scholarly journals Implications of the use of Strontium Ranelate (SRAN) in periodontics, dental implantology, oral surgery, orthodontics and endodontics and its possibility of application as storage media for avulsed teeth

2021 ◽  
Vol 10 (9) ◽  
pp. 1517-1524
Author(s):  
Amanda Cristine dos Santos Britto ◽  
Priscila Bruna Gonçalves Lacerda ◽  
Victor Eduardo de Souza Batista ◽  
Christine Men Martins
Keyword(s):  
Bone Tissue ◽  
Strontium Ranelate ◽  
Root Resorption ◽  
Oral Surgery ◽  
Public Health Problem ◽  
Laboratory Studies ◽  
Tooth Avulsion ◽  
Storage Media ◽  
Dental Avulsion ◽  
Topical Applications

Dental avulsion is still public health problem and tooth replantation has important unsuccess rates due to root resorption. Strontium ranelate (SRAN) presents antiresorptive property on the bone tissue and stimulates bone formation. So we aimed to comprehensively review the literature to 1- understand the mechanism of action of SRAN regarding to its propaedeutic in periodontics, dental implantology, oral surgery, orthodontics and endodontics, 2- present the current scientific knowledge about the SRAN efficiency on tooth avulsion; 3- observe fails and gaps in the literature and open up for unexplored ideas for SRAN uses and applications. An electronic search was performed crossing the key words ‘strontium ranelate’, ‘periodontics’, ‘dental implantology’, ‘oral surgery’, ‘orthodontics’ and ‘endodontics’, PubMed/Medline, Lilacs and BBO electronic databases were searched for research articles, reviews of literature, animal laboratory studies and laboratory studies, which had been published in English until July 2020. Twenty-five articles fulfilled the inclusion and exclusion criteria. The available literature demonstrates that SRAN provides a really better propaedeutic on the bone tissue and that the topical applications show a lower risk of side effects. That open up new perspectives and for the use of SRAN as a potential storage media for avulsed teeth.

THE INFLUENCE OF SORPTION-DETOXIFYING MEANS ON CUMULATION OF 90SR IN BONE TISSUE OF WHITE RATES WITH COMBINED INTAKE OF 137CS, CD AND PB

2018 ◽  
Vol 1 (3) ◽  
pp. 129-133
Author(s):  
L. L. Zakharova ◽  
◽  
G. A. Zhorov ◽  
V. N. Obryvin ◽  
◽  
...  
Keyword(s):  
Bone Tissue ◽  
Chemical Nature ◽  
Mechanisms Of Action ◽  
The Body ◽  
Biologically Active ◽  
Laboratory Studies ◽  
Animal Body ◽  
White Rats ◽  
Combined Use ◽  
Active Substances

The article presents the results of laboratory studies of the effect of sorption-detoxifying means on the accumulation of 90Sr in the body of white rats. The efficiency of a number of selective and polyfunctional sorbents, detoxicants and other biologically active substances and the developed on their basis sorption-detoxifying complexes as means of efferent therapy and detoxification of the animal body at the combined intake of xenobiotics of radiation and chemical nature was evaluated. It was found that 90Sr cumulation in bones (at the level of 53,3–60,8%) was reduced to the greatest extent with the combined use of substances of different mechanisms of action and origin. The effectiveness of separate use of detoxifying drugs did not exceed 29,1%.

Change of Biomechanical Parameters in the Lower Jaws of Rabbits with Experimental Osteoporosis after Implantation of Calcium-Phosphate Bioceramic Material in the Greater Trochanter Region

2016 ◽  
Vol 721 ◽  
pp. 224-228
Author(s):  
Girts Salms ◽  
Vladislavs Ananjevs ◽  
Vladimirs Kasyanovs ◽  
Andrejs Skagers ◽  
Ilze Salma ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Strontium Ranelate ◽  
Biomechanical Properties ◽  
Control Group ◽  
Greater Trochanter ◽  
Lower Jaw ◽  
Experimental Osteoporosis ◽  
Rabbit Bone ◽  
Biomechanical Parameters

Investigation of biomechanical properties of the rabbit bone tissue from a corner of the lower jaw was done. Experimental osteoporosis was induced by ovariectomy and following injections of methylprednisolone. The defects in the greater trochanter region was created and filled with granules of a hydroxyapatite and tricalcium phosphate (HAP/TCP 30/70) or HAP/TCP 30/70 together with 5% strontium ranelate. After 3 month animals were euthanased, squared samples have been cut out from a corner of the lower jaw and tested on a bend. Results of research show, that the corner of a lower jaw in rabbit becomes more rigid after filling of defects in the greater trochanter region with granules of a hydroxyapatite and tricalcium phosphate (HAP/TCP 30/70) or granules together with strontium ranelate. The ultimate strain for the bone tissue in the 2nd and 3rd group is less, than for control group. Thus, local uses calcium – phosphatic bioceramic material around the greater trochanter region improves biomechanical parameters of a bone tissue in the lower jaw of animals.

THE EFFECT OF METHOPRENE, AN INSECT GROWTH REGULATOR, ON MUSCA DOMESTICA (DIPTERA: MUSCIDAE)

1977 ◽  
Vol 107 (4) ◽  
pp. 413-417 ◽  
Author(s):  
Philip B. Morgan ◽  
G. C. LaBrecque ◽  
D. E. Weidhaas ◽  
A. Benton
Keyword(s):  
Weight Loss ◽  
Musca Domestica ◽  
Larval Mortality ◽  
Exposure Period ◽  
Insect Growth Regulator ◽  
Laboratory Studies ◽  
House Flies ◽  
Poultry Droppings ◽  
Topical Applications ◽  
Low Order

AbstractMethoprene, when incorporated into the food of laying hens at concentrations of 0.005 and 0.01%, produced 70.9 and 99.3% larval mortality, respectively, among house flies (Musca domestica L.) reared in the resultant poultry droppings. Exposure to the treated diet did not produce any weight loss in the chickens. However, it was not effective when the poultry droppings were treated topically under field conditions. In laboratory studies, when incorporated with moistened droppings, concentrations of 0.001 and 0.0001% produced complete larval mortality throughout a 7-day exposure period, though only 98% mortality was achieved on the first day at the higher concentration. Concentrations of 0.5 and 1.08 of the compound in fly food produced only a low order of sterility. Topical applications produced a low order of sterility except in the insecticide-susceptible females.

scholarly journals Construction and validation of a podcast for dental surgeons: timely conduction after tooth avulsion

2021 ◽  
Vol 10 (5) ◽  
pp. e54710515086
Author(s):  
Keylla Cação Fernandes ◽  
Elielza Guerreiro Menezes ◽  
Lihsieh Marrero ◽  
Milena Batista de Oliveira
Keyword(s):  
Content Validity ◽  
Preventive Measures ◽  
Methodological Study ◽  
Validity Index ◽  
Index Method ◽  
Content Validity Index ◽  
Tooth Avulsion ◽  
Three Stages ◽  
Dental Avulsion

Objective: Create and validate a podcast for dental surgeons as a guide after a dental avulsion. The validation was done through Google forms. Nine expert judges participated, following four aspects: characterization of the judges, content, functionality and appearance. The quantitative analysis was performed with Excel software to calculate the content validity index. Method: Methodological study with a quantitative and validation approach, carried out in three stages: integrative review of the literature; technology construction; validation of a post-avulsion podcast presented to nine expert judges. A Likert scale was used for data collection. For the analysis, a content validity index ≥ 0.75 was adopted. Results: The Content Validity Index presented values ​​of 0.84% ​​in its structure and presentation, 099% of high relevance for expert judges. Conclusion: The “Al Dente” podcast contains important information on dental reimplantation after an avulsion, resulting in preventive measures that directly influence health services.

scholarly journals Animated Video for Increasing Primary School Teachers’ Knowledge Regarding First Aid Management of Dental Avulsion

2020 ◽  
Vol 23 (4) ◽  
pp. 7p
Author(s):  
Vassa Khema Katthika ◽  
Eva Fauziah ◽  
Sarworini Bagio Budiardjo
Keyword(s):  
Primary School ◽  
School Environment ◽  
First Aid ◽  
School Teachers ◽  
Primary School Teachers ◽  
Tooth Avulsion ◽  
Public Elementary Schools ◽  
Before And After ◽  
Teacher's Knowledge ◽  
Dental Avulsion

Introduction: Dental avulsion is a condition in which the tooth is completely dislodged from its socket. Inappropriate management when trauma occurs can complicate the prognosis of the tooth. The majority of injuries to children's teeth occur in the school environment and teachers play an essential role in providing first aid at the accident site. However, the school teacher’s knowledge regarding first aid dental avulsion is inadequate. Objectives: The purpose of this study was to analyze the effect of an animated video (First Aid Management of Dental Avulsion) on the knowledge of primary school teachers. Materials and methods: This clinical experimental study comprised 54 teachers from 13 public elementary schools in Central Jakarta who were chosen randomly to fill out a questionnaire before and after watching the animated video. Results: Data analysis using the Wilcoxon comparative test showed that there was a statistically significant increase (P<.05) in knowledge after watching the animated video. Conclusion: Thus, the animated video was effective in increasing the knowledge regarding first aid management of dental avulsion among the primary school teachers. Keywords: audiovisual aid; first aid; school teachers; tooth avulsion

scholarly journals Medios de almacenamiento y transporte para dientes avulsionados

2014 ◽  
Vol 10 (2) ◽  
pp. 24
Author(s):  
Carmen Inocencia Quintana del Solar
Keyword(s):  
Storage Medium ◽  
Tooth Avulsion ◽  
Storage Media ◽  
Medium Storage

Se realizó una revisión de la literatura con respecto a los medios de almacenamiento para dientes avulsionados. Se utilizó el buscador Medline, incluyendo aquellas publicaciones entre 1980 - 2007 en las que apareciesen como palabra clave: “viability”, “storage medium”, “storage media”, “tooth avulsion” y “avulsion”. Los mejores medios son aquellos que tienen las siguientes características: pH y osmolalidad fisiológica, contengan nutrientes, sean líquidos estériles y estén disponibles en el lugar del accidente. Los resultados de estos estudios muestran que la leche fresca descremada pasteurizada fue mejor que la saliva, el agua, las soluciones para lentes de contacto y el Gatorade®. El HBSS y el Viaspan fueron mejores que la leche, el propóleo y el agua de coco. El Viaspan fue igual a, o mejor que, el HBSS para preservar las células del ligamento periodontal. A pesar de su efectividad en mantener la viabilidad celular, el Viaspan y el HBSS son costosos y no están disponibles rápidamente en el lugar del accidente a diferencia de la leche.

scholarly journals Replantation after traumatic avulsion

2013 ◽  
Vol 07 (02) ◽  
pp. 229-232 ◽  
Author(s):  
Huseyin Tezel ◽  
Cigdem Atalayin ◽  
Gul Kayrak
Keyword(s):  
Saline Solution ◽  
Root Resorption ◽  
Composite Resin ◽  
Central Incisor ◽  
Maxillary Central Incisor ◽  
Storage Media ◽  
The Moment ◽  
Supporting Structures ◽  
Functional Position

ABSTRACTThe aim of this report is to present the case of an accidentally avulsed maxillary central incisor kept in saline solution from the moment of trauma until its replantation 3 h later in a 13-year-old girl. The avulsed tooth was replanted back into the alveolar socket and splinted with composite resin. Calcium hydroxide intracanal dressing was used to prevent inflammatory root resorption. Radiographic and clinical examinations were performed during 27 months follow-up. During the 15 months follow-up period, the tooth remained in a stable functional position and did not reveal replacement resorption. But mild infraocclusion and root resorption were developed 21 months after replantation. The amount of damage to tooth and supporting structures, emergency treatment and follow-up period play a role in the prognosis of the avulsed tooth. It can be recommended to keep the avulsed tooth in saline solution at least when more appropriate storage media are not on handle immediately.

Conhecimento das enfermeiras da pós-graduação em saúde da família sobre avulsão dentária

2009 ◽  
Vol 3 (2) ◽  
pp. 309
Author(s):  
Ana Cristina Viana Campos ◽  
Daniela Carla Medeiros-Silva ◽  
Flávia Fonseca de Toledo ◽  
Patrícia Maria Pereira de Araújo Zarzar ◽  
Júlio César Batista Santana ◽  
...  
Keyword(s):  
Statistical Methods ◽  
Family Health ◽  
Descriptive Study ◽  
The Other ◽  
Continuous Education ◽  
Attitudes And Practices ◽  
Tooth Avulsion ◽  
The Family ◽  
Belo Horizonte ◽  
Dental Avulsion

ABSTRACT Objectives: to investigate the knowledge, the attitudes and practices of the nurses students' in the specialization in Family Health, of the Institute of Continuous Education in PUC Sete Lagoas city, Belo Horizonte, Brasil. Method: transversal, descriptive, study developed with 17 nurses, students of the Family Health Specialization, with volunteered to participate in the study. It was conducted toward the application of modified questionnaire with the thematic dental avulsion. The data were analyzed by descriptive statistical methods. Results: most of the nurses (71%) never heard before the term “dental avulsion”. Five nurses (29%) would not know which providences is necessary in case of dental avulsion, six (35%) would store the tooth and conduct the person to the dentist, three (18%) just direct the person to the dentist, one nurse (6%) would conduct the person to do the restoration, the other (6%) would store the tooth in milk and would give the tooth to the rescuer, and only one (6%) of them would make the replantation immediately. Conclusions: we can affirm that the analyzed nurses present inadequately knowledge when they were questioned about different aspects of urgency procedures in cases of dental avulsion. Descriptors: tooth avulsion; nursing; family health; oral health.RESUMO  Objetivos: investigar o conhecimento, as atitudes e práticas das enfermeiras alunas da especialização em Saúde da Família do Instituto de Educação Continuada da PUC de Sete Lagoas sobre a avulsão dentária. Método: foi realizado um estudo transversal e descritivo. A população estudada constituiu-se de 17 enfermeiras, alunas do curso de Especialização em Saúde da Família, que se voluntariaram a participar do estudo. Como instrumento para coleta de dados foi utilizado um questionário adaptado, com perguntas acerca da temática avulsão dentária. Os dados obtidos foram submetidos a análises quantitativas, através de métodos estatísticos descritivos. Resultados: a maioria das enfermeiras (71%) nunca ouviu falar de avulsão dentária. Cinco enfermeiras (29%) não saberiam quais as providências necessárias em caso de avulsão dentária, seis (35%) armazenariam o dente e encaminhariam a pessoa ao dentista, três (18%) apenas encaminhariam a pessoa ao dentista, uma enfermeira (6%) encaminharia a pessoa para fazer a restauração, uma aluna (6%) armazenaria o dente em leite e entregaria o dente ao socorrista, e apenas uma (6%) delas faria imediatamente o reimplante. Conclusões: pode-se afirmar que as enfermeiras analisadas não apresentaram conhecimentos sólidos quando questionadas acerca de diferentes aspectos de procedimentos em casos de tratamento de urgência por avulsão dentária ocasional. Descritores: avulsão dentária; enfermagem; saúde da família; saúde bucal.RESUMEN Objetivos: investigar el conocimiento, las actitudes y las prácticas de las enfermeras estudiantes en la especialización de la Salud de la Familia del Instituto de Educação Continuada (IEC) de la PUC Sete Lagoas en la avulsión dental. Métodos: el  estudio descriptivo transversal. La población de estudio consistió de 17 enfermeras, estudiantes del curso de Especialización en Salud de la Familia, que se ofrecieron para participar en el estudio. Como una herramienta para la recolección de datos se utilizó un cuestionario adaptado. Los datos fueron sometidos a análisis cuantitativo, usando los métodos estadísticos descriptivos. Resultados: La mayoría de las enfermeras (71%) nunca oído hablar de la avulsión dental. Cinco enfermeras (29%) no sabía qué hacer en caso de avulsión dental, seis (35%) almacenarían el diente y dirigirían a persona al dentista, tres (18%) dirigirían solamente a persona al dentista, una enfermera (6% ) ordenarían a persona hacer la restauración, un estudiante (6%) almacenarían el diente en leche y entregarían el diente al socorrista, y sólo uno (6%) de ellos haría el reimplante inmediatamente. Conclusiones: Puede ser afirmado que las enfermeras analizadas no habían presentado conocimiento sólido preguntado al referirse a diversos aspectos de procedimientos en casos del tratamiento de la urgencia para la avulsión dental occasional. Descriptores: Avulsión Dental; Enfermería; Salud de la Família; Salud Bucal.

scholarly journals Strontium ranelate promotes increased peri-implant bone formation in ovariectomized rats.

2020 ◽  
Vol 9 (10) ◽  
pp. e7539109092
Author(s):  
Fernanda Costa Yogui ◽  
Ana Cláudia Ervolino-Silva ◽  
Letícia Pitol-Palin ◽  
Juliana Zorzi Coléte ◽  
Jaqueline Suemi Hassumi ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Bone Formation ◽  
Bone Tissue ◽  
Strontium Ranelate ◽  
Statistical Tests ◽  
Ovariectomized Rats ◽  
Pcr Analysis ◽  
Adult Rats ◽  
Alizarin Red ◽  
Reverse Torque

This study aimed to evaluate the systemic effect of strontium ranelate (SR) on peri-implant bone tissue. Thirty-six adult rats were divided into three experimental groups: sham (SHAM), ovariectomized (OVX) and ovariectomized rats treated with strontium ranelate (OVX-Sr). Strontium ranelate (625mg/kg) was administered by oral gavage on a daily basis. The implants were installed on the tibiae. The euthanasia occurred 42 and 60 days after the implants were installed, and the biomechanical (reverse torque); PCR-RT; histological; immunohistochemical; confocal microscopy and histometric analysis were performed. Quantitative data was subjected to statistical tests with significance level set at p<0.05. Significant increase in implant reverse torque in OVX-Sr was observed when compared to OVX. PCR analysis showed an increase in the genetic expression of the proteins responsible for bone formation in OVX-SR. In the histological analysis, SHAM and OVX-Sr showed a higher degree of maturation of peri-implant bone tissue. Ran-Sr presented higher immunolabeling for ALP and OPN proteins when compared to OVX. In the confocal microscopy, OVX-Sr there was good bone neoformation showed by incorporation of Alizarin red fluorochrome. The histometric analysis, bone implant contact (BIC) and neoformed bone area (NBA) presented statistically difference among all groups, and the Ran-Sr presented the highest BIC. Thus, strontium ranelate improves osseointegration and quality of neoformed bone tissue around implants in estrogen deficient rats.

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