABSTRACT Verruciform xanthoma is a rare, benign lesion, with a papillary aspect, asymptomatic, sessile, white colored, and well-demarcated, that occurs in the gingiva and alveolar mucosa. The histopathological aspect is characterized by the presence of macrophages with foam cytoplasm (xanthoma cells) confined to the soft papillary tissue. The etiology and pathogenic mechanisms are unknown, although some hypothesis, such as local trauma or viral origin have been suggested. The aim of this article was report a clinical case of verruciform xanthoma located in the gingiva showing the clinical and histopathological aspects.

Adenomatoid odontogenic tumor: a report of two unusually large lesions in the mandible

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S88-S89
Author(s):  
A Lazim ◽  
R Kuklani ◽  
D Sundararajan
Keyword(s):  
Benign Neoplasm ◽  
Surgical Excision ◽  
Odontogenic Tumor ◽  
Radiographic Examination ◽  
Adenomatoid Odontogenic Tumor ◽  
Impacted Tooth ◽  
Anterior Maxilla ◽  
Recommended Treatment ◽  
First Case ◽  
The Right

Abstract Introduction/Objective Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic tumor representing 3 to 7% of all odontogenic tumors. This tumor was first reported as adeno-ameloblastoma by Bernier and Tiecke in 1950 as it was initially assumed to be a type of ameloblastoma. In 1969, Philipsen and Bern proposed the term adenomatoid odontogenic tumor which was subsequently adopted by WHO and became the accepted terminology for this tumor. AOT is classified as a tumor of odontogenic epithelium but occasionally abnormal hard tissues consistent with dentinoid material may also be present as part of the tumor. AOT tends to occur in younger patients and 50% of the cases are diagnosed in teenagers. It occurs twice as commonly in females and frequently involves the anterior maxilla. Radiographically, AOT can appear as a radiolucent or mixed lucent-opaque lesion and may be associated with an impacted tooth. Methods/Case Report We report two unusually large expansile lesions of AOT that presented in the mandible. In the first case, the tumor presented as an expansile radiolucent lesion involving the right posterior mandible in a 32 year old female. In the second case, the tumor presented as an expansile mixed lucent-opaque lesion involving the left anterior mandible in a 21 year old female. The clinical presentation, radiographic and imaging findings, histopathologic features and treatment of these two cases will be discussed. The recommended treatment for AOT is surgical excision. The prognosis is good as this tumor seldom recurs after excision. Results (if a Case Study enter NA) NA Conclusion AOT is considered to be a non-aggressive, non-invasive and slow growing benign neoplasm. It is usually discovered on routine radiographic examination as the lesion is usually small and asymptomatic at the time of diagnosis but occasional cases that are larger in size have been reported in the literature.

scholarly journals Clinical Characteristics of Auricular Keloids Treated with Surgical Excision

2012 ◽  
Vol 16 (3) ◽  
pp. 134 ◽  
Author(s):  
So Young Park ◽  
Guen-Ho Lee ◽  
Jung Mee Park ◽  
Sang-Gyun Jin ◽  
Jeong-Hoon Oh
Keyword(s):  
Clinical Characteristics ◽  
Surgical Excision

scholarly journals Sex-Disaggregated Data on Clinical Characteristics and Outcomes of Hospitalized Patients With COVID-19: A Retrospective Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Mengdie Wang ◽  
Nan Jiang ◽  
Changjun Li ◽  
Jing Wang ◽  
Heping Yang ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Clinical Characteristics ◽  
Random Effect ◽  
Hospitalized Patients ◽  
Male And Female ◽  
Female Patients ◽  
Disease Outcomes ◽  
Male Patients

BackgroundSex and gender are crucial variables in coronavirus disease 2019 (COVID-19). We sought to provide information on differences in clinical characteristics and outcomes between male and female patients and to explore the effect of estrogen in disease outcomes in patients with COVID-19.MethodIn this retrospective, multi-center study, we included all confirmed cases of COVID-19 admitted to four hospitals in Hubei province, China from Dec 31, 2019 to Mar 31, 2020. Cases were confirmed by real-time RT-PCR and were analyzed for demographic, clinical, laboratory and radiographic parameters. Random-effect logistic regression analysis was used to assess the association between sex and disease outcomes.ResultsA total of 2501 hospitalized patients with COVID-19 were included in the present study. The clinical manifestations of male and female patients with COVID-19 were similar, while male patients have more comorbidities than female patients. In terms of laboratory findings, compared with female patients, male patients were more likely to have lymphopenia, thrombocytopenia, inflammatory response, hypoproteinemia, and extrapulmonary organ damage. Random-effect logistic regression analysis indicated that male patients were more likely to progress into severe type, and prone to ARDS, secondary bacterial infection, and death than females. However, there was no significant difference in disease outcomes between postmenopausal and premenopausal females after propensity score matching (PSM) by age.ConclusionsMale patients, especially those age-matched with postmenopausal females, are more likely to have poor outcomes. Sex-specific differences in clinical characteristics and outcomes do exist in patients with COVID-19, but estrogen may not be the primary cause. Further studies are needed to explore the causes of the differences in disease outcomes between the sexes.

scholarly journals GYNAECOMASTIA

2010 ◽  
Vol 17 (02) ◽  
pp. 205-210
Author(s):  
ASIYA SHABBIR ◽  
TARIQ MAHMOOD REHAN ◽  
SHAHID Hussain Jaffery ◽  
Muhammad Ubaidullah Baig
Keyword(s):  
Benign Lesion ◽  
Case Series ◽  
Spontaneous Resolution ◽  
Subcutaneous Mastectomy ◽  
Appropriate Treatment ◽  
Case Series Study ◽  
Causative Factors ◽  
Male Patients ◽  
Series Study ◽  
Surgical Unit

Objectives: To determine the causative factors and management of Gynaecomastia. Study Design: Observational case series study. Place and Duration of Study: Surgical Unit-1 Bahawal Victoria Hospital Bahawalpur, from 1st January 200 till 31st December 2007. Patient and Methods: Thirty male patients having breast swelling were included in this study. Relevant history was obtained. Appropriate physical examination was performed. Necessary investigations were done and after making a diagnosis appropriate treatment was done. A total of 30 patients were studied in the study period of 18 months. Those male patients who were having breast lesion other than benign enlargement (e.g. Ca. Breast, Breast/Abscess) were not included in the study. Necessary investigations were done. Subcutaneous Mastectomy was performed. Results: The most common age group developing gynaecomastia was of 20-30 years (60%). Bilateral gynaecomastia was observed in 76.66% and unilateral gynaecomastia in 23.33%. Idiopathic gynaecomastia was observed in 73.33% cases. Medical treatment was given with tamoxifen 10mg twice a day for the period of three months in 6 case (20%) and this remained effective in 5 case (83.33%). Subcutaneous mastectomy was performed in 17 cases (56.66%). Post-operative complications were seen in 4 cases (23.52%), the most common complication being wound hematoma in 2 cases (11.76%). Most of the patients (88.9%) were fully satisfied with the results of subcutaneous mastectomy. Conclusion: Gynaecomastia is the most common benign lesion of the male breast. As far as physiological gynaecomastia is concerned, patients should be observed for at least 2 years from the onset of their condition. In most of the cases spontaneous resolution occurs. Surgical treatment should be planned in whom spontaneous resolution does not occur. Surgery remains the mainstay of therapy and is frequently indicated for psychological and cosmetic reasons. 

scholarly journals Efficacy of Diode Laser in Treating Oral Papilloma: A Case Report

2021 ◽  
Vol 15 (1) ◽  
pp. 262-265
Author(s):  
Wallena A. da Cunha ◽  
Ana M. A. Souza ◽  
Paulo S. S. Pina ◽  
Luciane H. Azevedo
Keyword(s):  
Diode Laser ◽  
High Intensity ◽  
Clinical Characteristics ◽  
Clinical Case ◽  
Soft Tissue Mass ◽  
Oral Lesions ◽  
Conventional Surgery ◽  
Tissue Mass ◽  
Case Presentation ◽  
Squamous Papilloma

Background: Oral squamous papilloma is the most common lesion caused by the Human Papillomavirus (HPV). They are benign proliferation, often painless, and with cauliflower or verrucous appearance. Objective: The aim of this report is to describe a clinical case of oral squamous papilloma and its treatment with a high-intensity diode laser. Case Presentation: A 65-year-old female patient sought care at the Special Laboratory of Lasers in Dentistry (LELO), University of São Paulo, Brazil, complaining of growth of a soft tissue mass in the jugal mucosa. Based on these clinical characteristics and history, Papilloma was the initial clinical diagnosis of the lesion. Although the lesion was small in size, measuring approximately 0.5 cm, the diagnostic method used was biopsy, and for treatment, a high-intensity diode laser at a wavelength of 980 nm was used. Conclusion: It can be concluded that Laser Therapy can be used by dental clinicians to treat these kinds of oral lesions and should be considered as an effective alternative to conventional surgery.

scholarly journals Horizons of development of immunotherapy for malignant liver tumors

2021 ◽  
pp. 81-89
Author(s):  
V. E. Mukhin ◽  
Yu. S. Konstantinova ◽  
R. R. Gimadiev ◽  
N. V. Mazurchik
Keyword(s):  
Liver Tumors ◽  
Surgical Excision ◽  
Malignant Neoplasms ◽  
Therapeutic Approaches ◽  
Liver Malignancies ◽  
Primary Liver Tumors ◽  
Malignant Liver Tumors ◽  
Malignant Liver ◽  
Methods Of Treatment ◽  
New Strategies

Primary liver tumors are one of the most common types of malignant neoplasms. Surgical excision is still the most effective treatment in the early stages of the disease, however in most cases early diagnosis is difficult. Moreover, even if the treatment is carried out according to a radical program, the risk of relapse remains extremely high. In this regard, the search for new strategies for the treatment of liver malignancies that differ from traditional methods of treatment is not terminated. One of such promising approaches is immunotherapy. The present review is devoted to the current understanding of the mechanisms of action and the available clinical experience in the use of immunotherapy approaches in the treatment of liver malignancies. Combining different types of immunotherapy or combining immunotherapy with traditional therapeutic approaches can facilitate a synergistic effect and contribute to the development of personalized medicine.

scholarly journals Pilomatrixoma, a Rare Mimicker of Male Breast Cancer

2019 ◽  
Vol 9 ◽  
pp. 46
Author(s):  
Aurela Clark ◽  
Rebecca Leddy ◽  
Laura Spruill ◽  
Abbie Cluver
Keyword(s):  
Benign Lesion ◽  
Surgical Excision ◽  
Male Breast ◽  
Skin Tumor ◽  
Imaging Features ◽  
Histologic Diagnosis ◽  
Outer Quadrant ◽  
Imaging Characteristics ◽  
Suspicious Feature

Pilomatrixoma or calcifying epithelioma of Malherbe is a benign skin tumor arising from the hair follicle; breast occurrence is considered a rarity. Clinically presenting as a palpable abnormality and with both benign and malignant mammographic and sonographic features, it can be easily misdiagnosed as a breast neoplasm. We report a very rare case of pilomatrixoma of the male breast in a 36-year-old male presenting with a firm, superficial nodule in the upper outer quadrant. Though the sonographic trifecta of imaging features (shape- margins-orientation/oval, circumscribed mass, parallel to the skin) is consistent with a benign lesion, a histologic diagnosis was warranted based on its most suspicious feature of internal pleomorphic calcifications. Pathologic diagnosis revealed the uncommon benign entity of pilomatrixoma in the male breast. Our patient was recommended for surgical excision based on current literature recommendations for management in most reports of pilomatrixoma. One alternative recommendation presented in a single report of pilomatrixoma in the breast supported follow-up imaging based on benign imaging characteristics.

Sclerosing Hemangioma of the Lung

2009 ◽  
Vol 133 (5) ◽  
pp. 820-825 ◽  
Author(s):  
C. P. T. Joren B. Keylock ◽  
Jeffrey R. Galvin ◽  
Teri J. Franks
Keyword(s):  
Regional Lymph Node ◽  
Benign Lesion ◽  
Surgical Excision ◽  
Cell Types ◽  
Additional Treatment ◽  
Term Survival ◽  
Sclerosing Hemangioma ◽  
Architectural Patterns ◽  
Node Metastases

Abstract We present a brief review of sclerosing hemangioma, an uncommon but histologically distinctive neoplasm of the lung. Based on immunohistochemical and molecular findings, sclerosing hemangioma is thought to be derived from incompletely differentiated respiratory epithelium. Sclerosing hemangiomas typically present as asymptomatic, peripheral, solitary, well-circumscribed lesions in women with a mean age at diagnosis in the fifth decade. Rare cases are reported to have regional lymph node metastases; however, metastases do not appear to affect long-term survival. Histologically, sclerosing hemangioma is characterized by a distinct constellation of findings including 2 epithelial cell types, surface cells and round cells, which form 4 architectural patterns, papillary, sclerotic, solid, and hemorrhagic. Sclerosing hemangioma of the lung is generally considered to be a benign lesion, and surgical excision is curative without the need for additional treatment.

scholarly journals An unusual pleomorphic adenoma

2014 ◽  
Vol 62 (3) ◽  
pp. 319-324
Author(s):  
Christiano Sampaio QUEIROZ ◽  
Roberto Almeida de AZEVEDO ◽  
Antonio Irineu TRINDADE NETO ◽  
Caetano Guilherme Carvalho PONTES ◽  
Rafael de Queiroz MOURA
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Histopathological Examination ◽  
Minor Salivary Gland ◽  
Surgical Excision ◽  
Biological Behavior ◽  
Surgical Removal ◽  
Minor Salivary Glands ◽  
Recommended Treatment

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.

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